Revista da Associa??o Médica Brasileira (English Edition)最新文献

{"title":"Reply to “Muscular static strength test performance and health: absolute or relative values?”","authors":"Timothy Gustavo Cavazzotto , Luriam Tratis , Sandra Aires Ferreira , Rômulo Araújo Fernandes , Marcos Roberto Queiroga","doi":"10.1016/S2255-4823(13)70477-6","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70477-6","url":null,"abstract":"","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 4","pages":"Pages 310-311"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70477-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137439382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic surgery and cancer","authors":"Elias Jirjoss Ilias","doi":"10.1016/S2255-4823(13)70518-6","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70518-6","url":null,"abstract":"","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 6","pages":"Pages 555-556"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70518-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137408203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doppler velocimetry of the fetal middle cerebral artery and other parameters of fetal well-being in neonatal survival during pregnancies with placental insufficiency","authors":"Roseli Mieko Yamamoto Nomura,&nbsp;Juliana Ikeda Niigaki,&nbsp;Flávia Thiemi Horigome,&nbsp;Rossana Pulcineli Vieira Francisco,&nbsp;Marcelo Zugaib","doi":"10.1016/S2255-4823(13)70493-4","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70493-4","url":null,"abstract":"<div><h3>Objective</h3><p>To study the Doppler velocimetry of the fetal middle cerebral artery in pregnancies complicated by placental insufficiency, and to verify its role in the prognosis of neonatal survival.</p></div><div><h3>Methods</h3><p>This was a prospective study of 93 pregnant women with diagnosis of placental insufficiency detected before the 34^th week of pregnancy. Placental insufficiency was characterized by abnormal umbilical artery (UA) Doppler (&gt; 95^th percentile). The following parameters were analyzed: umbilical artery (UA) pulsatility index (PI); middle cerebral artery (MCA) PI; brain-placenta ratio – BPR (MCA-PI/UA-PI); MCA peak systolic velocity (MCA-PSV); and PI for veins (PIV) of ductus venosus (DV). The parameters were analyzed in terms of absolute values, z-scores (standard deviations from the mean), or multiples of the median (MoM). The outcome investigated was neonatal death during the hospitalization period after birth.</p></div><div><h3>Results</h3><p>Of the 93 pregnancies analyzed, there were 25 (26.9%) neonatal deaths. The group that died, when compared to the survival group, presented a significant association with the diagnosis of absent or reversed end-diastolic flow (88% vs. 23.6%, p<!--> <!-->&lt;<!--> <!-->0.001), with a higher median of UA PI (2.9 vs. 1.7, p<!--> <!-->&lt;<!--> <!-->0.001) and UA PI z-score (10.4 vs. 4.9, p<!--> <!-->&lt;<!--> <!-->0.001); higher MCA-PSV MoM (1.4 vs. 1.1, p<!--> <!-->=<!--> <!-->0.012); lower BPR (0.4 vs. 0.7, p<!--> <!-->&lt;<!--> <!-->0.001); higher PIV-DV (1.2 vs. 0.8, p<!--> <!-->&lt;<!--> <!-->0.001) and DV z-score (3.6 vs. 0.6, p<!--> <!-->&lt;<!--> <!-->0.001). In the logistic regression, the independent variables predictive of neonatal death were: gestational age at birth (OR<!--> <!-->=<!--> <!-->0.45; 95% CI: 0.3 to 0.7; p<!--> <!-->&lt;<!--> <!-->0.001) and UA PI z-score (OR<!--> <!-->=<!--> <!-->1.14, 95% CI: 1.0 to 1.3, p<!--> <!-->=<!--> <!-->0.046).</p></div><div><h3>Conclusion</h3><p>Despite the association verified by the univariate analysis between neonatal death and the parameters of fetal cerebral Doppler velocimetry, the multivariate analysis identified prematurity and degree of insufficiency of placental circulation as independent factors related to neonatal death in pregnancies complicated by placental insufficiency.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 4","pages":"Pages 392-399"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70493-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72279336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic syndrome in obese adolescents: what is enough?","authors":"Leticia Esposito Sewaybricker ,&nbsp;Maria Ângela R.G.M. Antonio ,&nbsp;Roberto Teixeira Mendes ,&nbsp;Antonio de Azevedo Barros Filho ,&nbsp;Mariana Porto Zambon","doi":"10.1016/S2255-4823(13)70431-4","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70431-4","url":null,"abstract":"<div><h3>Objective</h3><p>To study the agreement among three distinct criteria for metabolic syndrome (MS) adapted to adolescents, and to identify associated factors for MS.</p></div><div><h3>Methods</h3><p>Cross-sectional study with 65 obese subjects aged 10 to 18 years, attended to at the Outpatient Clinic for Obese Children and Adolescents at the Clinical Hospital of the Universidade Estadual de Campinas (Unicamp). MS was defined using the criteria of the World Health Organization (WHO), the International Diabetes Federation (IDF), and the Adult Treatment Panel III (ATP III). Clinical, anthropometrical, and laboratorial data were associated to MS.