Chemosensors最新文献

{"title":"Evaluation of the Essential Oil Composition of Five Thymus Species Native to Greece","authors":"Eleni Kakouri, D. Daferera, Anastasia Andriopoulou, P. Trigas, P. Tarantilis","doi":"10.3390/chemosensors12010007","DOIUrl":"https://doi.org/10.3390/chemosensors12010007","url":null,"abstract":"The genus Thymus encompasses a wide array of taxa, many of which remain underexplored in terms of their phytochemical profile. In this study, we investigated the phytochemical composition of volatile compounds of five Thymus species native to Greece using gas chromatography combined with mass spectrometry. Two samples of T. parnassicus collected from Mts Parnitha and Parnassos were studied. The predominant compounds in the Parnitha sample were α-cadinol (13.53%), E-caryophyllene (11.83%) and selin-11-en-4α-ol (7.29%). The sample from Mt. Parnassos exhibited a high concentration of E-caryophyllene (35.20%) followed by β-bisabolene (10.41%). Additionally, two species, namely T. leucotrichus subsp. leucotrichus and T. atticus, were collected on Mt. Chelmos (Peloponnese). The essential oil of T. leucotrichus was rich in elemol (35.56%), α-eudesmol (11.15%) and β-eudesmol (6.11%). Thymus atticus exhibited a high concentration in linalool (63.04%) and p-cymene (25.63%). In addition, two samples of T. holosericeus collected from Kefalonia Ιsland were both rich in geraniol (89.9% and 87.7%, respectively). We also examined the volatile profile of T. laconicus, a local endemic species of SE Peloponnese (Lakonia area), which remains unexplored. Carvacrol (32.7%) and p-cymene (29.7%) were identified as the dominant compounds. Our study contributes valuable insights into the chemical profile of Thymus spp. and sheds further light on the well-known chemical polymorphism within this genus.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"36 23","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139131459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Sensitive and Selective MEMS Gas Sensor Based on WO3/Al2O3/Graphite for 2-Chloroethyl Ethyl Sulfide (2-CEES) Detection","authors":"Liang Yang, Wangze Cheng, Wenlong Yan, Li Wen, Changyue Xia, Chuang Sun, Doumeng Hu, Yunong Zhao, Xiaohui Guo, Wei Zeng, Siliang Wang","doi":"10.3390/chemosensors12010005","DOIUrl":"https://doi.org/10.3390/chemosensors12010005","url":null,"abstract":"The detection and monitoring of toxic and harmful gases play a vital role in environmental protection, human health, and industrial and agricultural production. However, it is still challenging to develop gas sensors for the detection of toxic and harmful gases with high sensitivity, good recovery and excellent selectivity. In this study, WO3/Al2O3/graphite composite materials were used for an MEMS 2-CEES gas sensor (dichlorodiethyl sulfide simulation), and the corresponding sensing properties were explored. The experimental results show that when the working temperature is 340 °C, the response of the sensor to 2-CEES gas with a concentration of 5.70 ppm is 69%, the response time is 5 s and the recovery time is 42 s. The sensor also has the advantages of long-term stability and high selectivity. Furthermore, the MEMS gas sensor array based on WO3/Al2O3/graphite composite materials has been achieved and also exhibits excellent sensing performance. Overall, this study provides a strategy for realizing high-performance dichlorodiethyl sulfide gas sensors.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":" 2","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139140363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Label-Free Electrochemical Sensing Using Glassy Carbon Electrodes Modified with Multiwalled-Carbon Nanotubes Non-Covalently Functionalized with Human Immunoglobulin G","authors":"M. L. Mujica, Alejandro Tamborelli, Pablo Dalmasso, Gustavo Rivas","doi":"10.3390/chemosensors12010004","DOIUrl":"https://doi.org/10.3390/chemosensors12010004","url":null,"abstract":"This work reports new analytical applications of glassy carbon electrodes (GCE) modified with a nanohybrid obtained by non-covalent functionalization of multi-walled carbon nanotubes (MWCNTs) with human immunoglobulin G (IgG) (GCE/MWCNT-IgG). We report the label-free and non-amplified breast cancer 1 gen (BRCA1) biosensing based on the facilitated adsorption of the DNA probe at the nanohybrid modified GCE and the impedimetric detection of the hybridization event in the presence of the redox marker benzoquinone/hydroquinone. The resulting genosensor made the fast, highly selective, and sensitive quantification of BRCA1 gene possible, with a linear range between 1.0 fM and 10.0 nM, a sensitivity of (3.0 ± 0.1) × 102 Ω M−1 (R2 = 0.9990), a detection limit of 0.3 fM, and excellent discrimination of fully non-complementary and mismatch DNA sequences. The detection of BRCA1 in enriched samples of diluted human blood serum showed a recovery percentage of 94.6%. Another interesting analytical application of MWCNT-IgG-modified GCE based on the catalytic activity of the exfoliated MWCNTs is also reported for the simultaneous quantification of dopamine and uric acid in the presence of ascorbic acid, with detection limits at submicromolar levels for both compounds.