Fabiana Lucena Rocha, Tarciana Nobre de Menezes, Rômulo Lustosa Pimenteira de Melo, Dixis Figueroa Pedraza
{"title":"Correlation between indicators of abdominal obesity and serum lipids in the elderly","authors":"Fabiana Lucena Rocha, Tarciana Nobre de Menezes, Rômulo Lustosa Pimenteira de Melo, Dixis Figueroa Pedraza","doi":"10.1016/S2255-4823(13)70429-6","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70429-6","url":null,"abstract":"<div><h3>Objective</h3><p>To verify the correlation between anthropometric indicators of abdominal obesity and serum lipids in the elderly.</p></div><div><h3>Methods</h3><p>Cross-sectional, descriptive, and analytical study conducted with elderly individuals of both genders enrolled in the Family Health Strategy Program of Campina Grande/PB. Abdominal obesity was assessed by waist circumference (WC), abdominal circumference (AC), and waist/hip ratio (WHR). Lipid profile was verified by levels of triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and non-high density lipoprotein (non-HDL).</p></div><div><h3>Results</h3><p>A total of 321 elderly patients were evaluated (67.6% women). There were significant correlations between abdominal obesity indicators and lipid levels only in the group of women. WC, AC, and WHR correlated with TG and HDL. Only WHR showed correlation with non-HDL. The highest correlations were observed between WHR and TG (r<!--> <!-->=<!--> <!-->0.292, p<!--> <!--><<!--> <!-->0.01) and between WC and HDL (r<!--> <!-->=<!--> <!-->-0.281, p<!--> <!--><<!--> <!-->0.01). WC was a predictor of 9.2% of the variation in HDL, and WHR was a predictor of 7.3% of the variation in TG.</p></div><div><h3>Conclusion</h3><p>The indicators of abdominal obesity that best correlated with serum lipids in elderly women were WC and WHR. They were predictors of alterations in HDL and TG levels in women, respectively</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 1","pages":"Pages 48-55"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70429-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91637544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Alternative for pre-anesthetic sedation and for surgical procedures in children: use of intranasal midazolam","authors":"Eduardo Mekitarian Filho","doi":"10.1016/S2255-4823(13)70420-X","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70420-X","url":null,"abstract":"","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 1","pages":"Pages 3-4"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70420-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91689670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Isabel do Nascimento , Alfredo de Almeida Cunha , Sandra Regina dos Santos Muri Oliveira , Glaucimara Gonzaga Nunes , Felipe Silva Alvarez , Eduardo Loyola Villas Bôas
{"title":"Misoprostol use under routine conditions for termination of pregnancies with intrauterine fetal death","authors":"Maria Isabel do Nascimento , Alfredo de Almeida Cunha , Sandra Regina dos Santos Muri Oliveira , Glaucimara Gonzaga Nunes , Felipe Silva Alvarez , Eduardo Loyola Villas Bôas","doi":"10.1016/S2255-4823(13)70487-9","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70487-9","url":null,"abstract":"<div><h3>Objective</h3><p>To analyze the misoprostol use in pregnancies with intrauterine fetal death (IUFD), considering mode of delivery and induction-delivery interval.</p></div><div><h3>Methods</h3><p>Descriptive study including 171 pregnant women with IUFD, in the second or third trimester, submitted to labor induction with vaginal misoprostol and/or induc-tion/augmentation with intravenous oxytocin, from 2005 to 2008, at a teaching-hospital of the Brazilian Unified Health System (Sistema Único de Saúde - SUS).</p></div><div><h3>Results</h3><p>Misoprostol alone (treatment A), misoprostol plus oxytocin (treatment B), and oxytocin alone (treatment C) were administered in 9.3%, 19.9%, and 70.8% of the cases, respectively. One-third of pregnancies were less than 28 weeks, and 2.9% required a cae-sarean section. The percentage of vaginal delivery in treatments A and B combined (98.0%) was similar to treatment C (96.7%). The mean induction-delivery interval was 15.4hours. Comparing multiple groups, the mean induction-delivery interval was significantly shorter in treatment A (20.1hours) than in treatment B (33.3hours), and was longer than in treatment C (9.7hours). The majority (71%) of cases required a single administration of misoprostol, and the total dosage was lower in treatment A (mean: 98.4<!--> <!-->μg) compared with treatment B (mean: 157.0<!--> <!-->μg).</p></div><div><h3>Conclusion</h3><p>Misoprostol effectively contributed to delivery of IUFD by vaginal route assisted under routine conditions of a public health service in Brazil, demonstrating its importance in cases resistant to usual induction methods, and its availability in Brazilian public health services is recommended.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 4","pages":"Pages 354-359"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70487-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137438541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian Association of Physical Medicine and Rehabilitation (Associação Brasileira de Medicina Física e Reabilitação)
