Food Safety and Health最新文献

筛选
英文 中文
A multifaceted review on aureusidin in planta distribution, (bio)synthesis, and bioactivities aureusidin在植物分布、(生物)合成和生物活性方面的多方面综述
Food Safety and Health Pub Date : 2023-10-19 DOI: 10.1002/fsh3.12023
Wenqi Huang, Shiye Lin, Mohamed Farag, Jianbo Xiao
{"title":"A multifaceted review on aureusidin in planta distribution, (bio)synthesis, and bioactivities","authors":"Wenqi Huang,&nbsp;Shiye Lin,&nbsp;Mohamed Farag,&nbsp;Jianbo Xiao","doi":"10.1002/fsh3.12023","DOIUrl":"https://doi.org/10.1002/fsh3.12023","url":null,"abstract":"<p>Aureusidin, a derivative of aurone, imparts a vibrant yellow hue to numerous yellow-rich plants, such as sunflowers and snapdragons. The bright yellow color provides an excellent pigment of choice for plant breeders to cultivate different-colored hybrid species. The biosynthesis of aureusidin relies on a key aureusidin synthase enzyme, which belongs to the plant polyphenol oxidase family. The revelation of its DNA sequence, coupled with transgenic technology, has opened up possibilities for producing exceptionally stunning flower plants. Moreover, aureusidin exhibits remarkable bioactivities in vitro, including anti-microbial, anti-viral, anti-cancer, anti-inflammatory, anti-oxidant, anti-diabetic, anti-hypercholesterolemic, anti-hyperuricemia, histone deacetylase inhibitory, and neuropharmacological properties. However, the majority of studies have focused on in vitro experiments, rather than in vivo disease models, toxicological assessments, and human clinical trials. This review provides a comprehensive overview of all research advancements pertaining to aureusidin highlighting future perspectives to maximize its value, hereby contributing to the application of medicine, agricultural, and biotechnology fields. More studies are needed in the future to assess its toxicology, safety, and biotransformation for potential incorporation in future nutraceuticals.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 2","pages":"170-183"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68180470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent trends in metal-organic frameworks mediated lipase immobilization: A state-of-the-art review 金属有机框架介导的脂肪酶固定化研究进展
Food Safety and Health Pub Date : 2023-09-20 DOI: 10.1002/fsh3.12021
Prasanna J. Patil, Xiaoxiao Dong, Muhammad Usman, Nandini R. Bhambore, Haroon Shah, Chengnan Zhang, Xiuting Li
{"title":"Recent trends in metal-organic frameworks mediated lipase immobilization: A state-of-the-art review","authors":"Prasanna J. Patil,&nbsp;Xiaoxiao Dong,&nbsp;Muhammad Usman,&nbsp;Nandini R. Bhambore,&nbsp;Haroon Shah,&nbsp;Chengnan Zhang,&nbsp;Xiuting Li","doi":"10.1002/fsh3.12021","DOIUrl":"https://doi.org/10.1002/fsh3.12021","url":null,"abstract":"<p>Immobilized lipase is a powerful biocatalytic system with numerous applications in industries, particularly in the energy, pharmaceutical, cosmetic, and food industries. Reusability, simple recovery, and high chemical and thermal stability make it an attractive alternative to traditional chemical catalysts in industrial applications. Novel methods and support materials for immobilizing lipases have recently attracted much attention. Metal-organic frameworks (MOFs) are a promising class of materials for enzyme immobilization carriers due to their appealing features, including a high specific surface area, high specific porosity, a stable framework structure, and a wide variety of functional sites. Due to the protection provided to enzymes by MOFs, several reported MOFs-lipase composites display exceptional catalytic characteristics relative to free lipases. This includes increased enzyme efficiency, stability, selectivity, and recyclability. Herein, we summarize an updated review of the most recent advances in MOFs immobilizing lipases. This review sheds light on the numerous aspects of lipase-MOF immobilization, with special emphasis on different techniques of designing lipase-MOF platforms and the advantages of lipase-MOF composites. Subsequently, molecular simulation approaches in lipase-MOF immobilization are briefly introduced. Moreover, practical applications of MOFs-lipase composites have been outlined. Finally, potential limitations and future directions for MOFs-lipase immobilization research are highlighted.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 2","pages":"139-169"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68180653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possible metabolic effect of acrylamide on biological system 丙烯酰胺对生物系统可能的代谢作用