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"358 22","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139148928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wavelength-Stable Metal Grating Distributed Feedback Quantum Cascade Laser Emitting at λ ~ 7.2 μm","authors":"Kedi Ma, Zizhuo Liu, Feng-Min Cheng, Pengchang Yang, Hongxiao Li, Shan Niu, Gaohui Ge, Hao Xu, N. Zhuo, Hui Su, Jinchuan Zhang","doi":"10.3390/chemosensors12010002","DOIUrl":"https://doi.org/10.3390/chemosensors12010002","url":null,"abstract":"In this research, we demonstrate a wavelength-stable continuous wave (CW) distributed feedback (DFB) quantum cascade laser (QCL) emitting at 7.2 μm using a surface metal grating approach without epitaxial regrowth. The deep metal grating provides an appropriate DFB coupling coefficient and enhanced thermal extraction, resulting in improved lasing performance and the realization of impressive wavelength stability. Quantitatively, the temperature tuning coefficient of the single-mode emission is only 0.54 nm/°C from 20 °C to 70 °C, and the current tuning coefficient of the single-mode emission is 3.2 nm/A from 1.0 A to 1.6 A. A DFB-QCL with a 2 mm cavity length exhibits a low threshold current of 0.6 A and a power of 1.1 W with a slope efficiency of 1 W/A in the CW mode at 300 K. A single-mode operation with a side mode suppression ratio of 33 dB and a single-lobed far-field without beam steering is obtained in the working temperature range of 20–70 °C The improved wavelength stability using a deep surface metal grating approach promises simplified fabrication, which is meaningful for the commercial applications of QCLs.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"13 28","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139156417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near-Perfect Infrared Transmission Based on Metallic Hole and Disk Coupling Array for Mid-Infrared Refractive Index Sensing","authors":"Lingyi Xu, Jianjun Lai, Qinghua Meng, Changhong Chen, Yihua Gao","doi":"10.3390/chemosensors12010003","DOIUrl":"https://doi.org/10.3390/chemosensors12010003","url":null,"abstract":"Nanostructured color filters, particularly those generated by the extraordinary optical transmission (EOT) resonance of metal–dielectric nanostructures, have been intensively studied over the past few decades. In this work, we propose a hybrid array composed of a hole array and a disk array with the same working period within the 3–14 μm mid-infrared band. Through numerical simulations, near-perfect transmission (more than 99%) and a narrower linewidth at some resonance wavelengths were achieved, which is vital for highly sensitive sensing applications. This superior performance is attributed to the surface plasmon coupling resonance between the hole and disk arrays. A high tunability of the near-perfect transmission peak with varying structural parameters, characteristics of sensitivity to the background refractive index, and angle independence were observed. We expect that this metallic hole and disk coupling array is promising for use in various applications, such as in plasmon biosensors for the high-sensitivity detection of biochemical substances.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"12 12","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139155327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near Infrared and UV-Visible Spectroscopy Coupled with Chemometrics for the Characterization of Flours from Different Starch Origins","authors":"Samuele Pellacani, Marco Borsari, M. Cocchi, A. D’Alessandro, C. Durante, Giulia Farioli, L. Strani","doi":"10.3390/chemosensors12010001","DOIUrl":"https://doi.org/10.3390/chemosensors12010001","url":null,"abstract":"This work tested near-infrared (NIR) and UV-visible (UV-Vis) spectroscopy coupled with chemometrics to characterize flours from different starch origins. In particular, eighteen starch-containing flours (e.g., type 00 