Genomic Medicine, Biomarkers, and Health Sciences最新文献_第5页

Malignant thymoma: Long-term outcomes with radiotherapy 恶性胸腺瘤:放疗的长期结果

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-09-01 DOI: 10.1016/j.gmbhs.2012.02.001

Ming-Yii Huang , Chih-Jen Huang , Jen-Yang Tang , Chun-Ming Huang , Sheau-Fang Yang , Shah-Hwa Chou

引用次数: 0

Intestinal parasitic infections in human-immunodeficiency-virus-infected persons on highly active antiretroviral therapy in Benin City, Nigeria 尼日利亚贝宁市，接受高效抗逆转录病毒治疗的人类免疫缺陷病毒感染者的肠道寄生虫感染

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-09-01 DOI: 10.1016/j.gmbhs.2011.12.001

Frederick Olusegun Akinbo , Richard Omoregie

{"title":"Intestinal parasitic infections in human-immunodeficiency-virus-infected persons on highly active antiretroviral therapy in Benin City, Nigeria","authors":"Frederick Olusegun Akinbo , Richard Omoregie","doi":"10.1016/j.gmbhs.2011.12.001","DOIUrl":"10.1016/j.gmbhs.2011.12.001","url":null,"abstract":"<div><p>Intestinal parasitic infections have been reported in persons with human immunodeficiency virus (HIV)/AIDS. This study aimed to determine the prevalence of intestinal parasitic infections in HIV-infected patients on highly active antiretroviral therapy (HAART) in Benin City, Nigeria. A total of 285 (84 male and 201 female) HIV-infected adults in the course of HAART were enrolled. Blood and stool specimens were collected from each participant and processed using standard procedures. CD4 count < 200cells/μL and diarrhea were significant risk factors for acquiring intestinal parasitic infections in HIV-positive patients.Anemia was significantly associated with intestinal parasitic infections. <em>Ascaris lumbricoides</em>, hookworm and <em>Strongyloides stercoralis</em> were the only intestinal parasites recovered. We showed a low prevalence (5.3%) of intestinal parasitic infections among HAART patients. Opportunistic coccidia were not detected in this study. Routine diagnosis of intestinal parasites among HIV-infected patients on HAART is advocated.</p></div>","PeriodicalId":100577,"journal":{"name":"Genomic Medicine, Biomarkers, and Health Sciences","volume":"3 3","pages":"Pages 119-122"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmbhs.2011.12.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72881169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

A huge retroperitoneal solitary fibrous tumor 巨大的腹膜后孤立性纤维性肿瘤

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-06-01 DOI: 10.1016/j.gmbhs.2011.08.005

Li-Chun Kao , Wan-Ting Huang , Hsiang-Lin Tsai , Yu-Chung Su , Jeng-Yih Wu , Jaw-Yuan Wang

引用次数: 0

Human adipose-derived stem cells: Isolation, characterization and current application in regeneration medicine 人脂肪源性干细胞:分离、表征及其在再生医学中的应用

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-06-01 DOI: 10.1016/j.gmbhs.2011.08.003

Kuang-Hung Cheng , Tzu-Lei Kuo , Kung-Kai Kuo , Chang-Chun Hsiao

引用次数: 50

Multicentric gastrointestinal stromal tumor of the stomach with wild-type KIT and PDGFRA 应用野生型KIT和PDGFRA检测胃多中心胃肠道间质瘤

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-06-01 DOI: 10.1016/j.gmbhs.2011.08.004

Tzu-Chieh Yin , Sheau-Fang Yang , Jaw-Yuan Wang

引用次数: 0

A study of psychosocial problems in families with HIV-infected children in coastal Karnataka 卡纳塔克邦沿海地区感染艾滋病毒儿童家庭的社会心理问题研究

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-06-01 DOI: 10.1016/j.gmbhs.2011.08.001

