Revista Espa?ola de Medicina Nuclear (English Edition)最新文献

{"title":"Positive sentinel node risk in relation to oestrogen receptors in breast cancer in premenopausal and postmenopausal women","authors":"M.T. Bajén ,&nbsp;A.M. Benítez ,&nbsp;A. Domenech ,&nbsp;Y. Ricart ,&nbsp;J. Mora ,&nbsp;P. Notta ,&nbsp;D. Ramal ,&nbsp;A. Urruticoechea ,&nbsp;T. Soler ,&nbsp;J. Martín-Comin","doi":"10.1016/S1578-200X(10)70038-3","DOIUrl":"10.1016/S1578-200X(10)70038-3","url":null,"abstract":"<div><h3>Objective</h3><p>The influence of the relationship between pre- and post-menopausal stage of patients with breast cancer (BC) and the risk of sentinel lymph node (SLN) metastasis as well as the influence of oestrogen receptor (ER) status within each one of these groups were analyzed.</p></div><div><h3>Method</h3><p>A BC database with 1,388 patients was analysed. Three age groups were studied: A, elderly postmenopausal, 200 patients, ≥70 years old; B, younger postmenopausal, 89 patients, 55–69 years old; C, premenopausal, 85 patients, &lt;55 years old. In each group 2 subgroups were analyzed: positive ER and negative ER tumours. Data analysed: SLN-positive patients, non-sentinel node (NSN)-positive patients, non-surgical detections (NSD) and non disease-free (NDF) patients after a follow-up of 52 months. Statistical analysis: chi-squared test, significance: P≤0.05.</p></div><div><h3>Results</h3><p>SLN metastasis was significantly (P&lt;0.025) more common in premenopausal than in postmenopausal patients, and within those, mainly in negative ER tumours. Positive-NSN increases slightly in premenopausal patients (exclusively in negative ER tumours). NDF patients are similar in the 3 groups and in all of them it is much more frequent in negative ER tumours.</p></div><div><h3>Conclusions</h3><p>SLN metastasis varies significantly according to hormonal state and not according to age, being more frequent in premenopausal patients and mainly in ER negative tumours.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 6","pages":"Pages 289-292"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70038-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75131056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative salivary gland scintigraphy in head and neck cancer patients following radiotherapy","authors":"A. Jiménez-Heffernan ,&nbsp;J. Gómez-Millán ,&nbsp;E. Sánchez De Mora ,&nbsp;J. Delgado Moreno ,&nbsp;M.M. Delgado Gil ,&nbsp;C. Salgado ,&nbsp;P. Contreras Puertas ,&nbsp;M.C. Bermúdez Morales ,&nbsp;J. López ,&nbsp;J. Paz Expósito","doi":"10.1016/S1578-200X(10)70048-6","DOIUrl":"10.1016/S1578-200X(10)70048-6","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the role of quantitative salivary gland scintigraphy (SGS) in the detection of functional impairment of salivary glands in patients with head and neck cancer treated with radiotherapy (RT).</p></div><div><h3>Material and methods</h3><p>We studied 19 patients (17 men), mean age 62.4 years (44–75). Three studies were performed to each patient: baseline, 3 and 18 months after RT. SGS was acquired for 25 minutes following injection of 3.7<!--> <!-->MBq/kg of ^99mTc-pertechnetate with lemon juice at the end of minute 15.</p><p>Excretion fraction (EF), counts per minute/pixel/MBq (CMPM) and uptake percentage were obtained from time-activity curves from ROIs placed over parotid (PG) and submandibular glands (SMG) and related to the doses received by the PG.</p></div><div><h3>Results</h3><p>EF showed a significant reduction from the baseline to the 3 months study (p<!--> <!-->&lt;<!--> <!-->0.001) for the PG and SMG and from the baseline to the 18 months study for the SMG (p<!--> <!-->&lt;<!--> <!-->0.001). A significant improvement of EF was seen from the 3 months to the 18 months study for the PG (p<!--> <!-->&lt;<!--> <!-->0.05).</p><p>CMPM did not change significantly from the baseline to the 3 months and 18 months studies for the PG and showed a significant reduction (p<!--> <!-->&lt;<!--> <!-->0.01) for the SMG from the baseline to 18 months study. The uptake percentage did not change significantly between studies. A moderate association was observed between the doses to PG and the 3<!--> <!-->m study parameters.</p></div><div><h3>Conclusions</h3><p>EF was more sensitive than uptake in assessing post-RT impairment of salivary function. In addition, it reflected functional recovery of parotid glands over time.