iGIE最新文献

{"title":"Single-operator cholangioscopy in the diagnosis and treatment planning of hilar intraductal papillary neoplasia of the bile duct: a case report","authors":"Dario Gambaccini MD,&nbsp;Filippo Ovidi MD,&nbsp;Delio Stefani Donati MD,&nbsp;Veronica Natali MD,&nbsp;Arianna Venturini MD,&nbsp;Gherardo Tapete MD,&nbsp;Valeria Bolognesi MD,&nbsp;Andrea Pancetti MD,&nbsp;Pierfrancesco Visaggi MD,&nbsp;Antonio Grosso MD,&nbsp;Emanuele Marciano MD","doi":"10.1016/j.igie.2026.03.003","DOIUrl":"10.1016/j.igie.2026.03.003","url":null,"abstract":"<div><div>A 53-year-old man presented with abdominal pain and cholestasis with normal bilirubin. Computed tomography and magnetic resonance imaging/magnetic resonance cholangiopancreatography suggested a perihilar stricture but could not exclude left-duct extension, and initial multidisciplinary review deemed the case unresectable. Endoscopic retrograde cholangiopancreatography with peroral single-operator cholangioscopy (SOC) obtained biopsy specimens, but the stricture was not traversable; repeat multidisciplinary review pursued antegrade mapping. A left percutaneous transhepatic drain was placed; 11 days after percutaneous drain placement, antegrade percutaneous SOC (pSOC) mapped right duct involvement and confirmed left hepatic duct sparing, revising resectability. The patient underwent associating liver partition and portal vein ligation for staged hepatectomy followed by extended right hepatectomy. Pathology showed intraductal papillary neoplasm of the bile duct with high-grade dysplasia and microscopically negative margins (R0); no adverse events occurred. Combined peroral and pSOC can enable curative surgery when imaging and endoscopic retrograde cholangiopancreatography are inconclusive.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 424-427"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Same-day discharge after duodenal endoscopic submucosal dissection and hybrid endoscopic submucosal dissection: a case series of 10 patients","authors":"Sayaka Nagao MD, PhD,&nbsp;Makoto Nishimura MD,&nbsp;Monika Laszkowska MD,&nbsp;Mako Koseki MD,&nbsp;Laura Tang MD, PhD,&nbsp;Mark A. Schattner MD","doi":"10.1016/j.igie.2026.01.013","DOIUrl":"10.1016/j.igie.2026.01.013","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Duodenal endoscopic submucosal dissection (ESD) involves postprocedural hospitalization owing to concerns about delayed adverse events. The safety of same-day discharge (SDD) after duodenal ESD remains unexplored. This case series reports clinical outcomes of patients undergoing SDD after duodenal ESD.</div></div><div><h3>Methods</h3><div>This case series included 10 patients receiving SDD after duodenal ESD at a tertiary referral center.</div></div><div><h3>Results</h3><div>Ten patients (5 males) with a mean (standard deviation) age of 62.6 (12.4) years were included. Mean resection size and procedure time were 12.5 (4.5) mm and 66.5 (32.3) minutes, respectively. Complete mucosal defect closure was achieved using endoscopic clips in all patients. No intraoperative or delayed adverse events were observed.</div></div><div><h3>Conclusions</h3><div>SDD appears safe in carefully selected patients with small lesions undergoing duodenal ESD by experienced endoscopists. These findings provide initial evidence supporting the consideration of SDD after duodenal ESD, although larger studies are needed to establish standardized protocols.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 440-444"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stent ligation to avoid stent migration into the common bile duct in a case of choledocholithiasis","authors":"Kazuki Ikeda MD, PhD,&nbsp;Yoko Sakamoto MD, PhD,&nbsp;Aya Takahashi MD, PhD,&nbsp;Maki Inai MD, PhD,&nbsp;Yoshitaka Konda MD, PhD,&nbsp;Tsutomu Chiba MD, PhD","doi":"10.1016/j.igie.2026.01.007","DOIUrl":"10.1016/j.igie.2026.01.007","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 374-375"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The spontaneous expulsion of a large colonic lipoma: a rare case","authors":"Shamira Ghouse MRCP,&nbsp;Emanuelle Suratos BSc,&nbsp;Dee-Ann Davies C&G Cert,&nbsp;Rajiv Swamy FRCPath,&nbsp;Carolina Lopez FRCR,&nbsp;Vivek Gupta FRCS,&nbsp;Sabina Beg PhD","doi":"10.1016/j.igie.2026.01.008","DOIUrl":"10.1016/j.igie.2026.01.008","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 