Perspectives in Medicine最新文献_第7页

Breath holding index and arterial stiffness in evaluation of stroke risk in diabetic patients 屏气指数和动脉僵硬度对糖尿病患者卒中风险的评价

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.042

Iris Zavoreo, Vanja Bašić Kes, Lejla Ćorić, Vida Demarin

{"title":"Breath holding index and arterial stiffness in evaluation of stroke risk in diabetic patients","authors":"Iris Zavoreo, Vanja Bašić Kes, Lejla Ćorić, Vida Demarin","doi":"10.1016/j.permed.2012.02.042","DOIUrl":"10.1016/j.permed.2012.02.042","url":null,"abstract":"<div><h3>Background</h3><p>The aim of the study was to evaluate correlation of breath holding index (BHI) as functional parameter for intracranial subclinical atherosclerotic changes – we have shown in our previous works and arterial stiffness (AS – functional parameter for extracranial subclinical atherosclerotic changes) in diabetic patients with well and poor controlled glucose blood values in correlation with healthy population.</p></div><div><h3>Patients and methods</h3><p>We included 60 volunteers divided into 3 aged standardized groups – healthy volunteers, patients with well controlled diabetes and patients with poor controlled diabetes. We excluded individuals with moderate and severe carotid stenosis.</p></div><div><h3>Results</h3><p>There was decreasing trend in BHI values and increasing trend in AS values in diabetic patients, especially with poor regulated blood glucose values (<em>r</em>  <0.05).</p></div><div><h3>Conclusion</h3><p>These results show that decline in BHI as parameter for intracranial microvessel dysfunction is in good correlation with increase of AS as functional parameter of extracranial vascular aging in diabetic patients.</p></div>","PeriodicalId":101010,"journal":{"name":"Perspectives in Medicine","volume":"1 1","pages":"Pages 156-159"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90081929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Current trends in sonothrombolysis for acute ischemic stroke 急性缺血性脑卒中超声溶栓治疗的最新趋势

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.035

Andrei V. Alexandrov

引用次数: 2

“A horse, a horse, my kingdom for a horse” – Saddle thrombosis of carotid bifurcation in acute stroke “一匹马，一匹马，我的王国为一匹马”——急性中风患者颈动脉分叉鞍状血栓形成

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.001

Edoardo B. Vicenzini , Maria Fabrizia Giannoni , Maria Chiara Ricciardi , Gaia Sirimarco , Massimiliano Toscano , Gian Luigi Lenzi , Vittorio Di Piero

{"title":"“A horse, a horse, my kingdom for a horse” – Saddle thrombosis of carotid bifurcation in acute stroke","authors":"Edoardo B. Vicenzini , Maria Fabrizia Giannoni , Maria Chiara Ricciardi , Gaia Sirimarco , Massimiliano Toscano , Gian Luigi Lenzi , Vittorio Di Piero","doi":"10.1016/j.permed.2012.02.001","DOIUrl":"10.1016/j.permed.2012.02.001","url":null,"abstract":"<div><h3>Background</h3><p>Saddle thrombosis is less frequently detected in carotid arteries than in peripheral arterial embolism. The clot and the distal vessel patency have to be promptly recognized in these cases, because if the carotid vessel is open distally, chances may arise for successful emergent surgical procedures to remove the thrombus. At conventional static imaging, mobile floating thrombi may be difficult to differentiate from thrombosis on carotid complicated lesions of atherosclerotic origin. High-resolution ultrasound (US), with its unique capability of real-time imaging, adds fundamental data for interpretation of the findings.</p></div><div><h3>Methods</h3><p>Carotid ultrasound has been performed in acute stroke patients with high-resolution probes. Real-time clips are analyzed and imaging is presented.</p></div><div><h3>Results</h3><p>Saddle carotid bifurcation thrombosis of cardiac origin has been identified in 2 patients with acute homolateral ischemic stroke, with prompt successful surgical removal in one case. Moreover, an example of a thrombus attached on the ruptured surface of a complicated atherosclerotic plaque in an acute symptomatic stroke patient that was successfully operated in emergency is presented.</p></div><div><h3>Conclusions</h3><p>Early high-resolution ultrasound with real-time imaging can easily identify peculiar characteristics of carotid vulnerable diseases in acute stroke phase. Different clinical implications result from the early identification of these different conditions, modifying the therapeutical strategies.</p></div>","PeriodicalId":101010,"journal":{"name":"Perspectives in Medicine","volume":"1 1","pages":"Pages 435-439"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76279313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Semantic aphasia in a sonothrombolysed patient. A treatment without use of rt-PA 超声溶栓患者的语义性失语。不使用rt-PA的治疗