</p></div><div><h3>Results</h3><p>From the 65 subjects, none had MS according to the WHO criteria, while 18 were diagnosed with MS (27.6%) according to the IDF, and 19 (29.2%) according to the ATP III. Agreement between IDF and ATP III was excellent (kappa 81%). In this study, puberty and triglycerides levels showed significant statistical difference when comparing subjects with and without MS, the first for ATP III (p<!--> <!-->=<!--> <!-->0.03), and the second for IDF (p<!--> <!-->=<!--> <!-->0.005) and ATP III (p<!--> <!-->=<!--> <!-->0.001) criteria.</p></div><div><h3>Conclusion</h3><p>The WHO criteria does not seem to be adequate for adolescents. IDF and ATP III criteria had an excellent agreement. Puberty and triglycerides were associated with MS</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 1","pages":"Pages 64-71"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70431-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90018574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonalcoholic fatty liver disease and its association with metabolic syndrome in the preoperative period in patients undergoing bariatric surgery","authors":"Bruna Z. Schild,&nbsp;Luciano Neto Santos,&nbsp;Márcia Keller Alves","doi":"10.1016/S2255-4823(13)70449-1","DOIUrl":"10.1016/S2255-4823(13)70449-1","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the association between nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) in the preoperative period in patients undergoing bariatric surgery.</p></div><div><h3>Methods</h3><p>A total of 68 medical records of patients from a center for advanced treatment of obesity in the city of Caxias do Sul, state of Rio Grande do Sul, Brazil, were reviewed. The variables analyzed were gender, age, biochemical parameters (fasting glucose, HDL-cholesterol and triglycerides), abdominal ultrasound, blood pressure, and anthropometric data (weight, height, waist circumference, and body mass index [BMI]). The diagnosis of NAFLD was obtained by abdominal ultrasonography; the diagnosis of of MS was obtained according to the protocol described by the National Cholesterol Education Program's Adult Treatment Panel III, updated by the American Heart Association; and the National Heart, Lung, and Blood Institute.</p></div><div><h3>Results</h3><p>72.1% (n<!--> <!-->=<!--> <!-->49) of the sample consisted of females, and the mean age for the sample was 37.57<!--> <!-->±<!--> <!-->10.29 years. The mean weight was 123.14<!--> <!-->±<!--> <!-->25.40<!--> <!-->kg, mean height was 1.67<!--> <!-->±<!--> <!-->0.09 m, and mean BMI was 56.24<!--> <!-->±<!--> <!-->9.30<!--> <!-->kg/m². A total of 60% (n<!--> <!-->=<!--> <!-->27) of patients with MS (p<!--> <!-->=<!--> <!-->0.008), 63.4% (n<!--> <!-->=<!--> <!-->26) of patients with hypertension (p<!--> <!-->=<!--> <!-->0.013), and 66.7% (n<!--> <!-->=<!--> <!-->18) of patients with altered glucose levels (p<!--> <!-->=<!--> <!-->0.028) were diagnosed with NAFLD.</p></div><div><h3>Conclusion</h3><p>The results of this study showed that the diagnosis of MS, as well as the presence of disorders associated with this syndrome (obesity, hypertension, and high blood glucose levels) are strongly associated with the presence of NAFLD.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 2","pages":"Pages 155-160"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70449-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74837365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of food preparation methods on atherosclerosis prevention","authors":"Carlos Scherr ,&nbsp;Jorge Pinto Ribeiro","doi":"10.1016/S2255-4823(13)70448-X","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70448-X","url":null,"abstract":"<div><h3>Objective</h3><p>To analyze the influence of food preparation methods on the composition of fatty acids and cholesterol in foods.</p></div><div><h3>Methods</h3><p>The chemical composition of cholesterol and fatty acids was analyzed in eight different types of meat and feijoada¹ in relation to different methods of preparation.</p></div><div><h3>Results</h3><p>Feijoada, when prepared with the beans and meats in separate pots, has less cholesterol (12.1 <em>vs.</em> 16.1<!--> <!-->mg, respectively, p<!--> <!-->=<!--> <!-->0.005) and saturated fat (1.4 <em>vs.</em> 1.9<!--> <!-->mg, p<!--> <!-->=<!--> <!-->0.046) than when it is prepared in a single pot. Broiled chicken without the skin has less saturated fat when compared with skinless fried chicken (1,505 <em>vs.</em> 7,645<!--> <!-->mg, p<!--> <!-->=<!--> <!-->0.049). Broiled shrimp also has a lower saturated fat content than fried shrimp (532 <em>vs.</em> 1,262<!--> <!-->mg, p<!--> <!-->=<!--> <!