Journal of EuCornea最新文献

{"title":"Descemet’s stripping automated endothelial keratoplasty: Non-attachment and detachment","authors":"Harminder S. Dua","doi":"10.1016/j.xjec.2020.03.002","DOIUrl":"10.1016/j.xjec.2020.03.002","url":null,"abstract":"","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"6 ","pages":"Pages 24-25"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.xjec.2020.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88043015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal perforation associated with the use of ketorolac tromethamine after cataract surgery","authors":"Jeniffer Jesus ,&nbsp;Inês Almeida ,&nbsp;Raquel Soares ,&nbsp;Rafael Geraldes ,&nbsp;João Chibante-Pedro","doi":"10.1016/j.xjec.2019.12.002","DOIUrl":"10.1016/j.xjec.2019.12.002","url":null,"abstract":"<div><h3>Purpose</h3><p>To report a case of corneal ulceration and perforation after<!--> <!-->cataract surgery associated with normal doses of<!--> <!-->ketorolac tromethamine (Elipa®).</p></div><div><h3>Case-Report</h3><p>An eighty-year-old man with a 15-days history of right eye (RE) cataract surgery presented to our emergency department with complaints of pain and blurred vision. He was on a treatment regimen with a combination of dexamethasone plus gentacmicin given 5 times daily and ketorolac tromethamine given 3 times daily. The patient’s visual acuity was light perception. Slit-lamp examination of the right eye revealed central corneal perforation with iris prolapse and a shrunken eye. The drug was discontinued, a bandage soft contact lens was placed and topical antibiotics and preservative-free tears were added, with a slow improvement during the following weeks. Laboratory tests, including corneal cultures, were negative or normal.</p></div><div><h3>Conclusions</h3><p>Patients treated with topical NSAIDs drugs after ocular surgery should be monitored closely. The duration of treatment and frequency of administration should be minimized, and as needed, should be discouraged. Corneal melting or perforation is a rare complication that may occur in patients receiving topical NSAIDs. Even in patients without any such history of previous ocular surface disease, severe and unexpected complications may happen.</p></div>","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"6 ","pages":"Pages 1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.xjec.2019.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79650321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Descemet’s stripping automated endothelial keratoplasty: The relationship between postoperative central corneal thickness and the requirement for re-bubbling","authors":"Morten Brok Molbech Madsen,&nbsp;Anders Ivarsen,&nbsp;Jesper Østergaard Hjortdal","doi":"10.1016/j.xjec.2019.12.006","DOIUrl":"10.1016/j.xjec.2019.12.006","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate whether central corneal thickness (CCT) at the first postoperative day was predictive of partial or complete graft detachment requiring re-bubbling.</p></div><div><h3>Methods</h3><p>We conducted a retrospective registry-based study including 943 DSAEK procedures. Included subjects were divided into 2 subgroups depending on the postoperative need for re-bubbling. Using the electronic patient record system at the Department of Ophthalmology, Aarhus University Hospital, we gathered information on CCT measured using optical pachymetry on the first postoperative day, subject characteristics as well as the need for postoperative re-bubbling. Prior to our data collection we hypothesized that increased CCT at the first postoperative examination was predictive of later re-bubbling.</p></div><div><h3>Results</h3><p>Postoperative CCT in the re-bubble group was 854 µm (CI: 836–871, N = 107) which was significantly higher than postoperative CCT of 787 µm (CI: 782; 793, N = 836) in the no-re-bubble group (P &lt; 0.001). Further, a Receiver Operating Characteristics (ROC)-curve was created. Our data revealed a sensitivity of 71.0% and specificity of 63.3% for re-bubbling using a cut-off value of 810 µm.</p></div><div><h3>Conclusion</h3><p>CCT on the first postoperative day can to some extend predict the need for postoperative re-bubbling and in this way identify eyes at risk of graft detachment requiring intervention.</p></div>","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"6 ","pages":"Pages 4-8"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.xjec.2019.12.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91471692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five years outcomes after corneal cross-linking for keratoconus","authors":"Asli Ayvaz,&nbsp;Jurriaan Brekelmans,&nbsp;Tos Berendschot,&nbsp;Mor M. Dickman,&nbsp;Nienke Visser,&nbsp;Rudy M.M.A. Nuijts,&nbsp;Isabelle E.Y. Saelens","doi":"10.1016/j.xjec.2019.12.004","DOIUrl":"10.1016/j.xjec.2019.12.004","url":null,"abstract":"","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"6 ","pages":"Pages 9-12"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.xjec.2019.12.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79003344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mucosal complications in osteo-odonto keratoprosthesis (OOKP) surgery","authors":"Venkata S. Avadhanam ,&nbsp;Alfonso Vasquez-Perez ,&nbsp;Jordan V. Chervenkoff ,&nbsp;Sarah El-Zahab ,&nbsp;Christopher Liu","doi":"10.1016/j.xjec.2020.01.001","DOIUrl":"10.1016/j.xjec.2020.01.001","url":null,"abstract":"<div><h3>Purpose</h3><p>To study the mucosal complications of osteo-odonto-keratoprosthesis (OOKP) surgery from the UK national keratoprosthesis cohort.</p></div><div><h3>Methods</h3><p>A retrospective study was conducted at the Sussex Eye Hospital, Brighton, UK. The case records of patients who underwent OOKP surgery were reviewed and analysed.</p></div><div><h3>Results</h3><p>The cohort contained 64 patients, among which 25 were females and 39 were males.</p><p>Eyelid and adnexal abnormalities were treated in 69% of the cases prior to OOKP surgery. Mucosal graft complications after OOKP affected 46% of the cases after stage 1 and 22% after stage 2. Most of the complications were observed in cases with autoimmune conditions like Stevens-Johnson syndrome (43% post-stage 1, 59% post-stage 2) and cicatrising conjunctivitis (31% post-stage 1, 20% post-stage 2). On the contrary, mucosal overgrowth covering the anterior surface of the optic, which was noted in 28% of the cases, was a common complication after stage 2. Thinning and ulceration of the mucosa was noted in 22% of cases after stage 2. Laminar exposure due to mucosal ulcers was identified in 11 cases.