JFO Open Ophthalmology最新文献

{"title":"Cumulative dissipated energy during phacoemulsification is associated with bleb failure in eyes with prior trabeculectomy","authors":"Amer Mosa Alwreikat ,&nbsp;Cansu Yüksel Elgin ,&nbsp;David J. Ramsey ,&nbsp;Paul R. Cotran","doi":"10.1016/j.jfop.2024.100130","DOIUrl":"10.1016/j.jfop.2024.100130","url":null,"abstract":"<div><h3>Introduction</h3><p>Trabeculectomy is the most effective method of lowering the intraocular pressure (IOP) in patients with open-angle glaucoma refractory to pharmacological treatment or laser trabeculoplasty. Many phakic glaucoma patients later require cataract surgery after trabeculectomy. The purpose of this study is to determine factors that predict bleb failure after phacoemulsification.</p></div><div><h3>Methods</h3><p>This retrospective, observational study included 33 eyes from 30 patients with open-angle glaucoma who had successful trabeculectomy with mitomycin (MMC) and subsequently underwent uncomplicated cataract surgery by means of clear corneal phacoemulsification performed by a single surgeon between 2006 and 2018. Bleb failure was defined as an eye that required the addition of two or more glaucoma medications or had an IOP &gt; 21 mmHg at any follow-up visit more than one month after surgery. Kaplan-Meier analysis was conducted to visualize bleb survival over the two-year study period.</p></div><div><h3>Results</h3><p>Ten eyes (30.3%) experienced bleb failure, at an average of 325 ± 254 days after phacoemulsification surgery. A further six eyes (18.2%) partially failed over this period. Blebs that remained fully functional (51.5%) two years after phacoemulsification surgery received lower total cumulative dissipated energy (CDE; 12.6 ± 7.2 versus 19.0 ± 7.7, <em>P</em> = 0.027).</p></div><div><h3>Conclusion</h3><p>Higher levels of ultrasound energy at the time of cataract surgery, as reflected by CDE, are associated with bleb failure. Removing cataracts at a stage when the lens is less dense so that it will require less total ultrasound energy and allow shorter duration for surgery may benefit eyes with functioning filtering blebs.</p></div>","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"8 ","pages":"Article 100130"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000540/pdfft?md5=831c5a0e9cd984631c6fd7ab44e6d983&pid=1-s2.0-S2949889924000540-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142173802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shedding light on congenital aniridia: an in-depth study of two cases","authors":"Sara Ben Addou Idrissi,&nbsp;Hassan Moutei,&nbsp;Ahmed Bennis,&nbsp;Fouad Chraibi,&nbsp;Meriem Abdellaoui,&nbsp;Idriss Benatiya Andaloussi","doi":"10.1016/j.jfop.2024.100146","DOIUrl":"10.1016/j.jfop.2024.100146","url":null,"abstract":"<div><div>Congenital aniridia is a rare ocular disorder characterized by the partial or complete absence of iris tissue. Although the classic form is associated with a range of ocular abnormalities, including foveal and optic nerve hypoplasia, nystagmus, and cataracts, it is the onset of glaucoma, cataracts, and keratopathy that most significantly impair vision in affected patients. Typically caused by mutations in the PAX6 gene, which encodes the paired box protein Pax-6, aniridia can also be associated with systemic conditions such as WAGR syndrome. This study emphasizes the importance of comprehensive ophthalmic examination and genetic testing in diagnosing and managing aniridia, particularly when associated with systemic conditions. Multidisciplinary management and regular follow-up are essential to monitor for potential complications, including Wilms' tumor, ensuring optimal care for affected patients.</div></div>","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"8 ","pages":"Article 100146"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An assessment of the vision-related quality of life among adult patients with diabetes mellitus in Accra, Ghana","authors":"Yaw Akye Essuman ,&nbsp;Benjamin Abaidoo ,&nbsp;Vera Adobea Essuman ,&nbsp;Kwesi Nyan Amissah-Arthur","doi":"10.1016/j.jfop.2024.100139","DOIUrl":"10.1016/j.jfop.2024.100139","url":null,"abstract":"<div><h3>Purpose</h3><p>To assess the overall vision-related quality of life (VRQoL) of adults with diabetes mellitus attending selected diabetic and eye care facilities in Accra, Ghana.