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/J.PERMED.2012.03.018

M. Klissurski, E. Vavrek, Nelly Nicheva-Vavrek

引用次数: 0

Comparative in vivo and in vitro postmortem ultrasound assessment of intima-media thickness with additional histological analysis in human carotid arteries 比较人颈动脉内-中膜厚度的体内和体外死后超声评估和附加的组织学分析

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.050

Szabolcs Farkas , Sándor Molnár , Katalin Nagy , Tibor Hortobágyi , László Csiba

{"title":"Comparative in vivo and in vitro postmortem ultrasound assessment of intima-media thickness with additional histological analysis in human carotid arteries","authors":"Szabolcs Farkas , Sándor Molnár , Katalin Nagy , Tibor Hortobágyi , László Csiba","doi":"10.1016/j.permed.2012.02.050","DOIUrl":"10.1016/j.permed.2012.02.050","url":null,"abstract":"<div><p>The present study aims to validate the technique of <em>in vitro</em> ultrasonography (US) by comparative analysis of premortem intima–media thickness (IMT), postmortem IMT and average wall thickness. <em>In vivo</em> common carotid artery (CCA) IMT was measured bilaterally in 25 patients at 30mm proximal from the flow divider. After autopsy <em>in vitro</em> US was performed and postmortem IMT was measured at the same level. Snap frozen arterial specimens were processed for average wall thickness determination and for histology. High degree of correlation was found between <em>in vivo</em> IMT, <em>in vitro</em> IMT and average wall thickness. Our results demonstrate: (1) <em>in vitro</em> US is a reliable and reproducible tool for the examination of autopsied arterial specimens to obtain valuable information about vascular wall properties and to identify the optimal vascular segment for tissue sampling; (2) snap freezing and cryosectioning of <em>in toto</em> excised arterial specimens is recommended for comparative histological–US studies.</p></div>","PeriodicalId":101010,"journal":{"name":"Perspectives in Medicine","volume":"1 1","pages":"Pages 170-176"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91146303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

The association of carotid intima-media thickness (cIMT) and stroke: A cross sectional study 颈动脉内膜-中膜厚度(cIMT)与脑卒中的关系:一项横断面研究

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.04.007

Salim Harris

引用次数: 11

Ipsilateral evaluation of the transverse sinus: Transcranial color-coded sonography approach in comparison with magnetic resonance venography 同侧横窦的评价:经颅彩色编码超声方法与磁共振静脉造影的比较

