Soraia Nicola Rodrigues , Helga Rafael Henriques , Maria Adriana Henriques
{"title":"Response to the letter from Rodrigues M and Vaz IM regarding the article “Effectiveness of a preoperative breathing exercise intervention in patients undergoing cardiac surgery: a systematic review”","authors":"Soraia Nicola Rodrigues , Helga Rafael Henriques , Maria Adriana Henriques","doi":"10.1016/j.repce.2021.10.016","DOIUrl":"10.1016/j.repce.2021.10.016","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 809-810"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2174204921003184/pdfft?md5=8da71a6c144199b3d6c421bbd188efbc&pid=1-s2.0-S2174204921003184-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39686015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In search of accurate estimates of low-density lipoprotein cholesterol levels – a better compass","authors":"António Miguel Ferreira","doi":"10.1016/j.repce.2021.10.004","DOIUrl":"10.1016/j.repce.2021.10.004","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 725-726"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2174204921002877/pdfft?md5=a6a021e632f8aeb0f65ccd1f71190a33&pid=1-s2.0-S2174204921002877-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rui Plácido , Tatiana Guimarães , David Jenkins , Nuno Cortez-Dias , Sara Couto Pereira , Paula Campos , Ana Mineiro , Nuno Lousada , Susana R. Martins , Susana Moreira , Ana Rocha Dias , Catarina Lopes Resende , Rita Vieira , Fausto J. Pinto
{"title":"Chronic thromboembolic pulmonary hypertension: Initial experience of patients undergoing pulmonary thromboendarterectomy","authors":"Rui Plácido , Tatiana Guimarães , David Jenkins , Nuno Cortez-Dias , Sara Couto Pereira , Paula Campos , Ana Mineiro , Nuno Lousada , Susana R. Martins , Susana Moreira , Ana Rocha Dias , Catarina Lopes Resende , Rita Vieira , Fausto J. Pinto","doi":"10.1016/j.repce.2021.08.002","DOIUrl":"10.1016/j.repce.2021.08.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Pulmonary endarterectomy (PEA) is a potentially curative procedure in patients with chronic thromboembolic pulmonary hypertension (CTEPH). This study reports the initial experience of a Portuguese PH center with patients undergoing PEA at an international surgical reference center.</p></div><div><h3>Methods</h3><p>Prospective observational study of consecutive CTEPH patients followed at a national PH center, who underwent PEA at an international surgical reference center between October 2015 and March 2019. Clinical, functional, laboratory, imaging and hemodynamic parameters were obtained in the 12 months preceding the surgery and repeated between four and six months after PEA.</p></div><div><h3>Results</h3><p>27 consecutive patients (59% female) with a median age of 60 (49-71) years underwent PEA. During a median follow‐up of 34 (21-48) months, there was an improvement in functional class in all patients, with only one cardiac death. From a hemodynamic perspective, there was a reduction in mean pulmonary artery pressure from 48 (42-59) mmHg to 26 (22-38) mmHg, an increase in cardiac output from 3.3 (2.9-4.0) L/min to 4.9 (4.2-5.5) L/min and a reduction in pulmonary vascular resistance from 12.1 (7.2-15.5) uW to 3.5 (2.6-5,2) uW. During the follow‐up, 44% (n=12) of patients had no PH criteria, 44% (n=12) had residual PH and 11% (n=3) had PH recurrence. There was a reduction of N‐terminal pro‐B‐type natriureticpeptide from 868 (212-1730) pg/mL to 171 (98-382) pg/mL. Rright ventricular systolic function parameters revealed an improvement in longitudinal systolic excursion and peak velocity of the plane of the tricuspid ring from 14 (13–14) mm and 9 (8–10) cm/s to 17 (16–18) mm and 13 (11-15) cm/s, respectively. Of the 26 patients with preoperative right ventricular dysfunction, 85% (n=22) recovered. The proportion of patients on specific vasodilator therapy decreased from 93% to 44% (p<0.001) and the proportion of those requiring oxygen therapy decreased from 52% to 26% (p=0.003). The six‐minute walk test distance increased by about 25% compared to the baseline and only eight patients had significant desaturation during the test.</p></div><div><h3>Conclusion</h3><p>Pulmonary endarterectomy performed at an experienced high-volume center is a safe procedure with a very favorable medium-term impact on functional, hemodynamic and right ventricular function parameters in CTEPH patients with operable disease. It is possible for PH centers without PEA differentiation to refer patients safely and effectively to an international surgical center in which air transport is necessary.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 741-752"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2174204921002488/pdfft?md5=bc22f9e037762f86c0d31d7b6b475a88&pid=1-s2.0-S2174204921002488-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The biggest right atria in the world","authors":"Edison Muñoz Ortiz , Jairo Alfonso Gándara Ricardo , Edwin Arévalo Guerrero","doi":"10.1016/j.repce.2021.10.014","DOIUrl":"10.1016/j.repce.2021.10.014","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 805-806"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2174204921003160/pdfft?md5=bab8864609901a239eb53321c3811406&pid=1-s2.0-S2174204921003160-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39686017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safety and efficacy of balloon pulmonary angioplasty in a Portuguese pulmonary hypertension expert center: A step in the right direction","authors":"Graça Castro","doi":"10.1016/j.repce.2021.10.005","DOIUrl":"10.1016/j.repce.2021.10.005","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 739-740"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2174204921002889/pdfft?md5=7ce535749f4b6381649eb7ed94526068&pid=1-s2.0-S2174204921002889-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesús Velásquez-Rodríguez , Manuel Martínez-Sellés
