Clinical and Public Health Guidelines最新文献

{"title":"Strengthening the Clinical Practice Guideline Ecosystem","authors":"Nan Yang,&nbsp;Dong Roman Xu,&nbsp;Janne Estill,&nbsp;Yaolong Chen","doi":"10.1002/gin2.70051","DOIUrl":"https://doi.org/10.1002/gin2.70051","url":null,"abstract":"<p>The concept of clinical practice guideline has existed for over 30 years, but guidelines still face numerous limitations, including low methodological quality, inadequate reporting transparency, slow implementation, and infrequent updates [<span>1, 2</span>]. There are several barriers in the dynamics between the different steps of the entire process, ranging from guideline development to implementation for which improvements are warranted [<span>3, 4</span>]. The establishment of a cohesive and well-coordinated guideline ecosystem could help to eliminate many barriers across the entire process from development to implementation and address the existing challenges.</p><p>The guideline ecosystem encompasses more than the above steps, but we believe these seven are the most fundamental ones and deserve particular attention. Each of the steps will require a thorough evaluation of the current situation, as well as the development of a standardised framework. A standardised framework will outline the relationships between the different steps of the guideline ecosystem, which in turn will help to promote the development, implementation, and updating of high-quality guidelines in a coordinated and transparent manner.</p><p><b>Nan Yang:</b> conceptualization, writing — original draft, visualization. <b>Dong Roman Xu:</b> writing — review and editing, supervision <b>Janne Estill:</b> methodology, writing — review and editing. <b>Yaolong Chen:</b> conceptualization, writing — review and editing, supervision, funding acquisition. All authors have read and approved the final manuscript.</p><p>The authors declare no conflict of interest. Yaolong Chen is the cofounder and cochair of RIGHT (Reporting Items for Practice Guidelines in Healthcare).</p><p>All relevant data are within the manuscript.</p>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70051","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145521839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Determinants That Influence the Development and Implementation of Evidence-Based Practice Guidelines During Health Emergencies: An Exploratory Sequential Mixed-Methods Study Protocol","authors":"Gonzalo Bravo-Soto,&nbsp;Shelly-Anne Li,&nbsp;Gordon Guyatt,&nbsp;Nancy Santesso,&nbsp;Susan M. Jack,&nbsp;Thomas Agoritsas,&nbsp;Francois Lamontagne,&nbsp;John Lavis,&nbsp;Reem A. Mustafa,&nbsp;Bram Rochwerg,&nbsp;Wojtek Wiercioch,&nbsp;Linan Zeng,&nbsp;Ludovic Reveiz,&nbsp;Romina Brignardello-Petersen","doi":"10.1002/gin2.70047","DOIUrl":"https://doi.org/10.1002/gin2.70047","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The COVID-19 pandemic highlighted the crucial role of evidence-based practice guidelines (EBPGs) in healthcare systems. Reliable and timely guidelines are essential in health emergencies. This study aims to identify and comprehensively understand the determinants that influence the development and implementation of EBPGs during health emergencies from the perspective of guideline developers and implementers. In this article, we describe the study protocol.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methodology</h3>\u0000 \u0000 <p>We will conduct an exploratory sequential mixed-methods study composed of four phases: (I) a qualitative descriptive study to document the experiences of guideline developers and implementers and use this data to generate a list of determinants that influence the development and implementation of EBPG; (II) exploratory integration for survey development and validation using the data of phase I; (III) cross-sectional study to administer the survey to a large sample and estimate the frequency and perceived impact of those determinants; (IV) interpretation of the results: a combination of qualitative and quantitative findings through the narrative description and joint displays to generate a comprehensive understanding of those determinants. We will explore if results vary across subgroups of interest (participants' roles, gender, and type of organization). We will include people worldwide from five groups participating in an EBPG development and implementation process during the pandemic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This study will provide insights into the determinants that influence the development and implementation of EBPGs during health emergencies. Its potential impact includes improving future health emergency preparedness, addressing equity gaps, and enhancing guideline development and implementation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145469532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing