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Using digital anthropometric measurements to estimate body composition 使用数字人体测量来估计身体成分
Invention Disclosure Pub Date : 2025-07-18 DOI: 10.1016/j.inv.2025.100040
Michael V. Fedewa, Michael R. Esco
{"title":"Using digital anthropometric measurements to estimate body composition","authors":"Michael V. Fedewa,&nbsp;Michael R. Esco","doi":"10.1016/j.inv.2025.100040","DOIUrl":"10.1016/j.inv.2025.100040","url":null,"abstract":"<div><div>Accurate measurements of body composition (Fat and Fat-Free Mass) are critically important in the clinical and sport-performance settings. In clinical settings, it is important that allied-health professionals can measure body composition to determine potential risk of obesity-related health complications, as well as to track progress during pharmacological, dietary, or physical activity programs aimed at fat loss. In sport-performance settings, athletes must measure and track improvements in Fat-Free Mass as it is related to strength and power. However, traditional body composition assessment techniques are expensive, not portable, and require a great deal of technical expertise to administer. However, recently anthropometric measurements of body size and shape have been used to estimate body composition, overcoming many of the barriers experienced with other techniques. The methods and systems described in this invention measure the anatomical dimensions of an individual from a single two-dimensional (2D) digital image. The digital image is taken from the front/anterior view using a mobile, handheld communication device. The linear measurements are used to estimate the body volume of the individual, from which total body density can be calculated from the estimated body volume and body weight. Body composition (Fat Mass and Fat-Free Mass) of the individual is derived from density using known mathematical conversion formulas.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100040"},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144722426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudocapacitive batteries: Methods of activating quantized capacitance energy storage mechanism 伪电容电池:激活量子化电容储能机制的方法
Invention Disclosure Pub Date : 2025-07-17 DOI: 10.1016/j.inv.2025.100041
Yee Wei Foong
{"title":"Pseudocapacitive batteries: Methods of activating quantized capacitance energy storage mechanism","authors":"Yee Wei Foong","doi":"10.1016/j.inv.2025.100041","DOIUrl":"10.1016/j.inv.2025.100041","url":null,"abstract":"<div><div>The invention embodies a method to incorporate nanoparticles in an energy storage device, more specifically batteries and supercapacitors, to enable quantized capacitance energy storage mechanism. It operates on the principle of quantization in nanoscale, also referred to as the solvated Coulomb blockade mechanism, rather than the classical intercalation mechanism, allowing greater electron storage potential within the nanoparticles relative to classical energy storage devices. This enables pseudocapacitive battery to theoretically store as much energy as lithium-ion batteries while all its other properties resemble ultracapacitors, including the theoretical ability to have long cycle life and can be charged and discharged at very high rates, a significant departure from lithium-ion battery technology which are well known to have long charging times. This invention also enables electrochemical storage devices to be designed with sustainable materials (e.g., carbon), transitioning from the heavy reliance on precious metals (e.g., lithium, manganese, cobalt, and nickel).</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100041"},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polycyclic compounds as soluble epoxide hydrolase inhibitors 多环化合物作为可溶性环氧化物水解酶抑制剂
Invention Disclosure Pub Date : 2025-03-15 DOI: 10.1016/j.inv.2025.100039
S. Codony , E. Valverde , C. Galdeano , A.L. Turcu , R. Leiva , S. Vázquez
{"title":"Polycyclic compounds as soluble epoxide hydrolase inhibitors","authors":"S. Codony ,&nbsp;E. Valverde ,&nbsp;C. Galdeano ,&nbsp;A.L. Turcu ,&nbsp;R. Leiva ,&nbsp;S. Vázquez","doi":"10.1016/j.inv.2025.100039","DOIUrl":"10.1016/j.inv.2025.100039","url":null,"abstract":"<div><div>In this invention, a novel family of benzohomoadamantane-based soluble epoxide hydrolase inhibitors is disclosed. The benzohomoadamantane scaffold is a polycyclic, readily accessible, system that features a homoadamantane unit fused with an aromatic ring. Although it has been scarcely used in medicinal chemistry, it is very versatile and permits several chemical derivatizations in its structure in order to improve the inhibitory activity and/or the DMPK properties of the compounds. This invention encompasses ureas, amides, carbamates and thioureas. The compounds are of interest for the broad range of therapeutic indications related to the inhibition of soluble epoxide hydrolase, including inflammatory diseases, pain and neurodegeneration. This invention has been licensed to a US-based start-up that is actively recruiting investors and strategic partners for advancing a selected candidate to regulatory studies.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100039"},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A transcription factor-based biosensor for identification of the polyethylene terephthalate-degrading enzyme 一种基于转录因子的生物传感器,用于鉴定聚对苯二甲酸乙二醇酯降解酶
Invention Disclosure Pub Date : 2025-02-01 DOI: 10.1016/j.inv.2025.100038
