中华妇产科杂志最新文献

{"title":"[Do not injury, please！].","authors":"J H Lang","doi":"10.3760/cma.j.cn112141-20240829-00481","DOIUrl":"https://doi.org/10.3760/cma.j.cn112141-20240829-00481","url":null,"abstract":"","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 2","pages":"81-82"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Challenges and considerations in diagnosis and treatment of cervical insufficiency].","authors":"C Y Shi, H X Yang","doi":"10.3760/cma.j.cn112141-20241119-00612","DOIUrl":"10.3760/cma.j.cn112141-20241119-00612","url":null,"abstract":"","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 2","pages":"94-98"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Chinese expert consensus on the role of hysteroscopic morphological characteristics in the fertility preservation treatment for endometrial cancer].","authors":"","doi":"10.3760/cma.j.cn112141-20250106-00012","DOIUrl":"10.3760/cma.j.cn112141-20250106-00012","url":null,"abstract":"","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 2","pages":"83-93"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Exploration of CCL11 and sTNFR2 as potential biomarkers for the efficacy of lymphocyte immunotherapy in women with unexplained recurrent spontaneous abortion].","authors":"L Li, H Y Wang, J Qiao, R Li, P Liu","doi":"10.3760/cma.j.cn112141-20240511-00272","DOIUrl":"10.3760/cma.j.cn112141-20240511-00272","url":null,"abstract":"<p><p><b>Objective:</b> To explore biomarkers for the efficacy of lymphocyte immunotherapy (LIT) treating women with unexplained recurrent spontaneous abortion (URSA). <b>Methods:</b> Serum samples from 24 URSA potients who received LIT were collected at Peking University Third Hospital from December 2014 to June 2015. Semiquantitative sandwich-based antibody arrays containing 40 cytokines were used to screen target immune cytokines in the peripheral blood of URSA patients before and after LIT. Multifactor quantitative microsphere flow cytometry detection validated the levels of target cytokines. Based on the final pregnancy outcome after LIT, 24 URSA patients were divided into the full-term delivery group (15 cases) and the abortion group (9 cases). Furthermore, linear regression analysis were applied to evaluate the relationship between target cytokines and pregnancy outcomes. <b>Results:</b> Semiquantitative sandwich-based antibody arrays suggested that, among all 24 URSA patients included in this study, the intensities of the fluorescence signal were significantly lower post-LIT versus pre-LIT for the following cytokines: interleukin-15 (IL-15), monokine induced by γ-interferon (MIG), C-C motif chemokine ligand (CCL) 1 (all <i>P</i><0.05). In the full-term delivery group, the intensities of the fluorescence signal post-LIT were significantly lower than pre-LIT for the following cytokines: IL-15, CCL1, macrophage inflammatory protein (MIP) 1α (all <i>P</i><0.05). In the abortion group, the intensities of the fluorescence signal post-LIT were significantly lower than pre-LIT for the following cytokines: MIG, MIP-1δ (all <i>P</i><0.05). Linear regression analysis showed that the intensity of the fluorescence signal of CCL11 was increased and the intensity of the fluorescence signal of soluble tumor necrosis factor receptor 2 (sTNFR2) was decreased in the full-term delivery group after LIT, the differences were statistically significant (<i>P</i>=0.012, 0.029). Validation results of multifactor quantitative microsphere flow cytometry detection showed that the level of CCL11 was significantly increased (<i>P</i>=0.001) and the level of sTNFR2 was significantly decreased (<i>P</i>=0.001) in the full-term delivery group after LIT. <b>Conclusion:</b> CCL11 and sTNFR2 maybe serve as potential biomarkers that could predict pregnancy outcomes after LIT in women with URSA.