Clinical and Public Health Guidelines最新文献

{"title":"Mapping Evidence on Care Interventions for People Living With Motor Neurone Disease: A Protocol for a Living Evidence and Gap Map","authors":"Danielle Pollock,&nbsp;Cindy Stern,&nbsp;Melissa Bond,&nbsp;Timothy Hugh Barker,&nbsp;Sabira Hasanoff,&nbsp;Grace Holland,&nbsp;Ines Semendric,&nbsp;Anna Fragkoudi,&nbsp;Nipun Shrestha,&nbsp;Sebastian Cole Facchin-Young,&nbsp;Abigail Molly Day-Sharman,&nbsp;Lemma Negesa Bulto,&nbsp;Lara Stollery,&nbsp;Sitasma Sharma,&nbsp;Camille Schubert,&nbsp;Lynne Giles,&nbsp;Jay Beasley-Hall,&nbsp;Tracy Merlin,&nbsp;Julie Labra,&nbsp;Steve Vucic,&nbsp;Taryn Hunt,&nbsp;Zachary Munn","doi":"10.1002/gin2.70062","DOIUrl":"10.1002/gin2.70062","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To map the available evidence informing the care and management of people living with motor neurone disease (MND), including evidence pertaining to carers, asymptomatic genetic carriers, family, friends and healthcare professionals caring for people with MND.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>MND is a devasting neurodegenerative disease that has no cure and eventually leads to paralysis, progressive speech difficulties and respiratory failure. There are a plethora of interventions to support people living with MND, however, information regarding these interventions is often not organised in a manner that best supports the MND community. An evidence and gap map will provide a visual presentation that highlights the existing evidence that is available to support specific interventions, and indicate where there is no evidence. This will help inform future guideline and research efforts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Inclusion Criteria</h3>\u0000 \u0000 <p>Studies if they describe care interventions for people living with MND, carers, asymptomatic genetic carriers, family, friends and healthcare professionals caring for people with MND. Peer-reviewed randomised controlled trials, and nonrandomised studies of interventions, systematic reviews and qualitative studies describing the experience of an intervention will be included.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An evidence and gap map will be conducted according to Campbell guidance and JBI guidance for scoping reviews. A comprehensive search of academic databases and clinical trial registries will be performed to identify eligible studies. An evidence inclusion framework has been developed with members of the MND community. Data screening and extraction will be independently performed by two reviewers. The evidence and gap map will be presented using EPPI Reviewer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Review Registration</h3>\u0000 \u0000 <p>This protocol has been uploaded to the Australian Motor Neurone Disease (MND) Guideline Open Science Framework page (https://osf.io/c2ezm/).</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146135796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incorporating Antimicrobial Resistance Considerations in Antimicrobial Evidence-Based Practice Guidelines: A Protocol for the Development of a Checklist and Multifaceted Appraisal of Existing Guidelines","authors":"Sara Ibrahim,&nbsp;Mark Loeb,&nbsp;Jessica Bartoszko,&nbsp;Maryam Ghadimi,&nbsp;Gordon Guyatt,&nbsp;Benedikt Huttner,&nbsp;Alfonso Iorio,&nbsp;Dominik Mertz,&nbsp;Lorenzo Moja,&nbsp;Gabriel Rada,&nbsp;Pilar Ramon-Pardo,&nbsp;Ludovic Reveiz,&nbsp;Gerard Wright,&nbsp;Nancy Santesso,&nbsp;Romina Brignardello-Petersen","doi":"10.1002/gin2.70057","DOIUrl":"10.1002/gin2.70057","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Antimicrobial resistance (AMR) is a widely recognized threat to global health, mainly driven by the inappropriate use of antimicrobials. Recommendations from evidence-based practice guidelines (EBPGs) can promote appropriate antimicrobial use. Currently, no guidance exists for considering AMR in EBPGs. This is the protocol for two studies that aim to (1) develop a checklist of AMR considerations for EBPGs and (2) conduct a case study to evaluate existing EBPGs regarding the extent to which AMR is considered among other methodological assessments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the Delphi technique, we will consult with individuals from four interest-holder groups to develop and refine a checklist of AMR considerations for EBPGs. To assess EBPGs, we will search various databases for guidelines on four prioritized syndromes (i.e., community-acquired pneumonia, urinary tract infection, skin and soft tissue infections and exacerbations of chronic obstructive pulmonary disease). We will screen articles in duplicate and in stages to include EBPGs for the prioritized syndromes and will use piloted data extraction forms to extract characteristics of the EBPGs. For each EBPG, we will evaluate whether AMR was considered (using the developed checklist), its trustworthiness (i.e., methodological quality) (using the modified National Guideline Clearinghouse Extent of Adherence to Trustworthy Standards instrument) and its adaptability (using items from existing adaptability frameworks).