Revue Fran?aise de Transfusion et Immuno-hématologie最新文献

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Idiotypic specificities of anti-Rhesus (D) monoclonal antibodies 抗恒河猴(D)单克隆抗体的独特型特异性
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80110-7
P. Lambin , Ph. Rouger , N. Herance , M. Debbia , J.M. Fine , Ch. Salmon
{"title":"Idiotypic specificities of anti-Rhesus (D) monoclonal antibodies","authors":"P. Lambin , Ph. Rouger , N. Herance , M. Debbia , J.M. Fine , Ch. Salmon","doi":"10.1016/S0338-4535(88)80110-7","DOIUrl":"10.1016/S0338-4535(88)80110-7","url":null,"abstract":"","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 245-248"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80110-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14276771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal antibodies against glycophorins 抗糖蛋白单克隆抗体
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80112-0
E. Lisowska , K. Waśniowska , E. Jaśkiewicz , M. Czerwiński , I. Steuden
{"title":"Monoclonal antibodies against glycophorins","authors":"E. Lisowska ,&nbsp;K. Waśniowska ,&nbsp;E. Jaśkiewicz ,&nbsp;M. Czerwiński ,&nbsp;I. Steuden","doi":"10.1016/S0338-4535(88)80112-0","DOIUrl":"10.1016/S0338-4535(88)80112-0","url":null,"abstract":"<div><p>Glycophorins of human erythrocytes have been extensively studied and the structure of three of them is fully (glycophorins A and C) or almost fully (glycophorin B) known [1, 2]. Glycophorins span the erythrocyte membrane and their NH<sub>2</sub>-terminal domains exposed at the cell surface are heavily glycosylated. Glycophorin A occurs in two genetically determined forms carrying at NH<sub>2</sub>-terminal end blood group M and N antigenic determinants. Glycophorin B (blood group Ss glycoprotein) has the structure of NH<sub>2</sub>-terminal region (a.a. residues 1–26) identical to glycophorin A of blood type N, and also shows a high degree of homology with glycophorin A in the internal portion of the molecule, whereas glycophorin C has a different amino acid sequence. The knowledge of structure and orientation in the membrane and genetic differentiation of glycophorins facilitate elucidation of the fine specificity of anti-glycophorin antibodies.</p><p>The 30 anti-glycophorin-antibodies obtained were tested by agglutination of untreated and modified erythrocytes, immunoblotting, and binding to glycophorin A in microtiter plate ELISA. Moreover, inhibition of antibodies by untreated and modified glycophorin A preparations was studied. The methods used were described in detail in our recent publications [3, 5].</p><p>The antibodies could be divided into groups <em>(Table I)</em>, depending on specificity. The 19 antibodies recognized epitopes located at the NH<sub>2</sub>-terminal end of glycophorin A that could be easily shown by specific or distinctly preferable reactivity with blood group M (8 MoAbs) or N (11 MoAbs) antigen. The antibodies with anti-N specificity also reacted with glycophorin B. Among the remaining blood group MN-unrelated antibodies, 4 were specific for glycophorin A, 3 recognized epitopes common for glycophorins A and B, 2 reacted to glycophorin C, and the specificity of 2 antibodies could not be clearly established. The antibodies in each group differed in sub-specificity and antigen-binding properties.</p></div>","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 261-271"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80112-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13609478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary serological studies on 31 samples of monoclonal antibodies directed against red cell glycophorins 31份红血球糖蛋白单克隆抗体的初步血清学研究
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80113-2
T. Zelinski, G. Coghlan, E. Belcher, S. Philipps, H. Kaita, M. Lewis
{"title":"Preliminary serological studies on 31 samples of monoclonal antibodies directed against red cell glycophorins","authors":"T. Zelinski,&nbsp;G. Coghlan,&nbsp;E. Belcher,&nbsp;S. Philipps,&nbsp;H. Kaita,&nbsp;M. Lewis","doi":"10.1016/S0338-4535(88)80113-2","DOIUrl":"10.1016/S0338-4535(88)80113-2","url":null,"abstract":"","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 273-279"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80113-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14342205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Co-ordinated report of studies on monoclonal antibodies to complement 单克隆抗体补体的协同研究报告
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80123-5
D. Voak
{"title":"Co-ordinated report of studies on monoclonal antibodies to complement","authors":"D. Voak","doi":"10.1016/S0338-4535(88)80123-5","DOIUrl":"10.1016/S0338-4535(88)80123-5","url":null,"abstract":"","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 367-368"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80123-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14342213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Immunological specificities of four Lutheran related monoclonal antibodies 四种路德相关单克隆抗体的免疫学特异性
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80136-3
Ph. Rouger, G. Liberge, P. Gane, Ch. Salmon
