Journal of Pediatric Surgery Open最新文献

{"title":"Analgesia in pediatric abdominal surgery","authors":"Jan Geudens ,&nbsp;An Teunkens","doi":"10.1016/j.yjpso.2025.100199","DOIUrl":"10.1016/j.yjpso.2025.100199","url":null,"abstract":"<div><div>Adequate analgesia is a key component of pediatric abdominal surgery. Multimodal analgesia, using different pharmacological products and locoregional techniques, is increasingly used in clinical practice.</div><div>This study aims to provide a clear overview of the different modalities used in abdominal surgery in the pediatric population. We conducted a literature review in which relevant articles, which focused on the efficacy, side effects, and locoregional techniques of pharmacological products, were included and analyzed.</div><div>The combined use of classic analgesics (such as paracetamol and nonsteroidal anti-inflammatory drugs) or alpha-2 agonists together with opioids can ensure lower opioid use, which in turn reduces the risk of adverse effects. Various locoregional techniques, particularly the transversus abdominis plane block and quadratus lumborum block, have also been shown to be effective in abdominal surgery in the pediatric population. Age-specific differences in analgesic use were investigated, with the importance of correct weight-based dosing and proper monitoring of vital parameters being particularly crucial. Further research focusing on specific surgical procedures could identify the most indicated technique.</div><div>In conclusion, sufficient evidence supports the use of multimodal analgesia as the standard approach in pediatric abdominal surgery.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"10 ","pages":"Article 100199"},"PeriodicalIF":0.0,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prepubertal testicular tumors: Clinical characteristics and indications for testis-sparing surgery in a multicenter retrospective study","authors":"Shojiro Hanaki ,&nbsp;Shuichi Katayama ,&nbsp;Yasuo Nakahara ,&nbsp;Soichi Nakada ,&nbsp;Kohsuke Hitomi ,&nbsp;Takeshi Asai ,&nbsp;Shuichi Ishibashi ,&nbsp;Tsutomu Kanagawa ,&nbsp;Koji Aoyama","doi":"10.1016/j.yjpso.2025.100197","DOIUrl":"10.1016/j.yjpso.2025.100197","url":null,"abstract":"<div><h3>Objectives</h3><div>We aimed to clarify the characteristics of prepubertal testicular tumors and evaluate the suitability of testis-sparing surgery (TSS) for benign prepubertal testicular tumors, with a focus on clinical outcomes and tumor-specific factors that influence treatment decisions.</div></div><div><h3>Methods</h3><div>A retrospective study was conducted involving 34 patients under 14 years of age who were treated for testicular tumors at five institutions from 2001 to 2021. Clinical parameters were compared between benign and malignant groups, and additional parameters, such as testicular volume, tumor volume, and tumor volume ratio, were analyzed within the benign group.</div></div><div><h3>Results</h3><div>There were 18 cases in the benign group and 16 in the malignant group. The maximal tumor diameter was significantly larger in the malignant group (2.0 cm vs. 3.5 cm, <em>p</em> = 0.006). In the benign group, all cases in the TSS group had a tumor volume ratio &lt; 70 % and a maximal tumor diameter ≤ 2 cm (<em>p</em> = 0.006). No cases of testicular atrophy or recurrence were observed during a median follow-up of 60 months in the benign group.</div></div><div><h3>Conclusions</h3><div>TSS is a feasible option for benign prepubertal testicular tumors with favorable preoperative evaluation results, offering preservation of testicular function without compromising oncological safety. Parameters such as a maximal tumor diameter ≤ 2 cm and a tumor volume ratio &lt; 70 % may help determine the suitability of TSS and support clinical decision-making in pediatric testicular surgery.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"10 ","pages":"Article 100197"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Getting children home sooner on intravenous antibiotics with a Hospital-in-the-Home model of care for complicated appendicitis","authors":"Ling Chen ,&nbsp;Sebastian K. King ,&nbsp;Misel Trajanovska ,&nbsp;Lynda M. Gaynor ,&nbsp;Veronica Cerratti ,&nbsp;Rosemary Burgess ,&nbsp;Gregory J.G. Nolan ,&nbsp;Warwick J. Teague ,&nbsp;Penelope A. Bryant","doi":"10.1016/j.yjpso.2025.100196","DOIUrl":"10.1016/j.yjpso.2025.100196","url":null,"abstract":"<div><div>Children with complicated appendicitis requiring prolonged intravenous antibiotics could complete their treatment under Hospital-in-the-Home (HITH). Evidence is lacking in identifying suitable patients.