{"title":"An alkaline electrolyzer having a diaphragm surface coating to enable bubble formation and thus reduce the crossover rates of the product gases","authors":"Torsten Berning , Diogo Loureiro Martinho","doi":"10.1016/j.inv.2025.100043","DOIUrl":"10.1016/j.inv.2025.100043","url":null,"abstract":"<div><div>Alkaline electrolyzer technology is widely considered the most mature and cost-effective way of producing green hydrogen, provided the electricity to operate the electrolyzer is generated via renewable energies. These electrolyzers typically consist of two electrodes, anode and cathode, separated by a diaphragm which is often Zirfon™, a porous composite separator material composed of a polysulfone matrix and ZrO in powder form. This porous membrane allows for the ion transport in the electrolyte and separates the product gases hydrogen and oxygen from each other. However, there are dissolved product gases in the liquid electrolyte that cross the porous membrane via diffusion. The main reason for this crossover rate is the fact that the aqueous liquid electrolyte phase is supersaturated with hydrogen on one side and oxygen on the other. We are proposing to add a layer of coating to the outside faces of the Zirfon membrane to promote the formation of hydrogen/oxygen bubbles outside of the membrane and thus reduce the hydrogen and oxygen crossover.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100043"},"PeriodicalIF":0.0,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carla Flores-Rodriguez , Oscar Fernando Herrera Adarme , Gustavo Mockaitis
{"title":"Revolutionizing fixed-film anaerobic bioreactors: An innovative electrostimulated system for superior biomethane and biohydrogen production","authors":"Carla Flores-Rodriguez , Oscar Fernando Herrera Adarme , Gustavo Mockaitis","doi":"10.1016/j.inv.2025.100044","DOIUrl":"10.1016/j.inv.2025.100044","url":null,"abstract":"<div><div>This invention presents an innovative anaerobic bioreactor prototype, called the electrostimulated anaerobic bioreactor (EAB), consisting of a tubular container with conductive and non-conductive supports, arranged radially and alternately around the circular cross-section and aligned with the longitudinal axis. Electrical stimulation applied to the conductive supports facilitates direct microbial electron transfer, enhancing reaction kinetics. In combination with non-conductive supports, which provide micro-niches that promote diverse microbial attachment and metabolic activity, the system fosters syntrophic interactions, accelerates substrate conversion, ensures rapid process stabilization, and maintains sustained long-term performance, thereby increasing the overall efficiency of anaerobic digestion. The EAB provides an adaptable platform for treating organic-based substrates and generating renewable energy. It enables the production of methane, hydrogen, and recoverable chemicals. It can be integrated with other bioprocesses for process optimization, testing of alternative substrates, or inclusion in biorefineries for the development of new bio-based products.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100044"},"PeriodicalIF":0.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using digital anthropometric measurements to estimate body composition","authors":"Michael V. Fedewa, Michael R. Esco","doi":"10.1016/j.inv.2025.100040","DOIUrl":"10.1016/j.inv.2025.100040","url":null,"abstract":"<div><div>Accurate measurements of body composition (Fat and Fat-Free Mass) are critically important in the clinical and sport-performance settings. In clinical settings, it is important that allied-health professionals can measure body composition to determine potential risk of obesity-related health complications, as well as to track progress during pharmacological, dietary, or physical activity programs aimed at fat loss. In sport-performance settings, athletes must measure and track improvements in Fat-Free Mass as it is related to strength and power. However, traditional body composition assessment techniques are expensive, not portable, and require a great deal of technical expertise to administer. However, recently anthropometric measurements of body size and shape have been used to estimate body composition, overcoming many of the barriers experienced with other techniques. The methods and systems described in this invention measure the anatomical dimensions of an individual from a single two-dimensional (2D) digital image. The digital image is taken from the front/anterior view using a mobile, handheld communication device. The linear measurements are used to estimate the body volume of the individual, from which total body density can be calculated from the estimated body volume and body weight. Body composition (Fat Mass and Fat-Free Mass) of the individual is derived from density using known mathematical conversion formulas.