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This work will develop a checklist of AMR considerations for EBPGs and evaluate a subsequent sample of EBPGs to investigate the extent to which AMR is considered. Furthermore, by conducting a methodological appraisal of trustworthiness and adaptability, this study will contextualize results to promote the uptake and appropriate interpretation of existing guidelines. Thus, these findings will be useful to decision-makers as well as guideline development groups as they highlight what existing work can be trusted and leveraged while also identifying what limitations and gaps need to be addressed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146136830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Knowledge Translation Strategies for Guideline Implementation: Protocol for an Update of an Overview of Systematic Reviews","authors":"Kian Torabiardakani,&nbsp;Shraddha Sawant,&nbsp;Gonzalo Bravo-Soto,&nbsp;Daniela Montalva-Romero,&nbsp;Rachel J. Couban,&nbsp;Abigail E. Chu,&nbsp;Norman Buckley,&nbsp;Gordon Guyatt,&nbsp;David Juurlink,&nbsp;Jason W. Busse,&nbsp;Andrea J. Darzi","doi":"10.1002/gin2.70058","DOIUrl":"https://doi.org/10.1002/gin2.70058","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Healthcare guidelines are necessary to optimise patient care and improve health outcomes; however, guidelines alone are insufficient to ensure changes in practice. This overview of reviews aims to identify, map and report on the effectiveness of knowledge translation (KT) strategies to implement guideline recommendations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We will conduct this study in accordance with the Cochrane Handbook guidance on overviews of reviews. We will search MEDLINE, CRD, SCOPUS, Cochrane Library, Web of Science, Health Systems Evidence, Epistemonikos, CINAHL and Embase. Eligible studies will include systematic reviews evaluating KT interventions for guideline implementation, regardless of the healthcare condition or system level. Teams of reviewers will independently screen and extract data on systematic review characteristics, interventions, outcomes (process-, healthcare professional-, patient- and economic-related and other), contextual factors and review limitations. The same reviewers will assess risk of bias among included reviews using A MeaSurement Tool to Assess Systematic Reviews 2 (AMSTAR 2). We will synthesise the evidence by classifying intervention effectiveness into the following categories: (1) desirable effect, (2) little or no effect, (3) undesirable effect and (4) uncertain effect, along with the certainty of evidence, if reported. We will present our findings through a narrative synthesis, tabular formats, and an evidence gap map to visualise the evidence landscape.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This overview of reviews will provide a summary of KT strategies and their effectiveness for improving guideline implementation. These findings will offer actionable guidance for key interest-holders: investigators can utilise the evidence gap map to identify research priorities; guideline developers can identify effective strategies for increasing uptake of recommendations; and funders can optimise resource allocation by directing support towards evidence-based dissemination strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146136838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a GIN-McMaster Checklist Extension for Out-of-Hospital Health Guidelines: A Research Protocol","authors":"Brendan V. Schultz,&nbsp;Timothy H. Barker,&nbsp;Emma Bosley,&nbsp;Amy Keir,&nbsp;Christian Martin-Gill,&nbsp;Dannielle Pollock,&nbsp;Eddy Lang,&nbsp;Elie A. Akl,&nbsp;Holger J. Schünemann,&nbsp;Jennifer Petkovic,&nbsp;Joanne Khabsa,&nbsp;Louise Reynolds,&nbsp;Michael McCaul,&nbsp;Michelle Thomson,&nbsp;Miloslav Klugar,&nbsp;Paul Simpson,&nbsp;Robin Pap,&nbsp;Sonja Maria,&nbsp;Wojtek Wiercioch,&nbsp;Zachary Munn","doi":"10.1002/gin2.70060","DOIUrl":"10.1002/gin2.70060","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The delivery of healthcare in the out-of-hospital setting by paramedics, emergency