-->0.049). Broiled ribeye steak without fat has a lower cholesterol content when compared with the fried steak (102 <em>vs.</em> 114<!--> <!-->mg, p<!--> <!-->=<!--> <!-->0.049).</p></div><div><h3>Conclusion</h3><p>The analysis indicates that the method of food preparation influences the fat content of foods, with potential impact on the prescription of low-fat and low-cholesterol diets.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 2","pages":"Pages 148-154"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70448-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136551578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of physical exercises and nutritional guidance on the cardiovascular risk profile of obese children","authors":"Lisiane Schilling Poeta ,&nbsp;Maria de Fátima da Silva Duarte ,&nbsp;Bruno Caramelli ,&nbsp;Jorge Mota ,&nbsp;Isabela de Carlos Back Giuliano","doi":"10.1016/S2255-4823(13)70430-2","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70430-2","url":null,"abstract":"<div><h3>Objective</h3><p>To analyze the effects of a supervised physical exercise and nutritional guidance program, conducted with a playful basis, on the cardiovascular risk profile of obese children.</p></div><div><h3>Methods</h3><p>Forty-four children aged between 8 and 11 years, divided into two groups, were paired by gender and age: intervention group (n<!--> <!-->=<!--> <!-->22) and control group (n<!--> <!-->=<!--> <!-->22). The following parameters were measured before and after the intervention: body mass, height, waist circumference, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, fasting glucose, high-sensitive C-reactive protein, blood pressure, and carotid intima-media thickness. Both groups continued their traditional medical treatment. The case group exercised with recreational activities three times a week during 12 weeks, and participated in a weekly nutritional guidance session. The control group did not participate in the intervention described. Descriptive statistics, paired and unpaired Student's t-test, Mann-Whitney's U test, and the Wilcoxon test were used, with a significance level of p &lt; 0.05.</p></div><div><h3>Results</h3><p>32 children concluded the study (16 in each group). At the end of the study, the case group showed a significant reduction in the body mass index (BMI) (p<!--> <!-->=<!--> <!-->0.001), total cholesterol (p<!--> <!-->=<!--> <!-->0.001), LDL cholesterol (p<!--> <!-->=<!--> <!-->0.001), diastolic blood pressure (p<!--> <!-->=<!--> <!-->0.010), and average (p<!--> <!-->=<!--> <!-->0.003) and maximum (p<!--> <!-->=<!--> <!-->0.002) carotid intima-media thickness. The control group showed a significant increase in waist circumference (p<!--> <!-->=<!--> <!-->0.001), blood glucose (p<!--> <!-->=<!--> <!-->0.025), C-reactive protein (p<!--> <!-->=<!--> <!-->0.016), a reduction of HDL cholesterol (p<!--> <!-->=<!--> <!-->0.012) and total cholesterol (p<!--> <!-->=<!--> <!-->0.042), and an increase in the average (p<!--> <!-->=<!--> <!-->0.012) and maximum (p<!--> <!-->=<!--> <!-->0.024) carotid intima-media thickness.</p></div><div><h3>Conclusion</h3><p>The program proved effective in the reduction of obesity indicators and of the intima-media thickness, a direct and early signal of atherosclerosis.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 1","pages":"Pages 56-63"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70430-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91682840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma concentration of IL-6 and TNF-α and its relationship with zincemia in obese women","authors":"Maura Cristina Porto Feitosa ,&nbsp;Vanessa Batista de Sousa Lima ,&nbsp;José Machado Moita Neto ,&nbsp;Dilina do Nascimento Marreiro","doi":"10.1016/S2255-4823(13)70501-0","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70501-0","url":null,"abstract":"<div><h3>Objective</h3><p>In obesity, the excessive adipose tissue increases the synthesis of inflammatory cytokines, which appear to alter the metabolism of minerals, such as zinc. However, the mechanisms involved remain unclear. This study investigated whether the concentrations of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in plasma can to influence biochemical parameters of zinc in obese women.</p></div><div><h3>Methods</h3><p>Seventy-six pre-menopausal women, aged between 20 and 50 years, were divided into two groups: the case group, composed of obese women (n<!--> <!-->=<!--> <!-->37) and the control group, composed of non-obese women (n<!--> <!-->=<!--> <!-->39). Analysis of the plasmatic and erythrocytary zinc, and plasmatic cytokines were conducted by flame atomic absorption spectrophotometry and by ELISA, respectively.</p></div><div><h3>Results</h3><p>The plasmatic zinc and concentrations of IL-6 in plasma did not show significant differences between obese women and controls (p<!--> <!-->&gt;<!--> <!-->0.05). The erythrocytary zinc was 36.4<!