IJID One Health最新文献

{"title":"A systematic review of fungi isolated from formalin-preserved human and animal cadavers: A potential health concern to exposed students and technicians","authors":"Richard Kwizera ,&nbsp;Joan Naluzze","doi":"10.1016/j.ijidoh.2024.100037","DOIUrl":"10.1016/j.ijidoh.2024.100037","url":null,"abstract":"<div><p>Fungal contamination of formalin-fixed cadavers raises potential health concerns. We aimed to systematically search published literature to explore the fungi that commonly contaminate formalin-fixed cadavers to estimate the size of the problem and all dynamics involved. Our search retrieved 20,273 citations and we retained eight descriptive cross-sectional studies that met our selection criteria, published between 2002 and 2022. The results indicate that, worldwide, there is a significant problem of fungal contamination in formalin-preserved cadavers. The majority of contaminated cadavers were human cadavers and only one citation studied animal cadavers. The formalin concentrations used in the tanks were 5–14 %. Studies mostly used swabs to collect samples and tested them using fungal culture. The fungi isolated included <em>Aspergillus spp, Penicillium spp, Trichophyton spp, Epidermophyton spp, Cryptococcus spp, Candida spp, Fusarium spp., Purpureocellium spp, Chrysonilia spp, Trichoderma spp, Microsporum spp,</em> and <em>Cladosporium spp</em>. The most suspected sources of contamination were air, water, and the bodies. <em>Aspergillus, Trichophyton</em>, and <em>Penicillium</em> species were the most common fungal contaminants isolated. Fungal contamination of cadavers can lead to financial loss and dangerous health outcomes for exposed individuals. The effective concentration of formalin remains unknown. Students/technicians should use personal protective equipment, such as face masks and gloves, while handling cadavers.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"4 ","pages":"Article 100037"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000210/pdfft?md5=0d28035fbd4af5f6f55941741fa70c9a&pid=1-s2.0-S2949915124000210-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual dysfunction and sudden onset symptoms leading to early detection of tick-borne infections: A case report","authors":"Ayra I. Sayyed ,&nbsp;William V. Padula","doi":"10.1016/j.ijidoh.2024.100036","DOIUrl":"10.1016/j.ijidoh.2024.100036","url":null,"abstract":"<div><h3>Objectives</h3><p>Tick-borne infections frequently impact the visual system; however, their symptoms are commonly misinterpreted as issues related to functional vision disorders, balance, movement, and cognition. Visual symptoms may include blurred vision, double vision, photosensitivity, perception of distorted space, visual strain, headaches during near vision activities, difficulties with balance, dizziness, reduced ability to bring the eyes together (convergence), inability to maintain focus, and inability to tolerate movement in peripheral vision.</p></div><div><h3>Case report</h3><p>This case report highlights a patient who presented with learning difficulties and behavioral issues. After a comprehensive neuro-optometric evaluation, specific ocular findings were observed, prompting suspicion of tick-borne disease. Subsequent comprehensive blood work for Lyme and associated diseases confirmed a diagnosis of tick-borne infection.</p></div><div><h3>Conclusion</h3><p>Early detection and diagnosis of tick-borne infections pose significant challenges. Often referred to as “the great mimicker,” these infections frequently result in misdiagnosis or redirection during the medical pursuit of a definitive diagnosis. Failure to diagnose and treat promptly during the acute phase may lead to chronic neurologic progression of the undiagnosed disease.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"4 ","pages":"Article 100036"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000209/pdfft?md5=4530fa641263d2a9816103eb38d4d7e8&pid=1-s2.0-S2949915124000209-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142098425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergence of the first molecularly confirmed outbreak of Rift Valley fever among humans in Rwanda, calls for institutionalizing the One Health strategy","authors":"Eric Remera ,&nbsp;Edson Rwagasore ,&nbsp;Claude M. Muvunyi ,&nbsp;Ayman Ahmed","doi":"10.1016/j.ijidoh.2024.100035","DOIUrl":"10.1016/j.ijidoh.2024.100035","url":null,"abstract":"<div><p>Here, we report the investigation, molecular confirmation, and response to the first outbreak of Rift