{"title":"Immunological specificities of four Lutheran related monoclonal antibodies","authors":"Ph. Rouger,&nbsp;G. Liberge,&nbsp;P. Gane,&nbsp;Ch. Salmon","doi":"10.1016/S0338-4535(88)80136-3","DOIUrl":"10.1016/S0338-4535(88)80136-3","url":null,"abstract":"<div><p>In this trial, we have tested four monoclonal antibodies related to the Lutheran System. These antibodies were studied by serological methods with a panel of red cells of Lutheran common phenotypes and weak variants.</p></div>","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 441-446"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80136-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14342225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Index des auteurs 作者索引
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80143-0
{"title":"Index des auteurs","authors":"","doi":"10.1016/S0338-4535(88)80143-0","DOIUrl":"https://doi.org/10.1016/S0338-4535(88)80143-0","url":null,"abstract":"","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 485-486"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80143-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136478062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of anti-glycophorin monoclonal antibodies 抗糖蛋白单克隆抗体的鉴定
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80115-6
R.H. Fraser, M.T. Murphy, G. Inglis, R. Mitchell
{"title":"Characterization of anti-glycophorin monoclonal antibodies","authors":"R.H. Fraser,&nbsp;M.T. Murphy,&nbsp;G. Inglis,&nbsp;R. Mitchell","doi":"10.1016/S0338-4535(88)80115-6","DOIUrl":"10.1016/S0338-4535(88)80115-6","url":null,"abstract":"<div><p>This group of mouse monoclonal reagents comprised 31 different antibodies, 19 in the form of culture supernatants and 12 as ascitic fluids. The isotypes of antibodies in supernatant form were determined using a sandwich ELISA immunodot assay, before performing initial serological and physicochemical characterisation by microplate haemagglutination. Culture supernatants were titred without prior dilution, whereas ascitic fluids and purified supernatants were initially diluted 1 : 50 and 1 : 10 respectively in isotonic saline containing 1 % (w/v) BSA before titration. In order to determine their optimal reaction parameters, each antibody was titred at 22° C against selected M + N −, M + N + and M − N + cells at 3 different pH values − 5.5, 7.0 and 8.5. Those giving negative reactions were subjected to an indirect antiglobulin test and were then retested at 37° C and 4° C using optimal pH. Some antibodies were later found to require pretreatment with neuraminidase to induce haemagglutination.</p><p>Each antibody was subsequently tested, at optimal pH and temperature, with the same M + N −, M + N + and M − N + cells, pretreated with the proteolytic enzymes ficin, trypsin and chymotrypsin plus the exoglycosidase, neuraminidase from <em>Vibrio cholerae</em>. Where necessary, more extensive pH studies or sequential enzyme pretreatment of cells were performed before the antibodies were divided into 3 groups - those with anti - M - like specificity, anti - N - like specificity or those showing no specificity for M - or N - antigens. Each group was then tested with selected variant cells and those with apparent anti-carbohydrate specificities were subjected to absorption with synthetic oligosaccharides linked to inorganic carriers (SYNSORBS).</p></div>","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 289-296"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80115-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14342207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary serological studies of 4 monoclonal antibody samples with « Lutheranspecificities 4个具有lutheran特异性的单克隆抗体样本的初步血清学研究
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-04-01 DOI: 10.1016/S0338-4535(88)80134-X
T. Zelinski, H. Kaita, M. Lewis
{"title":"Preliminary serological studies of 4 monoclonal antibody samples with « Lutheranspecificities","authors":"T. Zelinski,&nbsp;H. Kaita,&nbsp;M. Lewis","doi":"10.1016/S0338-4535(88)80134-X","DOIUrl":"10.1016/S0338-4535(88)80134-X","url":null,"abstract":"","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 429-432"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80134-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14342224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Dosage de la pepsine résiduelle dans les immunoglobulines à usage intraveineux 静脉注射用免疫球蛋白中胃蛋白酶残留的测定
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-01-01 DOI: 10.1016/S0338-4535(88)80066-7
C. Reuge
{"title":"Dosage de la pepsine résiduelle dans les immunoglobulines à usage intraveineux","authors":"C. Reuge","doi":"10.1016/S0338-4535(88)80066-7","DOIUrl":"10.1016/S0338-4535(88)80066-7","url":null,"abstract":"<div><p>A method developed in this paper allows to measure the amount of pepsin in the intraveinous immunoglobulin preparation.</p></div>","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 1","pages":"Pages 61-63"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80066-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14265911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Les banques de donnees biomedicales 生物医学数据库
Revue Fran?aise de Transfusion et Immuno-hématologie Pub Date : 1988-01-01 DOI: 10.1016/S0338-4535(88)80074-6
Clarisse Holik, Marie-Claire Guiet
{"title":"Les banques de donnees biomedicales","authors":"Clarisse Holik,&nbsp;Marie-Claire Guiet","doi":"10.1016/S0338-4535(88)80074-6","DOIUrl":"10.1016/S0338-4535(88)80074-6","url":null,"abstract":"","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 1","pages":"Pages 97-98"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80074-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"106974475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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