medical technicians, and first responders is informed by various health guidelines that cover a myriad of medical presentations. These guidelines often score poorly on quality assessment tools and do not routinely meet accepted standards for guideline development. To address this, we propose the development of an extension to the Guideline International Network (GIN)-McMaster Guideline Development Checklist (GDC) to assist developers of health guidelines on out-of-hospital care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The aim of this project are to: (i) identify the current methodologies, approaches and processes used by developers of guidelines on out-of-hospital care and determine how they align with the original GIN-McMaster GDC; (ii) understand the overarching barriers and enablers of guideline development in this setting; (iii) generate a fit-for-purpose extension through an iterative consensus-based approach; and (iv) disseminate this document to target users.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This protocol outlines the proposed development of an extension to the GIN-McMaster GDC, designed specifically for developers of health guidelines on out-of-hospital care. The development of this extension will be informed by understanding current practices and the determinants that influence guideline development in this setting. This will involve reviewing all items within the original checklist to determine if modifications and/or new items are required.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70060","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146136837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Knowledge Translation Strategies for Guideline Implementation: Protocol for an Update of an Overview of Systematic Reviews","authors":"Kian Torabiardakani,&nbsp;Shraddha Sawant,&nbsp;Gonzalo Bravo-Soto,&nbsp;Daniela Montalva-Romero,&nbsp;Rachel J. Couban,&nbsp;Abigail E. Chu,&nbsp;Norman Buckley,&nbsp;Gordon Guyatt,&nbsp;David Juurlink,&nbsp;Jason W. Busse,&nbsp;Andrea J. Darzi","doi":"10.1002/gin2.70058","DOIUrl":"10.1002/gin2.70058","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Healthcare guidelines are necessary to optimise patient care and improve health outcomes; however, guidelines alone are insufficient to ensure changes in practice. This overview of reviews aims to identify, map and report on the effectiveness of knowledge translation (KT) strategies to implement guideline recommendations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We will conduct this study in accordance with the Cochrane Handbook guidance on overviews of reviews. We will search MEDLINE, CRD, SCOPUS, Cochrane Library, Web of Science, Health Systems Evidence, Epistemonikos, CINAHL and Embase. Eligible studies will include systematic reviews evaluating KT interventions for guideline implementation, regardless of the healthcare condition or system level. Teams of reviewers will independently screen and extract data on systematic review characteristics, interventions, outcomes (process-, healthcare professional-, patient- and economic-related and other), contextual factors and review limitations. The same reviewers will assess risk of bias among included reviews using A MeaSurement Tool to Assess Systematic Reviews 2 (AMSTAR 2). We will synthesise the evidence by classifying intervention effectiveness into the following categories: (1) desirable effect, (2) little or no effect, (3) undesirable effect and (4) uncertain effect, along with the certainty of evidence, if reported. We will present our findings through a narrative synthesis, tabular formats, and an evidence gap map to visualise the evidence landscape.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This overview of reviews will provide a summary of KT strategies and their effectiveness for improving guideline implementation. These findings will offer actionable guidance for key interest-holders: investigators can utilise the evidence gap map to identify research priorities; guideline developers can identify effective strategies for increasing uptake of recommendations; and funders can optimise resource allocation by directing support towards evidence-based dissemination strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146136836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Webinars to Impact: Reenvisioning Clinical Guideline Ecosystem in Africa","authors":"Akah Thelma Eni,&nbsp;Ernest Alang Wung,&nbsp;Awah Noella,&nbsp;Ngeh Etienne,&nbsp;Karen DiValerio Gibbs,&nbsp;Guideline International Network- Africa Regional Community,&nbsp;Ebunoluwa