{"title":"Pattern recognition for flow cytometric data analysis: A brief review","authors":"Ph.D. Gary C. Salzman","doi":"10.1016/S0197-1859(00)89169-4","DOIUrl":"10.1016/S0197-1859(00)89169-4","url":null,"abstract":"","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"18 3","pages":"Pages 21-28"},"PeriodicalIF":0.0,"publicationDate":"1998-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)89169-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81723432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ph.D., P.M.I.A.C. James B. Hendricks , M.D., M.I.A.C. Eva M. Wojcik
{"title":"Quantitative cytology and histology by laser scanning cytometry","authors":"Ph.D., P.M.I.A.C. James B. Hendricks , M.D., M.I.A.C. Eva M. Wojcik","doi":"10.1016/S0197-1859(00)89168-2","DOIUrl":"10.1016/S0197-1859(00)89168-2","url":null,"abstract":"","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"18 3","pages":"Pages 21-26"},"PeriodicalIF":0.0,"publicationDate":"1998-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)89168-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82652705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the T cell receptor (TCR) V beta repertoire in HIV disease","authors":"PhD J. Philip McCoy Jr.","doi":"10.1016/S0197-1859(00)89170-0","DOIUrl":"10.1016/S0197-1859(00)89170-0","url":null,"abstract":"","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"18 3","pages":"Pages 28-32"},"PeriodicalIF":0.0,"publicationDate":"1998-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)89170-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88374532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The cellular physiology of apoptosis mapped by multilaser flow cytometry","authors":"M.D. David W. Hedley","doi":"10.1016/S0197-1859(00)89164-5","DOIUrl":"10.1016/S0197-1859(00)89164-5","url":null,"abstract":"","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"18 1","pages":"Pages 1-7"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)89164-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86190296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel autoimmune targets and crossreactivity in myasthenia gravis","authors":"Mark A. Agius, Robert H. Fairclough","doi":"10.1016/S0197-1859(00)89167-0","DOIUrl":"10.1016/S0197-1859(00)89167-0","url":null,"abstract":"<div><p>The identification of the AChR as the antigenic target in the autoimmune disease MG stemmed from advances in understanding of the structure of the neuromuscular junction. The improved understanding of the structure of the synapse is being associated, concomitantly, with improved understanding of the antigenic targets of autoimmune disease of the neuromuscular junction. Intramolecular and inter-molecular spreading of antigenic targets appears to occur at the synapse and may explain the development of antibodies against cytoskeletal proteins in patients whose initial immune attack is directed against the AChR. Immune responses directed exclusively against these cytoskeletal proteins however may explain the phenomenon of seronegative myasthenia gravis. Molecular mimickry with crossreactive immune responses may explain the development of anti-AChR, anti-titin and anti-ryanodine receptor antibodies in patients with thymoma and MG. The chemical reactivity of proteins at the synapse may also render them susceptible to immune attack as a consequence of altered structure.</p></div>","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"18 1","pages":"Pages 16-19"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)89167-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89096269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complement receptor type 2 (CR2/CD21) as a central link between innate and acquired immunity","authors":"M.D. V. Michael Holers","doi":"10.1016/S0197-1859(00)89165-7","DOIUrl":"10.1016/S0197-1859(00)89165-7","url":null,"abstract":"<div><p>The complement system is activated by many molecules, including several important proteins of the innate immune system, that results in the covalent linkage of C3 activation fragments to Ag and/or Ab. Receptors for C3 activation fragments, especially CD21, play central roles in linking the B lymphocyte adaptive immune system to the complement system. CD21 deficient mice demonstrate pronounced immune defects. These defects are apparent because CD21 plays an important role in the activation of B lymphocytes, FDC, and likely T lymphocytes in vivo. Manipulation of CD21 activities by either blocking the binding of ligands to CD21, or targeting Ags to this receptor in vaccination strategies, are currently being explored as options to regulate several human immune responses. The regulation of immune responses through these and other strategies will likely further define the pivotal role CD21 plays in connecting innate to acquired immunity.</p></div>","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"18 1","pages":"Pages 7-10"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)89165-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74169612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modulation of complement-mediated tissue injury by IVIG","authors":"M.D. Michael M. Frank","doi":"10.1016/S0197-1859(00)80024-2","DOIUrl":"https://doi.org/10.1016/S0197-1859(00)80024-2","url":null,"abstract":"","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"17 12","pages":"Pages 166-168"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)80024-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90028528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kathryn Liszewski, V. Bala Subramanian, John P. Atkinson
{"title":"Complement inhibitors as therapeutic agents","authors":"M. Kathryn Liszewski, V. Bala Subramanian, John P. Atkinson","doi":"10.1016/S0197-1859(00)80025-4","DOIUrl":"https://doi.org/10.1016/S0197-1859(00)80025-4","url":null,"abstract":"<div><p>This report has described several currently evolving strategies and therapeutic agents designed to inhibit the complement system. Many others can be envisioned. Analagous to the utility of therapeutic agents that inhibit the coagulation cascade, it can be anticipated that complement inhibitors will find an important niche in our armamentarium of drugs to reduce undesirable inflammatory reactions</p></div>","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"17 12","pages":"Pages 168-173"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)80025-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90028529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modulation of complement activation in the management of disease processes","authors":"M.D. Barry Lee Myones (Associate Professor)","doi":"10.1016/S0197-1859(00)80023-0","DOIUrl":"10.1016/S0197-1859(00)80023-0","url":null,"abstract":"","PeriodicalId":100270,"journal":{"name":"Clinical Immunology Newsletter","volume":"17 12","pages":"Page 165"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0197-1859(00)80023-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88901394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}