flour, rye, barley, soybean, chestnut, potato, spelt, buckwheat, oat, millet, rice, durum wheat, amaranth, chickpea, sesame, corn, hemp and sunflower flours) were analyzed with a twofold objective: chemically characterizing the investigated flours and laying the groundwork for the development of a fast and suitable method that can identify the botanical source of starch in food. This could ensure ingredient traceability and aid in preventing/detecting food fraud. Untargeted approaches were used for this study, involving the simultaneous acquisition of a large amount of chemical information (UV-Vis on extracted starch and NIR signals on raw flours) coupled with chemometric techniques. UV-VIS spectra were acquired between 225 and 800 nm after sample pretreatment to extract starch. NIR spectra were acquired between 900 and 1700 nm using a poliSPEC NIRe portable instrument on the flours without any kind of pretreatments. An initial exploratory investigation was conducted using principal component analysis and cluster analysis, obtaining interesting preliminary information on patterns among the investigated flours. In particular, the UV-Vis model successfully discerned samples such as potato, chestnut, sunflower, durum wheat, sesame, buckwheat, rice, corn, spelt and 00-type flours. PCA model results obtained from the analysis of NIR spectra also provided comparable results with the UV-Vis model, particularly highlighting the differences observed between hemp and potato flours with soybean flour. Some similarities were identified between other flours, such as barley and millet, rye and oats, and chickpea and amaranth. Therefore, some flour samples underwent surface analysis via scanning electron microscope (SEM) using the Nova NanoSEM 450 to detect distinctive morphology.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"32 2","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138947607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectroscopy, a Tool for the Non-Destructive Sensory Analysis of Plant-Based Foods and Beverages: A Comprehensive Review","authors":"T. Basile, D. Mallardi, M. Cardone","doi":"10.3390/chemosensors11120579","DOIUrl":"https://doi.org/10.3390/chemosensors11120579","url":null,"abstract":"In recent years, there has been a significant rise in the popularity of plant-based products due to various reasons, such as ethical concerns, environmental sustainability, and health benefits. Sensory analysis is a powerful tool for evaluating the human appreciation of food and drink products. To link the sensory evaluation to the chemical and textural compositions, further quantitative analyses are required. Unfortunately, due to the destructive nature of sensory analysis techniques, quantitative evaluation can only be performed on samples that are different from those ingested. The quantitative knowledge of the analytical parameters of the exact sample ingested would be far more informative. Coupling non-destructive techniques, such as near-infrared (NIR) and hyperspectral imaging (HSI) spectroscopy, to sensory evaluation presents several advantages. The intact sample can be analyzed before ingestion, providing in a short amount of time matrices of quantitative data of several parameters at once. In this review, NIR and imaging-based techniques coupled with chemometrics based on artificial intelligence and machine learning for sensory evaluation are documented. To date, no review article covering the application of these non-destructive techniques to sensory analysis following a reproducible protocol has been published. This paper provides an objective and comprehensive overview of the current applications of spectroscopic and sensory analyses based on the state-of-the-art literature from 2000 to 2023.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"271 ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid and Sensitive On-Site Detection of Fipronil in Foods Using Evanescent Wave Fluorescent Immunosensor","authors":"Yujing Li, Wenjuan Xu, Jingjing Liu, E. Zhang, Hejie Li, Yan Zhang, Jing Zhang, Chunsheng Li, Xiaoguang Zhang","doi":"10.3390/chemosensors11120578","DOIUrl":"https://doi.org/10.3390/chemosensors11120578","url":null,"abstract":"Fipronil (FIP), a broad-spectrum phenylpyrazole insecticide, is highly toxic and threatens human health and ecological balance. Developing convenient, rapid, portable analytical technology for on-site and high-frequency testing of FIP is essential to reduce its damage. Herein, a monoclonal antibody (Clone F-3F6) against FIP, with high affinity and specificity, was produced using a novel immunogen, FIP-BSA, which was simply and