Infectious Medicine最新文献

{"title":"Isolation and characterization of a novel coltivirus from Haemaphysalis concinna ticks in Northeastern China","authors":"Yu-Hong Yang ,&nbsp;Ji-Xu Li ,&nbsp;Rui-Chen Wang ,&nbsp;Qi-Kai Yin ,&nbsp;Shi-Hong Fu ,&nbsp;Kai Nie ,&nbsp;Qian-Qian Cui ,&nbsp;Song-Tao Xu ,&nbsp;Qiang Wei ,&nbsp;Fan Li ,&nbsp;Xing-Zhou Li ,&nbsp;Huan-Yu Wang","doi":"10.1016/j.imj.2025.100179","DOIUrl":"10.1016/j.imj.2025.100179","url":null,"abstract":"<div><h3>Backgroud</h3><div>Coltiviruses are spherical, non-enveloped viruses with 12 double-stranded RNA segments, belonging to the family <em>Spinareoviridae</em>, and predominantly transmitted by ticks. This study isolated and characterized a novel coltivirus, designated Woodland tick reovirus (WLTRV), from <em>Haemaphysalis concinna</em> ticks collected in Helong City, Jilin Province, in Northeastern China.</div></div><div><h3>Methods</h3><div>SW-13 and Vero cells were used to isolate WLTRV through three blind passages, while seven mammalian cell lines assessed viral growth. Viral morphology was observed by electron microscopy. Next-generation sequencing, 5ʹ and 3ʹ rapid amplification of cDNA ends were used to determine WLTRV whole genome sequences, and phylogenetic methods were used to characterize WLTRV. A real-time quantitative polymerase chain reaction (RT-qPCR) was used to detect WLTRV RNA in ticks.</div></div><div><h3>Results</h3><div>WLTRV grew and exerted cytopathic effects in human (SW-13 and 293T) and mouse (BHK-21 and N2A) cell lines, revealing its potential to infect mammals. Phylogenetic analysis based on RNA-dependent RNA polymerase sequences classified WLTRV within the genus <em>Coltivirus</em>, with a close evolutionary relationship to Tarumizu tick virus. The nucleotide and amino acid sequence homologies between WLTRV and Tarumizu tick virus across the 12 segments analyzed ranged from approximately 44.79% to 69.09% and 33.73% to 75.60%, respectively. WLTRV shared conserved the 5ʹ-terminal (GACA^A/_U^U/_A) and 3ʹ-terminal (UGCAGUC) consensus sequences of the genus <em>Coltivirus</em> genomes. Electron microscopy revealed WLTRV as spherical (diameter ∼80 nm), non-enveloped, and morphologically consistent with coltiviruses. Among the 4,717 ticks collected from six towns in the Yanbian Korean Autonomous Prefecture, WLTRV RNA was only detected in <em>H. concinna</em> (0.95% virus-carrying rate) but not in <em>Haemaphysalis japonica, Haemaphysalis longicornis, Ixodes persulcatus</em>, and <em>Dermacentor silvarum</em>.</div></div><div><h3>Conclusions</h3><div>This study represents the first isolation and identification of WLTRV from <em>H. concinna</em> in the Yanbian Korean Autonomous Prefecture, providing new insights into the genetic diversity and evolution of the genus <em>Coltivirus</em>.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 2","pages":"Article 100179"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid and sensitive detection of human adenovirus types 3 and 7 using CRISPR-Cas12b coupled with multiple cross displacement amplification","authors":"Xinbei Jia ,&nbsp;Linglong Wan ,&nbsp;Fei Xiao ,&nbsp;Xiaolan Huang ,&nbsp;Juan Zhou ,&nbsp;Yi Wang ,&nbsp;Jun Tai","doi":"10.1016/j.imj.2025.100181","DOIUrl":"10.1016/j.imj.2025.100181","url":null,"abstract":"<div><h3>Background</h3><div>Human adenovirus type 3 (HAdV-3) and 7 (HAdV-7) are significant causative agents of acute respiratory tract infections that are prevalent among school-based outbreaks across China. Rapid and accurate diagnosis is crucial for effective control and treatment of HAdV infection.