Ayinmode","doi":"10.1002/gin2.70059","DOIUrl":"https://doi.org/10.1002/gin2.70059","url":null,"abstract":"&lt;p&gt;Guidelines are like a compass for putting evidence into practice in global health. They serve as a blueprint for quality care, decision-making guidelines, and, when executed correctly, a lifeline for equitable health outcomes [&lt;span&gt;1&lt;/span&gt;]. However, across low and middle-income countries (LMICS), particularly Africa, it is challenging to transition from developing guidelines to implementing them [&lt;span&gt;2&lt;/span&gt;]. Imported guidelines often overlook the nuanced details of local context [&lt;span&gt;3&lt;/span&gt;], and systemic barriers, such as limited capacity and weak infrastructure, hinder their implementation. Against this backdrop, the Guidelines International Network (GIN) Africa regional community launched a daring initiative: could a simple webinar series spark a paradigm shift on how guidelines are developed, shared, and implemented across the continent [&lt;span&gt;4&lt;/span&gt;]? The outcome was not merely affirmative but sparked scholarly reflections.&lt;/p&gt;&lt;p&gt;Between 2024 and 2025, GIN Africa hosted a series of webinars that went beyond the traditional ‘talkshop’ model. While individual presentations provided context and case examples, the ideas in this editorial reflect recurring themes that emerged across the discussions, regardless of the speaker or specific topic. These sessions became living repositories where new ideas like the Practical Approach to Care Kit (PACK) [&lt;span&gt;5&lt;/span&gt;] and AI-powered tools like AISHA have shown how locally designed, scalable solutions can transform the way clinical guidelines come to life. However, this movement encompasses more than just digital tools and frameworks. Rethinking guideline use begins with inclusivity, context, and local ownership. This editorial invites scholarly and professional reflection on how webinars shape knowledge, behavior, and guideline practices in LMICS. Four consistent priorities emerged from the discussions: building capacity, strengthening partnerships, using innovation wisely, and broadening engagement in guidelines.&lt;/p&gt;&lt;p&gt;Effective guideline development cannot happen in isolation. It depends on strong cross-regional/transnational partnerships that enable knowledge exchange, alignment of experiences, and the creation of recommendations that are both globally robust and locally relevant. Such partnerships foster resource sharing, build capacity, and harmonize standards, factors that improve the adoption of guidelines across diverse settings. Also, transnational collaboration encourages cross-system learning, while cross-disciplinary engagement ensures recommendations are both evidence-based and practical. Equally important is cross-sectoral involvement, bringing together government, civil society, the private sector, and communities. This broad participation enhances credibility, strengthens relevance, and builds shared ownership, all of which support sustainable implementation.&lt;/p&gt;&lt;p&gt;Capacity building is especially critical in LMICs, where resources are often limited. Initiatives such as","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146007717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Planetary Health in Health Guidelines and Health Technology Assessments: A Scoping Review","authors":"Pakeezah Saadat,&nbsp;Maheen Raja,&nbsp;Andrea J. Darzi,&nbsp;Charlotte T. J. Michels,&nbsp;Alina Herrmann,&nbsp;Karolina Anna Scahill,&nbsp;Laura M. Jewell,&nbsp;K. M. Saif-Ur-Rahman,&nbsp;Hendrik Napierala,&nbsp;Ruben Heuer,&nbsp;Rebecca L. Morgan,&nbsp;Grigorios I. Leontiadis,&nbsp;Ignacio Neumann,&nbsp;Fiona A. Miller,&nbsp;Holger J. Schünemann,&nbsp;Thomas Piggott","doi":"10.1002/gin2.70056","DOIUrl":"https://doi.org/10.1002/gin2.70056","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Individual human health is inextricably linked to planetary health, which refers to the health of human civilization and the natural systems on which it depends. These systems are captured by the nine planetary boundaries which together define a safe operating space for humanity. The health sector contributes to the transgression of these boundaries, thereby jeopardizing both individual and planetary health. However, there is a growing interest in the health sector in incorporating the preservation of planetary boundaries into health guidelines and health technology assessments (HTAs), which synthesize evidence and guide healthcare decisions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This scoping review aims to describe methodological guidance and considerations for incorporating planetary