Investigación clínica en 2016: artículos destacados

G. Trejo, A. Marco-Marqués, S.V. Hernández, M.M. Boscá-Watts
{"title":"Investigación clínica en 2016: artículos destacados","authors":"G. Trejo,&nbsp;A. Marco-Marqués,&nbsp;S.V. Hernández,&nbsp;M.M. Boscá-Watts","doi":"10.1016/j.eii.2017.03.002","DOIUrl":null,"url":null,"abstract":"<div><p>Many high quality articles were published in 2016 regarding Crohn's disease (CD) and ulcerative colitis (UC). The importance of diet and microbes in inflammatory bowel disease (IBD), the burden of IBD on patient quality of life are some of the relevant topics. The role of calprotectin or the possibility of using PET for follow-up is also highlighted.</p><p>IBD treatment has been the focus of numerous clinical trials, which have consolidated infliximab (suggesting levels in week 2), adalimumab, and golimumab as front-line treatment. The use of ustekinumab in CD is supported, with methotrexate being left as a last resort, except in the case of arthropathy. Other treatments investigated that are worth mentioning were stem cells, other biosimilar, and new drugs.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"16 3","pages":"Pages 106-113"},"PeriodicalIF":0.0000,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2017.03.002","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Enfermedad Inflamatoria Intestinal al Día","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1696780117300210","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Many high quality articles were published in 2016 regarding Crohn's disease (CD) and ulcerative colitis (UC). The importance of diet and microbes in inflammatory bowel disease (IBD), the burden of IBD on patient quality of life are some of the relevant topics. The role of calprotectin or the possibility of using PET for follow-up is also highlighted.

IBD treatment has been the focus of numerous clinical trials, which have consolidated infliximab (suggesting levels in week 2), adalimumab, and golimumab as front-line treatment. The use of ustekinumab in CD is supported, with methotrexate being left as a last resort, except in the case of arthropathy. Other treatments investigated that are worth mentioning were stem cells, other biosimilar, and new drugs.

2016年临床研究:专题文章
2016年发表了许多关于克罗恩病(CD)和溃疡性结肠炎(UC)的高质量文章。饮食和微生物在炎症性肠病(IBD)中的重要性,IBD对患者生活质量的负担是一些相关主题。钙保护素的作用或使用PET进行随访的可能性也被强调。IBD治疗一直是许多临床试验的重点,这些临床试验已经巩固了英夫利昔单抗(建议第2周的水平)、阿达木单抗和戈利木单抗作为一线治疗。支持在CD中使用ustekinumab,甲氨蝶呤作为最后的手段,除非是关节病。其他值得一提的治疗方法包括干细胞、其他生物仿制药和新药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信