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Entrevista motivacional y adherencia terapéutica en los pacientes con enfermedad inflamatoria intestinal 炎症性肠病患者的动机性访谈与治疗依从性
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2016.12.004
P. Lusilla-Palacios , F. Gomollón
{"title":"Entrevista motivacional y adherencia terapéutica en los pacientes con enfermedad inflamatoria intestinal","authors":"P. Lusilla-Palacios ,&nbsp;F. Gomollón","doi":"10.1016/j.eii.2016.12.004","DOIUrl":"10.1016/j.eii.2016.12.004","url":null,"abstract":"<div><p>Inflammatory bowel disease (IBD) is a chronic condition and establishing a relationship of trust with the patient is key in facilitating treatment adherence. 70% of specialists are aware of the fact that good communication with patients encourages adherence to treatment but only one in ten professional admit to having received specific training.</p><p>Motivational interviewing (MI) is an easy-to-learn method. Its use in various medical disciplines is associated with better adherence and a change in unhealthy habits. This paper provides a brief review of the strategic principles of MI and how it can be applied to daily practice for IBS.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.12.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85108327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estudios epidemiológicos: tipos, diseño e interpretación 流行病学研究:类型、设计和解释
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2017.03.001
V. Hernández
{"title":"Estudios epidemiológicos: tipos, diseño e interpretación","authors":"V. Hernández","doi":"10.1016/j.eii.2017.03.001","DOIUrl":"10.1016/j.eii.2017.03.001","url":null,"abstract":"<div><p>There has been renewed interest in the recent years, in the epidemiology of inflammatory bowel diseases. The aim of this article is present a review of the epidemiological method and the epidemiological studies, showing the strengths and limitations of each of them, with examples in the field of inflammatory bowel diseases in order to understand and analyse these types of studies.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2017.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83928792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigación clínica en 2016: artículos destacados 2016年临床研究:专题文章
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2017.03.002
G. Trejo, A. Marco-Marqués, S.V. Hernández, M.M. Boscá-Watts
{"title":"Investigación clínica en 2016: artículos destacados","authors":"G. Trejo,&nbsp;A. Marco-Marqués,&nbsp;S.V. Hernández,&nbsp;M.M. Boscá-Watts","doi":"10.1016/j.eii.2017.03.002","DOIUrl":"10.1016/j.eii.2017.03.002","url":null,"abstract":"<div><p>Many high quality articles were published in 2016 regarding Crohn's disease (CD) and ulcerative colitis (UC). The importance of diet and microbes in inflammatory bowel disease (IBD), the burden of IBD on patient quality of life are some of the relevant topics. The role of calprotectin or the possibility of using PET for follow-up is also highlighted.</p><p>IBD treatment has been the focus of numerous clinical trials, which have consolidated infliximab (suggesting levels in week 2), adalimumab, and golimumab as front-line treatment. The use of ustekinumab in CD is supported, with methotrexate being left as a last resort, except in the case of arthropathy. Other treatments investigated that are worth mentioning were stem cells, other biosimilar, and new drugs.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2017.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74517089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trombosis venosa cerebral en la enfermedad de Crohn refractaria a tratamiento: aportación de un caso y revisión de una serie de casos pediátricos 难治性克罗恩病的脑静脉血栓形成:一个病例的贡献和一些儿科病例的回顾
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2017.04.003
M.S. Hoyos , E.M. Balmaseda , C. Gutiérrez , E. Medina , M.C. Escudero , C. Medina , S. García
{"title":"Trombosis venosa cerebral en la enfermedad de Crohn refractaria a tratamiento: aportación de un caso y revisión de una serie de casos pediátricos","authors":"M.S. Hoyos ,&nbsp;E.M. Balmaseda ,&nbsp;C. Gutiérrez ,&nbsp;E. Medina ,&nbsp;M.C. Escudero ,&nbsp;C. Medina ,&nbsp;S. García","doi":"10.1016/j.eii.2017.04.003","DOIUrl":"10.1016/j.eii.2017.04.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Neurological manifestations in patients with inflammatory bowel disease are more frequent than previously believed. In some cases the neurological symptoms can precede the diagnosis of inflammatory bowel disease. An early and correct diagnosis of these problems is important, since they can be serious and irreversible. Cerebrovascular involvement is rare, being more frequent in ulcerative colitis, and is favoured by a multifactorial hypercoagulability state.</p></div><div><h3>Patients and methodology</h3><p>The case is presented on a paediatric patient with refractory Crohn's disease who developed cerebral venous thrombosis three years after onset of the bowel disease. A review is also presented on all the cases described in the literature and a comparative study with our case was performed.