Food Safety and Health Pub Date : 2023-09-12 DOI: 10.1002/fsh3.12020
Divya Gupta, Shubham Singh, Richa Soni, Shamli S. Gupte, Arti Rathour, Sadhana Shrivastava, Sangeeta Shukla
{"title":"Possible metabolic effect of acrylamide on biological system","authors":"Divya Gupta,&nbsp;Shubham Singh,&nbsp;Richa Soni,&nbsp;Shamli S. Gupte,&nbsp;Arti Rathour,&nbsp;Sadhana Shrivastava,&nbsp;Sangeeta Shukla","doi":"10.1002/fsh3.12020","DOIUrl":"https://doi.org/10.1002/fsh3.12020","url":null,"abstract":"<p>Acrylamide (AA) is a chemical agent mostly used in the manufacture of polymers and copolymers. Recently, it has gained attention because of its production in food items prepared at high-temperature (&gt;120°C) processes, such as frying, toasting, cooking, roasting or baking of high carbohydrate food items. As per the higher exposure of AA, appropriate identification of its toxic effect is necessary. Hepatotoxicity, nephrotoxicity, neurotoxicity, reproductive toxicity, and immunotoxicity of AA have been observed in several studies. AA could also be considered as endocrine-disrupting chemicals and its exposure leads to many hormonal abnormalities. Nearly one in every four couples of a developing nation suffers from infertility, and AA exposure may be one of the reasons. AA is proven as a potent reproductive toxicant, affecting both male and female reproductive organ functioning. This review summarizes research conducted on the toxicity of AA in various organs.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 2","pages":"126-138"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68179293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Introducing degummed water-extracted wild almond oil as a safe vegetable oil through the quality evaluation of par-fried potato sticks and oil thermo-oxidative stability during a continuous prolonged deep-fat frying process 通过对油炸土豆棒的质量评价和油脂在长时间油炸过程中的热氧化稳定性,介绍脱胶水提取野生杏仁油作为一种安全的植物油
Food Safety and Health Pub Date : 2023-09-10 DOI: 10.1002/fsh3.12019
Niloufar Nekouei, Karamatollah Rezaei
{"title":"Introducing degummed water-extracted wild almond oil as a safe vegetable oil through the quality evaluation of par-fried potato sticks and oil thermo-oxidative stability during a continuous prolonged deep-fat frying process","authors":"Niloufar Nekouei,&nbsp;Karamatollah Rezaei","doi":"10.1002/fsh3.12019","DOIUrl":"https://doi.org/10.1002/fsh3.12019","url":null,"abstract":"<p>The purpose of this study is to evaluate the safety of degummed water-extracted wild almond oil as a frying medium. Changes in the physicochemical properties of the oil as well as those of the fried potato sticks were evaluated over 10 h of frying at 180°C. Compared to a reference commercial frying oil, free fatty acid content, smoke point, anisidine value, conjugated dienes concentration, total polar compounds, color index, and viscosity did not change significantly during the frying process. French fries prepared during the 10 h of frying in the wild almond oil indicated lower fat levels than those prepared in the commercial frying oil. This can contribute to the well-being of the consumers as well as to the cost-efficiency of the process. The color indices are additional quality measures for the fried products that were similar for potatoes fried in both oil sources indicating the safe application of water-extracted wild almond oil for frying purposes. The application of water-extracted wild almond oil for frying purposes is found to be a safe process to consider in future frying applications.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 2","pages":"202-213"},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68179272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The estrogen receptor modulatory activity and neuroprotective activity of novel prenylated flavonoids and their structure–activity relationship 新型异戊二烯基黄酮的雌激素受体调节活性和神经保护活性及其构效关系
Food Safety and Health Pub Date : 2023-08-27 DOI: 10.1002/fsh3.12018
Lingrong Wen, Yunfei Yuan, Yueming Jiang, Binghong Xiong, Bao Yang