</p></div><div><h3>Methods</h3><p>This was a hospital-based analytical cross-sectional study which took place from January to July 2023. A purposive consecutive sampling technique was used to select 150 participants. A questionnaire consisting of the WHO-PBD/VF20 and EuroQol Five Dimensional Scale instruments was used to obtain information pertaining to the demographic characteristics, vision-related quality of life and health-related quality of life of selected participants.</p></div><div><h3>Results</h3><p>The median participant age was 61.0 years. Participants with diabetic retinopathy had a worse mean overall total VRQoL score (19.4) than those without (79.9) in all domains; general visual functioning, 41.3 vs. 78.7, p = 0.002; general functioning, 15.1 vs. 80.2, p = 0.001; psychosocial, 35.7 vs. 79.3, p = 0.001; and visual symptoms, 24.4 vs. 80.4, p = 0.001. Participants with diabetic retinopathy also had a worse mean overall HRQoL score (17.4) than those without (81.0) in all domains; mobility, 32.4 vs. 79.6, p = 0.001; self-care, 53.9 vs. 77.6, p = 0.001; usual activities, 30.2 vs. 79.8, p = 0.001; pain/discomfort, 36.3 vs. 79.2, p = 0.001; and anxiety, 31.5 vs. 79.7, p = 0.001.</p></div><div><h3>Conclusion</h3><p>Our findings suggest a significant deterioration in both vision-related and health-related quality of life with the development of diabetic retinopathy. They highlight the need for nationwide screening programs to identify people with diabetes mellitus, as well as effective glycemic control to prevent the development of complications such as diabetic retinopathy.</p></div>","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"8 ","pages":"Article 100139"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000631/pdfft?md5=2dffe5984ff198286d47f9d3f0b3544f&pid=1-s2.0-S2949889924000631-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142271976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical coherence tomography (OCT) and OCT Angiography in Stages 3 and 4 proliferative sickle cell retinopathy","authors":"Ogugua Ndubuisi Okonkwo ,&nbsp;Adekunle Olubola Hassan ,&nbsp;Oyekunle Idris ,&nbsp;Arinze Anthony Onwuegbuna ,&nbsp;Toyin Akanbi ,&nbsp;Chineze Agweye ,&nbsp;Utam Ashibel","doi":"10.1016/j.jfop.2024.100144","DOIUrl":"10.1016/j.jfop.2024.100144","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate macular findings in Goldberg stages 3 and 4 proliferative sickle cell retinopathy (PSCR) using optical coherence tomography (OCT) and OCT Angiography.</div></div><div><h3>Methods</h3><div>A case-control study using retrospective OCT and OCTA data from PSCR eyes (cases) and prospective data from age and sex-matched normal (controls). OCTA data included vessel density (VD) in the superficial capillary vascular plexus (SCP) and deep capillary vascular plexus (DCP), foveal avascular zone (FAZ) characterization, including the shape (in the SCP &amp; DCP), size (area covered), and perimeter. OCT data were whole, superior, and inferior hemi-retina thickness for the superficial and deep retina.</div></div><div><h3>Results</h3><div>There were 38 OCT / OCTA scans of PSCR eyes of 21 SCD patients; ten eyes were excluded for not meeting inclusion criteria. We analyzed nineteen (19) patients (ten unilateral and 9 bilateral), 28 eyes, nine SS eyes (32%), and nineteen SC eyes (68%). The controls consisted of 29 eyes of 16 normal subjects (three unilateral and 13 bilateral). The commonest FAZ shape in PSCR was “irregular” in 14 eyes (50%), followed by “round” in 11 eyes (39.3%) versus controls, the commonest shape “round” in 18 eyes (62%), followed by “irregular” 9 eyes (31%) (p = 0.165). FAZ area and perimeter were larger in PSCR (p &gt; 0.05). The deep and superficial VD was reduced in PSCR. The mean whole deep VD for cases was 48.9 ± 6.1 versus 52.9 ± 6.4 for controls (p = 0.019). Mean whole superficial VD for cases was 47.4 ± 5.5 versus 49.8 ± 3.4 for controls (p = 0.058).