</div></div><div><h3>Objective</h3><div>To determine the feasibility of using post-operative clinical criteria in complicated appendicitis to identify eligible patients, and assess the safety of treating HITH-suitable patients at home.</div></div><div><h3>Methods</h3><div>This was a prospective pilot study at a tertiary pediatric hospital. Children aged 5–18 years, undergoing appendicectomy, identified as having complicated appendicitis intra-operatively, with at least 5 days’ post-operative intravenous antibiotics planned. HITH suitable patients were defined clinically as tolerating diet and passing flatus before day 5.</div></div><div><h3>Interventions</h3><div>The HITH model of care was developed and piloted. HITH-suitable patients were transferred and treated via HITH.</div></div><div><h3>Main Outcome Measures</h3><div>Clinical characteristics and post-operative outcomes were measured and compared between patients treated in the hospital and patients treated at home.</div></div><div><h3>Results</h3><div>During the model development 83 patients fulfilled inclusion criteria: 35 (42 %) HITH-suitable and 48 (58 %) HITH-unsuitable. The groups were similar pre-/peri‑operatively, but post-operatively HITH-suitable patients recovered faster (median length of stay 6 versus 7 days, <em>p</em> &lt; 0.001) and had fewer complications (0 % vs 23 %, <em>p</em> = 0.001). Of the HITH-suitable group, initially 10 patients were treated on HITH and a further 15 during ongoing model assessment, totaling 25 (50 %) HITH-treated and 25 (50 %) HITH-suitable patients who remained in hospital. The HITH-treated patients spent 35 % less time in hospital, and had no increased rates of complications or re-admissions compared to suitable patients who remained in hospital.</div></div><div><h3>Conclusions</h3><div>We have defined clinical criteria that identify children for whom HITH care appears safe following surgery for complicated appendicitis. Larger studies are required to validate these findings.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"10 ","pages":"Article 100196"},"PeriodicalIF":0.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the paediatric appendicitis risk calculator (pARC) in an Australian emergency department setting","authors":"Alexander Howes ,&nbsp;Sanjeev Khurana ,&nbsp;Jennie Louise ,&nbsp;Isabella Watts ,&nbsp;Rebecca Linke ,&nbsp;Amit Kochar","doi":"10.1016/j.yjpso.2025.100192","DOIUrl":"10.1016/j.yjpso.2025.100192","url":null,"abstract":"<div><h3>Study objective</h3><div>Our objective is to assess the performance of the Paediatric Appendicitis risk calculator (pARC) in quantifying the risk of appendicitis, in an Australian tertiary emergency department (ED) and to compare its performance with that of the Paediatric Appendicitis Score (PAS) and Alvarado score in predicting risk of appendicitis.</div></div><div><h3>Methods</h3><div>We conducted this prospective, observational cohort study from July 2021 to October 2022 in the Women's and Children's Hospital (WCH) ED in Adelaide, South Australia. Patients aged 5 to 18 presenting with abdominal pain ≤120 h, where appendicitis was a differential diagnosis, were eligible for enrolment. Our primary outcome was the histopathological diagnosis of appendicitis within 14 days of initial presentation. We reported performance characteristics and secondary outcomes by pARC risk strata and compared the receiver operator characteristic (ROC) curves of the PAS, Alvarado and pARC.</div></div><div><h3>Results</h3><div>We enrolled 675 patients with a mean age of 11.93 years, 51 % were female. Appendicitis was histologically diagnosed in 29.33 % of patients, with 13.6 % having perforated appendicitis. 51 % of patients had very low (&lt;5 %) or low (5 % to 14 %) predicted risk, 40.3 % had intermediate risk (15 % to 84 %), and 6.5 % had high risk (&gt;85 %). In the very-low- and low-risk groups, 6.4 % and 11 % of patients had appendicitis, respectively. The AUROC was 0.852 (95 % confidence interval (CI) 0.820 to 0.885) for the pARC compared with 0.80 (95 % CI 0.77 to 0.84) for the PAS, and 0.73 (95 % CI 0.69, 0.78) for Alvarado.</div></div><div><h3>Conclusion</h3><div>The pARC score has been validated as an appendicitis risk calculator which is as reliable as previous studies, in the study population, whilst outperforming the PAS and Alvarado scores.