{"title":"The estrogen receptor modulatory activity and neuroprotective activity of novel prenylated flavonoids and their structure–activity relationship","authors":"Lingrong Wen,&nbsp;Yunfei Yuan,&nbsp;Yueming Jiang,&nbsp;Binghong Xiong,&nbsp;Bao Yang","doi":"10.1002/fsh3.12018","DOIUrl":"https://doi.org/10.1002/fsh3.12018","url":null,"abstract":"<p>Prenylated flavonoids are promising nutraceuticals with diverse bioactivities. However, publications on the mechanism of action and structure–activity relationship of prenylated flavonoids are limited. In the present work, six novel prenylated flavonoids (C8–C13) with diversity structure were prepared. Their estrogen receptor (ER) modulator activity and neuroprotective activity were investigated by cell assays. C8, C9, and C10 with 8-C-prenyl and 7-OH showed agonistic activities toward ERα and ERβ, along with high ERβ selectivity. However, C11 and C12 were ERα-selective agonists. The position and substituent moiety of prenylation, C-ring configuration, and flavonoid skeleton were important for the ER modulating activities. Hydrogen bonds between 3′-OH and Leu339 in ERβ, and 5′-OH and Glu305 in ERβ might respond for the higher agonistic activity of C8 and C10, respectively. C8, C9, C11, and C12 showed more potency than 17β-estradiol on neuroprotection in glutamate-treated PC-12 cells. C8 and C12 could reverse reactive oxygen species overproduction and reduction of Δψm induced by glutamate through increase of the expression of <i>ERS1</i>, <i>SOD1</i>, <i>SOD2</i>, <i>CAT</i>, and <i>GPx4</i> and decrease of <i>caspase-3</i> expression, suggesting C8, and C9 might interact with ERα, promote antioxidant defense, mitigate oxidative stress, and improve mitochondrial function to exert the neuroprotection activities.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 2","pages":"184-201"},"PeriodicalIF":0.0,"publicationDate":"2023-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68180726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Raphanus sativus functional potential: Impact of the analytical extraction technique on the bioaccessibility interpretation 萝卜的功能潜力:分析提取技术对生物可及性解释的影响
Food Safety and Health Pub Date : 2023-07-27 DOI: 10.1002/fsh3.12014
Daniela Ramirez, Vanesa Beretta, Carolina Torres-Palazzolo, Alejandra B. Camargo
{"title":"Raphanus sativus functional potential: Impact of the analytical extraction technique on the bioaccessibility interpretation","authors":"Daniela Ramirez,&nbsp;Vanesa Beretta,&nbsp;Carolina Torres-Palazzolo,&nbsp;Alejandra B. Camargo","doi":"10.1002/fsh3.12014","DOIUrl":"https://doi.org/10.1002/fsh3.12014","url":null,"abstract":"<p>Radishes (<i>Raphanus sativus</i> L.) are cruciferous vegetables with remarkable nutraceutical properties given their distinctive isothiocyanates (ITCs) profile. These compounds are formed after glucosinolates-Myrosinase enzymolysis. Although it is important to characterize radishes' ITCs levels, it is also necessary to evaluate the bioactive compounds' physiological fate after radishes ingestion. To do so, the extraction techniques should adapt to such conditions of high aqueous environment. In this work, we studied the bioaccessibility of ITCs and indole-3-carbinol (I3C) in radishes taproots considering the analytical implications of this biological process. Results showed that ITCs and indole profiles in the radish's taproots after aqueous-myrosinase hydrolysis followed by Dispersive Liquid-Liquid Microextraction were distinctively different from other reports. After in vitro digestion, raphasatin showed the highest bioaccessibility despite its low quantitative yields. Notably, I3C and S-Sulforaphene become promising phytochemicals, due to their bioaccessibility and their considerable remaining amounts after digestion.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 1","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50145453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Food safety and health: Advancing knowledge and collaboration for a safer future 食品安全与健康:为更安全的未来推进知识和合作
Food Safety and Health Pub Date : 2023-07-26 DOI: 10.1002/fsh3.12017
Mingqian Tan, Shuo Wang, Maria Daglia, Maojun Jin, A. M. Abd El-Aty