and Assessing Clinical Practice Guidelines and Consensus Statements for Healthy Athletes: A Scoping Review Protocol","authors":"Samyan Shahid,&nbsp;Andres Estupiñán-Bohórquez","doi":"10.1002/gin2.70050","DOIUrl":"https://doi.org/10.1002/gin2.70050","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Healthy athletes have unique physiological, psychological, and interpersonal needs that necessitate individualized prevention and management strategies. As such, this comprehensive protocol has been created to illustrate the scope, quality and coverage of these clinical practice guidelines (CPGs) and consensus statements among this specific population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods and Analysis</h3>\u0000 \u0000 <p>Searches will be conducted in PubMed, Scopus, SPORTDiscus, Web of Science, EMBASE, Google Scholar and any grey literature within official international organizations. Eligible publications will include CPGs and consensus statements that are aimed towards healthy athletes, published in English or Spanish since 2000. The AGREE II instrument will be applied to assess the quality of the guidelines by two independent reviewers. Disagreements will be resolved by a third reviewer. We will use descriptive statistics to summarize the main characteristics of the guidelines.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This scoping review seeks towards providing an in-depth analysis on the mapping, explaining, and evaluating of the available CPGs and consensus statements of the population of healthy athletes. Moreover, it will identify thematic trends, methodological strengths, and potential evidence gaps that currently exist. Fundamentally, the results will provide valuable information towards development of guidelines, standardization efforts, and evidence-based practice in the future within the field of sports medicine.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145375236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommendation Map for Type 2 Diabetes: A Protocol for a Living Systematic Review of Clinical Practice Guidelines","authors":"Qiyi Zhang,&nbsp;Shichun Wang,&nbsp;Kang An,&nbsp;Arnav Agarwal,&nbsp;Britta Tendal Jeppesen,&nbsp;Per Olav Vandvik,&nbsp;Thomas Agoritsas,&nbsp;Heath White,&nbsp;Jun Tang,&nbsp;Wanru Wang,&nbsp;Chuanfeng Tao,&nbsp;Yaolong Chen,&nbsp;Sheyu Li,&nbsp;Yinghui Jin","doi":"10.1002/gin2.70049","DOIUrl":"https://doi.org/10.1002/gin2.70049","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The global burden of type 2 diabetes, emergence of numerous new therapeutics and rapidly evolving evidence calls for trustworthy and current clinical practice guidelines (CPGs). This living systematic review of national and international CPGs aims to iteratively summarize recommendations for the management of type 2 diabetes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method and Analysis</h3>\u0000 \u0000 <p>We will search electronic databases, professional academic association websites and guideline repositories from 2010 to April 1 2024 for national, international, or professional society CPGs addressing the management of type 2 diabetes. Our initial search will be followed by quarterly literature searches. Paired reviewers will independently assess the quality of identified CPGs using AGREE-II. Recommendations and their associated methodological quality will be summarized and made available via a user-friendly interactive online platform.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This living systematic review of CPGs will enable clinicians, patients and system-level decision-makers to inform their decision-making based on internationally available CPGs. It will also allow methodologists to identify gaps in evidence and recommendations to inform future directions in research and CPGs development.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> PROSPERO Registration Number</h3>\u0000 \u0000 <p>CRD42023466448 (https://www.crd.york.ac.uk/PROSPERO/).</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145316885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Environmental Sustainability Into Evidence-Based Clinical Guidelines: Methodological Guidance Report","authors":"Kim E. van Nieuwenhuizen,&nbsp;Jeroen B. Guinée,&nbsp;Miranda W. Langendam,&nbsp;Pauline de Heer,&nbsp;Stefanie N. Hofstede,&nbsp;Frank Willem Jansen,&nbsp;Charlotte T. J. Michels,&nbsp;Dutch Expert Panel","doi":"10.1002/gin2.70046","DOIUrl":"https://doi.org/10.1002/gin2.70046","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The global healthcare sector significantly contributes to climate change and other environmental impacts. Despite this, environmental sustainability considerations are often missing from evidence-based clinical guidelines. To address this gap, we developed a methodological guidance report focused on integrating environmental sustainability into clinical guidelines.