health in health guidelines and HTAs. We conducted a scoping review adhering to the JBI methodology including articles from several databases since inception until September 2023. We used narrative synthesis and descriptive statistics to describe eligible studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 38 included studies, 14 (37%) were commentaries, six (16%) were methodological papers, and four (10·5%) were health guidelines. Included studies focused primarily on greenhouse gas emissions as an outcome. The included health guidelines were rated at a median of 52% (range: 16% to 67%) on AGREE II for methodological quality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Key findings pertain to the normative significance of planetary health in guidelines and HTAs, scope and quality of included studies, inconsistencies in methods, and challenges in implementation. These findings will inform future Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) guidance on planetary health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Registration</h3>\u0000 \u0000 <p>A protocol of this scoping review was registered in Open Science Framework (https://osf.io/3jmsa) and published in the journal Systematic Reviews (10.1186/s13643-024-02577-2).</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145739895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol for the Development of The Australian Motor Neurone Disease (MND) Guideline","authors":"Cindy Stern,&nbsp;Danielle Pollock,&nbsp;Timothy Barker,&nbsp;Grace McKenzie Holland,&nbsp;Sabira Hasanoff,&nbsp;Nipun Shrestha,&nbsp;Ines Semendric,&nbsp;Lemma Negesa Bulto,&nbsp;Sitasma Sharma,&nbsp;Anna Fragkoudi,&nbsp;Sebastian Cole Facchin-Young,&nbsp;Abigail Molly Day-Sharman,&nbsp;Lara Stollery,&nbsp;Jay Beasley-Hall,&nbsp;Camille Schubert,&nbsp;Lynne Giles,&nbsp;Tracy Merlin,&nbsp;Steve Vucic,&nbsp;Jo Whitehouse,&nbsp;Zachary Munn","doi":"10.1002/gin2.70055","DOIUrl":"https://doi.org/10.1002/gin2.70055","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Motor neurone disease (MND) is a rare but devastating neurodegenerative condition that results in progressive muscle weakness, disability, and eventual respiratory failure. In Australia, the impact of MND is significant, and there is a pressing need for a high-quality, locally relevant guideline to support equitable, person-centred care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Questions</h3>\u0000 \u0000 <p>This guideline aims to address key clinical and care-related questions that arise across the MND trajectory. It will identify the most pressing topics and uncertainties in MND management through interest holder consultation and structured prioritisation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The guideline will be developed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach and will align with standards set by the National Health and Medical Research Council (NHMRC) and the Guidelines International Network (GIN). Governance will include a multi-tiered structure with lived experience representation. Implementation planning and evaluation will be integrated throughout, with a planned transition to a living guideline model supported by an ongoing evidence surveillance strategy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145750905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best Practice Guideline Development Methods: An Integrated Approach Based on the Registered Nurses' Association of Ontario's Methods","authors":"Lyndsay Howitt,&nbsp;Amy Burt,&nbsp;Nafsin Nizum,&nbsp;Christine Buchanan,&nbsp;Michelle Rey,&nbsp;Doris Grinspun","doi":"10.1002/gin2.70052","DOIUrl":"https://doi.org/10.1002/gin2.70052","url":null,"abstract":"<p>Since 1999, the Registered Nurses' Association of Ontario (RNAO) has developed best practice guidelines (BPG) to promote consistency and quality of evidence-based care and improve patient, organization and health system outcomes. A distinguishing feature of RNAO's BPG development portfolio is its integration within RNAO's three-pillar BPG programme. This programme supports health service and academic organizations, Best Practice Spotlight Organizations® (BPSO®), to systematically implement, monitor and evaluate BPGs. Through formal partnerships with these organizations, the BPSO network extends the reach of the BPG programme and provides RNAO with direct feedback from end users, strengthening the relevance of future guideline editions. This article describes RNAO's integrated BPG development methods, outlining how evidence-based recommendations are made to support organizations implementing BPGs. Following extensive pre-development