Valley fever (RVF) among humans throughout the country in Rwanda in 2022. RVF is a mosquito-borne zoonotic arbovirus that is mainly prevalent in Africa. However, severely limited information is available about the disease among humans in the country. We confirmed 173 human cases of RVF, including 22 deaths, using molecular tools (polymerase chain reaction). Male patients were three times more frequently infected than females and most of the case were reported from the eastern borders of the country. The high case fatality rate (13 %) suggests delay in the detection and the provision of supportive case management; it could also be attributed to the possibility that the local population is naïve to the virus. This urges the implementation of a transdisciplinary One Health strategy for the preparedness, prevention, surveillance, and control of arboviruses and their vectors to protect humans and animals in the country. To successfully do this, additional evidence is needed to inform policy, national strategy, and guide the implementation of effective intervention. Therefore, we recommend further entomologic studies and genomics analysis to identify the competent vectors and characterize the virus and its dynamics in the region.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"4 ","pages":"Article 100035"},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000192/pdfft?md5=a9b1a758e9d8f03d8ea8959290195393&pid=1-s2.0-S2949915124000192-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141841889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of a One Health approach in preventing human Rift Valley fever infections in Uganda","authors":"Hildah Tendo Nansikombi ,&nbsp;Jane Frances Zalwango ,&nbsp;Alex Ndyabakira ,&nbsp;Benon Kwesiga ,&nbsp;Lilian Bulage ,&nbsp;Alex Riolexus Ario ,&nbsp;Julie R. Harris ,&nbsp;Irene Byakatonda Kyamwine ,&nbsp;Dan Tumusiime ,&nbsp;Fred Monje","doi":"10.1016/j.ijidoh.2024.100034","DOIUrl":"10.1016/j.ijidoh.2024.100034","url":null,"abstract":"<div><p>Rift valley fever (RVF) is an endemic viral zoonosis in Uganda that causes sporadic outbreaks. In May 2021, a 19-year-old woman from Kasaana Village, Kiruhura District, Western Uganda was diagnosed with RVF. In addition, five case patients identified from the same village were immunoglobulin (Ig) M–seropositive for RVF virus (RVFV), all with a history of contact with livestock. We interviewed farmers in Kasaana Village to find out whether their livestock had recently experienced any sign of RVF (livestock abortions and neonatal mortality). We conducted a veterinary records review at the regional animal diagnostic laboratory and a case search for livestock that had a recent history of abortion or neonatal mortality. Among 162 livestock (94 cattle and 68 goats) from four farms reporting one or more abortions during March-June 2021, 57 (33 cattle and 24 goats) were randomly selected for testing for RVFV using enzyme linked immunosorbent assay. Verbal reports from farmers and veterinary records review revealed increases in livestock abortions and neonatal mortality during March-May 2021, before the human cases occurred. Serological testing indicated that eight (14%) livestock, including three (9%) cattle and five (21%) goats, were IgM-seropositive for RVFV. The presence of anti-RVFV IgM antibodies in sera suggested current infection in livestock, corroborating livestock abortions within the same period. Hence, human RVFV infections likely resulted from contact with infected animal products. The recurring pattern of livestock abortions observed before human RVFV infections in Uganda indicates a gap in the zoonotic disease surveillance system, through which reports on such events should trigger rapid response to detect disease, control spread among animals, and prevent spillover to humans. An expanded One Health approach on collaboration and information sharing on such events could facilitate RVF risk reduction in humans in Uganda.