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100040"},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144722426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pseudocapacitive batteries: Methods of activating quantized capacitance energy storage mechanism","authors":"Yee Wei Foong","doi":"10.1016/j.inv.2025.100041","DOIUrl":"10.1016/j.inv.2025.100041","url":null,"abstract":"<div><div>The invention embodies a method to incorporate nanoparticles in an energy storage device, more specifically batteries and supercapacitors, to enable quantized capacitance energy storage mechanism. It operates on the principle of quantization in nanoscale, also referred to as the solvated Coulomb blockade mechanism, rather than the classical intercalation mechanism, allowing greater electron storage potential within the nanoparticles relative to classical energy storage devices. This enables pseudocapacitive battery to theoretically store as much energy as lithium-ion batteries while all its other properties resemble ultracapacitors, including the theoretical ability to have long cycle life and can be charged and discharged at very high rates, a significant departure from lithium-ion battery technology which are well known to have long charging times. This invention also enables electrochemical storage devices to be designed with sustainable materials (e.g., carbon), transitioning from the heavy reliance on precious metals (e.g., lithium, manganese, cobalt, and nickel).</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100041"},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Codony , E. Valverde , C. Galdeano , A.L. Turcu , R. Leiva , S. Vázquez
{"title":"Polycyclic compounds as soluble epoxide hydrolase inhibitors","authors":"S. Codony , E. Valverde , C. Galdeano , A.L. Turcu , R. Leiva , S. Vázquez","doi":"10.1016/j.inv.2025.100039","DOIUrl":"10.1016/j.inv.2025.100039","url":null,"abstract":"<div><div>In this invention, a novel family of benzohomoadamantane-based soluble epoxide hydrolase inhibitors is disclosed. The benzohomoadamantane scaffold is a polycyclic, readily accessible, system that features a homoadamantane unit fused with an aromatic ring. Although it has been scarcely used in medicinal chemistry, it is very versatile and permits several chemical derivatizations in its structure in order to improve the inhibitory activity and/or the DMPK properties of the compounds. This invention encompasses ureas, amides, carbamates and thioureas. The compounds are of interest for the broad range of therapeutic indications related to the inhibition of soluble epoxide hydrolase, including inflammatory diseases, pain and neurodegeneration. This invention has been licensed to a US-based start-up that is actively recruiting investors and strategic partners for advancing a selected candidate to regulatory studies.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100039"},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A transcription factor-based biosensor for identification of the polyethylene terephthalate-degrading enzyme","authors":"Shengwei Sun","doi":"10.1016/j.inv.2025.100038","DOIUrl":"10.1016/j.inv.2025.100038","url":null,"abstract":"<div><div>Screening and mining efficient polyethylene terephthalate (PET)-degrading enzyme is a promising strategy for plastic waste treatment and recycling. This invention provides a novel transcription factor-based biosensor method for identifying potential PET-degrading enzymes from the microorganisms. When PET is degraded by a specific enzyme to produce terephthalic acid (TPA), the transcription factor TphR recognizes the TPA substrate and then activates the transcription of downstream green fluorescent protein (GFP) reporter, generating measurable fluorescence signals in bacterial cells.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100038"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143182586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatty acid hydratases for hydroxy fatty acid bioproduction","authors":"Yu Chyuan Heng, Sandra Kittelmann","doi":"10.1016/j.inv.2025.100037","DOIUrl":"10.1016/j.inv.2025.100037","url":null,"abstract":"<div><div>Hydroxy fatty acids are an emerging class of compounds with growing industrial and medicinal significance, yet their chemical synthesis remains challenging. Consequently, biological synthesis has been explored as an alternative approach, with fatty acid hydratases gaining considerable interest due to their mild reaction conditions and broad substrate and product ranges. The present invention introduces 21 fatty acid hydratases with varied regio-selectivity, substrate, and product scopes, and discloses methods of producing hydroxy fatty acids from unsaturated fatty acids using individual or combinations of these enzymes. The present invention offers a foundation for industrial-scale hydroxy fatty acid bioproduction, paving the way to broaden the availability and application of hydroxy fatty acids across various sectors.