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An interdisciplinary expert panel systematically developed this methodological guidance report. Data collection involved expert panel meetings and consultations with stakeholders, based on the development of a sustainability guideline focused on reducing the environmental impact of the operating room (OR). The process included an initial inventory and prioritisation phase, guideline development following the GRADE approach, and finalisation and publication.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The generated insights offer a standardised and readily applicable guidance report for integrating environmental sustainability into clinical guidelines across medical disciplines. This allows guideline developers to implement sustainability considerations in clinical guidelines. Environmental sustainability should be addressed at the start of guideline development, involving interdisciplinary experts. Approaches include integrating environmental outcomes into the PICO framework or adding a search question focused on the environmental impact of interventions. Furthermore, environmental sustainability should be integrated in the Evidence-to-Decision framework. If LCAs are included, both the critical appraisal for study quality of LCAs and the GRADE approach for quality of the evidence are recommended.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interpretation</h3>\u0000 \u0000 <p>This methodological guidance report facilitates a stepwise approach of integrating environmental sustainability into clinical practice through evidence-based guideline development. While further evaluation and implementation in clinical practice is needed, the framework supports more sustainable clinical decision-making and contributes to promoting planetary health.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Algorithm for Incorporating Economic Evidence Into Clinical Practice Guidelines: Application to the Spanish Guideline for the Management of Chronic Primary Pain","authors":"Celia Muñoz,&nbsp;Patricia Gavín-Benavent,&nbsp;Silvia Moler-Zapata,&nbsp;Lucía Prieto Remón,&nbsp;María Bono Vega,&nbsp;Soledad Isern de Val,&nbsp;on behalf of GuíaSalud's Working Group on Incorporating Economic Evidence into CPGs","doi":"10.1002/gin2.70045","DOIUrl":"https://doi.org/10.1002/gin2.70045","url":null,"abstract":"<p>The importance of incorporating economic evidence (EE) such as resource use, cost or cost-effectiveness evidence into Clinical Practice Guidelines (CPG) is being increasingly recognised by decision makers, including healthcare providers and policy makers. Yet, this is a complex and resource-intensive process. EE can influence recommendations formulated about interventions in CPGs, especially when the desirable and undesirable effects are balanced. A group of methodologists, including health economists, in GuíaSalud (the organisation of the Spanish National Health System (NHS) that coordinates the national CPG Programme), has made important advances in the development of methodological guidance for how to develop evidence-based recommendations. In this article, we present an algorithm for informing decisions about incorporating EE in CPGs. The algorithm has three stages: (1) prioritise clinical questions in the CPG according to the influence that EE is expected to have on recommendations; (2) obtain EE for clinical questions that have been prioritised via a systematic review and/or a <i>de novo</i> economic evaluation; and (3) use EE to inform recommendations in CPG. We show how the algorithm was applied in the development of GuíaSalud's CPG for the management of chronic primary pain. In doing so, we provide specific guidance on how the algorithm could be applied using concrete examples. We show how this algorithm helps to make the process of incorporating EE into CPGs agile, dynamic and reproducible.</p>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and Facilitators of Nurses' Involvement in Guideline Development and Adaptation: A Qualitative Evidence Synthesis Protocol","authors":"Linda Velapi,&nbsp;Sara Cooper,&nbsp;Tamara Kredo,&nbsp;Bey Schmidt","doi":"10.1002/gin2.70044","DOIUrl":"https://doi.org/10.1002/gin2.70044","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Nurses often use clinical practice guidelines to assist them in treating childhood cases. Guidelines provide an easily accessible resource that clinicians can review to expand their knowledge base and determine patient care. Those involved in the guideline development and adaptation process usually have a better understanding when it comes to making use of the guideline. It is imperative to understand how the implementers of guidelines can be involved in the guideline development and adaptation process. The use of a Qualitative Evidence Synthesis