Comparative Biochemistry and Physiology Part B: Comparative Biochemistry最新文献_第9页

Isolation and characterization of a 21 kDa whey protein in Rhesus monkey (Macaca mulatta) milk 恒河猴(Macaca mulatta)牛奶中21 kDa乳清蛋白的分离与鉴定

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90099-X

Clemens Kunz , Bo Lönnerdal

引用次数: 11

A decrease of free radical production near critical targets as a cause of maximum longevity in animals 自由基减少:动物在关键目标附近自由基产生的减少，是最大寿命的原因

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90103-1

G. Barja, S. Cadenas, C. Rojas, M. López-Torres, R. Pèrez-Campo

{"title":"A decrease of free radical production near critical targets as a cause of maximum longevity in animals","authors":"G. Barja, S. Cadenas, C. Rojas, M. López-Torres, R. Pèrez-Campo","doi":"10.1016/0305-0491(94)90103-1","DOIUrl":"10.1016/0305-0491(94)90103-1","url":null,"abstract":"<div>A comprehensive study was performed on the brains of various vertebrate species showing different life energy potentials in order to find out if free radicals are important determinants of species-specific maximum life span. Brain superoxide dismutase, catalase, Se-dependent and independent GSH-peroxidases, GSH-reductase, and ascorbic acid showed significant inverse correlations with maximum longevity, whereas GSH, uric acid, GSSG/GSH, in vitro peroxidation (thiobarbituric acid test), and malondialdehyde (measured by HPLC), did not correlate with maximum life span. Superoxide dismutase, catalase, GSH-peroxidase, GSH and ascorbate results agree with those previously reported in various independent works using different animal species. GSSG/GSH, and true malondialdehyde (HPLC) results are reported for the first time in relation to maximum longevity. The results suggest that longevous species simultaneously show low antioxidant concentrations and low levels of in vivo free radical production (a low free radical turnover) in their tissues. The “free radical production hypothesis of aging” is proposed: a decrease in oxygen radical production per unit of O2 consumption near critical DNA targets (mitochondria or nucleus) increases the maximum life span of extraordinarily long-lived species like birds, primates, and man. Free radical production near these DNA sites would be a main factor responsible for aging in all the species, in those following Pearl's (Rubner's) metabolic rule as well as in those not following it.</div>","PeriodicalId":100294,"journal":{"name":"Comparative Biochemistry and Physiology Part B: Comparative Biochemistry","volume":"108 4","pages":"Pages 501-512"},"PeriodicalIF":0.0,"publicationDate":"1994-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0305-0491(94)90103-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18947163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 109

Patterns of lactate and sorbitol dehydrogenase gene expression during the development of interspecific Rasbora hybrids 种间杂交种发育过程中乳酸脱氢酶和山梨糖醇脱氢酶基因的表达模式

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90096-5

Jack S. Frankel

引用次数: 1

Prolactin gene expression and changes of prolactin pituitary level during the seasonal acclimatization of the carp 鲤季节性适应过程中催乳素基因表达及垂体催乳素水平的变化

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90109-0

Jaime Figueroa, Alfredo Molina, Marco Alvarez, Julieta Villanueva, Ariel Reyes, Gloria León, Manuel Krauskopf

{"title":"Prolactin gene expression and changes of prolactin pituitary level during the seasonal acclimatization of the carp","authors":"Jaime Figueroa, Alfredo Molina, Marco Alvarez, Julieta Villanueva, Ariel Reyes, Gloria León, Manuel Krauskopf","doi":"10.1016/0305-0491(94)90109-0","DOIUrl":"10.1016/0305-0491(94)90109-0","url":null,"abstract":"<div>The effect of seasonal acclimatization on the extent of prolactin (PRL) gene expression and on the content of this was studied in summer- and winter-carp (Cyprinus carpio) hormone pituitary glands. PRL content in the rostral pars distalis (RPD) was evaluated by immunocytochemistry using antibodies against a cross-linked synthetic peptide comprising the sequence of 15 amino acids which conform to the primary structure of carp PRL. To assess the level of PRL gene transcription, a 24-mer synthetic oligonucleotide probe whose sequence included nucleotides 2041–2064 located in exon V of the carp PRL gene, was used. Employing in situ hybridization assays, a high expression of PRL mRNA was observed in the RPD of summer-acclimatized carp. A negligible level of transcription was observed in tissue sections of pituitary glands from winter-acclimatized carp. Concurrently, immunodetection of the PRL-producing cells in the RPD revealed that the pituitary hormone level was significantly higher in the warm season-adapted carp.</div>","PeriodicalId":100294,"journal":{"name":"Comparative Biochemistry and Physiology Part B: Comparative Biochemistry","volume":"108 4","pages":"Pages 551-560"},"PeriodicalIF":0.0,"publicationDate":"1994-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0305-0491(94)90109-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18952361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28