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 4","pages":"Pages 165-171"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70048-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78784363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of PET-CT on radiotherapy planning of head and neck cancer. Our initial experience","authors":"M.E. Bellón Guardia ,&nbsp;L. Pérez Romasanta ,&nbsp;A.M. García Vicente ,&nbsp;M.P. Talavera Rubio ,&nbsp;A. Palomar Muñoz ,&nbsp;B. González García ,&nbsp;V.M. Poblete García ,&nbsp;A. Soriano Castrejón","doi":"10.1016/S1578-200X(10)70047-4","DOIUrl":"10.1016/S1578-200X(10)70047-4","url":null,"abstract":"<div><h3>Objective</h3><p>To describe the methods used for the incorporation of FDG-PET-CT on radiotherapy planning of patients with head and neck cancer and also to evaluate the impact of FDG-PET-CT on staging and tumor volume definition.</p></div><div><h3>Material and methods</h3><p>A prospective study in which 20 patients with head and neck tumor submitted for radiotherapy treatment were included. All underwent a whole body PET- CT (GE DSTE 16) for staging and restaging, also acquiring an additional 3<!--> <!-->h delayed PET image with diagnostic CT parameters for planning. A CT scan with diagnostic protocol, tabletop available for radiotherapy treatment and the same personalized head-shoulder mask were used in the latter. Lymph node involvement and/or distant involvement were evaluated, considering the changes in staging. We also evaluated the differences in volumes obtained between the different techniques. The threshold value used for delineating PET gross tumor volume (GTV) was empirically established and ranged from 20–40% of the maximum SUV.</p></div><div><h3>Results</h3><p>Radiotherapy planning was performed with PET-CT in 20 patients between October 2007 to September 2008. A total of 29 lesions (18 primary lesions because 2 patients were excluded as no tumor was observed on the PET CT images, and 11 nodes). The most frequent location was oropharynx (5 patients). Mean maxSUV of the 29 lesions was 14.4 (range 5.0 and 26.4). No statistically significant differences were found between the GTV PET and CT GTV (mean 21.9<!--> <!-->cm³ and 19.3<!--> <!-->cm³, respectively). PET-CT modified the staging in 20% of the patients, with a diagnostic and therapeutic impact of 50 and 25%, respectively.</p></div><div><h3>Conclusion</h3><p>The incorporation of PET-CT in routine radiotherapy planning is a promising technique that requires close collaboration between the nuclear medicine and radiotherapy oncology departments. PET-CT achieves better staging in patients and has a significant diagnostic and therapeutic impact. The use of the hybrid technique avoids problems arising from co-registry as well as a second examination for planning with the consequent advantage for the patient. Nonetheless, more prospective and randomized studies with pathology specimens are needed to evaluate the real impact in the tumor volume definition.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 4","pages":"Pages 157-164"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70047-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82776240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notification of an adverse effect to human albumin 99MTc-nanocolloid","authors":"A. Cotrina-Monroy,&nbsp;J.A. Perez-Iruela,&nbsp;A. Lopez-López,&nbsp;R. De Juan,&nbsp;M.L. Rodríguez-Torras,&nbsp;A. Gómez Embuena","doi":"10.1016/S1578-200X(10)70042-5","DOIUrl":"10.1016/S1578-200X(10)70042-5","url":null,"abstract":"<div><p>Allergic reactions to albumin nanocolloid (NA) are rare. Most of them are not potentially serious and in some cases treatment with antihistaminics may be needed. We present a case of a patient with grade II right breast ductal carcinoma, in whom a lymphoscintigraphy was performed for sentinel lymph node detection. She had a type I hypersensitivity reaction following the administration of ^99mTc-albumin nanocolloid, which abated spontaneously without subsequent sequels.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 6","pages":"Pages 308-309"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70042-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83436242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peritoneo-scrotal communication: demonstration by 99mTc nanocoloid scintigraphy","authors":"M. Vidal ,&nbsp;D. Carrera ,&nbsp;B. Luján ,&nbsp;L. Fernández ,&nbsp;L. Quintero ,&nbsp;C. Vírgala","doi":"10.1016/S1578-200X(10)70016-4","DOIUrl":"https://doi.org/10.1016/S1578-200X(10)70016-4","url":null,"abstract":"","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 2","pages":"Pages 96-97"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70016-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137401137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colon adenocarcinoma and pharyngeal carcinoma