Effects of physical exercises and nutritional guidance on the cardiovascular risk profile of obese children

Lisiane Schilling Poeta , Maria de Fátima da Silva Duarte , Bruno Caramelli , Jorge Mota , Isabela de Carlos Back Giuliano
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引用次数: 12

Abstract

Objective

To analyze the effects of a supervised physical exercise and nutritional guidance program, conducted with a playful basis, on the cardiovascular risk profile of obese children.

Methods

Forty-four children aged between 8 and 11 years, divided into two groups, were paired by gender and age: intervention group (n = 22) and control group (n = 22). The following parameters were measured before and after the intervention: body mass, height, waist circumference, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, fasting glucose, high-sensitive C-reactive protein, blood pressure, and carotid intima-media thickness. Both groups continued their traditional medical treatment. The case group exercised with recreational activities three times a week during 12 weeks, and participated in a weekly nutritional guidance session. The control group did not participate in the intervention described. Descriptive statistics, paired and unpaired Student's t-test, Mann-Whitney's U test, and the Wilcoxon test were used, with a significance level of p < 0.05.

Results

32 children concluded the study (16 in each group). At the end of the study, the case group showed a significant reduction in the body mass index (BMI) (p = 0.001), total cholesterol (p = 0.001), LDL cholesterol (p = 0.001), diastolic blood pressure (p = 0.010), and average (p = 0.003) and maximum (p = 0.002) carotid intima-media thickness. The control group showed a significant increase in waist circumference (p = 0.001), blood glucose (p = 0.025), C-reactive protein (p = 0.016), a reduction of HDL cholesterol (p = 0.012) and total cholesterol (p = 0.042), and an increase in the average (p = 0.012) and maximum (p = 0.024) carotid intima-media thickness.

Conclusion

The program proved effective in the reduction of obesity indicators and of the intima-media thickness, a direct and early signal of atherosclerosis.

体育锻炼和营养指导对肥胖儿童心血管风险的影响
目的分析寓教于乐的有监督的体育锻炼和营养指导方案对肥胖儿童心血管风险的影响。方法44例8 ~ 11岁儿童按性别、年龄分组分为干预组(n = 22)和对照组(n = 22)。在干预前后测量以下参数:体重、身高、腰围、总胆固醇、HDL胆固醇、LDL胆固醇、甘油三酯、空腹血糖、高敏c反应蛋白、血压、颈动脉内膜-中膜厚度。两组人都继续接受传统的治疗。病例组在12周内每周进行3次休闲运动,并参加每周一次的营养指导。对照组不参与上述干预。采用描述性统计、配对和非配对学生t检验、Mann-Whitney U检验和Wilcoxon检验,显著性水平为p <0.05.结果32例患儿完成研究,每组16例。在研究结束时,病例组的身体质量指数(BMI) (p = 0.001)、总胆固醇(p = 0.001)、低密度脂蛋白胆固醇(p = 0.001)、舒张压(p = 0.010)、颈动脉内膜-中膜平均厚度(p = 0.003)和最大厚度(p = 0.002)显著降低。对照组患者腰围(p = 0.001)、血糖(p = 0.025)、c反应蛋白(p = 0.016)显著增加,高密度脂蛋白胆固醇(p = 0.012)和总胆固醇(p = 0.042)降低,颈动脉内膜-中膜平均厚度(p = 0.012)和最大厚度(p = 0.024)增加。结论该方案可有效降低肥胖指标和动脉粥样硬化早期直接信号内膜-中膜厚度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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