is encouraged as it is the most appropriate method for this review because it enables the systematic integration of findings from primary qualitative studies that explore social, contextual, and experiential dimensions. This review seeks to answer the question: What are the views, experiences, and perceived barriers and facilitators of nurses involved in the development or adaptation of clinical practice guidelines? Using the SPIDER framework, this synthesis will focus on qualitative studies involving nurses (S), their participation in guideline development and adaptation (PI), using interviews or focus groups (D), to explore perceptions of engagement, challenges, and enabling factors (E), within a qualitative research paradigm (R).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify and synthesize studies exploring methods and processes for involving nurses in guideline development and adaptation. To explore the barriers to and facilitators of involving nurses in guideline development and adaptation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This review will follow the thematic synthesis approach and will be reported according to the ENTREQ checklist to ensure transparency in synthesis methods and the PRISMA guidelines for systematic reporting of the review process. Searches will be carried out in PubMed, CINAHL, Scopus, Medline and PsycINFO. We will apply thematic content analysis, which involves coding of extracted text, developing descriptive themes and generating analytical themes.</p>\u0000 \u0000 <p><b>Trial registration:</b> PROSPERO registration number: CRD42024580363.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correspondence on “Needs Assessment for Updating Institute of Medicine Standards for Trustworthy Clinical Practice Guidelines”","authors":"Zijun Wang,&nbsp;Hui Liu,&nbsp;Yaolong Chen","doi":"10.1002/gin2.70048","DOIUrl":"https://doi.org/10.1002/gin2.70048","url":null,"abstract":"<p>Christopher Wolfkiel and colleagues have published a valuable needs assessment for updating the IOM standards [<span>1</span>]. This study is highly necessary and leading. However, we would like to offer several comments on the study's conclusions and provide suggestions regarding key areas for updating.</p><p>Most of the above tools have attracted attention in the relevant fields and may serve as practical references for updating the IOM standards. Therefore, we strongly recommend the update of IOM standards should emphasize the integration and promotion of such mature, widely accepted tools.</p><p>Additionally, we think the urgency of the update may be overstated in the article's conclusions. While the general survey shows most respondents agree the standards “should be subject to review,” this indicates a need, but not necessarily urgency. Similarly, the domain- and item-level analysis reveals that “Hold now” was the most selected option, suggesting that many elements are still viewed as currently appropriate. To enhance clarity and reduce potential reader confusion, we suggest defining a threshold for interpreting urgency. For example, if fewer than 80% of respondents select “Hold now,” an item could be considered for update. Such an approach would help align conclusions more closely with the presented data.</p><p>We hope these comments will be helpful in guiding future updates of the IOM standards.</p><p>The authors declare no conflicts of interest.</p>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70048","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Additional Criterion to Appraisal of Guidelines for Research and Evaluation II Might Increase the Efficiency in Guideline Development for Rare Diseases: Results of a National Delphi Study","authors":"Iméze Jorieke Hieltjes,&nbsp;Charlotte M. W. Gaasterland,&nbsp;Roel Bakx,&nbsp;Silvia C. W. van Breukelen,&nbsp;Robbert J. H. Ensink,&nbsp;Charlotte van Esch,&nbsp;Raoul C. M. Hennekam,&nbsp;Ilse van Herk,&nbsp;Marieke Hermsen,&nbsp;Anja M. C. Horemans,&nbsp;Hester Rippen,&nbsp;Bart P. C. van de Warrenburg,&nbsp;Anne-Marie van Wermeskerken,&nbsp;Johanna H. van der Lee","doi":"10.1002/gin2.70040","DOIUrl":"https://doi.org/10.1002/gin2.70040","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Rare diseases significantly impact patients, and there is a need for clinical practice guidelines (CPGs) or other guidance documents as well as tools to assess their trustworthiness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The goal was to define a minimum set of criteria for the appraisal of guidance documents for rare diseases. Guidance documents include CPGs, but also other, less stringently developed documents to guide clinical practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>In 2022, we started a Delphi consensus procedure to develop criteria specifically for rare disease guidance documents. Participants were 23 delegates