Evidence-based Healthcare最新文献_第7页

Universal screening does not reduce the prevalence of visual impairment in older people 普遍筛查并不能降低老年人视力损害的患病率

Evidence-based Healthcare Pub Date : 2004-06-01 DOI: 10.1016/J.EHBC.2004.03.009

R. Enzenauer

引用次数: 1

Treatment of unilateral visual impairment in preschool children modestly improves visual acuity 学龄前儿童单侧视力障碍的治疗可适度改善视力

Evidence-based Healthcare Pub Date : 2004-06-01 DOI: 10.1016/J.EHBC.2004.03.002

Maria S Castanes

引用次数: 0

Major bleeding episodes occur in people receiving anticoagulant therapy for venous thromboembolism 大出血发作发生在接受抗凝治疗的静脉血栓栓塞患者中

Evidence-based Healthcare Pub Date : 2004-06-01 Epub Date: 2004-04-21 DOI: 10.1016/j.ehbc.2004.03.004

Christoph Pechlaner MD (Commentary Author)

{"title":"Major bleeding episodes occur in people receiving anticoagulant therapy for venous thromboembolism","authors":"Christoph Pechlaner MD (Commentary Author)","doi":"10.1016/j.ehbc.2004.03.004","DOIUrl":"https://doi.org/10.1016/j.ehbc.2004.03.004","url":null,"abstract":"<div><h3>Question</h3><p>What is the clinical impact of bleeding in people taking anticoagulants for venous thromboembolism?</p></div><div><h3>Study design</h3><p>Systematic review with meta-analysis.</p></div><div><h3>Main results</h3><p>Thirty-three studies met inclusion criteria (29 randomised controlled trials, 4 prospective cohort studies; 10,757 people). Major bleeding occurred in <span><math><mtext>276</mtext><mtext>10,757</mtext></math></span> (2.6%) of people receiving anticoagulant therapy for venous thromboembolism (see Table 1). Intracranial bleeding accounted for <span><math><mtext>24</mtext><mtext>276</mtext></math></span> (8.7%) of all major bleeding episodes with fatalities occurring in <span><math><mtext>11</mtext><mtext>24</mtext></math></span> (45.8%) of these episodes.<span><div><div><table><tbody><tr><td><strong>Table 1</strong> Clinical impact of bleeding in people receiving anticoagulant therapy for venous thromboembolism.</td></tr><tr><td></td><td>Absolute risk (%)</td><td>Absolute risk for fatal episodes (%)</td><td>Rate of bleeding per 100 patient-years (95% CI)</td></tr><tr><td>Entire anticoagulation period</td><td></td><td></td><td></td></tr><tr><td>Major bleeding episodes</td><td>276/10,757 (2.6%)</td><td>37/276 (13.4%)</td><td>7.22 (7.19 to 7.24)</td></tr><tr><td>Intracranial bleeding episodes</td><td>24/8717 (0.3%)</td><td>11/24 (45.8%)</td><td>1.15 (1.14 to 1.16)</td></tr></tbody></table></div></div></span></p></div><div><h3>Authors’ conclusions</h3><p>Major bleeding associated with anticoagulant therapy has considerable clinical consequences that will need to be weighed against therapeutic benefits in people with venous thromboembolism.</p></div>","PeriodicalId":100512,"journal":{"name":"Evidence-based Healthcare","volume":"8 3","pages":"Pages 171-173"},"PeriodicalIF":0.0,"publicationDate":"2004-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehbc.2004.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71829102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addition of artesunate to standard antimalarial drugs reduces treatment failure 在标准抗疟药物中加入青蒿琥酯可减少治疗失败

Evidence-based Healthcare Pub Date : 2004-06-01 Epub Date: 2004-04-20 DOI: 10.1016/j.ehbc.2004.03.020

Timothy ME Davis (Commentary Author)

