{"title":"Prognostic value of normal myocardial perfusion scintigraphy with 201Tl in post-acute myocardial infarction","authors":"F.G. Gallardo , M.V. Gómez , I. Terol","doi":"10.1016/S1578-200X(11)70011-0","DOIUrl":"https://doi.org/10.1016/S1578-200X(11)70011-0","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this work has been to determine the prognostic value of normal thallium-201 myocardial perfusion scintigraphy (MPS) in patients who had suffered myocardial infarction in the three months prior to the examination.</p></div><div><h3>Material and methods</h3><p>A stress test followed by <sup>201</sup>Tl Gated SPECT was performed. A follow-up was made of 63 patients with normal perfusion scintigraphy. According to the MPS results, the patients were divided into 2 groups. Group I (n<!--> <!-->=<!--> <!-->63; 57% males, age 65<!--> <!-->±<!--> <!-->12), patients with normal MPS, and group II (n<!--> <!-->=<!--> <!-->60; 81% males, age 64±10), patients with abnormal MPS. The appearance of a new infarction or cardiac death occurring during this period (63±3 months) was analyzed. The appearance of events was related with the cardiovascular risk factors, perfusion study and ventricular function.</p></div><div><h3>Results</h3><p>Five events occurred in group I in 4 patients: 3 new infarctions and 2 cardiac deaths. In group II, there were 18 events in 14 patients: 8 new infarctions and 10 cardiac deaths (p<0.0001). The events were related with age, time from MPS, diabetes, size of perfusion defect and post stress ventricular ejection fraction. Mean survival en group I was 108 months (103-112) and in group II 97 (88-107) (p=0.01).</p></div><div><h3>Conclusion</h3><p>Patients with normal MPS had fewer major events than patients with abnormal MPS. The size of MPS has been related with the appearance of events. A depressed post-stress left ventricular ejection fraction has a poor prognosis.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 2","pages":"Pages 83-87"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70011-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91598063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Milà López , M. Fraile López-Amor , J. Bechini Bernard , V. Vallejos Arroyo , I. Guasch Arriaga , J. Riba Jofré
{"title":"Findings of lung ventilation-perfusion SPECT-CT study in a case of pulmonary thromboembolism in a child","authors":"M. Milà López , M. Fraile López-Amor , J. Bechini Bernard , V. Vallejos Arroyo , I. Guasch Arriaga , J. Riba Jofré","doi":"10.1016/S1578-200X(10)70024-3","DOIUrl":"10.1016/S1578-200X(10)70024-3","url":null,"abstract":"","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 142-143"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70024-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74246239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Sánchez-Sánchez, A. Rodríguez-Fernández, Á. Ramírez-Navarro, M. Gómez-Río, C. Ramos-Font, J.M. Llamas-Elvira
{"title":"PET/CT: Focal lung uptake of 18F-fluordeoxyglucose on PET but no structural alterations on CT","authors":"R. Sánchez-Sánchez, A. Rodríguez-Fernández, Á. Ramírez-Navarro, M. Gómez-Río, C. Ramos-Font, J.M. Llamas-Elvira","doi":"10.1016/S1578-200X(10)70021-8","DOIUrl":"10.1016/S1578-200X(10)70021-8","url":null,"abstract":"<div><p>The combination of positron emission tomography (PET) and computed tomography (CT) in a single device (PET/CT) provides a powerful diagnostic tool opening new horizons for imaging diagnosis.</p><p>In order to correctly interpret PET/CT studies, knowledge of the biodistribution of <sup>18</sup>F-fluorodeoxyglucose (FDG), the physiological variants as well as the pitfalls, including the artefacts which may be found is necessary. We report four cases performed during the follow up diagnosis of an oncology study performed with <sup>18</sup>F-FDG-PET/CT. This study showed focal uptake in the lung parenchyma in the PET study in all the cases, with no structural lesions being found on CT scan. Radiotracer extravasation in three of these patients and a recent change in the injection protocol used suggest that an artefact was responsible for these discrepancies.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 131-134"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70021-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79602537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Orcajo Rincón , J.C. Alonso Farto , A. Rotger Regi , D. Zamudio Rodríguez , V. Pérez Aradas
{"title":"Usefulness of nonattenuation-corrected positron emission tomography image in a patient with hepatocarcinoma treated with chemoembolization","authors":"J. Orcajo Rincón , J.C. Alonso Farto , A. Rotger Regi , D. Zamudio Rodríguez , V. Pérez Aradas","doi":"10.1016/S1578-200X(10)70025-5","DOIUrl":"10.1016/S1578-200X(10)70025-5","url":null,"abstract":"","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 144-145"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70025-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76076169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Luján , D. Carrera , J. Picas , V. Izquierdo , R. Siurana , L. Quintero , C. Martínez de Vírgala