</div><div>Retina thickness in the whole, superior and inferior hemi-retina, for superficial and deep retina, was higher in PSCR compared to controls (p &lt; 0.05). Superficial whole thickness for cases and controls were 287.0 μm [IQR 35.3 μm] versus 273.0 μm [IQR 18 μm] respectively (p = 0.008). Deep whole thickness for cases and controls was 287.0 μm [IQR 35.25 μm] versus 273.0 μm [IQR 18 μm] (p = 0.008).</div><div>VD was reduced in SS compared to SC eyes (deep whole VD: 50.28 ± 6.01 vs 46.78 ± 5.80) (p = 0.139). Retina thickness in SS was reduced relative to SC. Peripheral retinal laser photocoagulation did not affect VD, though it was associated with a thinner macula.</div></div><div><h3>Conclusion</h3><div>OCT/OCTA of stage 3 and 4 PSCR revealed reduced VD in the DCP and SCP. Despite the thin temporal retina in SCD, there is a thicker whole, superior, and inferior hemiretina in both the superficial and deep retina. An irregularly shaped FAZ is common, a reflection of abnormal microcapillary loss in the perifoveal area.</div></div>","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"8 ","pages":"Article 100144"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142537122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implantable Collamer Lens for Visual Rehabilitation in keratoconus - A Narrative Review of Visual and Refractive Outcomes","authors":"Rafah Fairaq ,&nbsp;Halah Bin Helayel ,&nbsp;Halla Abdulhadi ,&nbsp;Sarah M. Almuwarraee ,&nbsp;Sarah A. Almatrafi ,&nbsp;Rahaf Alruwaili ,&nbsp;Danya AlDahan ,&nbsp;Sami T. Hameed ,&nbsp;Mohammed AlShehri ,&nbsp;Mohammed AlMutlak","doi":"10.1016/j.jfop.2024.100131","DOIUrl":"10.1016/j.jfop.2024.100131","url":null,"abstract":"<div><p>Keratoconus (KC) is a progressive corneal condition characterized by ectasia, which causes progressive myopia and irregular astigmatism, resulting in decreased vision. Visual rehabilitation and refractive error management of keratoconic eyes are challenging. There is increasing interest in using the implantable collamer lens (ICL) off label in KC in light of encouraging reports of safety and efficacy in stable disease. The main concerns in considering ICL for visual rehabilitation include stability of the disease, magnitude of the refractive error, type of astigmatism, keratometric readings, and patient satisfaction with spectacles. This article reviews the indications for ICL in keratoconus and the timing between ICL implantation and corneal crosslinking and/or intrastromal corneal ring segment procedures. Additionally, we review challenges with ICL sizing in keratoconus, along with the factors and frequency associated with exchange and rotation post-ICL implantation.</p></div>","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"8 ","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000552/pdfft?md5=1e0e6a290289c64e6f5323c7feedf460&pid=1-s2.0-S2949889924000552-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142173803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concurrent squamous cell carcinoma of the conjunctiva and severe atopic dermatitis","authors":"Isana Nakajima,&nbsp;Tomoko Nakaizumi,&nbsp;Hideki Tsuji","doi":"10.1016/j.jfop.2024.100119","DOIUrl":"https://doi.org/10.1016/j.jfop.2024.100119","url":null,"abstract":"","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"7 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000436/pdfft?md5=0d4a0a26ec000a73abe83afb8c4d8660&pid=1-s2.0-S2949889924000436-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral ICE syndrome associated with secondary angle-closure glaucoma: Can it be successfully and cost-effectively managed?","authors":"Qëndresë Daka ,&nbsp;Isidora Dobratiqi,&nbsp;Naser Salihu","doi":"10.1016/j.jfop.2024.100123","DOIUrl":"https://doi.org/10.1016/j.jfop.2024.100123","url":null,"abstract":"","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"7 