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.007

Marialuisa Zedde , Giovanni Malferrari , Gianni De Berti , Massimo Maggi

{"title":"Ipsilateral evaluation of the transverse sinus: Transcranial color-coded sonography approach in comparison with magnetic resonance venography","authors":"Marialuisa Zedde , Giovanni Malferrari , Gianni De Berti , Massimo Maggi","doi":"10.1016/j.permed.2012.02.007","DOIUrl":"10.1016/j.permed.2012.02.007","url":null,"abstract":"<div><h3>Introduction</h3><p>The ultrasound examination of intracranial venous structures by transcranial color-coded sonography (TCCS) is a validated and standardized application. Similarly some intracranial venous sinuses are known for their relatively low insonation rate, as straight sinus (SRS) and transverse sinus (TS), ranging from 35% to 73%. The relatively high frequency of hypoplasia of TS can partially take account for these data. The aim of this study is to evaluate the feasibility of this approach in a standard TCCS examination, in comparison with magnetic resonance (MR) findings by using the Virtual Navigator system.</p></div><div><h3>Patients and methods</h3><p>The standardized approach to the TS was a contralateral insonation, starting to the SRS plane and angulating downwards the probe. In this way it is possible to insonate the proximal segment of the contralateral TS. We proposed a new approach with an extreme downwards tilting and a slow opposite angulation of the probe for examining the ispilateral TS. Forty consecutive subjects were chosen among patients who underwent standard TCCS examinations at our lab and had a suitable temporal acoustic window, and a recently performed MR venography. The contralateral TS insonation rate was compared with the ipsilateral one.</p></div><div><h3>Results and discussion</h3><p>The insonation rate was 61/80 (76.25%) for the contralateral TS and 75/80 (93.75%) for the ipsilateral approach. Two of 5 not detectable TS were aplasic in MR venography and the others were not identified by a poor acoustic window.</p></div><div><h3>Conclusions</h3><p>The ipsilateral approach could be associated to the contralateral standard study for insonating the TS.</p></div>","PeriodicalId":101010,"journal":{"name":"Perspectives in Medicine","volume":"1 1","pages":"Pages 390-394"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81214950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

An increased frequency of right-to-left shunt in patients with chronic hyperventilation syndrome 慢性过度通气综合征患者右至左分流频率增加

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.027

Jacek Staszewski , Kazimierz Tomczykiewicz , Bogdan Brodacki , Renata Anna Piusińska-Macoch , Adam Stępień , Z. Podgajny , P. Smużyński , Maciej Zarębiński

引用次数: 2

Cerebral autoregulation in acute ischemic stroke 急性缺血性脑卒中中的大脑自我调节

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.028

Matthias Reinhard , Sebastian Rutsch , Andreas Hetzel

{"title":"Cerebral autoregulation in acute ischemic stroke","authors":"Matthias Reinhard , Sebastian Rutsch , Andreas Hetzel","doi":"10.1016/j.permed.2012.02.028","DOIUrl":"10.1016/j.permed.2012.02.028","url":null,"abstract":"<div><p>Cerebral autoregulation is particularly challenged in acute ischemic stroke. In this review we summarize the data of our previous studies on autoregulation regarding the effect of rtPA on autoregulation after stroke. A pooled analysis of two studies (45 patients) has shown a worsening of the autoregulatory index Mx between an early (first 48h) and late (days 5–7) measurement. This increase was more pronounced on affected sides than on unaffected sides. Poor ipsilateral Mx was associated with a greater volume of MCA infarction at a late measurement and related to poor clinical outcome. Overall, autoregulatory impairment tends to increase mainly in large infarction and generalize to the contralateral side during the first days after ischemic stroke. As a limitation, transcranial Doppler sonography does not allow to detect focal areas of dysautoregulation in smaller strokes. To better understand the temporal and spatial dynamics of dysautoregulation in acute stroke in relation to the type and size of infarction, new bedside hemodynamic monitoring techniques (like multi-channel near-infrared spectroscopy) are needed.</p></div>","PeriodicalId":101010,"journal":{"name":"Perspectives in Medicine","volume":"1 1","pages":"Pages 194-197"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76519511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Post-carotid stent ultrasound provides critical data to avoid rare but serious complications 颈动脉支架后超声为避免罕见但严重的并发症提供了关键数据

Perspectives in Medicine Pub Date : 2012-09-01 DOI: 10.1016/j.permed.2012.02.019

John J. Volpi , Zsolt Garami , Rasadul Kabir , Orlando Diaz-Daza , Richard Klucznik

引用次数: 0