iGIE最新文献

{"title":"A note from the Editor-in-Chief: a time of gratitude","authors":"Linda S. Lee MD, FACG, FASGE","doi":"10.1016/j.igie.2026.02.001","DOIUrl":"10.1016/j.igie.2026.02.001","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Page 1"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastric peroral endoscopic pyloromyotomy as an effective treatment for symptomatic delayed gastric emptying after Ivor Lewis esophagectomy","authors":"Tarek Nammour MD ,&nbsp;Makoto Nishimura MD ,&nbsp;Natalia Zbib MD ,&nbsp;Seung Eun Lee MD ,&nbsp;Sayaka Nagao MD ,&nbsp;Mako Koseki MD ,&nbsp;Daniela Molena MD ,&nbsp;David R. Jones MD ,&nbsp;Hans Gerdes MD ,&nbsp;Jacques Beauvais MD ,&nbsp;Mark Schattner MD","doi":"10.1016/j.igie.2025.09.005","DOIUrl":"10.1016/j.igie.2025.09.005","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Delayed gastric emptying (DGE) is a frequent adverse event after Ivor Lewis esophagectomy, negatively affecting quality of life. Although gastric peroral endoscopic pyloromyotomy (G-POEM) is effective for gastroparesis, its role in postesophagectomy DGE remains uncertain. This study evaluates the feasibility and outcomes of G-POEM in this setting.</div></div><div><h3>Methods</h3><div>We conducted a single-center retrospective analysis of 11 patients who underwent G-POEM after Ivor Lewis esophagectomy, all of whom had symptomatic DGE confirmed by gastric-emptying studies and Gastroparesis Cardinal Symptom Index scores.</div></div><div><h3>Results</h3><div>All patients had confirmed DGE, with a median 49% (interquartile range, 24-80) gastric retention at 4 hours on gastric-emptying studies (normal is ≤10% retention at 4 hours). After G-POEM, gastric emptying normalized in 50% of patients and improved in 37.5%, with a median retention of 13% (0-75) at 4 hours. The median Gastroparesis Cardinal Symptom Index score improved from 25 (11-33) to 11 (2-33), where a score of 0 indicates no symptoms. Prokinetic use declined from 45.5% to 9.1%. The median procedure time was 68 (33-110) minutes, hospital stay was 1 (1-5) day, and no immediate adverse events were reported.</div></div><div><h3>Conclusions</h3><div>G-POEM appears to be a feasible and safe treatment for DGE after Ivor Lewis esophagectomy, associated with early symptomatic improvement and minimal hospital stay although further prospective studies are needed.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 9-12"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastric peroral endoscopic myotomy for compassionate treatment of symptomatic gastroparesis in patients on chronic opioids","authors":"Maham Hayat MD ,&nbsp;Abel Joseph MD ,&nbsp;Yasi Xiao MD ,&nbsp;Abdullah Abbasi MD ,&nbsp;Saurabh Chandan MD ,&nbsp;Sagar Pathak MD ,&nbsp;Baha Aldeen Bani Fawwaz MD ,&nbsp;Aimen Farooq MD ,&nbsp;Natalie Cosgrove MD ,&nbsp;Deepanshu Jain MD ,&nbsp;Mustafa A. Arain MD ,&nbsp;Kambiz Kadkhodayan MD ,&nbsp;Ernesto R. Gonzaga MD ,&nbsp;Irteza Inayat MD ,&nbsp;Muhammad K. Hasan MD ,&nbsp;Joo Ha Hwang MD ,&nbsp;Dennis Yang MD","doi":"10.1016/j.igie.2025.05.001","DOIUrl":"10.1016/j.igie.2025.05.001","url":null,"abstract":"<div><h3>Background and Aims</h3><div>It has been estimated that nearly half of patients with gastroparesis use opioids long term, are unable to cease or wean opioid use, and continue to endorse debilitating symptoms. The aim of this study was to evaluate outcomes of gastric peroral endoscopic myotomy (G-POEM) as compassionate treatment in patients with gastroparesis who are unable to discontinue long-term opioid use.</div></div><div><h3>Methods</h3><div>This was a multicenter retrospective analysis of prospective databases containing patients with gastroparesis taking opioids who underwent G-POEM between January 2021 and November 2024. Functional luminal imaging probe (FLIP) pyloric measurements were obtained pre- and post-G-POEM at follow-up. Clinical response to G-POEM was defined as improvement of ≥1 point on the Gastroparesis Cardinal Symptom Index.</div></div><div><h3>Results</h3><div>Thirty-eight patients with gastroparesis on opioids with a median follow-up of 6 months (range, 3-18 months) underwent G-POEM during the study period. Technical success was 100%. Clinical success was achieved in 60.5% (23/38) of the patients. There were no differences in demographics, symptom duration, etiology of gastroparesis, baseline Gastroparesis Cardinal Symptom Index score, gastric-emptying scintigraphy or daily morphine milligram equivalent between responders and nonresponders. When compared with nonresponders, patients who responded to G-POEM had a significantly lower FLIP baseline pyloric diameter (13.2 [standard deviation (SD) 3.4 mm² ] vs 15.6 [SD 2.7 mm²]; <em>P</em> = .04) and distensibility index (4.8 [SD 1.9 mm²/mm Hg] vs 8.4 [SD 4.6 mm²/mm Hg]; <em>P</em> = .004). Clinical response was associated with improvement in FLIP pyloric diameter and distensibility index.