D. Boj Carceller , P. Liévano Segundo , P. Navarro Beltrán , A. Sanz París , P. de Castro Hernández , M. Monreal Villanueva , D. Abós Olivares
{"title":"Short-term results of treatment with 131I in patients with multinodular goiter: effect of the associated degree of hyperthyroidism and other variables","authors":"D. Boj Carceller , P. Liévano Segundo , P. Navarro Beltrán , A. Sanz París , P. de Castro Hernández , M. Monreal Villanueva , D. Abós Olivares","doi":"10.1016/S1578-200X(11)70021-3","DOIUrl":"10.1016/S1578-200X(11)70021-3","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the effectiveness of radioactive iodine (RAI) therapy and the incidence of hypothyroidism post RAI in patients with subclinical hyperthyroidism or clinical hyperthyroidism with Multinodular Goiter (MNG).</p></div><div><h3>Methods</h3><p>A retrospective study of 69 consecutive patients treated with <sup>131</sup>I for MNG during the year 2008 observed for six months. All patients received a single fixed dose of 16 mCi (592<!--> <!-->MBq) weighted by the gland size. They were categorized into two groups: subclinical hyperthyroidism or clinical hyperthyroidism. We compared the success rate and the incidence of hypothyroidism.</p></div><div><h3>Results</h3><p>The thyroid dysfunction was corrected in 82.09% of the patients. Success rate was 100% in the clinical hyperthyroidism group and 78.13% in the subclinical hyperthyroidism group (P<!--> <!-->=<!--> <!-->0.105). The overall incidence of hypothyroidism was 16.42%; 25.00% of patients with clinical hyperthyroidism and 14.55% with subclinical hyperthyroidism developed this secondary effect (P<!--> <!-->=<!--> <!-->0.400). No statistically significant differences were found in the success rate in the incidence of hypothyroidism when the results were analyzed according to the thyrotropin decrease in patients with subclinical hyperthyroidism. Seven patients had positive anti-thyroid peroxidase antibodies (anti-TPO) before therapy. The incidence of hypothyroidism was significantly higher in them (57.14% vs 11.67%; P<!--> <!-->=<!--> <!-->0.011). Cardiac arrhythmias were four times more frequent in patients with clinical hyperthyroidism. Previous treatment with thiamazol positively affected the outcome.</p></div><div><h3>Conclusions</h3><p>A single fixed weighted dose of <sup>131</sup>I is highly effective and safe for the control of clinical and subclinical hyperthyroidism due to MNG. Patients with anti-TPO antibodies may have a high risk of developing post-iodine hypothyroidism.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 3","pages":"Pages 156-161"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70021-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84431419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Andrés, E. Prats, A. Santapau, L. Tardín, P. Razola, A. Parra, E.F. Rambalde, J. Banzo
{"title":"Intramammary sentinel lymph node preoperative identification with SPECT/CT in a patient with breast cancer. Clinical meaning and relevance","authors":"A. Andrés, E. Prats, A. Santapau, L. Tardín, P. Razola, A. Parra, E.F. Rambalde, J. Banzo","doi":"10.1016/S1578-200X(11)70014-6","DOIUrl":"10.1016/S1578-200X(11)70014-6","url":null,"abstract":"<div><p>We present the case of a patient with breast cancer who underwent selective sentinel lymph node biopsy. An intramammary sentinel lymph node was identified with SPECT/CT in the preoperative lymphoscintigraphy. We describe our diagnostic and therapeutic procedure regarding this finding and the literature review to evaluate the clinical significance of their identification and metastases, especially in regards to more appropriate axillary management. Further studies with more statistical significance are necessary to elucidate the most suitable attitude when an intramammary sentinel lymph node is identified with the lymphoscintigraphy.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 2","pages":"Pages 101-103"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70014-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75502484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.L. Vercher-Conejero , P. Bello-Arqués , L. Pelegrí-Martínez , I. Hervás-Benito , J.L. Loaiza-Góngora , M. Falgas-Lacueva , C. Ruiz-Llorca , R. Pérez-Velasco , A. Mateo-Navarro
