Nano Trends最新文献_第10页

Recent trends in graphene based transition metal oxides as anode materials for rechargeable lithium-ion batteries 石墨烯基过渡金属氧化物作为可充电锂离子电池阳极材料的最新趋势

Nano Trends Pub Date : 2023-03-01 DOI: 10.1016/j.nwnano.2023.100004

Kefayat Ullah , Noreen Shah , Reshma Wadood , Bakht Mand Khan , Won Chun Oh

{"title":"Recent trends in graphene based transition metal oxides as anode materials for rechargeable lithium-ion batteries","authors":"Kefayat Ullah , Noreen Shah , Reshma Wadood , Bakht Mand Khan , Won Chun Oh","doi":"10.1016/j.nwnano.2023.100004","DOIUrl":"https://doi.org/10.1016/j.nwnano.2023.100004","url":null,"abstract":"<div><p>The world is looking for the production of smart and green energy from fossils and renewable energy resources. In this regard the production and storage are the key factor for marinating the balance in energy production and consumption. Batteries are considered to be one of the most important components in these energy resources. Presently many electronics and electric vehicles are powered by batteries. Lithium-ion batteries (LIBs) have currently faced a few limitations deterring the development in battery technologies. Lithium metals emerge recently, but highly corrosive, the catastrophic dendrites, the pressure induced in order to maintain the contact between cathode and anode etc. Though there are many new composite materials reported recently to address many of the mention issues. Recently carbon and its derivative has been found to be the best anode materials for LIBs. An attempt has been made to enhance the functionality and durability of LIBs, because their pervasiveness is expected to rise. In this review we consider transition metal oxides with graphene as anode material and discussed various development towards the fabrication of LIBs. Researchers have demonstrated that a particular graphene composite can be added to the anode of LIBs to dramatically improve its operational stability, allowing for the development of significantly more potent, long-lasting LIBs.</p></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"1 ","pages":"Article 100004"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50178907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Nano based photodynamic therapy to target tumor microenvironment 靶向肿瘤微环境的纳米光动力疗法

Nano Trends Pub Date : 2023-03-01 DOI: 10.1016/j.nwnano.2023.100003

Venkateshwaran Krishnaswami , Balakrishnan Natarajan , Vaidevi Sethuraman , Subramanian Natesan , Brito RajSelvaraj

引用次数: 1

Nano-formulated siRNA-based therapeutic approaches for cancer therapy 用于癌症治疗的基于纳米siRNA的治疗方法

Nano Trends Pub Date : 2023-03-01 DOI: 10.1016/j.nwnano.2023.100006

Dolly Jain , Shiv Kumar Prajapati , Ankit Jain , Rohit Singhal

{"title":"Nano-formulated siRNA-based therapeutic approaches for cancer therapy","authors":"Dolly Jain , Shiv Kumar Prajapati , Ankit Jain , Rohit Singhal","doi":"10.1016/j.nwnano.2023.100006","DOIUrl":"https://doi.org/10.1016/j.nwnano.2023.100006","url":null,"abstract":"<div><p>RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a homologous mRNA sequence in the cell. However, the limited potential of siRNA delivery to target cells, poor cellular uptake, off-target effect, and their breakdown by serum nucleases in systemic circulation are limiting factors for their therapeutic applications. Over the past few years, siRNA drugs are undergoing a period of clinical translation. Therefore, this review mainly highlights the state-of-the-art of nanocarriers for delivering siRNA cargos and their coadministration with anticancer drugs, along with their applications in cancer treatment. Besides, molecular manifestations, challenges in the delivery of siRNA, design, and development of siRNA-based delivery systems, merits, and demerits of different nanocarriers have been discussed. The endosomal trapping of siRNA is a major difficulty for most delivery strategies, influencing the therapeutic effect. To address this issue various approaches for siRNA release including pH-responsive release, membrane fusion, proton sponge effect, and photochemical disruption have been discussed. Finally, the current status of siRNA therapeutics in clinical trials is explored, providing a systematic and comprehensive overview of siRNA-based therapeutics for effective cancer treatment.</p></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"1 ","pages":"Article 100006"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50177979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Transport of nanocarriers to brain for treatment of glioblastoma multiforme: Routes and challenges 纳米载体转运至大脑治疗多形性胶质母细胞瘤：途径和挑战

Nano Trends Pub Date : 2023-03-01 DOI: 10.1016/j.nwnano.2023.100005

Sagar Trivedi, Vidyadevi Bhoyar, Natasha Akojwar, Veena Belgamwar

{"title":"Transport of nanocarriers to brain for treatment of glioblastoma multiforme: Routes and challenges","authors":"Sagar Trivedi, Vidyadevi Bhoyar, Natasha Akojwar, Veena Belgamwar","doi":"10.1016/j.nwnano.2023.100005","DOIUrl":"https://doi.org/10.1016/j.nwnano.2023.100005","url":null,"abstract":"<div><p>Glioblastoma Multiforme (GBM) is one of the most infiltrative, heterogenous types of brain malignancies and is mainly associated with poor prognosis. Despite various advances in treatment regimens, conventional therapies fall short of enhancing the average life expectancy of patients. This may be mainly subjected to insufficiency of chemotherapeutics reaching the target site because of various biological barriers including the blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB). Furthermore, to overcome such barriers nanocarriers have assisted proven to be advantageous as they enhance the bioavailability of drugs by improving blood retention time, reducing toxicity, and site-specific targeting. Internalization of nanocarriers in cells occurs via various mechanisms and aids in crossing biological barriers. Irrespective of the type of nanocarrier route of administration also has a vital role which mainly aims at providing higher bioavailability and patient compliance. Hence this review deals with various aspects relating to the transport of nanocarriers to the brain and their routes of administration for the treatment of GBM.</p></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"1 ","pages":"Article 100005"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50178434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1