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000473/pdfft?md5=31f7dcfe2f94afb3c66ec7076bbf239c&pid=1-s2.0-S2949889924000473-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141583068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isotretinoin induced pre-macular hemorrhage: case report","authors":"Peyman Ghodraty,&nbsp;Farideh Mousavi,&nbsp;Amin Arasteh","doi":"10.1016/j.jfop.2024.100132","DOIUrl":"10.1016/j.jfop.2024.100132","url":null,"abstract":"","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"7 ","pages":"Article 100132"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000564/pdfft?md5=633c7f95c5b9a91a01537b09961ba205&pid=1-s2.0-S2949889924000564-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstetrical forceps induced Descemet’s membrane detachment (DMD)","authors":"Jyothi Kiran V.,&nbsp;Balamurugan Ramatchandirane","doi":"10.1016/j.jfop.2024.100129","DOIUrl":"10.1016/j.jfop.2024.100129","url":null,"abstract":"","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"7 ","pages":"Article 100129"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000539/pdfft?md5=672b1666255ad37cb7f3d764943d0a23&pid=1-s2.0-S2949889924000539-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142096570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polypoidal choroidal vasculopathy versus neovascular age related macular degeneration: a comparison of demographics, clinical presentation, and treatment outcomes in Nigerians","authors":"Ogugua Ndubuisi Okonkwo ,&nbsp;Adekunle Olubola Hassan ,&nbsp;Toyin Akanbi ,&nbsp;Chineze Agweye ,&nbsp;Arinze Anthony Onwuegbuna","doi":"10.1016/j.jfop.2024.100118","DOIUrl":"https://doi.org/10.1016/j.jfop.2024.100118","url":null,"abstract":"<div><h3>Purpose</h3><p>To compare the demographics, clinical presentation, and outcomes of intravitreal (IV) anti-VEGF monotherapy in the management of treatment-naïve polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (nAMD) in Nigerians.</p></div><div><h3>Methods</h3><p>This is a retrospective, interventional, comparative study. Data obtained from consecutively treated PCV and nAMD patients include age, sex, laterality, symptom duration, LogMAR visual acuity (pre- &amp; post-treatment), occurrence of vitreous hemorrhage, optical coherence tomography central macular thickness (CMT), and duration of clinic visits. Data was analyzed using IBM SPSS version 22.0, P &lt; 0.05.</p></div><div><h3>Results</h3><p>The sample population was 162 patients/191 eyes (nAMD 85 patients/106 eyes, and PCV 77 patients/85 eyes). The nAMD patients were older than the PCV patients (72.48 +/− 8.81 years versus 62.04 +/− 10.50 years) p = 0.000. Females constituted 45.9% of the nAMD and 57.1% of the PCV patients, p = 0.1. Symptom duration: nAMD 11 months and PCV 12 months. Bilaterality: nAMD &gt; PCV (38% versus 19%) p = 0.036. Vitreous hemorrhage: more common in PCV (42% versus 19%) p = 0.001. nAMD patients had poorer baseline vision (LogMAR 1.4 versus LogMAR 1.2) p = 0.2, thicker maculae (361 microns versus 331 microns), and received more mean intravitreal anti-VEGF injections (4 versus 3). Visual and anatomical outcomes were better for PCV; final vision (LogMAR 0.89 versus LogMAR 1.04), p = 0.064, final CMT (247 microns versus 331 microns), p = 0.05. nAMD patients had higher rate of &gt;12 months follow-up (57.6% versus 35.0%) p = 0.002.</p></div><div><h3>Conclusion</h3><p>Demographic and clinical differences exist between PCV and nAMD. Though chronic presentation for both diseases is common, treatment improves vision and anatomy in most patients, moreso in PCV. Earlier treatment will likely yield better outcomes.</p></div>","PeriodicalId":100740,"journal":{"name":"JFO Open Ophthalmology","volume":"7 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949889924000424/pdfft?md5=f3a720942c6fb6a8e9e735c22c44dc93&pid=1-s2.0-S2949889924000424-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141481492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}