--> <!-->±<!--> <!-->15.0<!--> <!-->μg/gHb in the case group, and 45.4<!--> <!-->±<!--> <!-->14.3<!--> <!-->μg/gHb (p<!--> <!-->=<!--> <!-->0.025) in the control group. The concentrations of TNF-α in plasma were 42.0<!--> <!-->±<!--> <!-->11.9<!--> <!-->pg/mL and 19.0<!--> <!-->±<!--> <!-->1.0<!--> <!-->pg/mL in obese women and in controls, respectively (p<!--> <!-->&lt;<!--> <!-->0.001). The plasmatic zinc had a significant negative correlation with the values of TNF α (r<!--> <!-->=<!--> <!-->−0.44, p<!--> <!-->=<!--> <!-->0.015).</p></div><div><h3>Conclusion</h3><p>Obese women presented lower concentrations of erythrocytary zinc than the control group. The study demonstrated a probable influence of the inflammatory process on metabolism of zinc in obese patients.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 5","pages":"Pages 429-434"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70501-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72283496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venous thromboprophylaxis in medical patients: an application review","authors":"Mariana Nassif Kerbauy ,&nbsp;Fabio Ynoe de Moraes ,&nbsp;Lucila Nassif Kerbauy ,&nbsp;Lucieni de Oliveira Conterno ,&nbsp;Silene El-Fakhouri","doi":"10.1016/S2255-4823(13)70466-1","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70466-1","url":null,"abstract":"<div><h3>Objective</h3><p>Routine thromboprophylaxis, despite its well-known effectiveness and the fact that venous thromboembolism is a potentially avoidable condition, is not fully established in clinical practice. The objectives of the present study were to determine how often thromboprophylaxis is used and the presence of thromboembolism risk factors, and to verify the appropriateness of its use in medical inpatients, assuming a long-standing national guideline as a parameter.</p></div><div><h3>Methods</h3><p>This was a retrospective cross-sectional study, involving inpatients with medical conditions in the adult general ward of a faculty hospital. The review was based on a defined guideline.</p></div><div><h3>Results</h3><p>146 patients were included in the review. At least one risk factor for venous thrombo embolism was found in 94.5%. In 130 (89%) patients, prophylactic heparin was indicated, and some kind of heparin was prescribed in 73.3%. Regarding the adequacy of prophylaxis, 53.4% of prescriptions were correct regarding prophylaxis indication and dose; 24% had incorrect dose or frequency of use; 19.2% had no prophylaxis prescription, although it was indicated; and in five cases (3.4%), the drug was prescribed, even though it was not indicated.</p></div><div><h3>Conclusion</h3><p>Thromboprophylaxis is underused in this population, and an inappropriate dose was prescribed in 50% of cases. Therefore, future studies and interventions should include an educational program started from the emergency department care, an essential step to bring evidence closer to clinical practice.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 3","pages":"Pages 258-264"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70466-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137161957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of dexamethasone in the prophylaxis of nausea and vomiting during the postoperative period of laparoscopic cholecystectomy","authors":"Wanderley Marques Bernardo ,&nbsp;Felipe Toyama Aires","doi":"10.1016/S2255-4823(13)70492-2","DOIUrl":"https://doi.org/10.1016/S2255-4823(13)70492-2","url":null,"abstract":"<div><h3>Objective</h3><p>To verify the efficacy of dexamethasone in the prophylaxis of nausea and vomiting in patients submitted to laparoscopic cholecystectomy.</p></div><div><h3>Methods</h3><p>This was a systematic review of the literature through the MEDLINE, Embase, and LILACS databases. Only controlled and randomized clinical trials comparing dexamethasone to placebo in the prophylaxis of nausea and vomiting in patients submitted to laparoscopic cholecystectomy were included.</p></div><div><h3>Results</h3><p>The results of this review were based on data from 12 controlled and randomized clinical trials, totaling 947 patients. The group of patients who received preoperative dexamethasone showed lower incidence of nausea (number needed to treat [NNT] = 7), vomiting (NNT = 7), and need for smaller doses of rescue antiemetics (NNT = 6).</p></div><div><h3>Conclusion</h3><p>The preoperative infusion of 8<!--> <!-->mg of dexamethasone decreases the risk of complications in the postoperative period for patients submitted to laparoscopic cholecystectomy.</p></div>","PeriodicalId":101100,"journal":{"name":"Revista da Associa??o Médica Brasileira (English Edition)","volume":"59 4","pages":"Pages 387-391"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2255-4823(13)70492-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137439361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}