Shengwei Sun
{"title":"A transcription factor-based biosensor for identification of the polyethylene terephthalate-degrading enzyme","authors":"Shengwei Sun","doi":"10.1016/j.inv.2025.100038","DOIUrl":"10.1016/j.inv.2025.100038","url":null,"abstract":"<div><div>Screening and mining efficient polyethylene terephthalate (PET)-degrading enzyme is a promising strategy for plastic waste treatment and recycling. This invention provides a novel transcription factor-based biosensor method for identifying potential PET-degrading enzymes from the microorganisms. When PET is degraded by a specific enzyme to produce terephthalic acid (TPA), the transcription factor TphR recognizes the TPA substrate and then activates the transcription of downstream green fluorescent protein (GFP) reporter, generating measurable fluorescence signals in bacterial cells.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100038"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143182586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatty acid hydratases for hydroxy fatty acid bioproduction 用于羟基脂肪酸生物生产的脂肪酸水合酶
Invention Disclosure Pub Date : 2025-02-01 DOI: 10.1016/j.inv.2025.100037
Yu Chyuan Heng, Sandra Kittelmann
{"title":"Fatty acid hydratases for hydroxy fatty acid bioproduction","authors":"Yu Chyuan Heng,&nbsp;Sandra Kittelmann","doi":"10.1016/j.inv.2025.100037","DOIUrl":"10.1016/j.inv.2025.100037","url":null,"abstract":"<div><div>Hydroxy fatty acids are an emerging class of compounds with growing industrial and medicinal significance, yet their chemical synthesis remains challenging. Consequently, biological synthesis has been explored as an alternative approach, with fatty acid hydratases gaining considerable interest due to their mild reaction conditions and broad substrate and product ranges. The present invention introduces 21 fatty acid hydratases with varied regio-selectivity, substrate, and product scopes, and discloses methods of producing hydroxy fatty acids from unsaturated fatty acids using individual or combinations of these enzymes. The present invention offers a foundation for industrial-scale hydroxy fatty acid bioproduction, paving the way to broaden the availability and application of hydroxy fatty acids across various sectors.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100037"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STEP carbon dioxide free production of societal staples 以不产生二氧化碳的 STEP 方式生产社会主食
Invention Disclosure Pub Date : 2024-12-25 DOI: 10.1016/j.inv.2024.100035
Stuart Licht
{"title":"STEP carbon dioxide free production of societal staples","authors":"Stuart Licht","doi":"10.1016/j.inv.2024.100035","DOIUrl":"10.1016/j.inv.2024.100035","url":null,"abstract":"<div><div>Due to significant CO<sub>2</sub> emissions, atmospheric CO<sub>2</sub> levels have surpassed 423 ppm for the first time in recorded history, nearly doubling its level from that over the past few hundred thousand years. The primary contributor to this accumulation is anthropogenic release of CO<sub>2</sub>. Addressing the challenge of reducing atmospheric CO<sub>2</sub> requires developing carbon-neutral industrial processes to replace current CO<sub>2</sub>-intensive methods and innovating low-cost technologies for capturing and converting CO<sub>2</sub>, and exploring its potential as a feedstock for fuels and societal staples. In pursuit of these goals, efforts have focused on sustainable methods for industrial production without a high carbon footprint, for which the Solar Thermal Electrochemical Process (STEP) was developed. In STEP, solar UV–visible energy powers a photovoltaic device for high temperature electrolysis, while solar thermal energy heats another system crucial for the electrolytic processes for carbon capture and to generate societal staples, such as H<sub>2</sub> or syngas, iron, aluminum, lithium, magnesium, oxygen and chlorine at low energy and without CO<sub>2</sub>. This comprehensive use of sunlight enhances the overall efficiency of solar energy conversion compared to other methods. Applications of STEP include CO<sub>2</sub>-free synthesis of iron, bleach and fuels.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100035"},"PeriodicalIF":0.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143182585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-situ monitoring of grease consistency 润滑脂浓度的现场监测
Invention Disclosure Pub Date : 2024-12-24 DOI: 10.1016/j.inv.2024.100036
K.P. Lijesh, M.M. Khonsari
{"title":"In-situ monitoring of grease consistency","authors":"K.P. Lijesh,&nbsp;M.M. Khonsari","doi":"10.1016/j.inv.2024.100036","DOIUrl":"10.1016/j.inv.2024.100036","url":null,"abstract":"<div><div>The present work proposes a novel in-situ measurement technology to monitor the complex evolution of consistency during grease manufacturing. Variations in raw materials, environmental conditions, and human errors often lead to inconsistencies in the final grease consistency across production batches, causing product wastage, rework, higher costs, and production delays. To guide grease manufacturers in achieving consistent final products, a technology was developed and patented to enable real-time monitoring of rheological properties using accumulated entropy generation (AEG), a parameter derived from the principles of irreversible thermodynamics. A process sensor unit (PSU) was developed to measure AEG by recording real-time current, voltage, and process temperatures in a 5000 kg grease kettle. Tests on NLGI grade 2 and grade 1.5 grease batches demonstrated a strong linear correlation between AEG values and grease consistency, enabling a predictive model for consistency control for future batches.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"5 ","pages":"Article 100036"},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143182584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decarbonization of iron production 铁生产的去碳化
