Nuevas dianas terapéuticas en la enfermedad inflamatoria intestinal

In spite of the best possible optimisation of the available drugs in inflammatory bowel disease (IBD), an important group of patients will require new therapeutic alternatives. Fortunately, there are already new drugs such as vedolizumab or ustekinumab, but, there are many more that will be available in a near future. In this article, a review is made of the evidence and the possible uses of these alternatives. Some of them are drugs that inhibit white cell adhesion, the JAK-kinase inhibitors, the anti-cytokines (especially, ustekinumab), and mongersen.