Boletín Médico Del Hospital Infantil de México (English Edition)最新文献_第5页

Cultural order, disease and health care 文化秩序、疾病和保健

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m17000011

L. Viniegra-Velázquez

引用次数: 0

Autoimmune hepatitis in the pediatric age 儿童期自身免疫性肝炎

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2019-01-01 DOI: 10.24875/bmhime.m17000002

R. Peña-Vélez, Enory Almanza-Miranda

引用次数: 0

Disseminated aspergillosis due to Aspergillus flavus in a pediatric patient with a recent diagnosis of acute lymphoblastic leukemia 最近诊断为急性淋巴细胞白血病的儿童患者的黄曲霉引起的播散性曲霉病

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-18 DOI: 10.24875/BMHIME.M17000008

M. Avilés-Robles, F. O. Mendoza-Camargo, Bertha Lilia Romero-Baizabal, C. Serrano-Bello, F. Ortega-Ríosvelasco

{"title":"Disseminated aspergillosis due to Aspergillus flavus in a pediatric patient with a recent diagnosis of acute lymphoblastic leukemia","authors":"M. Avilés-Robles, F. O. Mendoza-Camargo, Bertha Lilia Romero-Baizabal, C. Serrano-Bello, F. Ortega-Ríosvelasco","doi":"10.24875/BMHIME.M17000008","DOIUrl":"https://doi.org/10.24875/BMHIME.M17000008","url":null,"abstract":"Twenty-nine-year-old mother, primary school education, cleaning assistant, single, denied drug use. Father outside de family nucleus, medical history unknown. A nine-year-old brother, healthy. Two half-brothers on the mother’s side of 6 and 12 years of age, healthy. Resident of Tultitlán, State of Mexico. He lived in a house with five rooms with running water, electricity and drainage system, with 20 cohabitants. He was exposed to lamb, chickens, cats, a dog, and a rabbit. His diet consisted of four meals a day, with a high intake of simple carbohydrates. Psychomotor development according to age. He attended the third grade and had good academic performance. Immunizations: the fourth dose of the pentavalent vaccine and the first and second doses of the triple viral vaccine were missed. Product of the third pregnancy. Irregular prenatal control from the second trimester. The mother began with hematinics since the second trimester. She attended five consultations, and four obstetric ultrasounds were performed (OUS) which were referred as normal. She had repeated episodes of cervicovaginitis from the second trimester, without any treatment. The product was delivered vaginally at 42 weeks of gestation (WOG). He breathed and cried at birth. Apgar 8/9, Capurro 42 WOG, a weight of 2700 g, and 47 cm of height. Advanced resuscitation maneuvers were not required. Both were discharged after 24 hours without any complications. Allergies, previous surgical history, traumatisms, transfusions and previous hospitalizations were denied.","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"323 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78304461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characterization and antimicrobial resistance of Escherichia coli in pediatric patients with urinary tract infection at a third level hospital of Quito, Ecuador 厄瓜多尔基多某三级医院尿路感染患儿大肠杆菌临床特征及耐药性分析

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-01 DOI: 10.1016/j.bmhime.2017.02.002

引用次数: 0

Epigenetic alterations in acute lymphoblastic leukemia 急性淋巴细胞白血病的表观遗传改变

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-01 DOI: 10.1016/j.bmhime.2018.01.004

María del Pilar Navarrete-Meneses, Patricia Pérez-Vera

{"title":"Epigenetic alterations in acute lymphoblastic leukemia","authors":"María del Pilar Navarrete-Meneses, Patricia Pérez-Vera","doi":"10.1016/j.bmhime.2018.01.004","DOIUrl":"10.1016/j.bmhime.2018.01.004","url":null,"abstract":"<div><p>Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. It is well-known that genetic alterations constitute the basis for the etiology of ALL. However, genetic abnormalities are not enough for the complete development of the disease, and additional alterations such as epigenetic modifications are required. Such alterations, like DNA methylation, histone modifications, and noncoding RNA regulation have been identified in ALL. DNA hypermethylation in promoter regions is one of the most frequent epigenetic modifications observed in ALL. This modification frequently leads to gene silencing in tumor suppressor genes, and in consequence, contributes to leukemogenesis. Alterations in histone remodeling proteins have also been detected in ALL, such as the overexpression of histone deacetylases enzymes, and alteration of acetyltransferases and methyltransferases. ALL also shows alteration in the expression of miRNAs, and in consequence, the modification in the expression of their target genes. All of these epigenetic modifications are key events in the malignant transformation since they lead to the deregulation of oncogenes as <em>BLK, WNT5B</em> and <em>WISP1</em>, and tumor suppressors such as <em>FHIT, CDKN2A, CDKN2B</em>, and <em>TP53</em>, which alter fundamental cellular processes and potentially lead to the development of ALL. Both genetic and epigenetic alterations contribute to the development and evolution of ALL.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 4","pages":"Pages 243-264"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2018.01.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54312407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Acrodermatitis enteropathica 肢皮炎enteropathica

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-01 DOI: 10.1016/j.bmhime.2018.01.001

María Elena Martínez-Bustamante , Rubén Peña-Vélez , Enory Almanza-Miranda , Carlos Andrés Aceves-Barrios , Tonatiuh Vargas-Pastrana , Alfredo Raúl Rodolfo Morayta-Ramírez Corona