</div></div><div><h3>Conclusions</h3><div>This study suggests that G-POEM could be considered as a safe and effective compassionate treatment in select patients with gastroparesis who are taking opioids long term, particularly those with lower pyloric compliance on physiologic testing. Future studies are needed to corroborate these preliminary findings.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 13-20"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenoma detection rates during screening colonoscopy performed by interventional gastroenterologists and general gastroenterologists","authors":"Jordan Burlen MD ,&nbsp;Stacey Culp PhD ,&nbsp;Michelle Messer BS ,&nbsp;Peter P. Stanich MD ,&nbsp;Georgios Papachristou MD ,&nbsp;Somashekar Krishna MD ,&nbsp;Samuel Han MD ,&nbsp;Royce Groce MD ,&nbsp;Sajid Jalil MD ,&nbsp;Peter Lee MB, BCh ,&nbsp;Hamza Shah DO ,&nbsp;Luis Lara MD","doi":"10.1016/j.igie.2025.12.006","DOIUrl":"10.1016/j.igie.2025.12.006","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Interventional gastroenterologists typically perform colonoscopies at lower volumes than general gastroenterologists, and we sought to determine whether this disparity affects their overall adenoma detection rates (ADRs). Our study aimed to identify any difference in ADR between interventional gastroenterologists and general gastroenterologists.</div></div><div><h3>Methods</h3><div>A retrospective cohort study from January 2020 to January 2023 was performed to determine ADRs for interventional gastroenterologists and general gastroenterologists at a single academic tertiary care center, as well as assessing for other quality indicators of screening colonoscopy.</div></div><div><h3>Results</h3><div>We reviewed 9755 screening colonoscopies. On univariate analysis, ADR differed between groups (46.9% vs 41.5%, <em>P</em> = .033), but on multivariate analysis, provider type was not associated with ADR (odds ratio = 0.99; 95% confidence interval, 0.80-1.22; <em>P</em> = .919).</div></div><div><h3>Conclusions</h3><div>ADR was similar between interventional and general gastroenterologists after adjustment for patient characteristics, supporting inclusion of interventional gastroenterologists in colorectal cancer screening practices.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 37-40.e1"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"User, expert, and construct validation of a new colonoscopy simulator: correlation with National Endoscopy Database key performance indicators","authors":"Olaolu Olabintan MBBS, MRCP ,&nbsp;Adeyeye Ademola MBBS, FRCS ,&nbsp;Mabel Tanne iBSc ,&nbsp;Homira Ayubi MBBS, MRCP ,&nbsp;Ali Eqbal MBBS, FRACP ,&nbsp;Mehul Patel MBBS, MRCP, PhD ,&nbsp;Andrew Emmanuel MBBS, FRCS, PhD ,&nbsp;Shraddha Gulati MBBS, MRCP, PhD ,&nbsp;Amyn Haji MD, FRCS, FASGE ,&nbsp;Bu’Hussain Hayee PhD, FRCP, FASGE","doi":"10.1016/j.igie.2025.08.007","DOIUrl":"10.1016/j.igie.2025.08.007","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Training in flexible gastrointestinal endoscopy is increasingly challenging. Simulation tools may help impart essential skills, but existing simulators lack real-time feedback, may be unrealistic, and are not aligned with recognized key performance indicators (KPIs). As a result, translating from simulator to real-world procedures has achieved variable outcomes. The Mikoto colonoscopy simulator (R Zero Inc, Tokyo, Japan) aims to address this gap by providing real-time feedback based on procedural dynamics, including patient comfort, producing a single performance-focused score (out of a maximum possible 100; the Mikoto Simulator Score [MSS]).</div><div>We sought to establish construct and user validation for the MSS, with endoscopists' KPIs and structured user feedback.</div></div><div><h3>Methods</h3><div>Twenty endoscopists of varying experience levels were recruited and categorized into novice, training, competent, and expert experience levels, based on lifetime colonoscopy numbers (national accreditation criteria). Participants provided their United Kingdom National Endoscopy Database (NED) KPIs before using the simulator. After standardized introduction and acclimatization, each then performed 3 full colonoscopies on the simulator, with the main test parameters being cecal intubation time and MSS. User validity was determined by means of a structured feedback questionnaire assessing utility and realism.