Engineering Microbiology最新文献_第9页

Aquaculture sustainability through alternative dietary ingredients: Microalgal value-added products 通过替代膳食成分实现水产养殖的可持续性:微藻增值产品

Engineering Microbiology Pub Date : 2022-12-01 DOI: 10.1016/j.engmic.2022.100049

John N. Idenyi , Jonathan C. Eya , Amechi S. Nwankwegu , Emeka G. Nwoba

{"title":"Aquaculture sustainability through alternative dietary ingredients: Microalgal value-added products","authors":"John N. Idenyi , Jonathan C. Eya , Amechi S. Nwankwegu , Emeka G. Nwoba","doi":"10.1016/j.engmic.2022.100049","DOIUrl":"https://doi.org/10.1016/j.engmic.2022.100049","url":null,"abstract":"<div><p>Aquaculture contributes remarkably to the global economy and food security through seafood production, an important part of the global food supply chain. The success of this industry depends heavily on aquafeeds, and the nutritional composition of the feed is an important factor for the quality, productivity, and profitability of aquaculture species. The sustainability of the aquaculture industry depends on the accessibility of quality feed ingredients, such as fishmeal and fish oil. These traditional feedstuffs are under increasing significant pressure due to the rapid expansion of aquaculture for human consumption and the decline of natural fish harvest. In this review, we evaluated the development of microalgal molecules in aquaculture and expanded the use of these high-value compounds in the production of aquaculture diets. Microalgae-derived functional ingredients emerged as one of the promising alternatives for aquafeed production with positive health benefits. Several compounds found in microalgae, including carotenoids (lutein, astaxanthin, and β-carotene), essential amino acids (leucine, valine, and threonine), β-1–3-glucan, essential oils (docosahexaenoic acid and eicosapentaenoic acid), minerals, and vitamins, are of high nutritional value to aquaculture.</p></div>","PeriodicalId":100478,"journal":{"name":"Engineering Microbiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667370322000406/pdfft?md5=06265d972f4fa1627cbf4a7604ac81c7&pid=1-s2.0-S2667370322000406-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71894967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Bioproduction of monoterpene indole alkaloids in a single cell factory 单细胞工厂中单萜吲哚生物碱的生物生产

Engineering Microbiology Pub Date : 2022-10-01 DOI: 10.1016/j.engmic.2022.100050

Jian-Ping Huang, Sheng-Xiong Huang

引用次数: 3

The type IX secretion system: Insights into its function and connection to glycosylation in Cytophaga hutchinsonii IX型分泌系统在胡氏细胞吞噬中的作用及其与糖基化的关系

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100038

Wenxia Song, Xueke Zhuang, Yahong Tan, Qingsheng Qi, Xuemei Lu

{"title":"The type IX secretion system: Insights into its function and connection to glycosylation in Cytophaga hutchinsonii","authors":"Wenxia Song, Xueke Zhuang, Yahong Tan, Qingsheng Qi, Xuemei Lu","doi":"10.1016/j.engmic.2022.100038","DOIUrl":"https://doi.org/10.1016/j.engmic.2022.100038","url":null,"abstract":"<div><p>The recently discovered type IX secretion system (T9SS) is limited to the Bacteroidetes phylum. <em>Cytophaga hutchinsonii</em>, a member of the Bacteroidetes phylum widely spread in soil, has complete orthologs of T9SS components and many T9SS substrates. <em>C. hutchinsonii</em> can efficiently degrade crystalline cellulose using a novel strategy, in which bacterial cells must be in direct contact with cellulose. It can rapidly glide over surfaces via unclear mechanisms. Studies have shown that T9SS plays an important role in cellulose degradation, gliding motility, and ion assimilation in <em>C. hutchinsonii</em>. As reported recently, T9SS substrates are <em>N</em>- or <em>O</em>-glycosylated at their C-terminal domains (CTDs), with <em>N</em>-glycosylation being related to the translocation and outer membrane anchoring of these proteins. These findings have deepened our understanding of T9SS in <em>C. hutchinsonii</em>. In this review, we focused on the research progress on diverse substrates and functions of T9SS in <em>C. hutchinsonii</em> and the glycosylation of its substrates. A model of T9SS functions and the glycosylation of its substrates was proposed.</p></div>","PeriodicalId":100478,"journal":{"name":"Engineering Microbiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667370322000297/pdfft?md5=434ec9b499cefc5eb233b60b01f5e3ca&pid=1-s2.0-S2667370322000297-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71901146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methods of DNA Introduction for the Engineering of Commensal Microbes 共生微生物工程中DNA导入方法的研究