work to shape the purpose and scope of each guideline, an interprofessional expert panel that includes people with lived experience is appointed. Using the Grading of Recommendations, Assessment, Development and Evaluation methods, the expert panel prioritizes research questions and systematic reviews are conducted to determine strong or conditional recommendations. Good practice statements are also included and resources to support guideline implementation and evaluation are formulated including fact sheets, RNAO Clinical Pathways™ and evaluation measures. Draft guidelines undergo external review to ensure relevance and usability. To best serve the needs of organizations implementing BPGs, ongoing efforts are being made to keep RNAO's methods up-to-date and incorporate evaluation data from implementing organizations into the guideline development process.</p>","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70052","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145619328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Putting People at the Centre of Guidelines","authors":"Karen Graham,&nbsp;Naomi Fearns","doi":"10.1002/gin2.70054","DOIUrl":"https://doi.org/10.1002/gin2.70054","url":null,"abstract":"&lt;p&gt;In our 30 years of producing guidelines, the Scottish Intercollegiate Guidelines Network (SIGN) has consistently adhered to the principles of Appraisal of Guidelines for Research and Evaluation (AGREE II) [&lt;span&gt;1&lt;/span&gt;], prioritising Patient and Public Involvement (PPI) as set out in our SIGN 50 methodology handbook [&lt;span&gt;2&lt;/span&gt;]. This commitment to PPI helps SIGN to produce high-quality clinical guidelines, that foster shared decision-making by recognising the outcomes that are important to people with lived experience, their values and their preferences [&lt;span&gt;3-8&lt;/span&gt;]. Despite its value in guideline development, we recognise that more evaluation and research is needed to provide evidence of the impact of PPI on guideline quality, acceptability, implementation success and health outcomes [&lt;span&gt;9, 10&lt;/span&gt;]. SIGN works in partnership with professionals, the third sector (non-profit organisations and charities), people with lived experience and the public, which enhances our guidelines credibility and helps us to tailor them to meet the real-world needs of all interest-holders [&lt;span&gt;5-8, 11, 12&lt;/span&gt;]. In summary, PPI helps to make guideline recommendations better by incorporating patient preferences and values into them, and this helps guideline developers to achieve their aim of enhancing patient care and improving health outcomes [&lt;span&gt;3, 11-14&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;In this commentary we showcase the significance of PPI in the development of clinical guidelines by SIGN, using its dementia guideline [&lt;span&gt;15&lt;/span&gt;], as a case example. We provide insights into SIGN's collaborative efforts, reinforcing the importance of diverse perspectives at each stage of the guideline development process.&lt;/p&gt;&lt;p&gt;The SIGN guideline on Assessment, diagnosis, care and support for people with dementia and their carers was published in 2023 [&lt;span&gt;15&lt;/span&gt;]. It encourages all health and social care professionals to adopt person-centred care and treat people living with dementia and unpaid carers as individuals. The methodology we used for developing this guideline is outlined in SIGN 50 [&lt;span&gt;2&lt;/span&gt;]. The quotes used to illustrate the commentary are drawn from feedback provided from carers and third sector organisation representatives gathered through surveys conducted during development of the guideline.&lt;/p&gt;&lt;p&gt;Representatives from third sector organisations and carers of people with dementia were members of our guideline development group and worked in partnership with professionals to produce the guideline. Carers played a crucial role in ensuring that issues that they saw as priorities, such as anticipatory grief, were thoroughly considered and addressed.&lt;/p&gt;&lt;p&gt;Third sector organisations invited people with dementia and their carers to participate in our guideline development processes to ensure diverse perspectives influenced decisions. We held multiple sessions with people with dementia, to ensure their perspectives were integrated into the wordi","PeriodicalId":100266,"journal":{"name":"Clinical and Public Health Guidelines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gin2.70054","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145521883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}