</div></div><div><h3>Methods</h3><div>Here, we developed a novel diagnostic assay combining multiple cross displacement amplification (MCDA) with CRISPR-Cas12b technology, designated HAdV-MCDA-CRISPR, to rapidly detect HAdV-3 and HAdV-7. The assay targets a highly conserved region of the hexon gene, enabling broad detection of these serotypes. The protocol includes DNA extraction (15 minutes), MCDA amplification (40 minutes), and CRISPR detection (5 minutes), and is completed within one hour. Specificity was validated by testing against non-HAdV pathogens, while sensitivity was assessed using serial dilutions of hexon-containing plasmid DNA. Clinical performance was evaluated using 88 patient samples.</div></div><div><h3>Results</h3><div>The HAdV-MCDA-CRISPR assay demonstrated high sensitivity, detecting as little as 5 fg HAdV plasmid DNA per reaction, and showed no cross-reactivity with other common respiratory pathogens. Clinical validation using 88 patient samples further demonstrated the diagnostic accuracy of HAdV-MCDA-CRISPR.</div></div><div><h3>Conclusions</h3><div>HAdV-MCDA-CRISPR is a rapid, sensitive, and specific tool for diagnosing HAdV-3 and HAdV-7 infections, offering potential for timely clinical intervention and enhanced epidemiological surveillance.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 2","pages":"Article 100181"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143948125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Culture-negative liver abscess identified with plasma microbial cell-free DNA sequencing: A case report","authors":"Yuanchao Xue,&nbsp;Filipe M. Cerqueira,&nbsp;Heather L. Stevenson,&nbsp;Natalie Williams-Bouyer,&nbsp;Rong Fang","doi":"10.1016/j.imj.2025.100180","DOIUrl":"10.1016/j.imj.2025.100180","url":null,"abstract":"<div><div>Pyogenic liver abscess (PLA) is a potentially life-threatening disease. Early diagnosis and appropriate treatment are crucial to ensure high-quality healthcare for patients with PLA. However, this is complicated by their non-specific clinical symptoms. In addition, the etiologic organisms responsible for PLA are frequently culture-negative, thus complicating clinical decision-making. Here, we report a case of PLA caused by <em>Streptococcus intermedius,</em> as identified via DNA metagenomic sequencing of plasma.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 2","pages":"Article 100180"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144107660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative exploration of Hep-2 cell culture in the isolation and culture of Mycoplasma pneumoniae","authors":"Weiwei Wu ,&nbsp;Wenwen Zhu ,&nbsp;Jing Tong ,&nbsp;Qiang Zhou ,&nbsp;Yanping Xu ,&nbsp;Xiuxiu Zhou ,&nbsp;Yu Du ,&nbsp;Jun Bi ,&nbsp;Liguo Zhu","doi":"10.1016/j.imj.2025.100178","DOIUrl":"10.1016/j.imj.2025.100178","url":null,"abstract":"<div><h3>Background</h3><div>The isolation and culture of <em>Mycoplasma pneumoniae</em> (MP) is time-consuming and has a low success rate. On the basis of the fact that cell lines are susceptible to MP contamination, we explored the possibility of using Hep-2 cell culture for the isolation and culture of MP, to overcome this long-standing technical problem.</div></div><div><h3>Methods</h3><div>Quantitative Real-time PCR (qPCR) was used to detect MP in the nucleic acid samples of clinically suspected mycoplasma-infected patients. Positive samples were cultured in Hep-2 cells, with the classical commercial MP liquid culture medium serving as a control. For successful isolation of MP, the broth culture medium was used for subculture, then transferred to solid agar medium for isolation. The isolated strains were identified by nucleic acid and whole-genome sequencing.</div></div><div><h3>Results</h3><div>Among the 20 throat swab samples collected from individuals with influenza-like illness, 10 MP-positive samples were detected by qPCR. Five strains of <em>Mycoplasma</em> were successfully cultured in Hep-2 cells within 7–10 days, while one strain was cultured in commercial MP broth after 21 days, with isolation rates of 50% and 10%, respectively. After repeated subculturing in liquid medium and inoculation onto solid medium, “fried-egg”-like colonies emerged. The isolated strains were identified by nucleic acid and whole-genome sequencing.