I. Alajbeg , V. Vucicevic Boras , R. Femenic , A. Cekic-Arambasin , M. Anicic , J. Kelecic , I.Z. Alajbeg
{"title":"Unrecognized oral manifestations of Langerhans cell histiocytosis which progressed to systemic disease","authors":"I. Alajbeg , V. Vucicevic Boras , R. Femenic , A. Cekic-Arambasin , M. Anicic , J. Kelecic , I.Z. Alajbeg","doi":"10.1016/j.ooe.2005.07.012","DOIUrl":"10.1016/j.ooe.2005.07.012","url":null,"abstract":"<div><p>A 2.5 years old boy was referred to the Department of oral medicine because of substantial erythema and ulcerations on palatal, buccal and alveolar regions. Unfortunately, it took two subsequent visits to our Department in six-months intervals, and re-evaluation at Pediatric oncology clinic where diagnosis of Langerhans cell histiocytosis (LCH) was finally established. At that stage, disease already progressed to multisystem life-threatening presentation, requiring aggressive treatment. Therefore, this case is a reminder of the possibility of occurrence of this rare disease in the oral cavity which might manifest itself in multiple presentations thus easily leading to the misdiagnosis and therefore it could be easily overlooked by dentists.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 10-13"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.07.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77163441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Ries Centeno , F. Nadini , R. Adam , H. Godoy , P.A. Reichart
{"title":"Primary leiomyosarcoma of the mandible","authors":"C. Ries Centeno , F. Nadini , R. Adam , H. Godoy , P.A. Reichart","doi":"10.1016/j.ooe.2005.08.008","DOIUrl":"10.1016/j.ooe.2005.08.008","url":null,"abstract":"<div><p>Leiomyosarcoma (LMS) is a malignant neoplasm derived from smooth muscle cells. Only between 3% and 10% appear in the head and neck region, and less than 1% is of intraoral location affecting oral soft tissue structures. About 20 cases of primary LMS involving the mandible have been reported. This case report describes the clinical, histological and surgical features of a primary intraosseous mandibular LMS in a 13 year old male patient. The tumour required a subtotal resection of the mandible with immediate reconstruction using a microsurgical fibula flap. Histopathologically, the characteristic features of leiomyosarcoma were revealed. Since the total number of cases of primary LMS of the mandible reported in the literature is very small factors associated with prognosis are difficult to evaluate. Local control of primary LMS of the mandible is achieved by adequate radical surgery and less by radiation therapy.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 40-45"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.08.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76168530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral squamous cell carcinoma with discoid lupus erythematosus","authors":"N.W. Savage, V. Vucicevic Boras, Z. Mohamad Zaini","doi":"10.1016/j.ooe.2005.08.006","DOIUrl":"10.1016/j.ooe.2005.08.006","url":null,"abstract":"<div><p>This paper reports an interesting development in a 64 year old female originally referred for evaluation of oral lichenoid lesions. The patient had a previous diagnosis of discoid lupus erythematosus of the skin. The presenting oral clinical appearance varied between lichenoid areas and ectopic erythema migrans. At initial presentation the patient had an exophytic lesion on the vermilion of the lower lip and biopsy confirmed the clinical diagnosis of oral squamous cell carcinoma. She subsequently developed multiple lesions involving isolated oral sites as well as the lip.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 32-35"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.08.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76748355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thalidomide in the concurrent management of recurrent aphthous ulcerations and Kaposi sarcoma in HIV patients with severe immunosuppression","authors":"Kishore Shetty","doi":"10.1016/j.ooe.2005.08.005","DOIUrl":"10.1016/j.ooe.2005.08.005","url":null,"abstract":"<div><p>Thalidomide is a complex immunomodulatory and antiangiogenic agent whose role in oncology practice is as yet not fully clear. We present an unusual case documenting the use of thalidomide in the concurrent management of recurrent aphthous ulceration and kaposi sarcoma in a patient with severe immmunosuppression.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 26-31"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.08.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83341245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shubha Sharma , Phulkumari Talukdar , Basant M. Singhal , Jayesh A. Prajapati , Jignesh V. Goswami , Jayesh J. Patel , Devendra D. Patel
{"title":"Haemangiopericytoma—base of tongue","authors":"Shubha Sharma , Phulkumari Talukdar , Basant M. Singhal , Jayesh A. Prajapati , Jignesh V. Goswami , Jayesh J. Patel , Devendra D. Patel","doi":"10.1016/j.ooe.2005.02.005","DOIUrl":"10.1016/j.ooe.2005.02.005","url":null,"abstract":"<div><p>Haemangiopericytoma is a rare vascular neoplasm arising from pericytes in the walls of the capillaries and venules. This tumor is reported to occur mostly in lower extremity and retro peritoneum with rare occurrence in the head and neck region. Generally they are slow growing, locally infiltrative and aggressive, with various rates of pleomorphism and malignant potential. Clinical presentations of these tumors are characteristically non-specific and diagnostic modalities are of little help. Surgery remains the gold standard of the treatment with additional benefits if adjuvant RT is taken. Here we report a case of haemangiopericytoma arising in the base of the tongue with a brief review of the literature. To our knowledge this is the first case in this location to be reported in the English literature.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.02.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85720061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly R. Magliocca, Matthew K. Rand, Lyndon D. Su, Joseph I. Helman