{"title":"Detection of contralateral axillary sentinel lymph node by lymphoscintigraphy in breast cancer: Prognostic implications","authors":"B. Luján , D. Carrera , J. Picas , V. Izquierdo , R. Siurana , L. Quintero , C. Martínez de Vírgala","doi":"10.1016/S1578-200X(10)70022-X","DOIUrl":"10.1016/S1578-200X(10)70022-X","url":null,"abstract":"<div><p>The role of nuclear medicine in the detection of sentinel lymph nodes (SLNs) in primary breast cancer is very useful to determine regional lymphatic drainage from the affected breast, mainly its anatomical and/or tumoral individual variability and to determine the initial tumor stage.</p><p>We present the case of an infiltrating ductal carcinoma of the breast (T2) in the junction of the inner quadrants of the right breast studied by lymphoscintigraphy and gamma probe detection. Three nonmetastatic sentinel lymph nodes were found with the selective lymphadenectomy: two in the ipsilateral axilla and one in the contralateral axilla.</p><p>The lymphoscintigraphic finding of the axillary sentinel lymph node contralateral to the affected breast demonstrates the individual anatomical variability which may be found in mammary drainage and emphasizes the importance of nuclear medicine imaging techniques in the detection of such nodes, generating new prognostic approaches with impact on therapeutic measures and patient follow-up.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 135-137"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70022-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86314492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Quirico Rodríguez , I. Casáns Tormo , M.C. Redal Peña , V. Lopez Castillo
{"title":"The importance of bone scintigraphy in the diagnosis of sapho syndrome","authors":"M. Quirico Rodríguez , I. Casáns Tormo , M.C. Redal Peña , V. Lopez Castillo","doi":"10.1016/S1578-200X(10)70020-6","DOIUrl":"10.1016/S1578-200X(10)70020-6","url":null,"abstract":"<div><p>The acronym SAPHO corresponds to a group of benign conditions that combine osteoarticular and skin involvement, with the diagnosis mainly being clinical and supported by imaging findings. Bone scintigraphy has a relevant role in this syndrome due to its sensitivity and early detection ability. We present 8 patients with SAPHO syndrome who presented with skin manifestations. All had palmoplantar pustulosis, either of recent onset or outbreak evolution. Some had associated osteoarticular pain in the shoulders, sternum, lumbar area or limbs. Bone scintigraphy with Tc-99m-diphosphonate showed pathological findings in all the patients, detecting sternoclavicular joint damage, which was the most frequent involvement in 7 patients, as well as in other less usual localizations.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 127-130"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70020-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81460500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.M. Cordero García , M. Delgado Portela , A.M. García Vicente , J.P. Pilkington Woll , M.A. Palomar Muñoz , V.M. Poblete García , M.E. Bellón Guardia , R. Pardo García , L. Rabadán Ruiz , A.M. Soriano Castrejón
{"title":"Micrometastasis in the sentinel node and axillary lymph node macrometastasis in breast cancer","authors":"J.M. Cordero García , M. Delgado Portela , A.M. García Vicente , J.P. Pilkington Woll , M.A. Palomar Muñoz , V.M. Poblete García , M.E. Bellón Guardia , R. Pardo García , L. Rabadán Ruiz , A.M. Soriano Castrejón","doi":"10.1016/S1578-200X(10)70019-X","DOIUrl":"10.1016/S1578-200X(10)70019-X","url":null,"abstract":"<div><h3>Aim</h3><p>The study of the sentinel node has made it possible to obtain more comprehensive knowledge about the extent of axillary involvement in breast cancer. It has also decreased the surgical morbidity associated to the surgical examination of the axilla. The systematic use of immunohistochemical staining and molecular biology techniques improves the ability to detect the presence of micrometastasis or isolated tumor cells in a significant number of cases when this is the only sign of the lymph node extension of the disease. The possibility of avoiding complete axillary lymphadenectomy in those patients who are only affected by micrometastasis is proposed because of the low incidence of further involvement of the remaining lymph nodes.</p></div><div><h3>Material and method</h3><p>159 patients diagnosed of stage T1 or T2 breast cancer, in which the sentinel node had been identified by scintigraphy and intraoperative localization, were included in the study. Complete axillary lymphadenectomy was performed when micro- or macrometastases were found in the sentinel node, in order to determine the degree of axillary involvement.