{"title":"Food safety and health: Advancing knowledge and collaboration for a safer future","authors":"Mingqian Tan,&nbsp;Shuo Wang,&nbsp;Maria Daglia,&nbsp;Maojun Jin,&nbsp;A. M. Abd El-Aty","doi":"10.1002/fsh3.12017","DOIUrl":"https://doi.org/10.1002/fsh3.12017","url":null,"abstract":"<p>We are delighted to announce the launch of Food Safety and Health, an innovative scientific journal dedicated to advancing the field of food safety and health. In today's interconnected world, the safety and health of our food supply have become paramount, posing challenges as the population grows and global trade increases (World Health Organization, <span>2020</span>). Recognizing this pressing need, Food Safety and Health takes a comprehensive approach to address the multidimensional aspects of food safety, health, and their interplay (Smith &amp; Johnson, <span>2021</span>).</p><p>Our primary objective is to publish exceptional articles showcasing the latest advancements, superior quality, and contemporary perspectives on food safety and health. With its profound impact on human well-being and progress, research in these crucial areas has garnered substantial attention within the research community. Food Safety and Health provides authors with a convenient and efficient platform to communicate their research findings to the global food science community.</p><p>Food Safety and Health is proudly associated with the esteemed International Association of Dietetic Nutrition and Safety and enjoys valuable cosponsorship from several esteemed institutions, including Dalian Polytechnic University, Dalian Minzu University, Guangdong Ocean University, Ocean University of China, Tianjin University of Science and Technology, Chengdu University, South China Agricultural University, Xihua University, Hebei Agricultural University, Kunming University of Science and Technology, Jimei University, Shaanxi University of Science and Technology, Zhejiang University of Science and Technology, Zhejiang Agriculture and Forestry University, and Suzhou College.</p><p>We take immense pleasure in introducing the distinguished editorial team of Food Safety and Health, consisting of 18 globally renowned researchers and influential experts hailing from 19 countries, including China, Croatia, Ecuador, Egypt, Germany, Greece, Italy, Japan, Portugal, Romania, Saudi Arabia, South Korea, Spain, Turkey, Slovenia, South Africa, Serbia, Sweden, and the USA. This diverse panel of editors brings a wealth of expertise and citation impact to the journal. They are committed to delivering professional reviews and prompt responses from the moment of submission to publication, ensuring a seamless experience for authors. Furthermore, with the support of Wiley Publishing, the papers published in Food Safety and Health will receive exceptional assistance in technical editing, article layout, and promotion, guaranteeing high-quality publication standards.</p><p>Food Safety and Health Journal showcases state-of-the-art original research, communication, critical reviews, minireviews, systematic reviews, commentary, perspective articles, meta-analyses, letters to the editor, and opinion pieces covering a wide range of food safety and health subjects. The journal encompasses various relevant ar","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 1","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50154579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of dietary polyphenols in the control of chronic noncommunicable diseases 膳食多酚在控制慢性非传染性疾病中的作用
Food Safety and Health Pub Date : 2023-07-23 DOI: 10.1002/fsh3.12013
Yasmany Armas Díaz, Maria Soledad Ferreiro Cotorruelo, Maurizio Battino
{"title":"The role of dietary polyphenols in the control of chronic noncommunicable diseases","authors":"Yasmany Armas Díaz,&nbsp;Maria Soledad Ferreiro Cotorruelo,&nbsp;Maurizio Battino","doi":"10.1002/fsh3.12013","DOIUrl":"https://doi.org/10.1002/fsh3.12013","url":null,"abstract":"<p>Noncommunicable chronic diseases (NCDs) are among the leading causes of death and disability worldwide. The most common NCDs are cancer, obesity, cardiovascular diseases, and diabetes. Nowadays, they represent one of the greatest challenges health systems face worldwide. The increase in the consumption of polyphenol-rich foods could contribute to the reduction of these pathologies, due to their antioxidant, anti-inflammatory, anticancer, immunomodulatory, and cardiovascular protective properties, among others. This review aims to highlight some studies carried out in recent years to enhance the possible benefits of a diet rich in polyphenols in the prevention or treatment of NCDs.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 1","pages":"13-21"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50117660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cellular antioxidant activity measurement: An alternative to chemical antioxidant methods? 细胞抗氧化活性测量:化学抗氧化方法的替代方法?