</div></div><div><h3>Conclusions</h3><div>The use of cell culture enables the rapid and effective isolation and culture of MP, addressing the long-standing challenge of MP cultivation. This advancement may contribute to improved antibiotic development, vaccine research, and the maintenance of global public health security.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 2","pages":"Article 100178"},"PeriodicalIF":0.0,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mysterious Oropouche virus: Transmission, symptoms, and control","authors":"Sejal Porwal ,&nbsp;Rishabha Malviya ,&nbsp;Sathvik Belagodu Sridhar ,&nbsp;Javedh Shareef ,&nbsp;Tarun Wadhwa","doi":"10.1016/j.imj.2025.100177","DOIUrl":"10.1016/j.imj.2025.100177","url":null,"abstract":"<div><div>The Oropouche virus (OROV) is a new zoonotic arbovirus that mostly affects Brazil and nearby countries. Since its discovery in 1955, it has caused more than 500,000 infections, with symptoms ranging from fever and headache to serious neuroinvasive disorders such as meningitis and encephalitis. The virus spreads through urban and sylvatic cycles via vectors such as <em>Culicoides</em> midges and <em>Culex</em> mosquitos, with humans and some vertebrates serving as amplifying hosts. The manuscript aims to analyze the transmission dynamics, clinical manifestations, diagnostic approaches, and potential preventive strategies for OROV. OROV is becoming an increasing health concern due to its global expansion and potential for serious consequences. Its growing threat, especially in light of the possibility of congenital abnormalities, is highlighted by the first recorded deaths in 2024 and the verification of vertical transmission. Clinical symptoms overlap greatly with other arboviruses, limiting early diagnosis; nonetheless, molecular approaches such as RT-PCR are crucial for identification. The current therapy is restricted to symptom control, highlighting the critical need for effective vaccinations. Live attenuated vaccination candidates and innovative techniques based on reverse genetics systems are both promising discoveries. However, the genetic variety of OROV strains poses obstacles to obtaining broad protection. To combat OROV, improved surveillance, strong public health initiatives, and quick vaccine development are needed. Public education and sustainable vector control are also essential for controlling outbreaks and lessening the virus effects.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 2","pages":"Article 100177"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phage treatment of multidrug-resistant bacterial infections in humans, animals, and plants: The current status and future prospects","authors":"Omor Faruk ,&nbsp;Zilhas Ahmed Jewel ,&nbsp;Sanjoy Bairagi ,&nbsp;Mohammad Rasheduzzaman ,&nbsp;Hindol Bagchi ,&nbsp;Akber Subahan Mahbub Tuha ,&nbsp;Imran Hossain ,&nbsp;Ayon Bala ,&nbsp;Sarafat Ali","doi":"10.1016/j.imj.2025.100168","DOIUrl":"10.1016/j.imj.2025.100168","url":null,"abstract":"<div><div>Phages, including the viruses that lyse bacterial pathogens, offer unique therapeutic advantages, including their capacity to lyse antibiotic-resistant bacteria and disrupt biofilms without harming the host microbiota. The lack of new effective antibiotics and the growing limitations of existing antibiotics have refocused attention on phage therapy as an option in complex clinical cases such as burn wounds, cystic fibrosis, and pneumonia. This review describes clinical cases and preclinical studies in which phage therapy has been effective in both human and veterinary medicine, and in an agricultural context. In addition, critical challenges, such as the narrow host range of bacteriophages, the possibility of bacterial resistance, and regulatory constraints on the widespread use of phage therapy, are addressed. Future directions include optimizing phage therapy