Revista Portuguesa de Cardiologia (English Edition)最新文献

{"title":"Acute myocarditis after SARS-CoV-2 vaccination in a 24-year-old man.","authors":"Paolo Cimaglia, Paolo Tolomeo, Claudio Rapezzi","doi":"10.1016/j.repc.2021.07.005","DOIUrl":"https://doi.org/10.1016/j.repc.2021.07.005","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139907272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a gender gap in national Cardiology research? Data review from the Portuguese Journal of Cardiology","authors":"Ana Teresa Timóteo","doi":"10.1016/j.repce.2020.07.016","DOIUrl":"10.1016/j.repce.2020.07.016","url":null,"abstract":"<div><p>gA ender gap is apparent in several professional areas, including in Medicine and particularly in the Cardiovascular field. We present a brief review of the subject and we analyse data from the Portuguese Journal of Cardiology regarding women authorship.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 501-504"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2020.07.016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39193653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac metastasis of primary bronchial carcinoid","authors":"Pedro Gonçalves-Teixeira ,&nbsp;Ricardo Ladeiras-Lopes ,&nbsp;Nuno Dias Ferreira","doi":"10.1016/j.repce.2021.07.023","DOIUrl":"10.1016/j.repce.2021.07.023","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 523-524"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39193658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary artery bypass grafting in a child with Kawasaki disease","authors":"Pedro Magro ,&nbsp;Nuno Carvalho ,&nbsp;Rui Anjos ,&nbsp;José Neves","doi":"10.1016/j.repce.2021.07.021","DOIUrl":"10.1016/j.repce.2021.07.021","url":null,"abstract":"<div><p>Kawasaki disease (KD) with cardiac involvement can result in the development of coronary aneurysm, stenosis or thrombosis with significant cardiovascular implications. We report the case of a 23-month-old male with a late diagnosis of KD, in whom intravenous immunoglobulin treatment was not feasible. The patient's course was assessed by routine echocardiography. At the age of five years, angiographic assessment revealed an aneurysm of the anterior descending coronary artery measuring 17 mm×7 mm involving the first diagonal branch, 90% post-aneurysmal stenosis, and an aneurysm of the right coronary artery measuring 32 mm×6 mm. Due to the critical anatomy of the anterior descending artery the revascularization method of choice was coronary artery bypass surgery with an internal mammary artery graft, under cardiopulmonary bypass. There were no significant intraoperative or postoperative complications. This confirms coronary artery bypass grafting as a reliable treatment option for patients who present with coronary sequelae from KD, even at a very young age.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 519.e1-519.e4"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39193655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of cardio-oncology clinical assessment for prevention of chemotherapy-induced cardiotoxicity","authors":"Felipa de Mello Sampayo ,&nbsp;Manuela Fiuza ,&nbsp;Fausto Pinto ,&nbsp;Joana Fontes","doi":"10.1016/j.repce.2021.07.016","DOIUrl":"10.1016/j.repce.2021.07.016","url":null,"abstract":"<div><h3>Introduction</h3><p>Cancer chemotherapy increases the risk of heart failure. This cost-effectiveness study analyzes cardio-oncology imaging assessment of left ventricular ejection fraction (LVEF) using a Portuguese healthcare payer perspective and a five-year time horizon.</p></div><div><h3>Methods</h3><p>Two cardioprotective strategies were assessed: universal cardioprotection (UCP) for all patients and cardioprotection initiated on diagnosis of LVEF-defined cardiotoxicity (EF-CTX). A Markov model, informed by the retrospective clinical course of breast cancer patients followed in a Portuguese public hospital, was developed to assess the cost-effectiveness of LVEF cardio-oncology imaging assessment. Data on transition probabilities, costs and utilities were retrieved from both the retrospective data and published literature to assess the cost-effectiveness of LVEF echocardiographic assessment. Costs and utilities of the cardioprotective strategies were assessed over a five-year range, using probabilistic sensitivity analyses.</p></div><div><h3>Results</h3><p>In the reference case of a 63-year-old breast cancer patient treated with cardioprotection initiated on diagnosis of EF-CTX, the five-year time horizon (4.22 QALYs and €2594 cost over five years) dominated UCP (3.42 QALYS and €3758 cost over five years). Under a time horizon of five years at a willingness-to-pay threshold of €22 986, over 65.7% of simulations provided additional QALYs. Monte Carlo simulation of the Markov model had no effect on the model's conclusions.</p></div><div><h3>Conclusion</h3><p>In the Portuguese public healthcare system and under specific hypotheses, from a healthcare payer perspective, EF-CTX-guided cardioprotection for patients at risk of chemotherapy-related cardiotoxicity provides more QALYs at lower cost than UCP.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 475-483"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39194690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of SARS-CoV-2 pandemic on ST-elevation myocardial infarction admissions and outcomes in a Portuguese primary percutaneous coronary intervention center: Preliminary Data","authors":"André Azul Freitas ,&nbsp;Rui Baptista ,&nbsp;Valdirene Gonçalves ,&nbsp;Cátia Ferreira ,&nbsp;James Milner ,&nbsp;Carolina Lourenço ,&nbsp;Susana Costa ,&nbsp;Fátima Franco ,&nbsp;Sílvia Monteiro ,&nbsp;Francisco Gonçalves ,&nbsp;Lino Gonçalves","doi":"10.1016/j.repce.2021.07.014","DOIUrl":"10.1016/j.repce.2021.07.014","url":null,"abstract":"<div><h3>Introduction</h3><p>Coronavirus disease (COVID-19) has led to significant changes in healthcare systems and its impact on the treatment of cardiovascular conditions, such as ST-elevation myocardial infarction (STEMI), is unknown in countries where the healthcare systems were not saturated, as was the case in Portugal. As such, we aimed to assess the effect on STEMI admissions and outcomes in Portuguese centers.