Peter A. Reichart , Hans Peter Philipsen , Alexander Moegelin , Uwe Thalmann
{"title":"Central odontogenic fibroma, granular cell variant","authors":"Peter A. Reichart , Hans Peter Philipsen , Alexander Moegelin , Uwe Thalmann","doi":"10.1016/j.ooe.2005.05.007","DOIUrl":null,"url":null,"abstract":"<div><p>A case of central odontogenic fibroma (COF) of the <em>epithelium-rich</em> type (granular cell variant) is reported. A 46-year-old female, demonstrated a multilocular, septated radiolucency below and between the roots of the teeth in 44–47 region. On microscopy the lesion revealed an odontogenic fibroma of the <em>epithelium-rich</em> type with areas characterized by lobules of spherical cells of varying size containing fine S-100 negative granules. In addition, scattered foci of cementoid/osteoid calcified material occurred. Based on several studies, the present authors entertain the hypothesis that supports a histiocystic origin the granular cells. Therapy consisted of curettage of the lesion. The defect was filled with spongeous bone. No recurrence occurred after follow-up of two years.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 1","pages":"Pages 5-9"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.05.007","citationCount":"23","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Oncology Extra","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1741940905000427","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 23
Abstract
A case of central odontogenic fibroma (COF) of the epithelium-rich type (granular cell variant) is reported. A 46-year-old female, demonstrated a multilocular, septated radiolucency below and between the roots of the teeth in 44–47 region. On microscopy the lesion revealed an odontogenic fibroma of the epithelium-rich type with areas characterized by lobules of spherical cells of varying size containing fine S-100 negative granules. In addition, scattered foci of cementoid/osteoid calcified material occurred. Based on several studies, the present authors entertain the hypothesis that supports a histiocystic origin the granular cells. Therapy consisted of curettage of the lesion. The defect was filled with spongeous bone. No recurrence occurred after follow-up of two years.
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