Revista Portuguesa de Cardiologia (English Edition)最新文献_第6页

Applicability of Martin-Hopkins formula and comparison with Friedewald formula for estimated low-density lipoprotein cholesterol in e_COR study population e_COR研究人群低密度脂蛋白胆固醇估算的Martin-Hopkins公式的适用性及与Friedewald公式的比较

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-10-01 DOI: 10.1016/j.repce.2021.07.001

Cátia Ferrinho , Ana Catarina Alves , Mafalda Bourbon , Sequeira Duarte

{"title":"Applicability of Martin-Hopkins formula and comparison with Friedewald formula for estimated low-density lipoprotein cholesterol in e_COR study population","authors":"Cátia Ferrinho , Ana Catarina Alves , Mafalda Bourbon , Sequeira Duarte","doi":"10.1016/j.repce.2021.07.001","DOIUrl":"10.1016/j.repce.2021.07.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Low-density lipoprotein cholesterol (LDL) is essential in managing cardiovascular disease risk. Since 1972, the Friedewald formula has been used to estimate LDL concentration, although with some limitations. In 2013, Martin et al. proposed a similar but more accurate formula for calculating LDL.</p></div><div><h3>Aim</h3><p>To assess the applicability of the new formula, which we have named the Martin-Hopkins formula, in the Portuguese population and compare it with the Friedewald formula using direct LDL.</p></div><div><h3>Methods</h3><p>Cross-sectional study, including 1689 participants from the e_COR study. We applied the Martin-Hopkins and Friedewald formulas for estimated LDL (LDL-M and LDL-F). The Friedewald formula was not applied in 12 cases due to triglycerides ≥400mg/dL. Direct LDL was measured and the accepted significance level was p<0.05.</p></div><div><h3>Results</h3><p>Of the total subjects, 50.2% were male and had a median age of 51 (34) years. LDL-D was 117.0 (44.0) mg/dL, LDL-M was 114.6 (43.7) mg/dL and LDL-F was 113.8 (43.2) mg/dL. The Spearman coefficient (ρ) between LDL-M/LDL-D was 0.987 and between LDL-F/LDL-D was 0.983, p=0.001. This strong correlation was maintained in the group with diabetes (LDL-M/LDL-D ρ=0.987; LDL-F/LDL-D ρ=0.978, p=0.001) and hypertriglyceridemia (LDL-M/LDL-D ρ=0.983; LDL-F/LDL-D ρ=0.982, p=0.001). In terms of agreement, the highest value of κ=0.90 was obtained for LDL-M when LDL-D <100mg/dL.</p></div><div><h3>Conclusion</h3><p>The Martin-Hopkins formula performed well and had good applicability, showing superiority in relation to the Friedewald formula, especially for LDL-D values <100mg/dL, diabetes, and hypertriglyceridemia.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 715-724"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Beta-blockers in acute coronary syndrome patients: The concept of ‘gradient of benefit’ -受体阻滞剂在急性冠脉综合征患者中的应用:“获益梯度”的概念

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-10-01 DOI: 10.1016/j.repce.2021.10.017

Fernando Montenegro Sá , João Morais

引用次数: 0

Arterial switch operation for transposition of great arteries: Is coronary artery circulation evaluation necessary? 大动脉转位的动脉转换手术:是否有必要进行冠状动脉循环评估?

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-10-01 DOI: 10.1016/j.repce.2021.10.003

António Marinho-da-Silva

引用次数: 0

Diastolic dysfunction and type 1 diabetes: A sweet link? 舒张功能障碍与1型糖尿病:甜蜜的联系?

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-10-01 DOI: 10.1016/j.repce.2021.10.007

José Ribeiro

引用次数: 0

Consensus document on chronic coronary syndrome assessment and risk stratification in Portugal: A position paper statement from the [Portuguese Society of Cardiology’s] Working Groups on Nuclear Cardiology, Magnetic Resonance and Cardiac Computed Tomography, Echocardiography, and Exercise Physiology 关于葡萄牙慢性冠状动脉综合征评估和风险分层的共识文件:来自[葡萄牙心脏病学会]核心脏病学、磁共振和心脏计算机断层扫描、超声心动图和运动生理学工作组的立场文件声明

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-10-01 DOI: 10.1016/j.repce.2021.08.004

N. Bettencourt, Lígia Mendes, J. Fontes, P. Matos, C. Ferreira, A. Botelho, S. Carvalho, A. Durazzo, A. Faustino, R. Ladeiras-Lopes, M. Vasconcelos, C. Vieira, M. Correia, A. Ferreira, N. Ferreira, G. Pires-Morais, A. Almeida, M. Ferreira, M. Teixeira

引用次数: 0

Risk prediction for adverse events in pediatric acute myocarditis: Are we there yet? 儿童急性心肌炎不良事件的风险预测:我们做到了吗?