</p>","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 1","pages":"24-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Age-stratified association between preconception body mass index and risk of macrosomia at delivery].","authors":"S W Wu, N Zhang","doi":"10.3760/cma.j.cn112141-20240807-00439","DOIUrl":"10.3760/cma.j.cn112141-20240807-00439","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the impact of preconception body mass index (BMI) on neonatal birth weight and the risk of macrosomia in pregnant women across various age groups. &lt;b&gt;Methods:&lt;/b&gt; A cohort study was conducted, selecting pregnant women who underwent their initial prenatal assessment at Beijing Obstetrics and Gynecology Hospital from September 1st, 2018 to March 31st, 2020. Relevant data were collected from the hospital's electronic medical record system. Logistic regression nested cubic spline was used to analyze the nonlinear association between preconception BMI and neonatal birth weight. Binary logistic regression was also employed to assess the association between preconception BMI and macrosomia risk. &lt;b&gt;Results:&lt;/b&gt; (1) A total of 13 015 pregnant women were examined, revealing an incidence of macrosomia of 6.33% (824/13 015). The preconception BMI of pregnant women in the macrosomia group was significantly higher than that in the non-macrosomia group [(23.1±3.4) vs (21.6±3.1) kg/m&lt;sup&gt;2&lt;/sup&gt;], and the age was significantly higher than that in the non-macrosomia group [(32.1±3.6) vs (31.7±3.7) years], the differences were statistically significant (all &lt;i&gt;P&lt;/i&gt;&lt;0.05). (2) Preconception BMI was positively correlated with neonatal birth weight. Pregnant women with preconception BMI of 15.0 kg/m&lt;sup&gt;2&lt;/sup&gt;, 20.0 kg/m&lt;sup&gt;2&lt;/sup&gt;, and 25.0 kg/m&lt;sup&gt;2&lt;/sup&gt; had decreased birth weight of 121 g (95%&lt;i&gt;CI&lt;/i&gt;: 35-183 g) and increased birth weights of 78 g (95%&lt;i&gt;CI&lt;/i&gt;: 54-102 g) and 182 g (95%&lt;i&gt;CI&lt;/i&gt;: 151-213 g), respectively, compared to those with a preconception BMI of 18.0 kg/m&lt;sup&gt;2&lt;/sup&gt;. (3) For each 1.0 kg/m&lt;sup&gt;2&lt;/sup&gt; increase in preconception BMI, the risk of macrosomia increased by 14% (&lt;i&gt;OR&lt;/i&gt;=1.14, 95%&lt;i&gt;CI&lt;/i&gt;: 1.11-1.16; &lt;i&gt;P&lt;/i&gt;&lt;0.001). When stratified by age, it was observed that elevated preconception BMI significantly increased the incidence of macrosomia in women aged 27-38 years. Among them, the risk of delivering macrosomia among 37 years old pregnant women was most affected by preconception BMI (&lt;i&gt;OR&lt;/i&gt;=1.33, 95%&lt;i&gt;CI&lt;/i&gt;: 1.17-1.51; &lt;i&gt;P&lt;/i&gt;&lt;0.001). (4) The stability and sensitivity analysis results showed that the preconception BMI of pregnant women with a preconception BMI of 18.0-&lt;25.0 kg/m&lt;sup&gt;2&lt;/sup&gt; had a significant impact on the risk of macrosomia (&lt;i&gt;OR&lt;/i&gt;=1.23, 95%&lt;i&gt;CI&lt;/i&gt;: 1.17-1.29; &lt;i&gt;P&lt;/i&gt;&lt;0.001), while the preconception BMI of other preconception BMI stratification pregnant women had no significant impact on the risk of macrosomia (all &lt;i&gt;P&lt;/i&gt;&gt;0.05). Hypertension disorders in pregnancy, gestational diabetes mellitus and abnormal blood lipid during pregnancy were not the mediators associated with preconception BMI and macrosomia. After excluding three factors respectively, the impact of preconception BMI on the risk of macrosomia was the same as before (&lt;i&gt;OR&lt;/i&gt;=1.14, 95%&lt;i&gt;CI&lt;/i&gt;: 1.11-1.16; &lt;i&gt;P&lt;/i&gt;&lt;0.001). &lt;b&gt;Conclusions:&lt;/b&gt; Preconception BMI is linked to neonatal birth wei","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 1","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research advances of diagnosis and treatment of rectovaginal septum endometriosis].","authors":"E N Liu, F Miao, Y F