Lactate dehydrogenase, alanopine dehydrogenase and octopine dehydrogenase from the heart of Concholepas concholepas (Gastropoda: Muricidae) 腹足目:蠓科(腹足目:蠓科)心乳酸脱氢酶、丙氨酸脱氢酶和章鱼碱脱氢酶

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90108-2

Nelson Carvajal, Edgardo Vega, Alejandro Erices, Daniel Bustos, Claudio Torres

{"title":"Lactate dehydrogenase, alanopine dehydrogenase and octopine dehydrogenase from the heart of Concholepas concholepas (Gastropoda: Muricidae)","authors":"Nelson Carvajal, Edgardo Vega, Alejandro Erices, Daniel Bustos, Claudio Torres","doi":"10.1016/0305-0491(94)90108-2","DOIUrl":"10.1016/0305-0491(94)90108-2","url":null,"abstract":"<div>Alanopine dehydrogenase, octopine dehydrogenase and lactate dehydrogenase activities were detected in the heart of C. concholepas. As determined by gel filtration on Sephadex G-100, the molecular weights (Mr) were 85,000, 42,000 and 52,000 for lactate dehydrogenase, alanopine dehydrogenase and octopine dehydrogenase, respectively. Substrate inhibition of the opine dehydrogenases was observed at high concentrations of both pyruvate and the corresponding amino acid (alanine or arginine). Moderate substrate inhibition of lactate dehydrogenase by pyruvate was observed; Km values for lactate and NAD+ were unusually high. Alanoonine dehydrogenase was very specific for alanine and glycine was not a substrate for this enzyme. In addition to arginine, lysine was also a substrate for octopine dehydrogenase. Possible functions of the pyruvate reductases are discussed in connection with adaptation to anoxia and other regulatory processes in the heart of C. concholepas.</div>","PeriodicalId":100294,"journal":{"name":"Comparative Biochemistry and Physiology Part B: Comparative Biochemistry","volume":"108 4","pages":"Pages 543-550"},"PeriodicalIF":0.0,"publicationDate":"1994-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0305-0491(94)90108-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75116780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Polysome profiles in awake and estivating snails (Otala lactea) 醒蜗牛和活动蜗牛的多体分布

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90095-7

Andrew A. Hobbs, Janet M. Attwood, Michael Guppy

引用次数: 6

Purification and characterization of multifunctional enzyme from mouse liver peroxisomes 小鼠肝脏过氧化物酶体多功能酶的纯化及特性研究

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90100-7

Annika Stark, Johan Meijer

引用次数: 3

2-Methylbutyryl-CoA: succinate acyl-CoA transferase activity and function in Ascaris suum muscle 2-甲基丁基辅酶a:琥珀酸酰基辅酶a转移酶在猪蛔虫肌肉中的活性和功能

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90104-X

Howard J. Saz, Becky S. deBruyn

引用次数: 1

Comparative study of the endemic freshwater fauna of Lake Baikal—V. Phospholipid and fatty acid composition of the deep-water amphipod crustacean Acanthogammarus (Brachyuropus) grewingkii 贝加尔湖特有淡水动物群的比较研究。深海片脚甲壳类棘鱼(Acanthogammarus)磷脂和脂肪酸组成

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90097-3

Valery M. Dembitsky , Andrey G. Kashin , Tomas Rezanka

引用次数: 15

Comparative biochemistry and physiology B bibliography 比较生物化学与生理学B参考书目

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-08-01 DOI: 10.1016/0305-0491(94)90112-0

引用次数: 0