incidentally detected by 18F-FDG PET in a patient diagnosed with lung cancer","authors":"L. Caballero Gullón,&nbsp;I. Borrego Dorado,&nbsp;R. Vázquez Albertino","doi":"10.1016/S1578-200X(10)70004-8","DOIUrl":"10.1016/S1578-200X(10)70004-8","url":null,"abstract":"<div><p>It is not uncommon to find two or more tumors in the same patient, usually based on similar etiologic factors or the use of radiotherapy and/or chemotherapy and this may occur quite often in the case of lung cancer. Positron emission tomography with ¹⁸F-FDG (PET-FDG) is widely used for the diagnosis and treatment of cancer patients and is especially useful in patients with solitary pulmonary nodule, bronchogenic carcinoma, head and neck cancer, colon cancer, tumors of unknown origin, lymphomas, among others. Likewise, this approach has also been demonstrated to detect previously unsuspected second or third primary tumors.</p><p>We report a clinical case in which two synchronous cancers were incidentally detected in a 73-year-old patient diagnosed with lung cancer and referred for PET-FDG study.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 1","pages":"Pages 29-31"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70004-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75247013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Descending thoracic and abdominal aortic aneurysm in perfusion ventilation scintigraphy. An incidental finding","authors":"F.J. Hidalgo Ramos ,&nbsp;P. Contreras Puertas ,&nbsp;F.R. Maza Muret ,&nbsp;M. Portero De la Torre ,&nbsp;R. Del Real Núñez ,&nbsp;J.M. Latre Romero","doi":"10.1016/S1578-200X(10)70036-X","DOIUrl":"10.1016/S1578-200X(10)70036-X","url":null,"abstract":"","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 5","pages":"Pages 270-271"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70036-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73627306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibrous dysplasia of the bone. Contribution of Nuclear Medicine in the Diagnosis of Suspicion of Sarcomatous Degeneration","authors":"A. Santiago Chinchilla ,&nbsp;C. Ramos Font ,&nbsp;M. Tello Moreno ,&nbsp;A.C. Rebollo Aguirre ,&nbsp;M. Navarro-Pelayo Láinez ,&nbsp;M. Gallego Peinado ,&nbsp;J.M. Llamas Elvira","doi":"10.1016/S1578-200X(10)70049-8","DOIUrl":"10.1016/S1578-200X(10)70049-8","url":null,"abstract":"<div><p>Fibrous dysplasia is a relative frequent benign bone disease in which there is a maturation disorder of the bone-forming mesenchyma where the lamellar bone marrow is replaced with abnormal fibrous tissue. Its diagnosis is often an accidental finding when X-ray studies or bone scans are performed for other reasons since it is usually asymptomatic. There may be complications such as deformities, pathological fractures and exceptionally malignant transformation. The differential diagnosis between malignancy and FD can be complicated and lead to late diagnosis when sarcomatous degeneration already exists. In this context, ¹⁸F-fluorodeoxyglucose positron emission tomography (FDG-PET) may be useful in the monitoring of this condition. We present two cases of patients diagnosed with FD with suspicion of malignization of their bone lesions who were referred for complementary imaging studies of Nuclear Medicine.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 4","pages":"Pages 172-176"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70049-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84406024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental detection of a papillary thyroid cancer by 18F-FDG PET-CT study in a patient with metastatic colorectal cancer","authors":"J. Banzo ,&nbsp;M.A. Ubieto ,&nbsp;J. Villalta ,&nbsp;P. Razola ,&nbsp;E. Prats ,&nbsp;A. Andrés","doi":"10.1016/S1578-200X(10)70044-9","DOIUrl":"10.1016/S1578-200X(10)70044-9","url":null,"abstract":"","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 6","pages":"Pages 312-313"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70044-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79432159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nodular goiter: a scintigraphic finding in myocardial perfusion SPECT","authors":"B. Luján,&nbsp;R. Siurana,&nbsp;D. Carrera,&nbsp;V. Izquierdo,&nbsp;L. Quintero,&nbsp;C. Virgala","doi":"10.1016/S1578-200X(10)70034-6","DOIUrl":"10.1016/S1578-200X(10)70034-6","url":null,"abstract":"","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 5","pages":"Pages 266-267"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70034-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81209486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}