{"title":"Addition of artesunate to standard antimalarial drugs reduces treatment failure","authors":"Timothy ME Davis (Commentary Author)","doi":"10.1016/j.ehbc.2004.03.020","DOIUrl":"https://doi.org/10.1016/j.ehbc.2004.03.020","url":null,"abstract":"<div><h3>Question</h3><p><span>What is the effect of adding artesunate to existing drug regimens for people with acute uncomplicated </span><em>Plasmodium falciparum</em> malaria?</p></div><div><h3>Study design</h3><p>Systematic review with meta-analysis.</p></div><div><h3>Main results</h3><p>16 trials met inclusion criteria. Standard antimalarial drugs in the trials varied (sulfadoxine–pyrimethamine: 7 RCTs; amodiaquine<span><span>: 3 RCTs; chloroquine: 3 RCTs; mefloquine: 3 RCTs). Adding artesunate for 3 days to standard antimalarial drugs significantly reduced 14 and 28 day's failure rates compared with standard drugs alone (15 RCTs; OR for failure by 14 day 0.20, 95% CI 0.17 to 0.25; OR for failure by 28 days 0.23, 95% CI 0.19 to 0.28). Addition of artesunate for 1 day was not as effective as 3 days, but still significantly reduced failure rates compared with standard drugs alone (6 RCTs; OR for failure by 14 days 0.61, 95% CI 0.48 to 0.77; OR for failure by 28 days 0.68, 95% CI 0.53 to 0.89). The </span>incidence of side effects was similar in both groups.</span></p></div><div><h3>Authors’ conclusions</h3><p>Adding artesunate to a standard antimalarial drug regimen for 3 days leads to a consistent decrease in treatment failure at 14 days, irrespective of the standard antimalarial drug used.</p></div>","PeriodicalId":100512,"journal":{"name":"Evidence-based Healthcare","volume":"8 3","pages":"Pages 156-158"},"PeriodicalIF":0.0,"publicationDate":"2004-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehbc.2004.03.020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71829109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Length of hospital stay for elderly people is substantially higher in the NHS compared with Kaiser Permanente and US Medicare programmes 与Kaiser Permanente和美国医疗保险计划相比，NHS中老年人的住院时间要长得多

Evidence-based Healthcare Pub Date : 2004-06-01 Epub Date: 2004-04-22 DOI: 10.1016/j.ehbc.2004.03.016

David P Sklar MD (Commentary Author)

引用次数: 1

Patient satisfaction questionnaires equally acceptable to patients 患者满意度问卷对患者同样可接受

Evidence-based Healthcare Pub Date : 2004-06-01 DOI: 10.1016/J.EHBC.2004.03.007

Stephen J. Aragon, M. C. Edwards

引用次数: 4

Survival of people with out-of-hospital cardiac arrest is not improved by equipping first responders with an automated external defibrillator☆ 院外心脏骤停患者的生存率并没有通过为急救人员配备自动体外除颤器而得到改善

Evidence-based Healthcare Pub Date : 2004-06-01 DOI: 10.1016/J.EHBC.2004.03.012

J. Finn, I. Jacobs

引用次数: 3

Nurse-led intervention increases smoking cessation among people with coronary heart disease $ 护士主导的干预增加了冠心病患者的戒烟率

Evidence-based Healthcare Pub Date : 2004-06-01 DOI: 10.1016/J.EHBC.2004.03.008

David W. Brown

引用次数: 3

High intensity counselling or behavioural interventions can result in moderate weight loss 高强度的咨询或行为干预可导致适度的体重减轻

Evidence-based Healthcare Pub Date : 2004-06-01 DOI: 10.1016/J.EHBC.2004.03.006

E. Slevin

引用次数: 5

Healthcare quality improvement programme improves monitoring of people with diabetes 医疗保健质量改进方案改善了对糖尿病患者的监测

Evidence-based Healthcare Pub Date : 2004-06-01 DOI: 10.1016/J.EHBC.2004.03.005

P. Denig

引用次数: 0