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100037"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STEP carbon dioxide free production of societal staples","authors":"Stuart Licht","doi":"10.1016/j.inv.2024.100035","DOIUrl":"10.1016/j.inv.2024.100035","url":null,"abstract":"<div><div>Due to significant CO<sub>2</sub> emissions, atmospheric CO<sub>2</sub> levels have surpassed 423 ppm for the first time in recorded history, nearly doubling its level from that over the past few hundred thousand years. The primary contributor to this accumulation is anthropogenic release of CO<sub>2</sub>. Addressing the challenge of reducing atmospheric CO<sub>2</sub> requires developing carbon-neutral industrial processes to replace current CO<sub>2</sub>-intensive methods and innovating low-cost technologies for capturing and converting CO<sub>2</sub>, and exploring its potential as a feedstock for fuels and societal staples. In pursuit of these goals, efforts have focused on sustainable methods for industrial production without a high carbon footprint, for which the Solar Thermal Electrochemical Process (STEP) was developed. In STEP, solar UV–visible energy powers a photovoltaic device for high temperature electrolysis, while solar thermal energy heats another system crucial for the electrolytic processes for carbon capture and to generate societal staples, such as H<sub>2</sub> or syngas, iron, aluminum, lithium, magnesium, oxygen and chlorine at low energy and without CO<sub>2</sub>. This comprehensive use of sunlight enhances the overall efficiency of solar energy conversion compared to other methods. Applications of STEP include CO<sub>2</sub>-free synthesis of iron, bleach and fuels.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100035"},"PeriodicalIF":0.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143182585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In-situ monitoring of grease consistency","authors":"K.P. Lijesh, M.M. Khonsari","doi":"10.1016/j.inv.2024.100036","DOIUrl":"10.1016/j.inv.2024.100036","url":null,"abstract":"<div><div>The present work proposes a novel in-situ measurement technology to monitor the complex evolution of consistency during grease manufacturing. Variations in raw materials, environmental conditions, and human errors often lead to inconsistencies in the final grease consistency across production batches, causing product wastage, rework, higher costs, and production delays. To guide grease manufacturers in achieving consistent final products, a technology was developed and patented to enable real-time monitoring of rheological properties using accumulated entropy generation (AEG), a parameter derived from the principles of irreversible thermodynamics. A process sensor unit (PSU) was developed to measure AEG by recording real-time current, voltage, and process temperatures in a 5000 kg grease kettle. Tests on NLGI grade 2 and grade 1.5 grease batches demonstrated a strong linear correlation between AEG values and grease consistency, enabling a predictive model for consistency control for future batches.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100036"},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143182584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Decarbonization of iron production","authors":"Stuart Licht","doi":"10.1016/j.inv.2024.100033","DOIUrl":"10.1016/j.inv.2024.100033","url":null,"abstract":"<div><div>Today's carbothermal process for producing iron from iron ore has a high carbon footprint causing massive CO<sub>2</sub> emissions into the atmosphere. Alternatives are needed to mitigate the climate change effects of rising CO<sub>2</sub> concentrations. This invention is a low carbon footprint, zero CO<sub>2</sub> emission, alternative iron production process. Iron oxide ore is discovered to be highly soluble in certain molten carbonates, such as lithium carbonate. Iron is produced electrolytically in these molten salts at approximately 750°C by splitting iron oxide into iron metal and oxygen. This is a high efficiency, low energy, low-carbon footprint alternative to the massive CO<sub>2</sub> emissions associated with the conventional iron industry.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"4 ","pages":"Article 100033"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142532755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}