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100048

Dake Liu, Nicole Siguenza, A. Zarrinpar, Yousong Ding

引用次数: 3

Aquaculture sustainability through alternative dietary ingredients: Microalgal value-added products 通过替代膳食成分实现水产养殖的可持续性:微藻增值产品

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100049

J. N. Idenyi, J. Eya, A. S. Nwankwegu, E. Nwoba

引用次数: 8

Discovery and analysis of a new class of triterpenes derived from hexaprenyl pyrophosphate 一类新的焦磷酸己烯基三萜的发现与分析

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100035

Dan Hu

引用次数: 1

Peptaibols: Diversity, bioactivity, and biosynthesis 肽：多样性、生物活性和生物合成

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100026

Xuewen Hou , Ruonan Sun , Yanyan Feng , Runfang Zhang , Tianjiao Zhu , Qian Che , Guojian Zhang , Dehai Li

引用次数: 10

Engineered bacteria as drug delivery vehicles: Principles and prospects 工程细菌作为药物传递载体:原理与展望

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100034

Yuxi Zhou , Yong Han

引用次数: 12

Recent Developments in the Identification and Biosynthesis of Antitumor Drugs Derived from Microorganisms 微生物源抗肿瘤药物的鉴定与生物合成研究进展

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100047

Qi Gao, S. Deng, Tianyu Jiang

引用次数: 2

Copper-radical oxidases: A diverse group of biocatalysts with distinct properties and a broad range of biotechnological applications 铜自由基氧化酶:一组不同的生物催化剂具有不同的性质和广泛的生物技术应用

Engineering Microbiology Pub Date : 2022-09-01 DOI: 10.1016/j.engmic.2022.100037

Katja Koschorreck , Saadet Alpdagtas , Vlada B. Urlacher

{"title":"Copper-radical oxidases: A diverse group of biocatalysts with distinct properties and a broad range of biotechnological applications","authors":"Katja Koschorreck , Saadet Alpdagtas , Vlada B. Urlacher","doi":"10.1016/j.engmic.2022.100037","DOIUrl":"https://doi.org/10.1016/j.engmic.2022.100037","url":null,"abstract":"<div><p>Copper-radical oxidases (CROs) catalyze the two-electron oxidation of a large number of primary alcohols including carbohydrates, polyols and benzylic alcohols as well as aldehydes and α-hydroxy-carbonyl compounds while reducing molecular oxygen to hydrogen peroxide. Initially, CROs like galactose oxidase and glyoxal oxidase were identified only in fungal secretomes. Since the last decade, their representatives have also been identified in some bacteria. CROs are grouped in the AA5 family of “auxiliary activities” in the database of Carbohydrate-Active enzymes. Despite low overall sequence similarity and different substrate specificities, sequence alignments and the solved crystal structures revealed a conserved architecture of the active sites in all CROs, with a mononuclear copper ion coordinated to an axial tyrosine, two histidines, and a cross-linked cysteine-tyrosyl radical cofactor. This unique post-translationally modified protein cofactor has attracted much attention in the past, which resulted in a large number of reports that shed light on key steps of the catalytic cycle and physico-chemical properties of CROs. Thanks to their broad substrate spectrum accompanied by the only need for molecular oxygen for catalysis, CROs since recently experience a renaissance and have been applied in various biocatalytic processes. This review provides an overview of the structural features, catalytic mechanism and substrates of CROs, presents an update on the engineering of these enzymes to improve their expression in recombinant hosts and to enhance their activity, and describes their potential fields of biotechnological application.</p></div>","PeriodicalId":100478,"journal":{"name":"Engineering Microbiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667370322000285/pdfft?md5=2ab20458bb384f206e67380c0ffa3852&pid=1-s2.0-S2667370322000285-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71901148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4