International Journal of Medical Microbiology Supplements最新文献

{"title":"Safety and immunogenicity of FSME-IMMUN® “new” vs. Encepur® in adults","authors":"","doi":"10.1016/S1433-1128(04)80022-6","DOIUrl":"https://doi.org/10.1016/S1433-1128(04)80022-6","url":null,"abstract":"","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Pages 128-129"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80022-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138272983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographical and seasonal variation in detecting Borrelia burgdorferi sensu lato in rodents of North East Austria","authors":"","doi":"10.1016/S1433-1128(04)80019-6","DOIUrl":"https://doi.org/10.1016/S1433-1128(04)80019-6","url":null,"abstract":"","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Page 119"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80019-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138273456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Message of greetings","authors":"Dr. Carola Reimann (Member of the Deutscher Bundestag)","doi":"10.1016/S1433-1128(04)80002-0","DOIUrl":"10.1016/S1433-1128(04)80002-0","url":null,"abstract":"","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Page 3"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80002-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75485453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TBE booster immunization in adults — first experience with a new tick-borne encephalitis (TBE) vaccine, free of protein-derived stabilizer","authors":"Olaf Zent ,&nbsp;Tino F. Schwarz ,&nbsp;Annelie Plentz ,&nbsp;Angelika Banzhoff ,&nbsp;Wolfgang Jilg","doi":"10.1016/S1433-1128(04)80024-X","DOIUrl":"10.1016/S1433-1128(04)80024-X","url":null,"abstract":"<div><p>A total of 222 adult subjects, all of whom received primary immunization according to the rapid immunization schedule in a preceding clinical trial with either a new (i.e. polygeline free) or formerly licensed (i.e. polygeline containing) TBE vaccine were invited for extension studies. The subjects received the first booster immunization with the new TBE vaccine at 12 to 18 months after primary immunization. Subsequently, a total of 191 of the 222 subjects could be enrolled in a serological follow-up one year after the booster immunization. Neutralizing TBE antibody titers were determined prior to, 21 days after and approximately 12 months after booster immunization. Prior to first booster immunization, TBE antibodies (GMTs) had remained on a high level and were far above the detection limit of the neutralization test used. All subjects of the per protocol population who were primarily immunized with the new TBE vaccine formulation and all but one subject of the control group were still seropositive prior to the booster. All subjects showed a sharp increase of TBE antibodies following the booster immunization. Within the 12 months follow-up period, neutralizing TBE antibody titers remained on a high level. The booster vaccination was well tolerated by the subjects. Only very few febrile reactions (&lt;1%) none higher than 38.5°C were reported. No serious or unexpected adverse events related to vaccination were reported. These successful results in terms of both immunogenicity and safety indicate that TBE vaccination with this new TBE vaccine can be used safely in adults. A long lasting immunity can be concluded from the strong immune response following the booster immunization.</p></div>","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Pages 134-138"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80024-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24522106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decreasing tick-borne disease risk in the US by intervening in the natural cycle: lessons from the woods thus far","authors":"","doi":"10.1016/S1433-1128(04)80026-3","DOIUrl":"https://doi.org/10.1016/S1433-1128(04)80026-3","url":null,"abstract":"","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Page 145"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80026-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138272981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodiversity in canine babesiae: molecular and epidemiological investigations","authors":"","doi":"10.1016/S1433-1128(04)80017-2","DOIUrl":"https://doi.org/10.1016/S1433-1128(04)80017-2","url":null,"abstract":"","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Page 117"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80017-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138273457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reservoir host identification by analysis of host-seeking ticks","authors":"","doi":"10.1016/S1433-1128(04)80018-4","DOIUrl":"https://doi.org/10.1016/S1433-1128(04)80018-4","url":null,"abstract":"","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Page 118"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80018-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138273458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Message of greetings","authors":"Dr. Manfred Lückemeyer (Acting Director of the German Federal Institute for Risk Assessment)","doi":"10.1016/S1433-1128(04)80001-9","DOIUrl":"10.1016/S1433-1128(04)80001-9","url":null,"abstract":"","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Page 2"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80001-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76947547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Test systems for tick repellents","authors":"Hans Dautel","doi":"10.1016/S1433-1128(04)80037-8","DOIUrl":"10.1016/S1433-1128(04)80037-8","url":null,"abstract":"<div><p>There is an interest in the development of repellents for personal protection of humans and animals against ticks. Evaluation of new substances or formulations needs adequate test procedures to show efficacy of the compounds. A variety of repellent assays for ticks are described in the literature. Available biotests can be grouped in three categories (i) use of live hosts, (ii) use of some kind of tick attractant associated with hosts, or (iii) no use of attractants at all. The latter are often better to standardize and are cheap, but suffer from a poor ability to filter out weak repellents. The former two are usually more predictive in terms of forecasting the efficacy of the product under practical conditions, although sometimes difficult to standardize, particularly in the field, but usually expensive and time consuming. Therefore, recent developments concentrated on laboratory assays like the Moving-object bioassay or the human volunteer test, allowing the tick to display its host-seeking behaviour as close as possible to that shown in nature, yet offering a standardized procedure.</p></div>","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Pages 182-188"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80037-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24521440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A tick-borne encephalitis ceiling in Central Europe has moved upwards during the last 30 years: Possible impact of global warming?","authors":"Petr Zeman ,&nbsp;Cestmir Beneš","doi":"10.1016/S1433-1128(04)80008-1","DOIUrl":"10.1016/S1433-1128(04)80008-1","url":null,"abstract":"<div><p>The geographic/temporal pattern of cases of tick-borne encephalitis (TBE) registered in the Czech Republic since 1970 was analysed to verify the surmise of a global warming effect. Using a geographic information system, over 8,700 notified places of infection were pinpointed on a map and overlaid with a digital elevation model to estimate the vertical distribution of the cases. Series of yearly disease ceilings (assessed alternatively as the respective maximum altitude or mean altitudes of the upper 5 or 10 cases) were tested against the null hypothesis of random elevation course and analysed for correlation with concomitant factors (yearly TBE incidence rate, mean yearly temperature, population density of small rodents and roe deer). Statistical tests proved that the TBE ceiling has gradually moved upwards in the course of the last three decades. The average rate of ascension within this period was approx. 5.4 ± 1.7 m yearly, which corresponds well with concurrent mean temperature rising of approx. 0.036 ± 0.007°C yearly, and the vertical temperature gradient of 0.0065 ± 0.0004°C m⁻¹. The TBE-ceiling estimates significantly correlated with TBE-incidence data and the mean yearly temperature recorded 1–2 years earlier. Although TBE incidence correlated with rodent population density that was observed 1–2 years earlier, the TBE ceiling does not seem to be influenced by rodent population dynamics nor did the population dynamics correlate with mean yearly temperatures. TBE incidence as well as mean altitudes of the upper 10 cases also correlated with official data on harvested roe deer. Overall, the fluctuations of TBE incidence and TBE ceiling proved to be synchronous processes that correspond with temperature changes. Although the dependence of TBE on temperature is not a direct one and various factors could be involved, an impact of climate warming on the vertical disease distribution in Central Europe is evident.</p></div>","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Pages 48-54"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80008-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24522226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}