Headache Currents最新文献_第3页

Migraine and Vertigo: Epidemiology, Genetics, and Mechanism(s) 偏头痛和眩晕:流行病学、遗传学和机制

Headache Currents Pub Date : 2006-03-28 DOI: 10.1111/j.1743-5013.2006.00025.x

Robert W. Baloh M.D.

{"title":"Migraine and Vertigo: Epidemiology, Genetics, and Mechanism(s)","authors":"Robert W. Baloh M.D.","doi":"10.1111/j.1743-5013.2006.00025.x","DOIUrl":"10.1111/j.1743-5013.2006.00025.x","url":null,"abstract":" Both migraine and vertigo are highly prevalent in the general population, but the co-occurrence of migraine and vertigo is much higher than would be expected by chance alone with a lifetime prevalence of migrainous vertigo in the range of 1%. Genetic factors are important for determining the threshold for migraine symptoms but so far, mutations have been identified in only two genes for the relatively rare syndrome of familial hemiplegic migraine. Numerous genetic loci and candidate genes have been identified for the more common syndromes of migraine with aura and migraine without aura, but the results are conflicting and largely unreplicated. Recently, a susceptibility locus for familial benign recurrent vertigo was identified on chromosome 22q, but as with the susceptibility loci for migraine syndromes, this will need to be replicated in other patient populations. How migraine leads to recurrent vertigo is poorly understood; there may be multiple mechanisms affecting both peripheral and central vestibular pathways. Vasospasm involving the labyrinthine arteries is an intriguing possibility since vasospasm has been identified with retinal migraine. An ion channel mutation shared by ear and brain could explain the combination of central and peripheral vestibular signs and the common triggers for migraine symptoms. Finally, in some patients with migrainous vertigo, the inner ear may be damaged resulting in a form of Meniere's disease. ","PeriodicalId":100600,"journal":{"name":"Headache Currents","volume":"3 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2006-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1743-5013.2006.00025.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90077583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Migraine and Vertigo: Classification, Clinical Features, and Special Treatment Considerations 偏头痛和眩晕:分类、临床特征和特殊治疗注意事项

Headache Currents Pub Date : 2006-03-28 DOI: 10.1111/j.1743-5013.2006.00027.x

Thomas Brandt M.D., F.R.C.P., Michael Strupp M.D.

{"title":"Migraine and Vertigo: Classification, Clinical Features, and Special Treatment Considerations","authors":"Thomas Brandt M.D., F.R.C.P., Michael Strupp M.D.","doi":"10.1111/j.1743-5013.2006.00027.x","DOIUrl":"10.1111/j.1743-5013.2006.00027.x","url":null,"abstract":" Vestibular migraine is a recognized medical entity in most dizziness units. It accounts for approximately 10% of these ‘dizzy’ patients and is the most common cause of spontaneous episodic vestibular vertigo. In about one third of the patients it is not associated with headache. Vestibular migraine is characterized by an extremely varied manifestation; its attacks last from seconds to days; it can occur at any time in life; and its diagnosis is difficult, especially since it must be differentiated from Meniere's disease, vestibular paroxysmia, and transient ischemic attacks. During the attack pathological spontaneous or positional nystagmus and postural imbalance are found in 70–90%; during the attack-free interval less severe ocular motor signs are found in about 60%. This review delineates the clinical features of vestibular migraine and distinguishes it from motion sickness-like symptoms and nonvestibular dizziness in migraine. Finally, the case is made for including the term ‘vestibular migraine’ in the International Headache Classification as a subcategory of migraine which is distinct from ‘basilar-type migraine’ and ‘benign paroxysmal vertigo of childhood.’ ","PeriodicalId":100600,"journal":{"name":"Headache Currents","volume":"3 1","pages":"12-19"},"PeriodicalIF":0.0,"publicationDate":"2006-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1743-5013.2006.00027.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84412761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 40

Migraine and Vertigo: Genetics and Mechanisms—Scientific Abstracts and Commentary 偏头痛和眩晕:遗传学和机制-科学摘要和评论

Headache Currents Pub Date : 2006-03-28 DOI: 10.1111/j.1743-5013.2006.00026.x

Joanna C. Jen M.D., Ph.D.

引用次数: 0

Migraine and Vertigo: Classification and Clinical Features 偏头痛和眩晕:分类和临床特征

Headache Currents Pub Date : 2006-03-28 DOI: 10.1111/j.1743-5013.2006.00028.x

Marianne Dieterich M.D.

引用次数: 0

The Neural Matrix of Pain Processing and Placebo Analgesia: Evidence from Functional Imaging 疼痛加工和安慰剂镇痛的神经基质:来自功能成像的证据

Headache Currents Pub Date : 2005-12-06 DOI: 10.1111/j.1743-5013.2005.00022.x

Irene Tracey Ph.D.