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"4 ","pages":"Article 100034"},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000180/pdfft?md5=2dd7aeaca8a7754f5cb2325878cb7497&pid=1-s2.0-S2949915124000180-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141697974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 2023–2024 multi-source mpox outbreaks of Clade I MPXV in sub-Saharan Africa: Alarm bell for Africa and the World","authors":"Muge Cevik,&nbsp;Oyewale Tomori,&nbsp;Placide Mbala,&nbsp;Alessandra Scagliarini,&nbsp;Eskild Petersen,&nbsp;Nicola Low,&nbsp;David Heymann,&nbsp;Shui Shan Lee,&nbsp;Lucille Blumberg","doi":"10.1016/j.ijidoh.2024.100033","DOIUrl":"10.1016/j.ijidoh.2024.100033","url":null,"abstract":"","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"4 ","pages":"Article 100033"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000179/pdfft?md5=1318b85b2025819fe931881701d29652&pid=1-s2.0-S2949915124000179-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141959785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathogen genomics and One Health: A scoping review of current practices in zoonotic disease research","authors":"Stefano Catalano ,&nbsp;Francesca Battelli ,&nbsp;Zoumana I. Traore ,&nbsp;Jayna Raghwani ,&nbsp;Christina L. Faust ,&nbsp;Claire J. Standley","doi":"10.1016/j.ijidoh.2024.100031","DOIUrl":"https://doi.org/10.1016/j.ijidoh.2024.100031","url":null,"abstract":"<div><h3>Objectives</h3><p>Whole-genome sequencing has revolutionized the field of infectious disease surveillance, enabling near real-time detection of pathogens and tracking how infections may spread. Our study aimed to characterize genomic applications to cross-domain zoonotic pathogen transmission at the human-animal and/or human-environment interfaces.</p></div><div><h3>Methods</h3><p>We performed a scoping review of studies that have applied genomic epidemiology to zoonotic disease transmission across One Health domains (human, animal, and environment). We identified 114 records published between 2005 and 2022 which reported multi-domain genomic data of zoonotic pathogens integrated into phylogenetic models.</p></div><div><h3>Results</h3><p>Most studies investigated bacterial pathogens, highlighting key knowledge gaps for other zoonotic agents, particularly arboviruses. Sampling and sequencing efforts varied greatly across domains: the median number and range of pathogen genomes analyzed were highest for humans (23; 1–29,586) and lowest for the environment domain (13; 1–956). Genomics was used to track zoonotic disease outbreaks and cross-domain transmission, to improve pathogen surveillance, and to disentangle evolutionary dynamics driving lineage diversification and virulence.</p></div><div><h3>Conclusions</h3><p>Our study highlights current practices and knowledge gaps to guide future study designs and genomic applications to multi-domain and cross-species transmission of zoonoses, with the potential to identify key infection sources and inform interventions for local and global health security.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"4 ","pages":"Article 100031"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000155/pdfft?md5=0def9be97e4e98b20ab1aa9f23b792fd&pid=1-s2.0-S2949915124000155-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141540411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unprecedented rabies outbreak in Nepal’s Far Western Region: A call for urgent action","authors":"Sameer Thakur ,&nbsp;Naresh Prasad Joshi ,&nbsp;Bishal Chand ,&nbsp;Lokendra Neupane","doi":"10.1016/j.ijidoh.2024.100027","DOIUrl":"10.1016/j.ijidoh.2024.100027","url":null,"abstract":"<div><p>Rabies, a zoonotic disease caused by lyssaviruses, poses a severe and escalating threat in the Far Western Region of Nepal. The recent outbreak of rabies in the Kailali and Kanchanpur districts of Sudurpaschim province has reached unprecedented levels, with a 92.30 % positivity rate in suspected samples. Within a year, there have been 84 confirmed outbreaks, with 32 in Kailali and 50 in Kanchanpur, highlighting the seriousness of the situation in these districts. This outbreak has also affected various animal species, including pigs, marking the first case in Nepal, and also caused the death of a young boy due to rabies. Given the historically low number of rabies cases in the province, the current situation is highly alarming and necessitates immediate government intervention. The challenges faced include the absence of a comprehensive national rabies control policy, limited resources, and inadequate awareness in rural areas. To effectively address this crisis, urgent action is required, which entails a multidisciplinary approach, collaboration between government and non-governmental organizations, prioritization of rural areas, improvement of health infrastructure, and strengthened surveillance.