{"title":"Acrodermatitis enteropathica","authors":"María Elena Martínez-Bustamante , Rubén Peña-Vélez , Enory Almanza-Miranda , Carlos Andrés Aceves-Barrios , Tonatiuh Vargas-Pastrana , Alfredo Raúl Rodolfo Morayta-Ramírez Corona","doi":"10.1016/j.bmhime.2018.01.001","DOIUrl":"10.1016/j.bmhime.2018.01.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Acrodermatitis enteropathica is a low-incidence disease due to inherited or acquired zinc deficiency. It is characterized by acral dermatitis, alopecia, diarrhea and growth retardation. The dermatological condition may mimic a cutaneous fungal infection or other pathogen-related skin diseases.</p></div><div><h3>Case report</h3><p>We report the case of a female patient of 7 months of age, who was sent to <em>Centro Médico Nacional 20 de Noviembre</em> for suspicion of immunodeficiency and cutaneous mycosis. Her condition began with dermatosis disseminated to the head, trunk and genital region; initial treatment with antifungal and broad spectrum antibiotics was given, without improvement. Upon admission, immunodeficiency and fungal infection were discarded. Acrodermatitis enteropathica was suspected, and corroborated later by low serum zinc levels. Immediately after the start of oral treatment with zinc, the patient showed improvement.</p></div><div><h3>Conclusions</h3><p>There are multiple differential diagnoses of acrodermatitis enteropathica, which includes cutaneous infections. Therefore, the early recognition of the characteristic lesions favors suspicion, diagnosis and appropriate treatment.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 4","pages":"Pages 295-300"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2018.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54312400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary tract infection: a prevalent problem in pediatrics 尿路感染:儿科的一个普遍问题

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-01 DOI: 10.1016/j.bmhime.2018.01.005

Consuelo Restrepo de Rovetto

引用次数: 1

Risk factors associated with complications that required the removal of peripherally inserted central venous catheters in a tertiary pediatric hospital 在一家三级儿科医院，与需要切除外周中心静脉导管的并发症相关的危险因素

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-01 DOI: 10.1016/j.bmhime.2017.03.003

Miriam Flores Moreno , Karina Saray Pueblas Bedoy , Aurelia Ojeda Sánchez , Nallely Zurita-Cruz

{"title":"Risk factors associated with complications that required the removal of peripherally inserted central venous catheters in a tertiary pediatric hospital","authors":"Miriam Flores Moreno , Karina Saray Pueblas Bedoy , Aurelia Ojeda Sánchez , Nallely Zurita-Cruz","doi":"10.1016/j.bmhime.2017.03.003","DOIUrl":"https://doi.org/10.1016/j.bmhime.2017.03.003","url":null,"abstract":"<div><h3>Background</h3><p>In pediatrics, complications of the peripherally inserted central venous catheters (PICC) are reported in 30-40% of the cases, being the age of the patient and the location of PICC the most frequent risk factors. This study aimed to describe the characteristics of PICCs and to identify factors related to their withdrawal due to complications.</p></div><div><h3>Methods</h3><p>A prospective cohort study was conducted. Patients from 2 months to 18 years of age were included and followed-up until PICC was withdrawn. Age, sex, medications administered, PICC location, caliber, the number of lumens, days PICC was on the patient, and the reason for withdrawal was recorded. Univariate and multivariate analyses were performed.</p></div><div><h3>Results</h3><p>Two hundred and twenty-five patients were included. In 33.02%, PICC was withdrawn due to complications. In the bivariate analysis, age and location were factors associated with complications. A Cox proportional hazards model was performed. Only the caliber thickness (hazard ratio (HR): 0.5, confidence interval (CI) 95%: 0.35-0.99) was associated with any complication, and age (HR: 1.02, CI95%: 1-1.04) to the withdrawal of PICC due to suspected phlebitis.</p></div><div><h3>Conclusions</h3><p>PICC withdrawal due to complications was performed in 33% of the patients. Risk factors related to complications were PICC caliber thickness and age.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 4","pages":"Pages 289-294"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137281445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Education in our time: competency or aptitude? The case for medicine. Part II 我们这个时代的教育:能力还是天赋?用药的理由。第二部分

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-01 DOI: 10.1016/j.bmhime.2016.08.002

Leonardo Viniegra-Velázquez

{"title":"Education in our time: competency or aptitude? The case for medicine. Part II","authors":"Leonardo Viniegra-Velázquez","doi":"10.1016/j.bmhime.2016.08.002","DOIUrl":"https://doi.org/10.1016/j.bmhime.2016.08.002","url":null,"abstract":"<div><p>Part II is focused on participatory education (PE), a distinctive way to understand and practice education in contrast to passive education. The core of PE is to develop everyone's cognitive potential, which is frequently neglected or ignored.</p><p>The epistemological and empirical basis of PE is defined as the concept of <em>creative critique</em>, the idea of knowledge as each person's construction and life experience as the focus of reflection and cognition. PE aims towards educating individuals with unprecedented cognitive and creative capabilities, qualified to approach a more inclusive and hospitable world.</p><p>The last part is about the fact that medical education has remained among the passive education paradigm of the <em>professional capabilities</em>. It emphasizes the critical role of <em>cognitive skills</em>, both methodological and practical (clinical aptitude), in the progress of medical education and practice. Finally, it discusses what to do and how to do all these elements, aiming towards a better world away from human degradation.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 4","pages":"Pages 309-317"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2016.08.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137280859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Congenital malformations at birth: Mexico, 2008-2013 出生时的先天性畸形:墨西哥，2008-2013

Boletín Médico Del Hospital Infantil de México (English Edition) Pub Date : 2017-07-01 DOI: 10.1016/j.bmhime.2018.01.002

Eduardo Navarrete-Hernández , Sonia Canún-Serrano , Javier Valdés-Hernández , Aldelmo Eloy Reyes-Pablo

引用次数: 1