Kadke Shreedhara Avabratha , Bhagyalakshmi Kodavanji , Jeena Vaid

{"title":"A study of psychosocial problems in families with HIV-infected children in coastal Karnataka","authors":"Kadke Shreedhara Avabratha , Bhagyalakshmi Kodavanji , Jeena Vaid","doi":"10.1016/j.gmbhs.2011.08.001","DOIUrl":"10.1016/j.gmbhs.2011.08.001","url":null,"abstract":"<div><p>Individuals infected with HIV and AIDS and their families have to cope with a multitude of stressors. These chronic and stigmatized conditions can affect the overall functioning and lifestyle of affected children and their families. The aim of this study was to assess the impact of a child’s illness on psychosocial issues for parents or caregivers and the problems they face. The descriptive study was carried out at Kasturba Medical College Hospital, Mangalore, India. In total, 27 parents or relatives of HIV-positive children were interviewed after obtaining consent. The male/female ratio of affected children was 0.9:1 and the majority of the children were >5 years of age. Ten children were looked after by both parents, 13 by one parent and four by relatives. The majority of the families had a <em>per capita</em> income of <Rs500 per month and a low education level. Of the three children who knew about their illness, two showed behavioral changes. HIV status was known in school for 12 of the 20 school-going children, and discrimination was observed in one case. Family members were supportive in 65% of cases and opposition and fear were the reactions in 30%. Healthcare providers were unsupportive in two cases. Monthly medical expenditure varied from Rs250 to Rs1500. Fifteen children were on antiretroviral therapy largely funded by voluntary organizations. Ninety two percent of the caregivers were aware of the modes of transmission, 85% of the preventive measures and 70% of the complications of HIV/AIDS. In conclusion, in spite of all the efforts raise awareness of HIV, social discrimination and stigmatization persist. General improvements in socioeconomic status and levels of knowledge and well-organized health programs will go a long way in the battle against HIV/AIDS.</p></div>","PeriodicalId":100577,"journal":{"name":"Genomic Medicine, Biomarkers, and Health Sciences","volume":"3 2","pages":"Pages 72-75"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmbhs.2011.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86546776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Morphological effects of chronic efavirenz administration on the kidney of adult Wistar rats 慢性给予依非韦伦对成年Wistar大鼠肾脏形态学的影响

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-06-01 DOI: 10.1016/j.gmbhs.2011.08.002

Josiah Obaghwarhievwo Adjene, Isaac Oluwafemi Ajakaye, Precious Osatohanmwen Nosakhare

{"title":"Morphological effects of chronic efavirenz administration on the kidney of adult Wistar rats","authors":"Josiah Obaghwarhievwo Adjene, Isaac Oluwafemi Ajakaye, Precious Osatohanmwen Nosakhare","doi":"10.1016/j.gmbhs.2011.08.002","DOIUrl":"10.1016/j.gmbhs.2011.08.002","url":null,"abstract":"<div><p>Efavirenz is commonly used as part of the highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1. The effects of chronic administration of efavirenz on the kidney of adult Wistar rats were investigated. The rats were divided into two groups, those given efavirenz (treatment) and those given water (control), both for 30 days. The animals were sacrificed by cervical dislocation on Day 31 of the experiment and kidneys were dissected, weighed and quickly fixed in 10% formalin for histological analysis. The findings indicate that there was a significant (<em>p</em> < 0.05) decrease in weight and increase in relative weight of treated right and left kidneys compared to the control group. Kidneys in the treated group showed disruption of the cytoarchitecture of the renal cortical structure, diffuse glomerulonephritis with some cell congestion, and dilation of Bowman’s space compared to the control group. Chronic efavirenz administration may therefore have an adverse effect on the kidney function of adult Wistar rats. Further studies to corroborate these observations should be carried out.</p></div>","PeriodicalId":100577,"journal":{"name":"Genomic Medicine, Biomarkers, and Health Sciences","volume":"3 2","pages":"Pages 76-80"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmbhs.2011.08.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86404996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A study on women’s perceptions regarding the requirements and satisfaction of a hospital environment 关于妇女对医院环境的要求和满意度的看法的研究

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-06-01 DOI: 10.1016/j.gmbhs.2011.09.001