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"4 ","pages":"Article 100027"},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000118/pdfft?md5=97f06ace302fefa0fb15a1856da256f9&pid=1-s2.0-S2949915124000118-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avian ‘Bird’ Flu – Undue media panic or genuine concern for pandemic potential requiring global preparedness action?","authors":"Eskild Petersen ,&nbsp;Ziad A. Memish ,&nbsp;David S. Hui ,&nbsp;Alessandra Scagliarini ,&nbsp;Lone Simonsen ,&nbsp;Edgar Simulundu ,&nbsp;Jennifer Bloodgood ,&nbsp;Lucille Blumberg ,&nbsp;Shui-Shan Lee ,&nbsp;Alimuddin Zumla","doi":"10.1016/j.ijidoh.2024.100020","DOIUrl":"10.1016/j.ijidoh.2024.100020","url":null,"abstract":"","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"3 ","pages":"Article 100020"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000040/pdfft?md5=b3969c5db650a16f9591b31c29ce2faf&pid=1-s2.0-S2949915124000040-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140769548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First report of prosthetic joint infection due to Mycoplasma capricolum","authors":"Lucia Henriquez ,&nbsp;Iñaki Beguiristain ,&nbsp;Carmen Ezpeleta ,&nbsp;María Eugenia Portillo","doi":"10.1016/j.ijidoh.2024.100022","DOIUrl":"https://doi.org/10.1016/j.ijidoh.2024.100022","url":null,"abstract":"<div><p><em>Mycoplasma capricolum</em> is a pathogen almost exclusively found in goats, which causes contagious caprine pleuropneumonia, a highly contagious respiratory disease of small ruminants. Herein, we report the first case of prosthetic joint infection (PJI) caused by <em>M. capricolum.</em> The patient was a goat herder who had been implanted with a total knee prosthesis 9 years earlier. He presented to the emergency department with fever and swelling in the knee. A biochemical analysis of the joint fluid was highly suggestive of a PJI but the culture remained negative for bacteriological and mycobacterial growth. The patient was discharged with a diagnosis of inflammatory knee osteoarthritis; however 2 weeks later, the patient was referred to the emergency department again due to joint effusion. Small unidentifiable pinpoint-sized colonies grew on the chocolate agar medium from the joint fluid and blood samples after more than 1 week of incubation. Application of 16S ribosomal RNA gene sequencing to the colonies was able to identify the organism as <em>M. capricolum</em>. To the best of our knowledge, this is the first case of <em>M. capricolum</em> PJI, and it highlights the utility of using molecular methods in diagnosing implant-associated infections.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"3 ","pages":"Article 100022"},"PeriodicalIF":0.0,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000064/pdfft?md5=f296556d3bffb5a3b7705aa9c5114e04&pid=1-s2.0-S2949915124000064-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141067730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological study of the 2023 Crimean-Congo hemorrhagic fever outbreak in Iraq","authors":"Dana Khdr Sabir ,&nbsp;Shako M. Mohammad ,&nbsp;Nabaz R. Khwarahm ,&nbsp;Sehand Kamaluldeen Arif ,&nbsp;Bana Azad Tawfeeq","doi":"10.1016/j.ijidoh.2024.100017","DOIUrl":"10.1016/j.ijidoh.2024.100017","url":null,"abstract":"<div><h3>Objectives</h3><p>Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne virus disease that is of a high concern for global health care systems because there is no specific treatment or vaccination available for it yet. The disease is endemic in several countries around the world and humans can get infected with the virus through the tick bites or by coming into contact with tissues or blood of the infected animals. This study aimed to describe the epidemiology of the disease in Iraq from January 1, 2023 to June 18, 2023.</p></div><div><h3>Methods</h3><p>This is a retrospective study and the epidemiological data of CCHF in Iraq within the first 6 months of 2023 were kindly provided by the Sulaymaniyah directory of the World Health Organization/Iraq.</p></div><div><h3>Results</h3><p>Overall, 229 CCHF cases and 36 deaths were recorded during this study. The majority of the cases were aged between 15 and 45 years, and the gender distribution ratio of males to females was 61% and 39%, respectively.</p></div><div><h3>Conclusions</h3><p>CCHF is an extremely severe disease that poses a threat to the public health. The hyper-endemic status of CCHF in Iraq is continuing and the number of cases has increased in 2023 compared with 2022.</p></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"2 ","pages":"Article 100017"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949915124000015/pdfft?md5=28b0991fb4badfad98ed430d2f78ae1d&pid=1-s2.0-S2949915124000015-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}