from 18 medical specialists' associations, 3 patient organizations for rare diseases, and 2 other medical organizations in the Netherlands. The Delphi procedure consisted of three rounds. In the first round, the participants were asked whether six prespecified criteria, selected from AGREE II, were relevant, and to add other important criteria. In the second round, all collected criteria were prioritized, and in the third round, the criteria with the highest priority were ordered by the participants. In an online meeting, the remaining criteria were reformulated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six of the seven final criteria correspond to the AGREE II criteria. The participants proposed a new criterion focusing on efficient use of limited resources, namely the inventory of problem areas as a basis for specific clinical questions to which the recommendations would provide answers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The current set of criteria for rare disease guidance documents helps evaluate the trustworthiness and enhance equitable healthcare quality for rare disease patients. Although the aim was that the minimum set of criteria reduces the time and effort for developing quality criteria for rare diseases, the participants' perceived need for methodological rigour prevailed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guidelines for Emergency Management of the Traumatic Dental Injuries of the Chilean Ministry of Health","authors":"Carlos Zaror,&nbsp;Naira F. Deana,&nbsp;Gerardo Espinoza-Espinoza,&nbsp;Pamela Burdiles,&nbsp;Carolina Mendoza,&nbsp;Paula Nahuelhual,&nbsp;Eduardo Quiñelen,&nbsp;Marie Therese Flores,&nbsp;Jaime Abarca,&nbsp;Raul Aguilera,&nbsp;Maria Alejandra Aljaro,&nbsp;Nilton Alves,&nbsp;Paola Aguilera-Ibaceta,&nbsp;Yanela Aravena,&nbsp;Francisco Araya,&nbsp;Monica Arce,&nbsp;Nadia Brocal,&nbsp;Diana Buitrago-Garcia,&nbsp;Alonso Carrasco-Labra,&nbsp;Claudia Carvajal,&nbsp;Francisco Ceballos,&nbsp;Camila Corral Nunez,&nbsp;Jaime Diaz,&nbsp;Paloma Herrera-Omegna,&nbsp;Moises Lorenzo,&nbsp;Elizabeth Lopez,&nbsp;Loreto Muñoz-Fierro,&nbsp;Patricia Muñoz-Millán,&nbsp;Ignacio Neumann Burotto,&nbsp;Paulina Nuñez,&nbsp;Patricio Parada,&nbsp;Patricia Pineda,&nbsp;Andrea Seiffert,&nbsp;Barbara Sanchez,&nbsp;Verónica Vargas,&nbsp;Bernardita Zuñiga","doi":"10.1002/gin2.70041","DOIUrl":"https://doi.org/10.1002/gin2.70041","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Traumatic dental injuries (TDIs) are the fifth most prevalent condition worldwide. Proper diagnosis and emergency management are essential for ensuring a favourable outcome and prognosis. Although other international guidelines provide recommendations for the emergency management of TDI, specific clinical situations are not always addressed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To provide the dental health team and patients with recommendations based on the best scientific evidence available for the outpatient emergency management of people suffering from TDI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The Chilean Ministry of Health formed a multidisciplinary guideline panel balanced to minimize potential bias from conflicts of interest. The Center for Research in Epidemiology, Economics and Oral Public Health (CIEESPO), Universidad de La Frontera, supported the guideline-development process, including evidence synthesis. The panel prioritized clinical questions and outcomes according to their importance for clinicians and patients. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, including GRADE Evidence-to-Decision frameworks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Recommendation</h3>\u0000 \u0000 <p>The panel agreed on 15 recommendations for outpatient management of TDIs, such as fractures, luxations and avulsions in primary and permanent dentition. Conditional recommendations for permanent teeth included performing partial pulpotomy with calcium hydroxide or bioceramic in complicated crown fractures, stabilizing with a rigid splint in cervical root fracture, performing digital repositioning and splinting in lateral and extrusive luxation for more than 48 h, performing dental reimplantation in avulsed teeth with extended extra-oral time &gt; 1 h, not treating the root surface and prescribe antibiotics in avulsed teeth. Conditional recommendations for primary teeth included performing just the extraction of the mobile fragment in complicated crown-root fractures and not splint in teeth with subluxation, lateral or extrusive luxation. Conditional recommendations for the use of mouthwash with 0.12% chlorhexidine twice a day for a period of 7–14 days in people with TDIs and against prescribing antibiotics in people with crown fracture, intra-alveolar root fracture or tooth luxation associated with trauma.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}