{"title":"Melanoma-in-situ of the oral cavity","authors":"Kelly R. Magliocca, Matthew K. Rand, Lyndon D. Su, Joseph I. Helman","doi":"10.1016/j.ooe.2005.08.009","DOIUrl":"10.1016/j.ooe.2005.08.009","url":null,"abstract":"<div><p>A pigmented lesion of the oral cavity should be viewed with suspicion since melanoma of the oral cavity is often asymptomatic in its early stages and often is diagnosed after it has invaded. In this particular case, astute observation and a prompt referral led to a diagnosis of oral melanoma-in-situ in the anterior palate and its successful treatment.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 46-48"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.08.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79986824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter A. Reichart , Hans Peter Philipsen , Alexander Moegelin , Uwe Thalmann
{"title":"Central odontogenic fibroma, granular cell variant","authors":"Peter A. Reichart , Hans Peter Philipsen , Alexander Moegelin , Uwe Thalmann","doi":"10.1016/j.ooe.2005.05.007","DOIUrl":"10.1016/j.ooe.2005.05.007","url":null,"abstract":"<div><p>A case of central odontogenic fibroma (COF) of the <em>epithelium-rich</em> type (granular cell variant) is reported. A 46-year-old female, demonstrated a multilocular, septated radiolucency below and between the roots of the teeth in 44–47 region. On microscopy the lesion revealed an odontogenic fibroma of the <em>epithelium-rich</em> type with areas characterized by lobules of spherical cells of varying size containing fine S-100 negative granules. In addition, scattered foci of cementoid/osteoid calcified material occurred. Based on several studies, the present authors entertain the hypothesis that supports a histiocystic origin the granular cells. Therapy consisted of curettage of the lesion. The defect was filled with spongeous bone. No recurrence occurred after follow-up of two years.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 5-9"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.05.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76936325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Giant ameloblastoma of jaw successfully treated by radiotherapy","authors":"Rastogi Madhup , Srivastava Kirti , M.L.B. Bhatt , M. Srivastava , Singh Sudhir , A.N. Srivastava","doi":"10.1016/j.ooe.2005.08.004","DOIUrl":"10.1016/j.ooe.2005.08.004","url":null,"abstract":"<div><p>Ameloblastomas are uncommon tumors, which were thought to be radioresistant. However there is lack of well-documented evidence in the literature concerning their relative radio responsiveness or radio resistance nature. The present article reports a case of ameloblastoma of jaw, successfully treated by radiotherapy.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 22-25"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89488583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disseminated oral Kaposi sarcoma lesion with extensive visceral involvement","authors":"Kishore Shetty","doi":"10.1016/j.ooe.2005.08.003","DOIUrl":"10.1016/j.ooe.2005.08.003","url":null,"abstract":"<div><p>Kaposi’s sarcoma (KS) has been considered the most common malignancy associated with human immunodeficiency virus (HIV) infection because of its propensity to develop in such individuals.This article, reports an unusual presentation of a disseminated oral KS lesion with extensive visceral involvement in an otherwise healthy young African-American male leading to a positive diagnosis of HIV.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 18-21"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88987214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leiomyosarcoma of the oral cavity: Report of seven cases and review of literature","authors":"H. Amarapala , W.M. Tilakaratne","doi":"10.1016/j.ooe.2005.08.001","DOIUrl":"10.1016/j.ooe.2005.08.001","url":null,"abstract":"<div><p>Leiomyosarcoma is a relatively uncommon tumor that exhibits smooth muscle differentiation. Occurrence of this neoplasm in the oral cavity is exceedingly rare. Presenting signs and symptoms of leiomyosarcoma in the oral region are generally non-specific. The tumour is commonly encountered as a slow growing, discreet firm, and non-ulcerated painless mass. The physical appearance of these tumors can be deceptively benign and can also be mistaken for non-malignant conditions. Due to its innocuous clinical presentation and similarity to certain benign lesions it is critical for the dental surgeon to be familiar with this unusual lesion, as early diagnosis and aggressive initial treatment remains the mainstay of therapy for a good prognosis. This article presents seven cases of primary leiomyosarcoma in the oral region and highlights the need for early prudent diagnosis and treatment, without which may lead to a very poor out come of ill-fated patients.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 14-17"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86571370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}