through strategies ranging from phage cocktails to broadening phage host range through genetic modification, and using phages as vaccines or biocontrol agents. In the future, if phage can be efficiently delivered, maintained in a stable state, and phage–antibiotic synergy can be achieved, phage therapy will offer much needed treatment options. However, the successful implementation of phage therapy within the current standards of practice will also require the considerable development of regulatory infrastructure and greater public acceptance. In closing, this review highlights the promise of phage therapy as a critical backup or substitute for antibiotics. It proposes a new role as a significant adjunct to, or even replacement for, antibiotics in treating multidrug-resistant bacterial infections.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 1","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Babesia infection in cattle and dogs in Suizhou City, Hubei Province, China","authors":"Guandu Wu ,&nbsp;Xiaofan Zhou ,&nbsp;Fang Guo ,&nbsp;Jiao Xu ,&nbsp;Jingjing Song ,&nbsp;Zhen Jin ,&nbsp;Huijie Cao ,&nbsp;Ju Tang ,&nbsp;Huiya Lu ,&nbsp;Zezheng Jiang ,&nbsp;Tianmei Yu ,&nbsp;Xiaoyong Zhang ,&nbsp;Xiaohui Liu ,&nbsp;Xue-jie Yu","doi":"10.1016/j.imj.2025.100170","DOIUrl":"10.1016/j.imj.2025.100170","url":null,"abstract":"<div><h3>Background</h3><div>Babesiosis is a zoonotic disease caused by the intraerythrocytic parasite <em>Babesia</em>, which poses a serious threat to public health. Currently, the prevalence of babesiosis in domestic animals and the genetic diversity of <em>Babesia</em> in Central China have not been comprehensively studied.</div></div><div><h3>Methods</h3><div>In this study, we collected 1093 ticks, including 95.24% (1041/1093) <em>Haemaphysalis longicornis</em>, 4.67% (51/1093) <em>Rhipicephalus microplus,</em> and 0.09% (1/1093) <em>Ixodes sinensis</em>. Blood samples from 216 goats, 56 cattle, and 25 dogs were collected from Suizhou City, Hubei Province, China, and animal blood DNA was extracted for the detection of <em>Babesia</em> with PCR.</div></div><div><h3>Results</h3><div>PCR results showed that 50.00% (28/56) of cattle and 32.00% (8/25) of dogs were <em>Babesia</em>-positive, including for <em>Babesia bovis</em> 3.57% (2/56), <em>B. bigemina</em> 3.57% (2/56), and <em>B. ovata</em> 42.86% (24/56) in cattle and <em>B. gibsoni</em> 32.00% (8/25) in dogs. All goats (216) and ticks (1093) were <em>Babesia</em>-negative.</div></div><div><h3>Conclusions</h3><div>Our findings showed that <em>Babesia</em> infections are prevalent in cattle and dogs in Central China, indicating that babesiosis should be monitored in animals and humans in Central China.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 1","pages":"Article 100170"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of patients with coronavirus disease 2019 and active tuberculosis co-infection in Beijing China: A retrospective single-center descriptive study","authors":"Xinting Yang ,&nbsp;Chaohong Wang ,&nbsp;Yu Xue ,&nbsp;Yun Zhang ,&nbsp;Maike Zheng ,&nbsp;Qing Sun ,&nbsp;Sibo Long ,&nbsp;Da Wang ,&nbsp;Jun Yan ,&nbsp;Xinlei Liao ,&nbsp;Tiantian Zhang ,&nbsp;Lei Cao ,&nbsp;Yan Chen ,&nbsp;Wenfu Ju ,&nbsp;Jing Zhang ,&nbsp;Mengqiu Gao ,&nbsp;Yan Zhao ,&nbsp;Laurence Don Wai Luu ,&nbsp;Junhua Pan ,&nbsp;Yi Wang ,&nbsp;Guirong Wang","doi":"10.1016/j.imj.2025.100169","DOIUrl":"10.1016/j.imj.2025.100169","url":null,"abstract":"<div><h3>Background</h3><div>Coronavirus disease 2019 (COVID-19) and tuberculosis (TB) co-infection (COVID-19-TB) has the potential to exacerbate lung damage; however, information about the clinical features of COVID-19-TB is limited. This study aims to clarify the clinical characteristics and outcomes of patients with COVID-19-TB.