</p></div><div><h3>Results</h3><p>The review found a total of 18 paediatric age patients diagnosed with inflammatory bowel disease who suffered thrombosis of the cerebral venous sinuses. Most of the patients had ulcerative colitis (61.1%). An analysis was made of the presence of the most common risk factors such as thrombocytosis or iron-deficiency anaemia, as well as genetic coagulation disorders. The treatment used in the most of the cases included heparin and oral anticoagulants. The outcome of the neurological manifestations was favourable in more than 75% of the cases.</p></div><div><h3>Conclusion</h3><p>Cerebrovascular involvement is rare, but an early diagnosis and treatment are essential for a favourable outcome.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2017.04.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73433222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Metotrexato en la enfermedad inflamatoria intestinal pediátrica 甲氨蝶呤在小儿炎症性肠病中的应用
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2016.12.003
V.M. Navas-López , N. Ramos-Rueda , G. Pujol-Muncunill , J. Martín de Carpi
{"title":"Metotrexato en la enfermedad inflamatoria intestinal pediátrica","authors":"V.M. Navas-López ,&nbsp;N. Ramos-Rueda ,&nbsp;G. Pujol-Muncunill ,&nbsp;J. Martín de Carpi","doi":"10.1016/j.eii.2016.12.003","DOIUrl":"10.1016/j.eii.2016.12.003","url":null,"abstract":"<div><p>Following the notification from the FDA on the risk of hepatosplenic T-cell lymphoma after using thiopurines, it has found a growing trend of prescribing MTX in paediatric inflammatory bowel disease, becoming the first-line immunomodulator in up to 60% of PIBD patients in 2010. The basic mechanism of action by which MTX acts in IBD and rheumatologic diseases is currently unknown, but it seems not to be exclusively by inhibiting the metabolism of folates. Side effects (nausea/vomiting, hypertransaminasaemia, leukopenia and thrombocytopenia) of treatment with MTX are currently the major factor that has conditioned the widespread use of MTX in PIBD. The purpose of this manuscript is to describe the pharmacological aspects of MTX, review the effectiveness of MTX in paediatric CD and UC in both mono and combination therapy, and highlight the most important aspects in terms of side effects and their management.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.12.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83049556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Afectación de la vía aérea alta en enfermedad inflamatoria intestinal. Descripción de 2 casos 炎症性肠病对上呼吸道的影响。2例描述
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2016.12.006
A. Elorza , I. Rodríguez-Lago , P. Gisasola , I. Gochi , A. Bernal , J.L. Cabriada
{"title":"Afectación de la vía aérea alta en enfermedad inflamatoria intestinal. Descripción de 2 casos","authors":"A. Elorza ,&nbsp;I. Rodríguez-Lago ,&nbsp;P. Gisasola ,&nbsp;I. Gochi ,&nbsp;A. Bernal ,&nbsp;J.L. Cabriada","doi":"10.1016/j.eii.2016.12.006","DOIUrl":"10.1016/j.eii.2016.12.006","url":null,"abstract":"<div><p>Inflammatory bowel disease is a chronic disease that primarily affects the gastrointestinal tract. Extraintestinal manifestations are frequent and can affect any organ, but those that affect the respiratory tract are uncommon. In these cases, the lower respiratory tract tends to be affected, usually with bronchiectasis and chronic bronchitis. It has been more often described in patients with ulcerative colitis.</p><p>We herein report the cases of two patients with inflammatory bowel disease with upper respiratory tract involvement treated in our hospital. Both cases were treated with systemic corticotherapy and required a tracheostomy. The first case presented with subglottic stenosis requiring dilation with a Foley catheter. We have conducted a review on the evidence available of the main characteristics of these manifestations, as well as its diagnosis and treatment according to the available case series.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.12.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80482013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uso de adalimumab durante la gestación en la enfermedad de Crohn 阿达木单抗在克罗恩病妊娠期间的使用
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2016.12.005
I. Iranzo González-Cruz , R. Gil Borrás , M.D. Martin Arranz , M.J. García Corbalán , M. Jaen Revuelta