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"10 ","pages":"Article 100192"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volume-outcome relationship in pediatric blunt liver and spleen injuries: A multicenter retrospective cohort study","authors":"Susumu Matsushime ,&nbsp;Akira Kuriyama ,&nbsp;Morihiro Katsura","doi":"10.1016/j.yjpso.2025.100194","DOIUrl":"10.1016/j.yjpso.2025.100194","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between the number of patients treated in a hospital and patient outcomes (“volume-outcome relationship”) has been reported. We aimed to examine the relationship between hospital case volume and complications, in-hospital mortality, and non-operative management (NOM) failure in pediatric blunt liver and/or spleen injuries (BLSIs).</div></div><div><h3>Methods</h3><div>This was a post-hoc analysis of a multicenter retrospective study that enrolled patients aged ≤16 years admitted for BLSIs with Abbreviated Injury Scale grade of at least ≥1 between January 2008 and December 2019. Participating hospitals were categorized into three groups of 33 % each, according to the annual pediatric trauma case volume. We used the Cochrane-Armitage test to determine a linear trend between the hospital case volume and each outcome.</div></div><div><h3>Results</h3><div>We identified 1406 patients with BLSIs who were treated at 83 hospitals; 44 (3.1 %) and 12 (0.9 %) patients experienced complications and NOM failure, respectively, with 21 cases (1.5 %) of in-hospital mortality. Hospitals were categorized into high- (28 hospitals), medium- (26 hospitals), and low-volume (29 hospitals) groups. No significant linear trend was observed between hospital volumes and complications (P <em>trend</em>=0.07), in-hospital mortality (P <em>trend</em>=0.67), or NOM failure (P <em>trend</em>=0.57). Sensitivity analyses using different group categorizations provided similar findings.</div></div><div><h3>Conclusions</h3><div>This study failed to confirm a volume-outcome relationship between annual pediatric trauma case volume and complications, in-hospital mortality, or NOM failure in pediatric BLSIs in Japan. The limited exposure of Japanese hospitals to pediatric trauma, lack of a system to certify pediatric trauma centers, and practice variations across hospital types potentially underlie these findings.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"10 ","pages":"Article 100194"},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open versus thoracoscopic approach in the surgical treatment of congenital pulmonary airway malformations: A retrospective cross-sectional analysis and review","authors":"Jean Dai ,&nbsp;Jesse York ,&nbsp;Baylor Schexnayder ,&nbsp;Frankie Fike","doi":"10.1016/j.yjpso.2025.100193","DOIUrl":"10.1016/j.yjpso.2025.100193","url":null,"abstract":"<div><h3>Introduction</h3><div>Congenital pulmonary airway malformations (CPAMs) are rare developmental lung abnormalities that often require surgical intervention. This study aimed to compare resource utilization and in-hospital outcomes between open thoracotomy and thoracoscopic approaches for CPAM treatment.</div></div><div><h3>Methods</h3><div>We used the Kids' Inpatient Database (KID), the largest publicly available all-payer pediatric inpatient care registry, to identify patients under 20 years old who were treated with elective surgery for CPAM in 2016 and 2019. Patients were categorized into open thoracotomy or thoracoscopic groups based on International Classification of Disease, Tenth Revision (ICD-10) procedure codes. We analyzed differences in demographic characteristics, complications, total cost of stay, and length of hospital stay between the two groups.</div></div><div><h3>Results</h3><div>The study included 749 patients (436 thoracoscopic, 313 open). Demographic analysis revealed significant differences in sex distribution (<em>p</em> = 0.028) and race (<em>p</em> &lt; 0.001) between groups. The mean age was similar (thoracoscopic: 1.2 years, open: 1.7 years; <em>p</em> = 0.059). Complications were not significantly different between approaches. The thoracoscopic approach was associated with lower mean total cost of stay ($74,719 vs. $82,146; <em>p</em> = 0.037) and shorter mean length of stay (3.1 vs. 4.5 days; <em>p</em> &lt; 0.001) compared to the open approach (Table 1).