Journal of Clinical Gerontology and Geriatrics最新文献

{"title":"Risk factors for cardiovascular events of antidementia drugs in Alzheimer's disease patients","authors":"Inmaculada Hernandez PharmD","doi":"10.1016/j.jcgg.2016.01.002","DOIUrl":"https://doi.org/10.1016/j.jcgg.2016.01.002","url":null,"abstract":"<div><h3>Background</h3><p>Antidementia drugs have been associated with an increased risk of cardiovascular events. The objective of this study was to identify the predictors for cardiovascular events among patients with Alzheimer's disease (AD) on antidementia drugs, mining large longitudinal claims data.</p></div><div><h3>Methods</h3><p>Using 2006–2011 claims from a 5% random sample of Medicare beneficiaries, I identified patients with AD who filled a prescription for an antidementia drug between 2007 and 2011. I followed them from the initiation of the antidementia drug until a cardiovascular event or December 31, 2011, censored by death or discontinuation of antidementia drugs. The outcome was the incidence of cardiovascular events, which include acute myocardial infarction, bradycardia, syncope, atrioventricular block, QT prolongation, and ventricular tachycardia. Covariates included predefined patient characteristics and empirical attributes identified from the claims, including <em>International Classification of Diseases, Ninth Revision</em> (ICD-9) diagnosis codes, Healthcare Common Procedure Coding System codes, and therapeutic classes of all prescriptions filled. After using feature selection to choose the top covariates, a logistic regression with multivariate variable selection was constructed.</p></div><div><h3>Results</h3><p>With an accuracy of 83.9% and a sensitivity of 93.3%, the algorithm identified 22 predictors for cardiovascular events, including a history of ischemic heart disease, congestive heart failure, syncope, stroke or transient ischemic attack, diabetes, number of other comorbidities, and procedures including venipuncture and radiologic examinations.</p></div><div><h3>Conclusion</h3><p>The results of this study can help clinicians identify AD patients with a higher risk of cardiovascular events who therefore should be prescribed antidementia drugs cautiously.</p></div>","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 3","pages":"Pages 77-82"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jcgg.2016.01.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72225791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of risk factors for falls among elderly people living in long-term care homes","authors":"Pradnya Dhargave PhD,&nbsp;Ragupathy Sendhilkumar MSc, MPT","doi":"10.1016/j.jcgg.2016.03.004","DOIUrl":"https://doi.org/10.1016/j.jcgg.2016.03.004","url":null,"abstract":"<div><h3>Background</h3><p>Falls are common among the geriatric population, causing frequent morbidity and mortality. There is an increased risk of fall among older people living in long-term care homes. Identifying risk factors for falls among older people living in old-age homes can help in the care and prevention of falls in this population.</p></div><div><h3>Aim</h3><p>To evaluate the prevalence of various risk factors for falls among older people living in long-term care homes.</p></div><div><h3>Methods</h3><p>A total of 163 elderly men and women aged 60–95 years were studied. History of falls revealed by participants, Long Term Care Fall Risk Assessment Form, Mini Mental State Examination, Berg Balance Scale, Fall Factors Assessment Form, and Dynamic Gait Index were used as the assessment tools in this study. The odds ratio for the risk factors for falls was calculated. The association between the risk of fall and the risk factors was assessed using the χ² test. The degree of functional disability between the high-risk and low-risk groups was analyzed using an independent <em>t</em> test.</p></div><div><h3>Results</h3><p>The following risk factors were significantly associated will falls: poor vision [odds ratio (OR) = 1.851], chronic conditions (OR = 1.633), vertigo (OR = 2.237), imbalance (OR = 3.105), fear of falling (OR = 3.227), and previous falls (OR = 5.661) (all <em>p</em> &lt; 0.001). There was a significant difference between high-risk and low-risk groups for all functional and cognitive measures: Long Term Care Fall Risk Assessment (<em>t</em> = 20.824), Mini Mental State Examination (<em>t</em> = −6.18), Berg Balance Scale (<em>t</em> = −12.59) and Dynamic Gait Index (<em>t</em> = −14.7) (all <em>p</em> &lt; 0.001).</p></div><div><h3>Conclusion</h3><p>We found that history of falls, poor vision, use of multiple medications, chronic diseases, use of walking aids, vertigo, and balance problems were associated with falls among the elderly population living in long-term care homes. Women had a higher risk of falls than men.