{"title":"Reply to letter “Beta-blockers in acute coronary syndrome patients: The concept of ‘gradient of benefit”’","authors":"Jesús Velásquez-Rodríguez , Manuel Martínez-Sellés","doi":"10.1016/j.repce.2021.10.018","DOIUrl":"10.1016/j.repce.2021.10.018","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 813-814"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2174204921003202/pdfft?md5=a8ccc7725d705a96e41c698b88acb3f8&pid=1-s2.0-S2174204921003202-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39686018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inflammation and ischemic heart disease: The next therapeutic target?","authors":"Eduardo M. Vilela , Ricardo Fontes-Carvalho","doi":"10.1016/j.repce.2021.10.010","DOIUrl":"10.1016/j.repce.2021.10.010","url":null,"abstract":"<div><p>Inflammation plays an important role in several stages of the cardiovascular continuum. In recent decades a plethora of studies have provided new data highlighting the role of inflammation in atherogenesis and atherothrombosis in two-way interactions with various cardiovascular risk factors and further influencing these dynamic processes. The concept of targeting residual inflammatory risk among individuals with ischemic heart disease (IHD) is therefore gaining increasing attention. Recently, several landmark randomized controlled trials have assessed different pharmacological approaches that may mitigate this residual risk. The results of some of these studies, such as CANTOS with canakinumab and COLCOT and LoDoCo2 with colchicine, are promising and have provided data to support this concept. Moreover, though several aspects remain to be clarified, these trials have shown the potential of modulating inflammation as a new target to reduce the risk of cardiovascular events in secondary prevention patients. In the present review, we aim to present a pragmatic overview of the complex interplay between inflammation and IHD, and to critically appraise the current evidence on this issue while presenting future perspectives on this topic of pivotal contemporary interest.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 785-796"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S217420492100310X/pdfft?md5=d2e749cd35c0a7200207836005299c41&pid=1-s2.0-S217420492100310X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39686011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susana M. Abreu , Marta António , Hugo Marques , José D.F. Martins , Fátima F. Pinto
{"title":"Acquired anomalies of the coronary arteries after arterial switch operation. Usefulness of coronary computed tomography angiography and impact on follow-up","authors":"Susana M. Abreu , Marta António , Hugo Marques , José D.F. Martins , Fátima F. Pinto","doi":"10.1016/j.repce.2020.11.027","DOIUrl":"10.1016/j.repce.2020.11.027","url":null,"abstract":"<div><h3>Introduction</h3><p>Mortality and morbidity in patients with transposition of the great arteries after an arterial switch operation depends mainly on the status of coronary perfusion. Coronary computed tomography angiography (CCTA) provides accurate information on coronary morphology, however its use in these patients is not yet routine procedure.</p></div><div><h3>Objective</h3><p>We sought to assess its accuracy to identify acquired coronary anomalies in this population, compared to conventional angiography in a subset of patients, and assess its impact on postoperative management.</p></div><div><h3>Methods</h3><p>Retrospective analysis of clinical data on transposition of the great arteries in patients who underwent CCTA between January 2013 and September 2017.</p></div><div><h3>Results</h3><p>Between January 2013 and September 2017, 18 patients underwent CCTA. Seven patients (39%) disclosed iatrogenic coronary lesions (stenosis 1; kinking 2, occlusion 1; filiform coronary 3). The exam was performed in 78% of patients due to suggestion of myocardial ischemia (symptoms or altered exams). Only 16% needed to undergo additional exams, and in four patients the CCTA result modified therapeutic management.</p><p>Conventional coronary angiography was also performed in 10 patients (55%), and in three cases, the results were discordant with underestimation or non-identification of coronary lesions on conventional angiography.</p><p>The medium radiation dose used was 2.4 mSv and no complications after CT were reported.</p></div><div><h3>Conclusion</h3><p>CCTA accurately identified iatrogenic postoperative coronary lesions and it has proven to be superior to conventional angiography in this population. It should be performed routinely in this group of patients, even in the absence of symptoms.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 10","pages":"Pages 707-712"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2174204921002853/pdfft?md5=6ed8c29eb39fad655e7206f469f852e9&pid=1-s2.0-S2174204921002853-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}