{"title":"Abdominal splenosis: An often underdiagnosed entity","authors":"J.L. Vercher-Conejero , P. Bello-Arqués , L. Pelegrí-Martínez , I. Hervás-Benito , J.L. Loaiza-Góngora , M. Falgas-Lacueva , C. Ruiz-Llorca , R. Pérez-Velasco , A. Mateo-Navarro","doi":"10.1016/S1578-200X(11)70013-4","DOIUrl":"https://doi.org/10.1016/S1578-200X(11)70013-4","url":null,"abstract":"<div><p>Splenosis is defined as the heterotopic autotransplantation of splenic tissue because of a ruptured spleen due to trauma or surgery. It is a benign and incidental finding, although imaging tests may sometimes orient toward malignancy simulating renal tumors, abdominal lymphomas, endometriosis, among other. We report the case of a 42-year old male in whom a MRI was performed after a study due to abdominal pain. Multiple enlarged lymph nodes were observed in the abdomen, suggestive of lymphoproliferative disease. As an important background, splenectomy was carried out due to abdominal trauma at age 9. After several studies, it was decided to perform a <sup>99m</sup>Tc-labeled heat-damaged red blood cell scintigraphy that showed multiple pathological deposits distributed throughout the abdomen, and even the pelvis, being consistent with splenosis.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 2","pages":"Pages 97-100"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70013-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91598065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synovial chondromatosis with involvement of both knees. Findings on bone scintigraphy","authors":"L. Ayllón","doi":"10.1016/S1578-200X(11)70007-9","DOIUrl":"10.1016/S1578-200X(11)70007-9","url":null,"abstract":"","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 1","pages":"Page 38"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70007-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85494047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.R. García, M. Soler, S. Fuertes, E. Riera, A. Moreno, F. Lomeña, I. Carrio
{"title":"Incidence of focal myocardial 18F-FDG uptake and correlation with coronary calcifications by PET/CT","authors":"J.R. García, M. Soler, S. Fuertes, E. Riera, A. Moreno, F. Lomeña, I. Carrio","doi":"10.1016/S1578-200X(11)70002-X","DOIUrl":"10.1016/S1578-200X(11)70002-X","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the incidence of <sup>18</sup>F-FDG focal uptake in the myocardium as well as its correlation with coronary vessel calcifications.</p></div><div><h3>Material and methods</h3><p>A total of 130 patients who underwent an oncological PET/CT study were reviewed retrospectively. Sixty-five had undergone a myocardial perfusion study because of clinical suspicion of coronary artery disease (group 1). There were no significant differences in age and gender regarding another group of the same series (n = 65; group 2). Focal myocardial <sup>18</sup>F-FDG uptake and the presence of coronary vessel calcifications were identified by 2 independent observers.</p></div><div><h3>Results</h3><p>Group 1: in 18 out of 65 patients (28%) focal myocardial <sup>18</sup>F-FDG uptake was identified (5 had 2 foci; total: 23 foci). In 43 out of 65 studies (66%), calcification was identified in the coronary vessels. Group 2: in 6 out of 65 patients (9%) focal myocardial <sup>18</sup>F-FDG uptake was identified (1 had 2 foci; total: 7 foci). In 17 out of 65 studies (26%), calcification was identified in the coronary vessels.</p><p>Comparative analysis: focal myocardial <sup>18</sup>F-FDG uptake and coronary vessel calcifications were more frequent in the group 1 patients (p < 0.01).</p><p>There was no correlation between the presence of coronary vessel calcifications and focal myocardial <sup>18</sup> F-FDG uptake in individual patients in both groups (group 1: p = 0.7; group 2: p = 0.163).</p></div><div><h3>Conclusions</h3><p>PET/CT allows simultaneous assessment of focal myocardial <sup>18</sup>F-FDG uptake and myocardial vessel calcifications. Patients with clinical suspicion of coronary artery disease have a higher incidence of focal myocardial <sup>18</sup>F-FDG uptake and coronary calcifications. However, <sup>18</sup>F-FDG focal uptake is often observed in sites remote from those with calcification.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 1","pages":"Pages 8-13"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70002-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78663319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.J. Carrero Lérida , M.C. Mariscal Cerrato , C. Dávila Arias , A. López Ruiz , J. Caballero Güeto
