J.R. García, M. Soler, S. Fuertes, E. Riera, A. Moreno, F. Lomeña, I. Carrio
{"title":"局灶性心肌18F-FDG摄取的发生率及其与冠状动脉钙化的相关性","authors":"J.R. García, M. Soler, S. Fuertes, E. Riera, A. Moreno, F. Lomeña, I. Carrio","doi":"10.1016/S1578-200X(11)70002-X","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the incidence of <sup>18</sup>F-FDG focal uptake in the myocardium as well as its correlation with coronary vessel calcifications.</p></div><div><h3>Material and methods</h3><p>A total of 130 patients who underwent an oncological PET/CT study were reviewed retrospectively. Sixty-five had undergone a myocardial perfusion study because of clinical suspicion of coronary artery disease (group 1). There were no significant differences in age and gender regarding another group of the same series (n = 65; group 2). Focal myocardial <sup>18</sup>F-FDG uptake and the presence of coronary vessel calcifications were identified by 2 independent observers.</p></div><div><h3>Results</h3><p>Group 1: in 18 out of 65 patients (28%) focal myocardial <sup>18</sup>F-FDG uptake was identified (5 had 2 foci; total: 23 foci). In 43 out of 65 studies (66%), calcification was identified in the coronary vessels. Group 2: in 6 out of 65 patients (9%) focal myocardial <sup>18</sup>F-FDG uptake was identified (1 had 2 foci; total: 7 foci). In 17 out of 65 studies (26%), calcification was identified in the coronary vessels.</p><p>Comparative analysis: focal myocardial <sup>18</sup>F-FDG uptake and coronary vessel calcifications were more frequent in the group 1 patients (p < 0.01).</p><p>There was no correlation between the presence of coronary vessel calcifications and focal myocardial <sup>18</sup> F-FDG uptake in individual patients in both groups (group 1: p = 0.7; group 2: p = 0.163).</p></div><div><h3>Conclusions</h3><p>PET/CT allows simultaneous assessment of focal myocardial <sup>18</sup>F-FDG uptake and myocardial vessel calcifications. Patients with clinical suspicion of coronary artery disease have a higher incidence of focal myocardial <sup>18</sup>F-FDG uptake and coronary calcifications. However, <sup>18</sup>F-FDG focal uptake is often observed in sites remote from those with calcification.</p></div>","PeriodicalId":101111,"journal":{"name":"Revista Espa?ola de Medicina Nuclear (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70002-X","citationCount":"1","resultStr":"{\"title\":\"Incidence of focal myocardial 18F-FDG uptake and correlation with coronary calcifications by PET/CT\",\"authors\":\"J.R. García, M. Soler, S. Fuertes, E. Riera, A. Moreno, F. Lomeña, I. Carrio\",\"doi\":\"10.1016/S1578-200X(11)70002-X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>To evaluate the incidence of <sup>18</sup>F-FDG focal uptake in the myocardium as well as its correlation with coronary vessel calcifications.</p></div><div><h3>Material and methods</h3><p>A total of 130 patients who underwent an oncological PET/CT study were reviewed retrospectively. Sixty-five had undergone a myocardial perfusion study because of clinical suspicion of coronary artery disease (group 1). There were no significant differences in age and gender regarding another group of the same series (n = 65; group 2). Focal myocardial <sup>18</sup>F-FDG uptake and the presence of coronary vessel calcifications were identified by 2 independent observers.</p></div><div><h3>Results</h3><p>Group 1: in 18 out of 65 patients (28%) focal myocardial <sup>18</sup>F-FDG uptake was identified (5 had 2 foci; total: 23 foci). In 43 out of 65 studies (66%), calcification was identified in the coronary vessels. Group 2: in 6 out of 65 patients (9%) focal myocardial <sup>18</sup>F-FDG uptake was identified (1 had 2 foci; total: 7 foci). In 17 out of 65 studies (26%), calcification was identified in the coronary vessels.</p><p>Comparative analysis: focal myocardial <sup>18</sup>F-FDG uptake and coronary vessel calcifications were more frequent in the group 1 patients (p < 0.01).</p><p>There was no correlation between the presence of coronary vessel calcifications and focal myocardial <sup>18</sup> F-FDG uptake in individual patients in both groups (group 1: p = 0.7; group 2: p = 0.163).</p></div><div><h3>Conclusions</h3><p>PET/CT allows simultaneous assessment of focal myocardial <sup>18</sup>F-FDG uptake and myocardial vessel calcifications. Patients with clinical suspicion of coronary artery disease have a higher incidence of focal myocardial <sup>18</sup>F-FDG uptake and coronary calcifications. However, <sup>18</sup>F-FDG focal uptake is often observed in sites remote from those with calcification.</p></div>\",\"PeriodicalId\":101111,\"journal\":{\"name\":\"Revista Espa?ola de Medicina Nuclear (English Edition)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S1578-200X(11)70002-X\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Espa?ola de Medicina Nuclear (English Edition)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1578200X1170002X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espa?ola de Medicina Nuclear (English Edition)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1578200X1170002X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Incidence of focal myocardial 18F-FDG uptake and correlation with coronary calcifications by PET/CT
Objective
To evaluate the incidence of 18F-FDG focal uptake in the myocardium as well as its correlation with coronary vessel calcifications.
Material and methods
A total of 130 patients who underwent an oncological PET/CT study were reviewed retrospectively. Sixty-five had undergone a myocardial perfusion study because of clinical suspicion of coronary artery disease (group 1). There were no significant differences in age and gender regarding another group of the same series (n = 65; group 2). Focal myocardial 18F-FDG uptake and the presence of coronary vessel calcifications were identified by 2 independent observers.
Results
Group 1: in 18 out of 65 patients (28%) focal myocardial 18F-FDG uptake was identified (5 had 2 foci; total: 23 foci). In 43 out of 65 studies (66%), calcification was identified in the coronary vessels. Group 2: in 6 out of 65 patients (9%) focal myocardial 18F-FDG uptake was identified (1 had 2 foci; total: 7 foci). In 17 out of 65 studies (26%), calcification was identified in the coronary vessels.
Comparative analysis: focal myocardial 18F-FDG uptake and coronary vessel calcifications were more frequent in the group 1 patients (p < 0.01).
There was no correlation between the presence of coronary vessel calcifications and focal myocardial 18 F-FDG uptake in individual patients in both groups (group 1: p = 0.7; group 2: p = 0.163).
Conclusions
PET/CT allows simultaneous assessment of focal myocardial 18F-FDG uptake and myocardial vessel calcifications. Patients with clinical suspicion of coronary artery disease have a higher incidence of focal myocardial 18F-FDG uptake and coronary calcifications. However, 18F-FDG focal uptake is often observed in sites remote from those with calcification.