</p></div>","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 3","pages":"Pages 99-103"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jcgg.2016.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72258112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daily life support for older adults evaluated by commissioned welfare volunteers","authors":"J. Onishi","doi":"10.1016/J.JCGG.2016.03.005","DOIUrl":"https://doi.org/10.1016/J.JCGG.2016.03.005","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"1 1","pages":"69-71"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79918813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurological recovery at age 92 after acute trauma and operative spinal decompression","authors":"Hazem Eltahawy, A. Ransom, G. Rajah","doi":"10.1016/J.JCGG.2015.08.001","DOIUrl":"https://doi.org/10.1016/J.JCGG.2015.08.001","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"6 1","pages":"115-117"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86620690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of giant hiatal hernia in an elderly patient: When stomach, duodenum, colon, and pancreas slide into thorax","authors":"Supakanya Wongrakpanich MD ,&nbsp;Hilit Hassidim MD ,&nbsp;Wikrom Chaiwatcharayut MD ,&nbsp;Wuttiporn Manatsathit MD","doi":"10.1016/j.jcgg.2015.06.002","DOIUrl":"https://doi.org/10.1016/j.jcgg.2015.06.002","url":null,"abstract":"<div><p>Although the incidences of hiatal hernias increase with age, respiratory symptoms caused by hiatal hernias remain extremely uncommon. We report a case of an 88-year-old female who presented with 2-months of progressive shortness of breath. Upon arrival, the patient was found to be hypoxic with oxygen saturation 90% on room air. Physical examination also showed decreased breath sounds on left basal lungs and bilateral crackles at basal lungs. Plain radiograph demonstrated an increased opacity at the left lower lobe. Subsequent computerized tomography of the chest revealed a giant hiatal hernia, containing stomach, proximal duodenum, colon, and pancreas. This case highlights the giant hiatal hernia as an unusual cause of shortness of breath, especially in elderly patients.</p></div>","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 3","pages":"Pages 112-114"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jcgg.2015.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72225788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful treatment of agitation and aggression with prazosin in an elderly patient with dementia and comorbid heart disease","authors":"M. J. Greve, D. DesJarlais, I. Ahmed","doi":"10.1016/J.JCGG.2015.06.001","DOIUrl":"https://doi.org/10.1016/J.JCGG.2015.06.001","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 1","pages":"109-111"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74336388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic profile and health condition of elderly patients attended at a community primary health center","authors":"F.H.C.V. Silva, R. Filipini, A. Guarnieri, Nathalia Vieira, Andrea Bonvini, B. Alves, L. Azzalis, V. Junqueira, F. A. Fonseca","doi":"10.1016/J.JCGG.2016.03.003","DOIUrl":"https://doi.org/10.1016/J.JCGG.2016.03.003","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"55 1","pages":"93-98"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84691679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-cultural validation of the falls efficacy scale international in elderly: Systematic literature review","authors":"C. Marques-Vieira, L. Sousa, S. Severino, L. Sousa, S. Caldeira","doi":"10.1016/J.JCGG.2015.12.002","DOIUrl":"https://doi.org/10.1016/J.JCGG.2015.12.002","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"20 1","pages":"72-76"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72962748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General Informatiom","authors":"","doi":"10.1016/S2210-8335(16)30048-X","DOIUrl":"https://doi.org/10.1016/S2210-8335(16)30048-X","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 3","pages":"Page iii"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2210-8335(16)30048-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72258109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic diseases and multimorbidity among elderly patients admitted in the medical wards of a Nigerian tertiary hospital","authors":"P. Nwani, A. Isah","doi":"10.1016/J.JCGG.2015.10.001","DOIUrl":"https://doi.org/10.1016/J.JCGG.2015.10.001","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"14 1","pages":"83-86"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79923030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}