{"title":"Transient apical dysfunction syndrome (Tako-Tsubo) simulating acute myocardial infarction","authors":"M.J. Carrero Lérida , M.C. Mariscal Cerrato , C. Dávila Arias , A. López Ruiz , J. Caballero Güeto","doi":"10.1016/S1578-200X(11)70016-X","DOIUrl":"10.1016/S1578-200X(11)70016-X","url":null,"abstract":"<div><p>Transient apical dysfunction syndrome (TADS) is frequently misdiagnosed as an acute coronary syndrome (ACS). It is characterized by electrocardiographic alterations and elevated myocardial necrosis markers, accompanied by hypokinesia, akinesia or anteroapical dyskinesia, in absence of significant coronary disorders. It generally resolves in days or weeks with individualized support measures. We present the case of a female patient referred to our service for a myocardial perfusion imaging study due to a history suggestive of an acute coronary syndrome after a stressful event.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 2","pages":"Pages 107-111"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70016-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83566631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Portilla-Quattrociocchi, I. Banzo, I. Martínez-Rodríguez, R. Quirce, J. Jiménez-Bonilla, M. de Arcocha Torres, P. Medina-Quiroz, R. del Castillo, A. Rubio-Vassallo, J.M. Carril
{"title":"Evaluation of bone scintigraphy and 18F-FDG PET/CT in bone metastases of lung cancer patients","authors":"H. Portilla-Quattrociocchi, I. Banzo, I. Martínez-Rodríguez, R. Quirce, J. Jiménez-Bonilla, M. de Arcocha Torres, P. Medina-Quiroz, R. del Castillo, A. Rubio-Vassallo, J.M. Carril","doi":"10.1016/S1578-200X(11)70001-8","DOIUrl":"10.1016/S1578-200X(11)70001-8","url":null,"abstract":"<div><h3>Objective</h3><p>To compare the bone scintigraphy (BS) findings and PET/CT scintigraphy with FDG (FDG PET/CT) in the detection of bone metastases in lung cancer.</p></div><div><h3>Material and methods</h3><p>We studied 32 patients with lung cancer who underwent FDG PET/CT and BS in a period of 15.9 ± 18.6 days. The results of both techniques were compared with the histology, where available, radiological structural techniques and the clinical follow-up. In 30 patients, a definitive diagnosis was reached with the scintigraphic findings. No final diagnosis was obtained in 2 patients.</p></div><div><h3>Results</h3><p>BS was positive in 25/30 patients (83.3%) and negative in 5 patients. FDG PET/CT was positive in 21/30 patients (70%) and negative in 9. The BS and the FDG PET/CT were positive in 19/30 patients (63.3%) for the detection of bone metastases. In 6/19, both techniques showed the same number of bone lesions. In 10/19, FDG PET/CT showed a greater number of bone metastases than BS. In 3/19 patients, BS showed more lesions than FDG PET/CT and in 2/30 patients (6.6%), the BS was normal and the FDG PET/CT showed bone lesions which were confirmed as metastasis. In 6/30 patients (20%), the FDG PET/CT was negative and the BS was positive. BS and FDG PET/CT scan were normal in 3/30 patients (10%).</p></div><div><h3>Conclusions</h3><p>In patients with lung cancer, FDG PET/CT scan detected more metastatic bone lesions than BS. It also identified bone metastasis in negative BS. In our experience, when the BS was positive and the FDG PET/CT scan was negative, the lesions observed were mostly related with degenerative bone conditions and bone fractures. In the clinical practice, the FDG PET/CT and BS have a complementary role for the assessment of bone status in lung cancer patients.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":"30 1","pages":"Pages 2-7"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70001-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123122274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}