Invention Disclosure Pub Date : 2024-01-01 DOI: 10.1016/j.inv.2024.100033
Stuart Licht
{"title":"Decarbonization of iron production","authors":"Stuart Licht","doi":"10.1016/j.inv.2024.100033","DOIUrl":"10.1016/j.inv.2024.100033","url":null,"abstract":"<div><div>Today's carbothermal process for producing iron from iron ore has a high carbon footprint causing massive CO<sub>2</sub> emissions into the atmosphere. Alternatives are needed to mitigate the climate change effects of rising CO<sub>2</sub> concentrations. This invention is a low carbon footprint, zero CO<sub>2</sub> emission, alternative iron production process. Iron oxide ore is discovered to be highly soluble in certain molten carbonates, such as lithium carbonate. Iron is produced electrolytically in these molten salts at approximately 750°C by splitting iron oxide into iron metal and oxygen. This is a high efficiency, low energy, low-carbon footprint alternative to the massive CO<sub>2</sub> emissions associated with the conventional iron industry.</div></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"4 ","pages":"Article 100033"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142532755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular building blocks and nutrients as a novel cancer treatment 作为新型癌症治疗方法的分子构件和营养素
Invention Disclosure Pub Date : 2024-01-01 DOI: 10.1016/j.inv.2024.100021
Thomas Manning , Teighlor Livingston , Capri Persaud , Akshil Patel , James Nienow
{"title":"Molecular building blocks and nutrients as a novel cancer treatment","authors":"Thomas Manning ,&nbsp;Teighlor Livingston ,&nbsp;Capri Persaud ,&nbsp;Akshil Patel ,&nbsp;James Nienow","doi":"10.1016/j.inv.2024.100021","DOIUrl":"10.1016/j.inv.2024.100021","url":null,"abstract":"<div><p>In this invention, a novel cancer drug is formed by Cu(II) and Fe(III) binding the medicinal molecule Paclitaxel (PAC). This complexation increases the water solubility of the taxane, alters the structure so resistance mechanisms do not recognize it, and adds additional toxicity. The copper (II) species can generate reactive oxidation species (ROS) and randomly bind and distort proteins within a cancer cell. Cu(II) also plays a role in accelerating angiogenesis and creates a Trojan horse effect that increases its uptake rate by the cancer cells. The empirical formula for the complex is Cu<sub>x</sub>Fe<sub>y</sub>PAC<sub>1</sub>, where <em>X</em> + <em>Y</em> equals a value between 0 and 10.</p></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"4 ","pages":"Article 100021"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772444124000028/pdfft?md5=04c0bb46cb8c9ac88125a69ad17e6775&pid=1-s2.0-S2772444124000028-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140268610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel solid catalyst sulfonic acid functionalized carbonaceous material for biodiesel production 用于生物柴油生产的新型固体催化剂磺酸功能化碳质材料
Invention Disclosure Pub Date : 2024-01-01 DOI: 10.1016/j.inv.2024.100020
Joseph VL Ruatpuia, Samuel Lalthazuala Rokhum
{"title":"Novel solid catalyst sulfonic acid functionalized carbonaceous material for biodiesel production","authors":"Joseph VL Ruatpuia,&nbsp;Samuel Lalthazuala Rokhum","doi":"10.1016/j.inv.2024.100020","DOIUrl":"https://doi.org/10.1016/j.inv.2024.100020","url":null,"abstract":"<div><p>A one-pot hydrothermal carbonization-sulfonation procedure was employed to develop robust, carbon-based solid catalyst sulfonic acid functionalized carbonaceous material (SAFACAM) possessing acidic functions up to 5.31 mmol g<sup>−1</sup> for the first time at 80 °C. With its atom-efficient, one-pot preparation from a plentiful natural biomass derivative (glucose), the current catalyst benefits the environment and has the potential to lower the overall cost of producing biodiesel by converting cheap raw materials. The diminishing supply of fossil fuels coupled with the polluting effects of their use is driving the quest for more sustainable sources of energy. The pursuit of producing biodiesel from affordable, non-edible oil has become progressively significant due to its dual benefits of sustainability and cost-efficiency. In this context, <em>Jatropha curcas</em> oil (JCO) has gained attention in the energy sector, as it holds promise as a viable feedstock for biodiesel manufacturing and a renewable energy solution for numerous nations. Additionally, the catalyst exhibited exceptional physical stability and reactivity throughout 5 consecutive cycles, establishing its potential as a highly promising catalyst for sustainable biodiesel manufacture.</p></div>","PeriodicalId":100728,"journal":{"name":"Invention Disclosure","volume":"4 ","pages":"Article 100020"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772444124000016/pdfft?md5=81c5989e602f24450b829369714be0be&pid=1-s2.0-S2772444124000016-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139675935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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