376-377"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monorail technique for retrieval of a proximally migrated pancreatic stent","authors":"Karthik Chandrasekaran MD,&nbsp;Hiroyuki Isayama MD,&nbsp;Bashar Qumseya MD,&nbsp;Peter V. Draganov MD","doi":"10.1016/j.igie.2026.01.020","DOIUrl":"10.1016/j.igie.2026.01.020","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 384-385"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic ultrasound–guided tandem dual-modality ablation case report: a novel approach for managing branch duct intraductal papillary mucinous neoplasms","authors":"Vanisha Patel MD,&nbsp;Fadi Hawa MD,&nbsp;Erica Park MD,&nbsp;Somashekar G. Krishna MD, MPH","doi":"10.1016/j.igie.2025.12.001","DOIUrl":"10.1016/j.igie.2025.12.001","url":null,"abstract":"<div><div>Endoscopic ultrasound (EUS)-guided radiofrequency ablation (EUS-RFA) and chemoablation are nonsurgical options for managing pancreatic cystic lesions. Prior studies do not provide evidence-based escalation pathways for nonresponders to single-modality therapy. This case highlights a novel approach to managing branch duct intraductal papillary mucinous neoplasms (BD-IPMNs) using a combination of EUS-RFA and chemoablation to treat a 50- × 39-mm BD-IPMN. Our strategy integrated EUS-guided needle-based confocal laser endomicroscopy and cyst fluid molecular analysis via next-generation sequencing for accurate diagnosis and risk stratification. We demonstrate the effectiveness of tandem approach, not planned a priori, in which EUS-RFA elicited a partial response, followed by salvage chemoablation that achieved complete cyst resolution. The patient developed mild acute pancreatitis after chemoablation, which did not require hospitalization. This case underscores the potential for further investigation of multimodal ablative therapy for large BD-IPMNs in patients who are poor surgical candidates.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 407-410"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel endoscopic guidewire—assisted transection for removal of an embedded pediatric foreign body: a case report","authors":"Courtney Svenstrup MD,&nbsp;Barrett P. Cromeens DO, PhD,&nbsp;Payton M. Miller MD,&nbsp;Brett J. Hoskins DO","doi":"10.1016/j.igie.2025.10.011","DOIUrl":"10.1016/j.igie.2025.10.011","url":null,"abstract":"<div><div>Pediatric foreign body ingestion is common, but endoscopic removal can be challenging when objects become embedded. We report a novel, nonthermal, guidewire-assisted transection technique to release a metallic carabiner anchored at the pylorus/duodenum by a mucosal bridge. A 13-year-old boy with autism presented 2 weeks after ingestion. Radiographs showed the object unchanged in the stomach over serial imaging. Endoscopy revealed the carabiner fixed at the pylorus, where its spring-loaded gate had closed over a mucosal fold, creating a tissue bridge. A 0.035-inch curved-tip guidewire was looped beneath the bridge and tensioned in a reciprocating motion, mechanically transecting the tissue and freeing the object. A vascular sheath protected the upper gastrointestinal tract during manipulation. The resulting mucosal defect was closed with 5 hemostatic clips, and the patient recovered uneventfully with normal fluoroscopic follow-up imaging. This novel approach avoided surgery and illustrates how device-adapted endoscopic strategies can expand therapeutic options in pediatrics.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 396-401"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re-evaluating the role of magnifying endoscopy in postendoscopic submucosal dissection vessel detection","authors":"Yusuf Bünyamin Ketenci MD,&nbsp;Müge Ustaoğlu Dede MD","doi":"10.1016/j.igie.2026.03.006","DOIUrl":"10.1016/j.igie.2026.03.006","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Page 501"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic ultrasound–directed transenteric endoscopic retrograde cholangiopancreatography using antegrade hepaticogastrostomy-assisted saline instillation in Roux-en-Y anatomy: a case report","authors":"Timothy Adam MD,&nbsp;Michiel Bronswijk MD,&nbsp;Jan Vandewalle MD,&nbsp;Giuseppe Vanella MD, PhD,&nbsp;Enrique Pérez-Cuadrado-Robles MD, PhD,&nbsp;Roy L.J. van Wanrooij