{"title":"Uso de adalimumab durante la gestación en la enfermedad de Crohn","authors":"I. Iranzo González-Cruz ,&nbsp;R. Gil Borrás ,&nbsp;M.D. Martin Arranz ,&nbsp;M.J. García Corbalán ,&nbsp;M. Jaen Revuelta","doi":"10.1016/j.eii.2016.12.005","DOIUrl":"10.1016/j.eii.2016.12.005","url":null,"abstract":"<div><p>The presence of activity of inflammatory bowel disease during pregnancy can affect the course of the pregnancy. Therefore, the best advice is that conception occurs when the disease is in remission. A flare-up during pregnancy requires treatment as quickly as possible to induce remission and thus avoid any complications.</p><p>We report the case of a woman, who being treated with adalimumab, becomes pregnant and presents with a flare-up that requires a scale-up of treatment until the end of pregnancy. The end of pregnancy and childbirth occur without maternal and foetal complications.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.12.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83615794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Meningitis aguda por Listeria monocytogenes en paciente con hemocromatosis hereditaria y colitis ulcerosa en tratamiento con infliximab 英夫利昔单抗治疗遗传性血色素沉着症和溃疡性结肠炎患者的单核增生李斯特菌急性脑膜炎
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2017.04.002
A. Sánchez , P. Ramírez de la Piscina , I.M. Duca , S. Estrada , M.R. Calderón , M. Salvador , E. Delgado , F. García Campos
{"title":"Meningitis aguda por Listeria monocytogenes en paciente con hemocromatosis hereditaria y colitis ulcerosa en tratamiento con infliximab","authors":"A. Sánchez ,&nbsp;P. Ramírez de la Piscina ,&nbsp;I.M. Duca ,&nbsp;S. Estrada ,&nbsp;M.R. Calderón ,&nbsp;M. Salvador ,&nbsp;E. Delgado ,&nbsp;F. García Campos","doi":"10.1016/j.eii.2017.04.002","DOIUrl":"10.1016/j.eii.2017.04.002","url":null,"abstract":"<div><p>Hereditary haemochromatosis (HH) is an autosomal recessive genetic disease related to iron overload due to a mutation of the HFE gene located in chromosome 6. This chromosome is located on locus HL-DR, which is the same as ulcerative colitis. This could mean that patients who have HH have a greater predisposition to suffer an inflammatory bowel disease. In addition, both diseases increase the risk of infections by intracellular bacteria, such as <em>Listeria monocytogenes</em>.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2017.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85884116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Papel de las pruebas funcionales anorrectales en la enfermedad perianal: implicaciones para la práctica clínica 肛肠功能检测在肛周疾病中的作用:对临床实践的启示
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2016.12.007
P. Mas Mercader, M. Mínguez Pérez
{"title":"Papel de las pruebas funcionales anorrectales en la enfermedad perianal: implicaciones para la práctica clínica","authors":"P. Mas Mercader,&nbsp;M. Mínguez Pérez","doi":"10.1016/j.eii.2016.12.007","DOIUrl":"10.1016/j.eii.2016.12.007","url":null,"abstract":"<div><p>Patients with inflammatory bowel disease and concomitant perianal disease may present with urgency and/or faecal incontinence due to both the underlying inflammatory process and possible abnormalities in anorectal function, or by affecting rectal compliance. Anorectal function studies show that in Crohn's disease anal resting pressure and squeeze pressure are decreased in patients with previous surgery on the perianal region. In ulcerative colitis there is no published data on the capacity of the anal sphincter in patients with ulcerative colitis and perianal disease. Anal pressures are normal in patients with ulcerative colitis even during flare-ups with a dramatic decrease in rectal compliance contributing to urgency and incontinence in these patients. Likewise, increased fatigability of the striated sphincter muscle, observed in both patients with Crohn's disease and with ulcerative colitis, is associated with faecal urgency or incontinence. In conclusion, it might be useful to evaluate anorectal function in those patients who will be operated on due to injury in the perianal region and prior to bowel transit restorative surgery.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.12.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79928626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuevas dianas terapéuticas en la enfermedad inflamatoria intestinal 炎症性肠病的新治疗目标
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2017-09-01 DOI: 10.1016/j.eii.2017.04.001
F. Muñoz
{"title":"Nuevas dianas terapéuticas en la enfermedad inflamatoria intestinal","authors":"F. Muñoz","doi":"10.1016/j.eii.2017.04.001","DOIUrl":"10.1016/j.eii.2017.04.001","url":null,"abstract":"<div><p>In spite of the best possible optimisation of the available drugs in inflammatory bowel disease (IBD), an important group of patients will require new therapeutic alternatives. Fortunately, there are already new drugs such as vedolizumab or ustekinumab, but, there are many more that will be available in a near future. In this article, a review is made of the evidence and the possible uses of these alternatives. Some of them are drugs that inhibit white cell adhesion, the JAK-kinase inhibitors, the anti-cytokines (especially, ustekinumab), and mongersen.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2017.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81031562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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