</p></div><div><h3>Methods</h3><p>We conducted a single-center, observational, retrospective study including all patients admitted to our hospital due to STEMI between the date of the first SARS-CoV-2 case diagnosed in Portugal and the end of the state of emergency (March and April 2020). Patient characteristics and outcomes were assessed and compared with the same period of 2019.</p></div><div><h3>Results</h3><p>A total of 104 STEMI patients were assessed, 55 in 2019 and 49 in 2020 (-11%). There were no significant differences between groups regarding age (62±12 vs. 65±14 years, p=0.308), gender (84.8% vs. 77.6% males, p=0.295) or comorbidities. In the 2020 group, there was a significant decrease in the proportion of patients transported to the hospital in pre-hospital emergency medical transportation (38.2% vs. 20.4%, p=0.038), an increase in system delay (49 [30-110.25] vs. 140 [90-180] minutes, p=0.019), a higher Killip-Kimball class, with a decrease in class I (74.5% vs. 51%) and an increase in class III (1.8% vs. 8.2%) and IV (5.5% vs. 18.4%) (p=0.038), a greater incidence of vasoactive support (3.7% vs. 26.5%, p=0.001), invasive mechanic ventilation usage (3.6% vs. 14.3%, p=0.056), and an increase in severe left ventricular dysfunction at hospital discharge (3.6% vs. 16.3%, p=0.03). In-hospital mortality was 14.3% in the 2020 group and 7.3% in the 2019 group p=0.200).</p></div><div><h3>Conclusion</h3><p>Despite a lack of significant variation in the absolute number of STEMI admissions, there was an increase in STEMI clinical severity and significantly worse outcomes during the SARS-CoV-2 pandemic. An increase in system delay, impaired pre-hospital care and patient fear of in-hospital infection can partially justify these results and should be the target of future actions in further waves of the pandemic.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 465-471"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39194685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast-induced nephropathy: Can we better predict and prevent it?","authors":"Pedro Pinto Cardoso","doi":"10.1016/j.repce.2021.07.019","DOIUrl":"10.1016/j.repce.2021.07.019","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 499-500"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39194691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the efficacy of statins in primary and secondary prevention of atrial fibrillation","authors":"Alireza Oraii ,&nbsp;Ali Vasheghani-Farahani ,&nbsp;Saeed Oraii ,&nbsp;Pegah Roayaei ,&nbsp;Pargol Balali ,&nbsp;Farzad Masoudkabir","doi":"10.1016/j.repce.2020.11.024","DOIUrl":"10.1016/j.repce.2020.11.024","url":null,"abstract":"<div><p>Atrial fibrillation is the most common arrhythmia in adults and its prevalence is growing rapidly. It has been shown that AF is associated with increased risk of heart failure, ischemic and hemorrhagic stroke, and mortality. Hence, there is growing interest among researchers in seeking preventive and therapeutic interventions regarding AF. In recent decades, it has been suggested that statins may decrease the incidence of AF and may also decrease its recurrence after cardioversion and catheter ablation. These effects are thought to be mediated by different mechanisms such as modulating inflammation, altering the properties of transmembrane ion channels, interfering with activation of matrix metalloproteinases, and acting on endothelial function. In this article, we review and update current knowledge about the role of statins in primary and secondary prevention of AF in general and specific populations.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 509-518"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2020.11.024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39193654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of oxidant and antioxidant status for contrast-induced nephropathy after percutaneous coronary intervention for ST-segment elevation myocardial infarction","authors":"Fatih Aksoy ,&nbsp;Hasan Aydın Baş ,&nbsp;Ali Bağcı ,&nbsp;Hasan Basri Savaş","doi":"10.1016/j.repce.2021.07.018","DOIUrl":"10.1016/j.repce.2021.07.018","url":null,"abstract":"<div><h3>Background</h3><p>Contrast-induced nephropathy (CIN) is a life-threatening complication after primary percutaneous coronary intervention (p-PCI). Oxidative stress and inflammation may play an important role in the development of CIN.</p></div><div><h3>Objective</h3><p>We aimed to assess the relationship between total oxidant status, total antioxidant capacity, high-sensitivity C-reactive protein (hs-CRP), gamma-glutamyltransferase and uric acid (UA) in the development of CIN in patients presenting with ST-elevation myocardial infarction (STEMI).</p></div><div><h3>Methods</h3><p>This prospective cohort study consisted of 341 patients with STEMI. Patients were divided into two groups: those with and those without CIN. Predictors of CIN were determined by multivariate regression analyses.</p></div><div><h3>Results</h3><p>Multivariate regression analysis showed that initial glucose level, contrast media volume/glomerular filtration ratio (eGFR) ratio, hs-CRP, UA and oxidative status index were associated with the development of CIN in patients with STEMI.</p></div><div><h3>Conclusion</h3><p>The main finding of this study is that increased oxidative stress and inflammation parameters were associated with the development of CIN in patients with STEMI. Other independent predictors of CIN were contrast media volume/eGFR ratio, initial glucose level, UA and hs-CRP.</p></div>","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 489-497"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39194692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial infarction in the COVID-19 pandemic – Reperfusion therapy revisited","authors":"Jorge Ferreira","doi":"10.1016/j.repce.2021.07.015","DOIUrl":"10.1016/j.repce.2021.07.015","url":null,"abstract":"","PeriodicalId":101121,"journal":{"name":"Revista Portuguesa de Cardiologia (English Edition)","volume":"40 7","pages":"Pages 473-474"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.repce.2021.07.015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39194686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}