{"title":"Chronic nonspecific low back pain: Rehabilitation","authors":"Brazilian Association of Physical Medicine and Rehabilitation (Associação Brasileira de Medicina Física e Reabilitação)","doi":"10.1016/S2255-4823(13)70516-2","DOIUrl":"10.1016/S2255-4823(13)70516-2","url":null,"abstract":"","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 6","pages":"Pages 536-553"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70516-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132501118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanessa Prado dos Santos , Carlos Alberto Silveira Alves , Cícero Fidelis , José Siqueira de Araújo Filho
{"title":"Arteriographic findings in diabetic and nondiabetic patients with critical limb ischemia","authors":"Vanessa Prado dos Santos , Carlos Alberto Silveira Alves , Cícero Fidelis , José Siqueira de Araújo Filho","doi":"10.1016/S2255-4823(13)70519-8","DOIUrl":"10.1016/S2255-4823(13)70519-8","url":null,"abstract":"<div><h3>Objective</h3><p>To compare angiographic findings of diabetic and nondiabetic patients with critical limb ischemia.</p></div><div><h3>Methods</h3><p>We included 161 patients with infrainguinal critical limb ischemia (CLI). We evaluated the clinical and arteriographic (number and presence of opacification of leg arteries) of the two groups of patients. Statistical analysis was performed using EPI-INFO.</p></div><div><h3>Results</h3><p>Most patients were category 5 of Rutherford's Classification and had femoropopliteal disease. Seventy-two percent of nondiabetic and 67% of diabetic patients had opacification of the fibular artery (<em>p</em> <!-->=<!--> <!-->0.25), which is the most present artery in both groups. Diabetic patients had less opacification of the posterior tibial artery in the univariate analysis (29% vs. 47%, <em>p</em> <!-->=<!--> <!-->0.008). But only female sex showed a significant risk for the absence of the posterior tibial artery in logistic regression (OR<!--> <!-->=<!--> <!-->2.6; <em>p</em> <!-->=<!--> <!-->0.01).</p></div><div><h3>Conclusion</h3><p>The peroneal artery was the most frequently found artery in angiograms of diabetic and nondiabetic patients with CLI. Diabetic and nondiabetic patients did not differ in angiographic findings of the leg.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 6","pages":"Pages 557-562"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70519-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75885932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nelson Wolosker , Mariana Krutman , Paulo Kauffman , Rafael Pessanha de Paula , Jose Ribas M. de Campos , Pedro Puech-Leão
{"title":"Effectiveness of oxybutynin for treatment of hyperhidrosis in overweight and obese patients","authors":"Nelson Wolosker , Mariana Krutman , Paulo Kauffman , Rafael Pessanha de Paula , Jose Ribas M. de Campos , Pedro Puech-Leão","doi":"10.1016/S2255-4823(13)70447-8","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70447-8","url":null,"abstract":"<div><h3>Objective</h3><p>Until the present moment, the lack of efficient therapeutic options available for hyperhidrosis treatment in obese patients has left this population without prospect of clinical or quality of life (QOL) improvements. Outcomes of oxybutynin treatment for overweight and obese patients with hyperhidrosis are unknown. This study aims to investigate the results related to clinical and QOL improvements in this specific population, submitted to a 12-week protocol treatment with oxybutynin.</p></div><div><h3>Methods</h3><p>559 patients with palmar and axillary hyperhidrosis, routinely followed in this service, were divided into the groups, according to their body mass index (BMI) (< 25<!--> <!-->kg/m<sup>2</sup>; 25 < BMI < 30<!--> <!-->kg/m<sup>2</sup>, > 30<!--> <!-->kg/m<sup>2</sup>). Improvements in QOL and in the level of hyperhidrosis were analyzed after 12 weeks of protocol treatment with oxybutynin. These parameters were investigated using a scoring system based on a scientifically validated clinical questionnaire, applied before and after treatment.</p></div><div><h3>Results</h3><p>67.8% of the overweight sample group and 63% of the obese patients presented “partial” or “great” improvement in the level of hyperhidrosis. Over 65% of patients demonstrated improvement in QOL (“much better” or “slightly better”) for all three groups, with no statistical difference between them. The only adverse event associated with oxybutynin was dry mouth, observed in 63.0% of the patients.