</div></div><div><h3>Results</h3><div>Significant differences were observed in median NED KPIs and MSS across all experience levels (n = 5 in each group, <em>P</em> = .046), with a linear correlation between lifetime colonoscopy numbers and MSS (<em>P</em> = .027). There were also highly significant correlations demonstrated between MSS and NED colonoscopy comfort score (<em>P</em> &lt; .001), polyp detection rate (<em>P</em> &lt; .001), and cecal intubation rate (<em>P</em> &lt; .001).</div></div><div><h3>Conclusions</h3><div>The Mikoto simulator demonstrates close alignment with NED KPIs for colonoscopy, with linear correlation in most cases, providing initial validation as an indicator of endoscopic competence in a nonpatient-contact setting. Further studies are warranted to assess integration into endoscopy training. The Mikoto simulator represents a promising tool for enhancing endoscopic training and improving patient outcomes.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 2-8.e1"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare case of a bronchogenic cyst at the distal esophagus","authors":"Brian Xu MD ,&nbsp;Saurabh Chawla MD ,&nbsp;Gabriela Oprea-Ilies MD ,&nbsp;Emad Qayed MD, MPH","doi":"10.1016/j.igie.2025.08.004","DOIUrl":"10.1016/j.igie.2025.08.004","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 57-58"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Signet ring adenocarcinoma of the breast diagnosed endoscopically","authors":"Michael Hayes MBChB,&nbsp;John Ahn MBChB,&nbsp;Cameron Schauer MBChB","doi":"10.1016/j.igie.2025.08.002","DOIUrl":"10.1016/j.igie.2025.08.002","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 55-56"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic ultrasound–guided coil embolization and absorbable hemostatic gelatin sponge is a safe and efficacious treatment for bleeding rectal varices","authors":"Kanwal Bains MD ,&nbsp;Thomas J. Wang MD ,&nbsp;Marvin Ryou MD","doi":"10.1016/j.igie.2025.08.009","DOIUrl":"10.1016/j.igie.2025.08.009","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Rectal variceal bleeding is a rare life-threatening cause of lower gastrointestinal bleeding. We present the first case series to our knowledge of successful hemostasis achieved with combination of endoscopic ultrasound (EUS)-guided coil embolization and absorbable gelatin sponge (AGS) for bleeding rectal varices.</div></div><div><h3>Methods</h3><div>We performed a retrospective review of 6 patients with active rectal variceal bleeding. All patients underwent EUS-guided coil embolization with AGS therapy. Procedural details, technical success, adverse events, and rebleeding rates were measured.</div></div><div><h3>Results</h3><div>We achieved 100% technical success (6 of 6 patients) with successful sonographic rectal varices decompression. A range of 1 to 4 coils with a total length of 7 to 20 cm was injected along with AGS. There were no adverse events or rebleeding from recurrent rectal varices. Median follow-up period was 190 days.</div></div><div><h3>Conclusions</h3><div>EUS-guided coiling coupled with AGS therapy appears to be a potentially safe and efficacious alternative for patients with bleeding rectal varices.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 70-74"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From screening to resection: innovation in the treatment of anorectal high-grade squamous intraepithelial lesion in high-risk patients","authors":"Sofia Bragança MD ,&nbsp;Paula Borralho Nunes MD, PhD ,&nbsp;Sandra Pires MD ,&nbsp;Luís Carvalho Lourenço MD","doi":"10.1016/j.igie.2025.08.003","DOIUrl":"10.1016/j.igie.2025.08.003","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 52-54"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cowden syndrome gastrointestinal polyposis","authors":"Vitchapong Prasitsumrit MD ,&nbsp;Tinpawee Thongkongthun MD ,&nbsp;Rome Jutabha MD","doi":"10.1016/j.igie.2025.06.005","DOIUrl":"10.1016/j.igie.2025.06.005","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 1","pages":"Pages 48-49"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147570715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}