</div></div><div><h3>Conclusion</h3><div>This study suggests that the thoracoscopic approach for CPAM treatment may offer advantages in terms of reduced hospital costs and shorter length of stay without significantly increasing complication rates. These findings could inform clinical decision-making and resource allocation in pediatric surgical care. Further research is needed to assess long-term outcomes and patient-reported measures between these approaches.</div><div>Type of study: retrospective cross-sectional analysis</div><div>Level of evidence: 4</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"10 ","pages":"Article 100193"},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined surgical and interventional cardiology approach for central venous access salvage in children with intestinal failure: A case series","authors":"Emily Byrd ,&nbsp;M. Jake Petersen ,&nbsp;Minna M. Wieck ,&nbsp;Frank Ing ,&nbsp;Shinjiro Hirose","doi":"10.1016/j.yjpso.2024.100186","DOIUrl":"10.1016/j.yjpso.2024.100186","url":null,"abstract":"<div><h3>Background</h3><div>Pediatric patients with intestinal failure are critically dependent on central venous access for nutrition and fluids. Long-term central venous access can be complicated by recurrent infections, catheter malfunction, and venous stricture and thrombosis. Prior studies have discussed hybrid procedures to salvage suboptimal central venous access sites; however, data is very limited.</div></div><div><h3>Methods</h3><div>This is a retrospective review of six pediatric patients with intestinal failure (IF) and long-term total parenteral nutrition (TPN) dependence who underwent one or more hybrid procedures for achieving complex vascular access, vascular mapping, and/or salvage of vascular access sites.</div></div><div><h3>Results</h3><div>Median age at the time of intervention was 1.4 years (range 2.5 weeks – 2.6 years) with a median weight of 10 kg (range 3.3–13.8 kg). The median number of lifetime central lines was 4 (range 2–6). Indications for hybrid intervention included line fractures, occlusions, dislodgement, recurrent infections, and refractory central line infection. The most common procedures included vascular access, vein mapping, and balloon angioplasty of occluded central veins. The median procedure time was 4.6 h (range 1.3–5.9 h) with a median procedural radiation dose of 2.2 Gycm² (range 0.1–6.7 Gycm²). All patients who underwent hybrid procedures had successful exchange and/or rehabilitation of the at-risk access site.</div></div><div><h3>Conclusions</h3><div>These cases highlight the importance of vascular mapping for identifying potential access sites, as well as techniques for successful vascular rehabilitation for maintenance or salvage of existing central venous access. A multidisciplinary hybrid approach is a feasible and effective means of maintaining central venous access.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"9 ","pages":"Article 100186"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early removal of indwelling urinary catheters in children undergoing abdominal tumor resection with epidural analgesia","authors":"Shachi Srivatsa ,&nbsp;Jennifer H. Aldrink ,&nbsp;Dana Schwartz ,&nbsp;Grant Heydinger ,&nbsp;Andrew Davidoff ,&nbsp;Andrew J. Murphy ,&nbsp;Kyle O. Rove ,&nbsp;Sara A. Mansfield","doi":"10.1016/j.yjpso.2024.100191","DOIUrl":"10.1016/j.yjpso.2024.100191","url":null,"abstract":"<div><h3>Purpose</h3><div>Epidural analgesia (EA) is commonly employed for postoperative pain management in children undergoing abdominal tumor resection. Indwelling urinary catheters (IUCs) often remain for the duration of EA administration due to concern for associated urinary retention. This study focuses on children undergoing abdominal tumor resection with appropriate EA coverage, to assess whether IUC can be removed early with minimal risk of reinsertion for urinary retention.</div></div><div><h3>Methods</h3><div>A retrospective review of children who underwent abdominal tumor resections with EA between 2015 and 2023 at two institutions was conducted. Data were summarized, and rates of postoperative urinary retention requiring catheter reinsertion and catheter-associated urinary tract infections (CAUTIs) were compared between patients with early and late IUC removal groups using Fisher's exact testing. “Early” was defined as IUC removal with EA in place and “late” as IUC removal after or concurrent with EA discontinuation.