</div></div><div><h3>Methods</h3><div>In this single-center retrospective study, the clinical features and outcomes of patients with COVID-19 with active TB who were admitted to Beijing Chest Hospital, Beijing, China, from 1 December 2022 to 18 January 2023 were collected. The severity of COVID-19 and TB was graded according to guidelines from the World Health Organization. The relationships of demographic and clinical variables with intensive care unit (ICU) admission were evaluated using univariable and multivariable logistic regression models.</div></div><div><h3>Results</h3><div>Overall, 102 patients with COVID-19-TB were enrolled. The mean age was 54.5 years (range 36.5–70 years). The most common clinical manifestations were cough (68.63%), sputum production (53.92%), fever (51.96%), and ground-glass opacities (35.29%). Complications included acute respiratory distress syndrome (11.76%), sepsis (9.8%), and respiratory failure (7.84%). Patients with COVID-19-TB had high concentrations of various proinflammatory cytokines, including interferon-γ, interleukin-1β, interferon-γ-inducible protein 10 kD, and monocyte chemoattractant protein-1. Sixteen of the 102 patients with COVID-19-TB (15.69%) were admitted to the ICU, and 10 (9.80%) died during hospitalization. The significant risk factors for ICU admission were respiratory failure, pulmonary fungal infection, and ventilation and oxygen therapy.</div></div><div><h3>Conclusions</h3><div>The mortality rate of COVID-19-TB was 9.80%. Several demographic and clinical characteristics were associated with adverse outcomes, indicating the importance of early recognition and treatment.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 1","pages":"Article 100169"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations","authors":"Bhumika Parashar ,&nbsp;Rishabha Malviya ,&nbsp;Sathvik Belagodu Sridhar ,&nbsp;Tarun Wadhwa ,&nbsp;Sirajunisa Talath ,&nbsp;Javedh Shareef","doi":"10.1016/j.imj.2025.100167","DOIUrl":"10.1016/j.imj.2025.100167","url":null,"abstract":"<div><div>Eastern equine encephalitis virus (EEEV) is a lethal <em>Alphavirus</em> transmitted by <em>Culiseta melanura</em> mosquitoes that primarily cycles between birds. Although rare, infections in humans and horses are associated with high mortality rates and severe neurological effects. Climate change appears to be increasing the spread of this virus. This study aims to provide a comprehensive analysis of EEEV, including its transmission dynamics, pathogenesis, induced host immune response, and long-term impacts on survivors. It also highlights the virus's unique immune evasion strategies that complicate disease management and contribute to severe clinical outcomes, such as encephalitis with fever, convulsions, and coma. Survivors often face chronic cognitive, motor, and psychosocial impairments. Despite these significant public health risks, gaps remain in understanding the molecular mechanisms underlying immune evasion and the long-term neurological sequelae in survivors. By collating current knowledge, this review underscores the urgent need for the development of targeted vaccines and therapeutic interventions to mitigate the growing threat of EEEV, particularly in the context of climate change-driven geographical expansion.</div></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 1","pages":"Article 100167"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Screening a neurotransmitter-receptor-related inhibitor library identifies clomipramine HCl as a potential antiviral compound against Japanese encephalitis virus” [Infectious Medicine 3 (2024) 100130]","authors":"Yixin Liu ,&nbsp;Xugang Wang ,&nbsp;Qi Li ,&nbsp;Shuo Zhu ,&nbsp;Wenjing Zhu ,&nbsp;Huanchun Chen ,&nbsp;Youhui Si ,&nbsp;Bibo Zhu ,&nbsp;Shengbo Cao ,&nbsp;Zikai Zhao ,&nbsp;Jing Ye","doi":"10.1016/j.imj.2024.100152","DOIUrl":"10.1016/j.imj.2024.100152","url":null,"abstract":"","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"4 1","pages":"Article 100152"},"PeriodicalIF":0.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}