Hsien Cheng Lin

{"title":"A study on women’s perceptions regarding the requirements and satisfaction of a hospital environment","authors":"Hsien Cheng Lin","doi":"10.1016/j.gmbhs.2011.09.001","DOIUrl":"10.1016/j.gmbhs.2011.09.001","url":null,"abstract":"<div><p>Practicing gender-based equal rights is an international trend today. An empirical study was conducted to analyze the individual traits of women and their needs in order to determine how female-friendly hospital environments were by focusing on environments fitted for individuals. A structured questionnaire was distributed to the female users of a model female-friendly hospital recognized by the Health Bureau; 200 questionnaires were issued and 154 replies were valid. Variance and multiple regression analyses were conducted on the valid questionnaires. The results of the study indicate that: (1) the hospital’s efforts to promote a female-friendly hospital environment fell below women’s expectations; (2) when the hospital offered a less female-friendly hospital environment, female patients were less satisfied; and (3) “educational attainment” and “experience of a female-friendly hospital environment” most significantly influence the degree to which female patients would be satisfied with services provided by hospitals. We recommend hospitals educate medical staff and administrators regarding the concept of gender-based equal rights through relevant training in order to cultivate a high level of awareness and enthusiasm for offering female patients more comprehensive services so that they feel respected when receiving medical treatment.</p></div>","PeriodicalId":100577,"journal":{"name":"Genomic Medicine, Biomarkers, and Health Sciences","volume":"3 2","pages":"Pages 63-71"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmbhs.2011.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79937175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Molecular Detection of Circulating Tumor Cells With Multiple mRNA Markers by Genechip for Colorectal Cancer Early Diagnosis and Prognosis Prediction 用基因芯片检测循环肿瘤细胞多mRNA标记物在大肠癌早期诊断和预后预测中的应用

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-03-01 DOI: 10.1016/S2211-4254(11)60003-4

Shiu-Ru Lin , Ming-Yii Huang , Hui-Jen Chang

引用次数: 1

Female Reproductive Tract Infections Among Vaginal Contraceptive Users in Benin City, Nigeria 尼日利亚贝宁市阴道避孕药使用者中的女性生殖道感染

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2011-03-01 DOI: 10.1016/S2211-4254(11)60007-1

Christopher Aye Egbe , Uchenna Chukwunweike Onwufor , Richard Omoregie , Onaiwu Idahosa Enabulele

{"title":"Female Reproductive Tract Infections Among Vaginal Contraceptive Users in Benin City, Nigeria","authors":"Christopher Aye Egbe , Uchenna Chukwunweike Onwufor , Richard Omoregie , Onaiwu Idahosa Enabulele","doi":"10.1016/S2211-4254(11)60007-1","DOIUrl":"10.1016/S2211-4254(11)60007-1","url":null,"abstract":"<div><p>Female vaginal contraceptives are associated with increased susceptibility to infections. The prevalence of female reproductive tract infections (RTI) among contraceptive users was determined. A total of 187 female participants including 156 contraceptive users and 31 age-matched noncontraceptive users with signs and symptoms of RTIs were recruited for this study. A questionnaire was used to collect demographic information. High vaginal swabs were collected from each participant and processed using standard technique. Female contraceptive users (40.4%) had an increased risk for developing RTIs compared to noncontraceptive users (19.35%) (OR = 2.833, 95 CI = 1.095, 7.276; <em>p</em>= 0.044). Intrauterine device (IUD) users (53.07%; <em>p</em>= 0.032), users of contraceptives for less than 1 year (60.00%; <em>p</em>= 0.003) and age group of 26-30 years (68.18%; <em>p</em>= 0.0001) had significantly higher prevalence of RTIs among contraceptive users. Candida albicans was the most prevalent etiologic agent of RTIs among contraceptive users irrespective of types of contraceptives, bacteria vaginosis caused by other bacterial isolates was the most common RTIs among noncontraceptive users. In this situation, Klebsiella species was found only among IUD users. The study reveals an overall prevalence of 36.90% of female RTIs. Contraceptive users had 1-7 fold increase in developing RTIs. Vaginal candidiasis and bacterial vaginosis were the most common female RTIs observed among contraceptives and noncontraceptive users. Some valuable measures to reduce infections associated with contraceptive use are advocated.</p></div>","PeriodicalId":100577,"journal":{"name":"Genomic Medicine, Biomarkers, and Health Sciences","volume":"3 1","pages":"Pages 49-52"},"PeriodicalIF":0.0,"publicationDate":"2011-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2211-4254(11)60007-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83457111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10