directly synthesized by conjugating FIP with bovine serum albumin (BSA). Among the previously reported antibodies, F-3F6 acts more specifically against FIP. The FIP metabolites fipronil desulfinyl, fipronil sulfide, and fipronil sulfone showed lower cross-reactivity, and other pesticides were not recognized. To achieve high-frequency and on-site measurements of FIP, an evanescent wave fluorescence biosensor was built by integrating evanescent wave fluorescence technology, a functionalized fiber bioprobe, and a fluorescence-labeled F-3F6 antibody. The detection limit of FIP was 0.032 μg/L. The detection results of real milk and water samples showed that all the coefficients of variation were less than 10%, and the recovery ranged from 90 to 120%. The high reusability and stability of functionalized fiber bioprobe enables the accurate, cost-effective, high-frequency, and facile quantitative detection of FIP. This highly specific and reliable evanescent wave fluorescence biosensor will be well suited to the sensitive and high-frequency on-site analysis of only FIP in food.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"12 12","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138966162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Speciation of Iron Using Desferal via Simple pH Change and a Single Calibration Curve: High-Throughput Optical Sensor Based on 96-Well Plates and an Overhead Book Scanner as Detector","authors":"Dimitrios Baltzis, Apostolia Tsiasioti, C. Zacharis, P. Tzanavaras","doi":"10.3390/chemosensors11120577","DOIUrl":"https://doi.org/10.3390/chemosensors11120577","url":null,"abstract":"In the present study we report the development of an advantageous optical sensor for the speciation of Fe(III)/Fe(II). The sensor is based on the selective reaction of Fe(III) with a Desferal (Deferoxamine) reagent at pH = 2, while both Fe(III) and Fe(II) react with the reagent at pH = 5 using an acetate/glycine buffer. In this way, frequently used extra oxidation (H2O2) or reduction (ascorbic acid or hydroxylamine) steps are avoided. Both species can be determined in the range of 25 to 150 μM using a 96-well plate platform and the instrument-free detection of the colored complex with an overhead book scanner. The LOD is 4 μM, and an additional advantage is that a single calibration curve can be utilized for quantitation. The applicability of the sensor was demonstrated by analyzing commercially available pharmaceutical formulations for quality control purposes.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"17 2","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139002529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioengineered Flagellin–TiO2 Nanoparticle-Based Modified Glassy Carbon Electrodes as a Highly Selective Platform for the Determination of Diclofenac Sodium","authors":"Juan Santiago Hidalgo, É. Tóth, H. Jankovics, C. I. Fort, G. Turdean, Etelka Tombácz, I. Galambos","doi":"10.3390/chemosensors11120576","DOIUrl":"https://doi.org/10.3390/chemosensors11120576","url":null,"abstract":"This study describes the incorporation of bioengineered flagellin (4HIS) protein in conjunction with TiO2 anatase nanoparticles into a chitosan (Chit) polymeric matrix as a highly sensitive electrode modifier for the determination of diclofenac sodium (DS) in wastewater. Two types of electrodes were prepared using a simple drop-casting method. The inner structure of the obtained modified electrode was characterized by scanning electron microscopy (SEM) in combination with energy-dispersive X-ray spectroscopy and isothermal titration calorimetry (ITC). The electrochemical and electroanalytical parameters of DS oxidation at the nanostructured interface of the modified electrode were obtained via cyclic voltammetry and square-wave voltammetry. The analytical parameters for diclofenac electro-detection showed a 50% decrease in LOD and LOQ at Chit + TiO2 + 4HIS/GCE-modified electrode compared with the Chit + 4HIS/GCE-modified electrode. The obtained tools were successfully used for DS detection in drug tablets and wastewater samples. Thus, it was demonstrated that in the presence of a histidine-containing flagellin variant, the electrode has DS recognition capacity which increases in the presence of TiO2 nanoparticles, and both induce excellent performances of the prepared tools, either in synthetic solution or in real samples.","PeriodicalId":10057,"journal":{"name":"Chemosensors","volume":"35 3","pages":""},"PeriodicalIF":4.2,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138594112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}