MD, PhD,&nbsp;Schalk Van der Merwe MD, MSc, PhD","doi":"10.1016/j.igie.2025.11.002","DOIUrl":"10.1016/j.igie.2025.11.002","url":null,"abstract":"<div><div>Endoscopic ultrasound (EUS)-directed transenteric endoscopic retrograde cholangiopancreatography (EDEE) has become a valuable therapeutic option in patients with nongastric bypass anatomy requiring biliary access. However, adequate afferent loop access can be challenging. Our aim was to illustrate an alternative way of achieving small-bowel distention during EDEE in a patient with recurrent cholangitis due to strictures of both the left- and right-sided bilioenteric anastomosis. We used a temporary EUS-guided hepaticogastrostomy to provide antegrade afferent loop access, facilitating on-demand saline instillation and small-bowel distention. Antegrade catheter–based saline instillation provided adequate afferent loop distention and stabilization for the creation of an enteroenteric anastomosis with a lumen-apposing metal stent (LAMS). This allowed for adequate through-the-LAMS endoscopic retrograde cholangiopancreatography and stricture management in nongastric bypass Roux-en-Y anatomy. We concluded that antegrade hepaticogastrostomy–assisted saline instillation might be useful in patients undergoing EDEE where classic approaches to afferent loop distention have failed.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 402-406"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peroral plication of esophagus for end-stage achalasia: a systematic review","authors":"Fouad Jaber MD, MS,&nbsp;Isiah Gonzalez MD,&nbsp;Bryan Luu MD,&nbsp;Leo Kleyman MD,&nbsp;Jacob R. Moremen MD,&nbsp;Wasseem Skef MD","doi":"10.1016/j.igie.2026.01.014","DOIUrl":"10.1016/j.igie.2026.01.014","url":null,"abstract":"<div><h3>Background and Aims</h3><div>End-stage achalasia is marked by persistent symptoms even after lower esophageal sphincter (LES)-directed therapies and may require esophagectomy, which is associated with significant adverse events. Peroral plication of the esophagus (POPE) is a novel minimally invasive, intermediate alternative. This review aimed to assess the safety and efficacy of POPE in treating end-stage achalasia.</div></div><div><h3>Methods</h3><div>A systematic search was performed in PubMed, Embase, Web of Science, and the Cochrane Library from January 2016 to May 2025 for studies on POPE in end-stage achalasia. Primary outcomes included clinical success, defined as symptom improvement. Secondary outcomes were technical success, adverse events, need for repeat POPE, or esophagectomy. Continuous variables were summarized as means with standard deviations, whereas categorical variables were reported as pooled proportions.</div></div><div><h3>Results</h3><div>Four studies including 45 patients with end-stage achalasia were analyzed. The cohort included 21 males (46.7%), with subtypes reported in 2 studies: 17 type I, 13 type II, and unknown or unreported subtypes (n = 15). Prior durable LES interventions included peroral endoscopic myotomy (n = 21), pneumatic dilation (n = 19), and Heller myotomy (n = 17). Regurgitation (75%) and dysphagia (65%) were the 2 most common symptoms. Pooled technical success was 100% (45/45), and pooled clinical success was 90% (37/41). Symptom improvement was observed across studies using Eckardt, gastroesophageal reflux disease Health-Related Quality of Life (GERD-HRQL), and Reflux Symptom Index scores. Eight patients required repeat POPE, and no patients underwent esophagectomy. Adverse events were observed in 7 patients (15.7%), including 2 cases of bleeding, 3 mucosal perforations, 1 readmission for pain, and 1 instance of aspiration pneumonia occurring 2 weeks after a second POPE procedure. All adverse events were managed conservatively, and no deaths were reported.</div></div><div><h3>Conclusions</h3><div>POPE may offer a minimally invasive option for selected patients with end-stage achalasia and persistent symptoms after LES-directed therapy, but high rates of repeat procedures and considerable adverse events raise concerns about durability and safety. Larger long-term prospective studies are needed to clarify its true efficacy, safety, and ideal patient candidates.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 448-456.e4"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}