</p></div><div><h3>Conclusion</h3><p>Overweight and obese patients with palmar or axillary hyperhidrosis present significant improvement in QOL after treatment with oxybutynin, and the results are comparable to those of normal weight individuals.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 2","pages":"Pages 143-147"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70447-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136551302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Cristina Ritter Mazzini , Milena Grossi Blumer , Eduardo Luiz Hoehne , Kátia Regina Leoni Silva Lima de Queiroz Guimarães , Bruno Caramelli , Luciana Fornari , Sônia Valéria Pinheiro Malheiros
{"title":"Diabetes mellitus risk screening of parents of private school students in the city of Jundiaí, São Paulo, Brazil","authors":"Maria Cristina Ritter Mazzini , Milena Grossi Blumer , Eduardo Luiz Hoehne , Kátia Regina Leoni Silva Lima de Queiroz Guimarães , Bruno Caramelli , Luciana Fornari , Sônia Valéria Pinheiro Malheiros","doi":"10.1016/S2255-4823(13)70446-6","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70446-6","url":null,"abstract":"<div><h3>Objective</h3><p>To screen the risk of developing diabetes mellitus type 2 (DM2) in adult individuals.</p></div><div><h3>Methods</h3><p>Several risk factors for DM2 (sedentary lifestyle, previous coronary artery disease, hyperglycemia-inducing medications, body mass index [BMI], blood pressure, serum triglyceride, and HDL-cholesterol levels) were assessed in 314 adults as a function of gender and age group.</p></div><div><h3>Results</h3><p>73.2% of the population had two or more concurrent risk factors and 26.8% had less than two factors. The occurrence of risk factors for DM2 development was observed even in young adults, and the risk factors are likely associated with aging. Differences in risk factors and incidence were observed between men and women in the same age group.</p></div><div><h3>Conclusion</h3><p>Regardless the age studied, the most prevalent risk factors associated with DM2 were: BMI, sedentary lifestyle, and reduced serum HDL-cholesterol, which are modifiable, thus increasing the importance of preventive measures. Discrepancies found in prevalent risk factors in men and women also suggest that sociocultural differences influence the risk of developing DM.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 2","pages":"Pages 136-142"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70446-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136551579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lipid profile of HIV-infected patients in relation to antiretroviral therapy: a review","authors":"Suelen Jorge Souza , Liania Alves Luzia , Sigrid Sousa Santos , Patrícia Helen Carvalho Rondó","doi":"10.1016/S2255-4823(13)70454-5","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70454-5","url":null,"abstract":"<div><p>This study reviewed the lipid profile of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients in relation to use of antiretroviral therapy (ART), and its different classes of drugs. A total of 190 articles published in peer-reviewed journals were retrieved from PubMed and LILACS databases; 88 of them met the selection criteria and were included in the review. Patients with HIV/AIDS without ART presented an increase of triglycerides and decreases of total cholesterol, low density lipoprotein (LDL-c), and high density lipoprotein (HDL-c) levels. Distinct ART regimens appear to promote different alterations in lipid metabolism. Protease inhibitors, particularly indinavir and lopinavir, were commonly associated with hypercholesterolemia, high LDL-c, low HDL-c, and hypertriglyceridemia. The protease inhibitor atazanavir is apparently associated with a more advantageous lipid profile. Some nucleoside reverse-transcriptase inhibitors (didanosine, stavudine, and zidovudine) induced lipoatrophy and hypertriglyceridemia, whereas abacavir increased the risk of cardiovascular diseases even in the absence of apparent lipid disorders, and tenofovir resulted in lower levels of cholesterol and triglycerides. Although non-nucleoside reverse-transcriptase inhibitors predisposed to hypertriglyceridemia and hypercholesterolemia, nevirapine was particularly associated with high HDL-c levels, a protective factor against cardiovascular diseases. Therefore, the infection itself, different classes of drugs, and some drugs from the same class of ART appear to exert distinct alterations in lipid metabolism.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 2","pages":"Pages 186-198"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70454-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136551347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}