Zhou","doi":"10.3760/cma.j.cn112141-20240805-00436","DOIUrl":"10.3760/cma.j.cn112141-20240805-00436","url":null,"abstract":"","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 1","pages":"66-70"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress in neoadjuvant therapy for epithelial ovarian cancer].","authors":"H Y Dong, L Li","doi":"10.3760/cma.j.cn112141-20240930-00532","DOIUrl":"10.3760/cma.j.cn112141-20240930-00532","url":null,"abstract":"","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 1","pages":"71-78"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Coexistence of development and expectation, balancing tasks and responsibilities].","authors":"J H Lang","doi":"10.3760/cma.j.cn112141-20241112-00601","DOIUrl":"https://doi.org/10.3760/cma.j.cn112141-20241112-00601","url":null,"abstract":"","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on complex cesarean section (2024)].","authors":"","doi":"10.3760/cma.j.cn112141-20241014-00552","DOIUrl":"10.3760/cma.j.cn112141-20241014-00552","url":null,"abstract":"","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 1","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Correlation between uterine volume and intrauterine adhesion: a propensity score matching analysis].","authors":"Q Xu, H Duan, Y Y An, L Gan","doi":"10.3760/cma.j.cn112141-20240814-00454","DOIUrl":"10.3760/cma.j.cn112141-20240814-00454","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the correlation between uterine volume and intrauterine adhesion (IUA). <b>Methods:</b> From June 2018 to November 2019, totally 7 007 patients who underwent hysteroscopy in outpatient operating rooms of Gynecological Minimally Invasive Center, Beijing Obstetrics and Gynecology Hospital were retrospectively analyzed<i>.</i> Patients of reproductive age with IUA without uterine fibroids and adenomyosis were selected as IUA group, and patients of reproductive age without uterine fibroids and adenomyosis without IUA during the same period were selected as the control group. The propensity score matching (PSM) method was used to perform 1∶1 matching for the two groups of patients, matching variables included age, height, weight, body mass index (BMI), gravidity, parity, and number of abortion curettage. Whether there was any difference in uterine volume between the two groups of patients was compared, and whether uterine volume was an influencing factor of IUA was explored. The patients in IUA group were also categorized into mild, moderate and severe to explore whether uterine volume influenced the severity of IUA. <b>Results:</b> (1) After inclusion and exclusion criteria, 351 patients were included in IUA group and 2 986 patients in the control group. With PSM, 327 patients in IUA group and 327 patients in the control group were finally enrolled in this study. There were no statistically significant differences in age, height, weight, BMI, gravidity, parity, and number of abortion curettage between the two groups of patients after matching (all <i>P></i>0.05). (2) After PSM, there was a significant difference between the uterine volume of IUA group (median: 44.23 cm³) and the uterine volume of the control group (median: 57.20 cm³; <i>P</i><0.001). (3) Reduced uterine volume (<i>OR</i>=0.961, 95%<i>CI</i>: 0.952-0.970) was an independent risk factor for IUA (<i>P</i><0.001). (4) Uterine volume had a significant effect on the severity of IUA (<i>P</i><0.001), the larger the uterine volume (<i>B</i>=-0.030, 95%<i>CI</i>: -0.044 to -0.017), the less severe the IUA. <b>Conclusions:</b> Reduced uterine volume is an independent risk factor for IUA, and uterine volume has a significant effect on the severity of IUA. In patients with small uterine volume size, primary and secondary prevention of IUA should be emphasized.</p>","PeriodicalId":10050,"journal":{"name":"中华妇产科杂志","volume":"60 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}