</div></div><div><h3>Results</h3><div>A total of 228 children underwent abdominal tumor resections with EA. Of these, 104 had early, and 124 had late IUC removal. The average postoperative day (POD) of IUC removal in the early group was 1.1±0.5 days and 2.9±1.1 days in the late group. EA was at T12 level or higher in 101 patients (97.1 %) in the early group, and 68 (54.8 %) in the late group (p&lt;0.001). EA contained opioids in 27 (26.0 %) in the early group and 54 (43.5 %) in the late group (p=0.005). There were 6 (5.8 %) children in the early group and 1 (0.8 %) in the late group requiring re-catheterization (p = 0.049). For those requiring re-catheterization, the EA level was T7-8 in 5 patients, T10-11 in 1 patient, and T4 in 1 patient (late). There was 1 (1.0 %) patient with a CAUTI in the early group, and 3 (2.4 %) patients in the late group (p = 0.63).</div></div><div><h3>Conclusions</h3><div>Early removal of indwelling urinary catheters in the setting of thoracic epidural analgesia is associated with a small risk of urinary retention necessitating catheter re-insertion. Balancing the need for IUCs with this possibility, patient comfort, and infectious risk should inform decision-making to best align with enhanced recovery efforts.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"9 ","pages":"Article 100191"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional outcomes following injury in pediatric patients without traumatic brain injury","authors":"Ryo Yamamoto ,&nbsp;Lillian Liao ,&nbsp;Keitaro Yajima ,&nbsp;Akira Endo ,&nbsp;Kazuma Yamakawa ,&nbsp;Junichi Sasaki","doi":"10.1016/j.yjpso.2024.100183","DOIUrl":"10.1016/j.yjpso.2024.100183","url":null,"abstract":"<div><h3>Background</h3><div>Pediatric trauma patients often have disability after successful resuscitation for hemorrhage. Clinical characteristics related to dependency on living following injury were elucidated among pediatric patients without traumatic brain injury.</div></div><div><h3>Methods</h3><div>This retrospective cohort study used the 2019–2021 Japan Trauma Data Bank and included pediatric patients aged ≤16 years without head injury (Abbreviated Injury Scale [AIS] ≥ 2). The unfavorable function was defined as dependency in daily life at discharge (Glasgow Outcome Scale ≤ 3), and predictors for unfavorable functional outcomes were examined using a generalized estimating equations (GEE) model, including age, sex, physical disability before injury, injury mechanism, transportation time, prehospital procedures, vital signs on arrival, surgery in each body region, transfusion, AIS in each region, and institutions. Furthermore, these factors were analyzed separately in toddler/preschool (≤5 years), school age (6–11 years), and adolescence (12–16 years).</div></div><div><h3>Results</h3><div>Among 1,412 patients eligible for the study, 137 had an unfavorable physical function at discharge. The GEE model revealed that female sex, physical disability before injury, prehospital transfusion, lower Glasgow Coma Score (GCS) score on arrival, neck surgery, and higher AIS in the neck and extremity/pelvis were independently associated with unfavorable function at discharge. In age-specific analyses, physical disability before injury strongly predicted worse functional outcomes in toddlers/preschoolers, whereas higher AIS in the chest and lower systolic blood pressure on arrival were additional predictors of dependent living among adolescents.</div></div><div><h3>Conclusions</h3><div>Severe neck/extremity/pelvis injury and lower GCS on arrival are associated with unfavorable functional outcomes in patients with pediatric trauma.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"9 ","pages":"Article 100183"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Mesenchymal Stem Cells Attenuates Hirschsprung diseases-Associated Enterocolitis by Reducing M1 Macrophages Infiltration via COX-2 Dependent Mechanism” [J Pediatr Surg 59 (2024) 1498–1514]","authors":"Xinyao Meng ,&nbsp;Jun Xiao ,&nbsp;Jing Wang ,&nbsp;Minxian Sun ,&nbsp;Xuyong Chen ,&nbsp;Luyao Wu ,&nbsp;Ke Chen ,&nbsp;Zejian Li ,&nbsp;ChenZhao Feng ,&nbsp;Didi Zhuansun ,&nbsp;Jixin Yang ,&nbsp;Xiaojuan Wu ,&nbsp;Donghai Yu ,&nbsp;Wei Li ,&nbsp;Yonghua Niu ,&nbsp;Ying He ,&nbsp;Mingfa Wei ,&nbsp;Feng Chen ,&nbsp;Bo Xiong ,&nbsp;Jiexiong Feng ,&nbsp;Tianqi Zhu","doi":"10.1016/j.yjpso.2024.100187","DOIUrl":"10.1016/j.yjpso.2024.100187","url":null,"abstract":"","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"9 ","pages":"Article 100187"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}