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-09-01 DOI: 10.1016/j.repce.2021.08.007

Soham Dasgupta

引用次数: 0

Balloon pulmonary angioplasty – welcome to chronic thromboembolic pulmonary hypertension treatment 球囊肺动脉成形术-欢迎慢性血栓栓塞性肺动脉高压治疗

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-09-01 DOI: 10.1016/j.repce.2021.08.009

Nick H. Kim

引用次数: 0

Prognostic impact of high flow nasal cannula compared to noninvasive positive-pressure ventilation in the treatment of acute pulmonary edema 高流量鼻插管与无创正压通气治疗急性肺水肿的预后影响比较

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-09-01 DOI: 10.1016/j.repce.2021.04.006

Williams Hinojosa , Carolina Iglesias , Silvio Vera , Marta Marcos , Aitor Uribarri , Itziar Gómez , Gemma Pastor

引用次数: 0

Could the unfortunate outcome of pediatric acute myocarditis be predicted? Factors contributing to a poor outcome in myocarditis 小儿急性心肌炎的不幸结局可以预测吗?导致心肌炎预后不良的因素

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-09-01 DOI: 10.1016/j.repce.2020.10.020

Stasa Krasic , Sergej Prijic , Sanja Ninic , Dejan Nesic , Bojko Bjelakovic , Gordana Petrovic , Ivana Cerovic , Vladislav Vukomanovic

{"title":"Could the unfortunate outcome of pediatric acute myocarditis be predicted? Factors contributing to a poor outcome in myocarditis","authors":"Stasa Krasic , Sergej Prijic , Sanja Ninic , Dejan Nesic , Bojko Bjelakovic , Gordana Petrovic , Ivana Cerovic , Vladislav Vukomanovic","doi":"10.1016/j.repce.2020.10.020","DOIUrl":"10.1016/j.repce.2020.10.020","url":null,"abstract":"<div><h3>Objective</h3><p>Myocarditis has spontaneous resolution in 50% of patients. Our study aimed to define risk factors for developing dilated cardiomyopathy (DCM) and death in pediatric patients with acute myocarditis (AM).</p></div><div><h3>Methods</h3><p>The retrospective cohort study included all patients with treated AM. The Mother and Child Health Institute from January 2011 to March 2019.</p></div><div><h3>Results</h3><p>In the study, 62 patients were included, 40 boys and 22 girls (11.15±5.86 years) with AM. Twelve out of sixty-two children had acute fulminant myocarditis. Four patients died in the acute phase of AM, and 11 developed DCM. Follow up was 27.14±36.52 months. Patients with poor outcome (DCM development) were under the age of seven (odds ratio [OR] 10.1; p=0.003), more likely to be girls (OR 4.6; p=0.03), and had fulminant myocarditis (OR 27.0; <0.001). An ejection fraction (EF) <55% and fractional shortening (FS) <30% increased risk of DCM 13- and 5-fold, respectively, but patients with EF between 40 and 55% remain at highest risk of developing DCM. There was a 12-fold increased risk for DCM in patients with left ventricular end-diastolic diameter Z score >2+. The receiver operator curve showed that the lactate dehydrogenase (LDH) cut-off value for developing DCM was 1780 mmol/l (sensitivity 80%, specificity 100%).</p></div><div><h3>Conclusion</h3><p>Acute fulminant myocarditis was an independent risk factor for DCM. Children with EF between 40 and 50% at admission were at highest risk of developing DCM. Lactate dehydrogenase value could be a significant prognostic value for the outcome of pediatric myocarditis.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 9","pages":"Pages 631-638"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2020.10.020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39404246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

2020 European Society of Cardiology Core Curriculum for the Cardiologist. Is it time for change in the Portuguese cardiology training program? 2020年欧洲心脏病学会心脏病专家核心课程。是时候改变葡萄牙心脏病学培训计划了吗?

Revista Portuguesa de Cardiologia (English Edition) Pub Date : 2021-09-01 DOI: 10.1016/j.repce.2021.03.010

Kevin Domingues , Lino Gonçalves , Maria João Vidigal , Felix C. Tanner , Miguel Mendes

引用次数: 0