</p><p>The central part of the mucosa was frequently affected by thinning and ulceration after stage 1. The mucosa overlying the supero-nasal corner of the lamina was eroded commonly after stage 2 leading to exposure of the lamina. Mucosal thinning after stage 1 was treated with conservative measures such as observation and increased lubrication in 15 cases, and with surgical procedures in 7 cases. Post-stage 1 mucosal ulcers were mostly treated by surgery (7 out of 8 cases). Following stage 2, minor cases of mucosal ulcers and thinning and three cases of overgrowth were conservatively treated with lubrication and observation. However, 18 cases of overgrowth required surgical excision. All cases of lamina exposing ulcers were surgically treated. Surgical treatment of mucosal defects included mucosal grafts, flaps and eyelid corrections. Fusion of the eyelids and conversion to a trans-palpebral OOKP were performed in two cases to treat resistant mucosal ulcers. Two eyes lost lamina as a consequence of lamina exposing ulcers. One lamina was explanted due to severe resorption and one due to infection.</p></div><div><h3>Conclusion</h3><p>The majority of surgical revisions following OOKP surgery are due to mucosal problems, such as mucosal thinning and ulcerations. These may be treated with increased lubrication of the mucosa or surgical closure of the defects. Mucosal defects resulting in laminar exposure can be a serious threat to laminal viability, and must be treated promptly and aggressively.</p></div>","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"6 ","pages":"Pages 13-23"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.xjec.2020.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83218640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified crosslinking in the treatment of purulent keratitis and corneal ulcers","authors":"E. Kasparova, A. Fedorov, E. Kasparova, Biao Yang","doi":"10.1016/j.xjec.2019.12.001","DOIUrl":"https://doi.org/10.1016/j.xjec.2019.12.001","url":null,"abstract":"","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80196514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal collagen cross linking: Crossing out the microbes","authors":"Harminder S. Dua,&nbsp;Dalia G. Said","doi":"10.1016/j.xjec.2019.12.005","DOIUrl":"https://doi.org/10.1016/j.xjec.2019.12.005","url":null,"abstract":"","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"3 3","pages":"Pages 22-23"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.xjec.2019.12.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91677896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Columnar keratopathy: An early manifestation of limbal stem cell deficiency","authors":"Veronica Mas Tur, Amna Almaazmi, A. Alsaadi, M. Nubile, D. Said, L. Mastropasqua, H. Dua","doi":"10.1016/j.xjec.2019.10.001","DOIUrl":"https://doi.org/10.1016/j.xjec.2019.10.001","url":null,"abstract":"","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"250 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78844842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thygeson’s superficial punctate keratitis","authors":"T. C. Chan, H. Chau, Amar K. Bhat, K. Nischal, V. Jhanji","doi":"10.1016/j.xjec.2019.11.001","DOIUrl":"https://doi.org/10.1016/j.xjec.2019.11.001","url":null,"abstract":"","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85065578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Columnar keratopathy: An early manifestation of limbal stem cell deficiency","authors":"Veronica Mas Tur ,&nbsp;Amna AlMaazmi ,&nbsp;Ahmed AlSaadi ,&nbsp;Mario Nubile ,&nbsp;Dalia G. Said ,&nbsp;Leonardo Mastropasqua ,&nbsp;Harminder S. Dua","doi":"10.1016/j.xjec.2019.10.001","DOIUrl":"https://doi.org/10.1016/j.xjec.2019.10.001","url":null,"abstract":"<div><h3>Background/Purpose</h3><p>Stem cells of the corneal epithelium reside in the limbal palisades and associated limbal epithelial crypts. The limbus constitutes a barrier between the conjunctival and corneal phenotype of cells. When the limbal barrier is breached, stem cell deficiency (LSCD) results with conjunctivalisation of the cornea. The purpose of this study was to document an early manifestation of LSCD which is consistent and distinct across several causes of LSCD.</p></div><div><h3>Methods</h3><p>Seventeen eyes of 11 consecutive patients with diverse known causes of LSCD were included. Patients were examined clinically with the slit lamp and fluorescein staining, and by in vivo confocal microscopy. All corneas were photographed with a slit lamp camera. Seven patients underwent in vivo confocal microscopy examination.</p></div><div><h3>Results</h3><p>There were 6 males and 5 females. Six cases had bilateral involvement and the other 5 were unilateral. All patients showed predominantly superior loss of limbal anatomy with effacement of the palisades of Vogt, superficial vascularization encroaching on the peripheral cornea and alternating columns, 6–20 in number, of late fluorescein staining conjunctivalised and normal epithelium extending for a variable distance towards the corneal centre. These were related to prolonged contact lens wear, atopic keratoconjunctivitis, superficial ocular surface burns, ocular cicatricial pemphigoid, rosacea keratoconjunctivitis, old trachoma and neurotrophic keratopathy. In vivo confocal microscopy confirmed features of LSCD.</p></div><div><h3>Conclusion</h3><p>Alternating columns of conjunctivalized and normal epithelia encroaching on the cornea from the superior limbus is a distinct manifestation of early LSCD across a diverse range of causes. The reason for this manifestation is unclear but could be related to the random dysfunction or loss of the palisade architecture.</p></div>","PeriodicalId":100782,"journal":{"name":"Journal of EuCornea","volume":"3 3","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.xjec.2019.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91677895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}