</p></div><div><h3>Results</h3><p>A total of 40 patients (25%) showed infiltration of the sentinel node. This infiltration was only by micrometastasis in 17 of them (10.7%). Of these 17 patients, only 2 (11.8%) showed macrometastasis in the lymphadenectomy. In the remaining subjects, the final staging reached after the sentinel node study was not modified.</p></div><div><h3>Conclusion</h3><p>It is possible to speculate that, in the future, axillary dissection can be avoided in those patients diagnosed of micrometastasis in the sentinel node, pending the conclusions of the on-going multicenter studies.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 122-126"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70019-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81639545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Palomar Muñoz , A.M. García Vicente , M.P. Talavera Rubio , J.P. Pilkington Woll , V.M. Poblete García , M.E. Bellón Guardia , A. León Martín , J.M. Cordero García , A. Soriano Castrejón
{"title":"Diagnostic and therapeutic impact of 18F-FDG-PET/CT in patients with suspected breast cancer recurrence","authors":"A. Palomar Muñoz , A.M. García Vicente , M.P. Talavera Rubio , J.P. Pilkington Woll , V.M. Poblete García , M.E. Bellón Guardia , A. León Martín , J.M. Cordero García , A. Soriano Castrejón","doi":"10.1016/S1578-200X(10)70017-6","DOIUrl":"10.1016/S1578-200X(10)70017-6","url":null,"abstract":"<div><p>Breast cancer is a tumor with high prevalence in our environment. Thus, it is essential to make an early diagnosis in both the primary disease and its recurrence, given the high mortality of the cases with the advanced disease. Our study has aimed to evaluate the impact of <sup>18</sup>F-FDG-PET/CT in patients with suspected breast cancer recurrence and their therapeutic management.</p><p>This study analyzed the PET/CT of 70 patients with a background of breast cancer and suspicion of recurrence, either because of elevation of tumor markers (n=28), doubtful findings on other imaging techniques (n=56) and/or suspicious symptoms (n=1).</p><p>All the patients underwent a standard FDG-PET study acquired in combination with low-dose CT.</p><p>The studies were considered pathological in 34 of the 70 patients, with 29 true positive, 32 true negative, 5 false positive and 4 false negative results. The final diagnosis was established either by histopathologic confirmation (n=17), other imaging techniques (n=26) and/or clinical radiological follow-up (n=27, mean 12.7 months). The sensitivity, specificity, positive predictive value and negative predictive values obtained were 87.8%, 86.4%, 85.2% and 88.8%, respectively. Therapeutic management was modified in 41% of the patients.</p><p>In conclusion, PET/CT is a technique with high diagnostic yield in patients with suspected breast cancer recurrence.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 100-108"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70017-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73431211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.C. Pujades Claumarchirant, J.F. Martí Vidal, C. Olivas Arroyo, P. Bello Arqués, A. Mateo Navarro
{"title":"Application of ICRP-103 in the calculation of effective dose associated to nuclear medicine tests","authors":"M.C. Pujades Claumarchirant, J.F. Martí Vidal, C. Olivas Arroyo, P. Bello Arqués, A. Mateo Navarro","doi":"10.1016/S1578-200X(10)70018-8","DOIUrl":"10.1016/S1578-200X(10)70018-8","url":null,"abstract":"<div><h3>Objective</h3><p>Re-evaluate the effective dose (E) of typical nuclear medicine procedures using the new ICRP-103 weighting factors and the latest dosimetry data and relate E with Background Equivalent Radiation Time (BERT).</p></div><div><h3>Material and methods</h3><p>Effective dose associated with radiopharmaceuticals and nuclear medicine procedures has been calculated for the following ages: adult, 15, 10, 5 and 1 year. Dosimetry data have been extracted from ICRP-106, ICRP-80, ICRP-53 and/or manufacturer's brochure.</p></div><div><h3>Results</h3><p>The relationship of the data of effective dose associated with radiopharmaceuticals and explorations is shown. The new tissue weighting factors result in a decreased value of the effective dose, except in cases that particularly affect the breast, in which it increases. The effective dose associated with nuclear medicine procedures is in the range 0.1–60 mSv. BERT ranges from a few days to 20 years. The effective dose associated to tests in children is generally higher than the effective dose for an adult.</p></div><div><h3>Conclusions</h3><p>The results shown in this paper are an updated collection of effective dose values for commonly used radiopharmaceuticals in nuclear medicine. Expressing the effective dose equivalent time in units of natural radiation helps to explain issues associated with radiation exposure to patients and healthcare personnel.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"29 3","pages":"Pages 114-121"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(10)70018-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82913777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}