Food Safety and Health Pub Date : 2023-07-23 DOI: 10.1002/fsh3.12012
Daniel Granato
{"title":"Cellular antioxidant activity measurement: An alternative to chemical antioxidant methods?","authors":"Daniel Granato","doi":"10.1002/fsh3.12012","DOIUrl":"https://doi.org/10.1002/fsh3.12012","url":null,"abstract":"<p>Oxidative stress occurs when the production of reactive oxygen species (ROS) overpasses their degradation and buffering by endogenous antioxidants and those derived from the diet (exogenous antioxidants). In food science and nutrition, assessing antioxidant activity relies on chemical reactions—chemical test-tube assays—and human and murine cell lines. Usually, an ROS inductor, such as hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) or peroxyl radicals (ROO<sup>•</sup>), is used to induce oxidation. Some biomarkers related to endogenous protection (i.e., catalase, superoxide dismutase, and glutathione reductase), oxidation-end products (i.e., malondialdehyde), and intracellular ROS generation can be quantitatively determined. Herein, some insights into using human cell lines and related biomarkers are described, and the downsides of using chemical antioxidant assays are explained. In conclusion, research on antioxidants should be based on using relevant human cell cultures. In contrast, chemical antioxidant assays should be limited to an initial screening as their physiological importance is negligible.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 1","pages":"9-12"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50117659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of Staphylococcus aureus and methicillin-resistant S. aureus from yak 牦牛金黄色葡萄球菌和耐甲氧西林金黄色葡萄菌的鉴定
Food Safety and Health Pub Date : 2023-07-20 DOI: 10.1002/fsh3.12011
Yanying Zhao, Qian Huang, Fenglan Bai, Mengyou Luo, Junni Tang
{"title":"Characterization of Staphylococcus aureus and methicillin-resistant S. aureus from yak","authors":"Yanying Zhao,&nbsp;Qian Huang,&nbsp;Fenglan Bai,&nbsp;Mengyou Luo,&nbsp;Junni Tang","doi":"10.1002/fsh3.12011","DOIUrl":"https://doi.org/10.1002/fsh3.12011","url":null,"abstract":"<p><i>Staphylococcus aureus</i>, particularly methicillin-resistant <i>S. aureus</i> (MRSA), is an important zoonotic pathogen which not only causes significant economic loss in livestock production but also emerges as a potential threat to public health. Compared with bovines, the information on the colonization of <i>S. aureus</i> and MRSA in yaks, the only bovine species providing meat and other necessities for Tibetans living at high altitude, is very limited. Therefore, in the current study, <i>S. aureus</i> and MRSA prevalence, virulence genes, and antibiotic and antiseptic resistance properties in yaks from 18 counties of Ganzi Prefecture, Sichuan province, China were investigated. The results revealed that the overall prevalence of <i>S. aureus</i> during yak breeding was 7.10% among 1281 samples (91/1281), containing 9.44% from nasal (62/657) and 4.65% from anus (29/624). Nearly all of the <i>S. aureus</i> isolates carried at least one staphylococcal enterotoxin (SE) gene and the predominant enterotoxin gene was <i>selx</i> (51.65%). In addition, virulence genes (<i>hlα</i>, <i>hlβ</i>, <i>pvl</i>, and <i>tsst-1</i>), antiseptic resistance genes (<i>qacA/B</i>, <i>qacC</i>, and <i>qacG</i>), and heavy metal resistance genes (<i>copA</i>, <i>arsB</i>, <i>cadD</i>, and <i>arsA</i>) were also found. Furthermore, 24 MRSA strains were identified. SCCmec, spa, and multilocus sequence typing typing revealed that the predominant types of MRSA were ST59-IVa-t437 and ST59-III-t437. It was noteworthy that all these methicillin-resistant strains were resistant to two or more antibiotics and possessed virulence genes. The minimal inhibitory concentration (MIC) values of antiseptic peroxyacetic acid, sodium hypochlorite, and benzalkonium bromide against these MRSA strains were measured and the MIC values of benzalkonium bromide (1.22–9.77 μg/mL) were relatively low. Furthermore, the challenge with 1/4 MIC of oxacillin sodium or ofloxacin or benzalkonium bromide for 216 h increased the resistance of the MRSA strain YB786 to these antibiotics but decreased the MIC value of benzalkonium bromide. The results provide an indication of the health risks associated with these <i>S. aureus</i> strains, especially methicillin-resistant strains from yaks and new approaches are needed to treat these strains.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"1 1","pages":"82-92"},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50138720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信