Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects最新文献

筛选
英文 中文
The fate of cholesteryl esters in human serum incubated in vitro at 38° 38°体外培养人血清中胆固醇酯的命运
Carl S. Rehnborg, Alex V. Nichols
{"title":"The fate of cholesteryl esters in human serum incubated in vitro at 38°","authors":"Carl S. Rehnborg,&nbsp;Alex V. Nichols","doi":"10.1016/0926-6542(64)90129-5","DOIUrl":"10.1016/0926-6542(64)90129-5","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Following the incubation of nonlipemic human serum (serum glyceride concentration, 49 mg%) at 38° for 36 h, the major lipoprotein species (S<sub><em>f</em></sub> 20-10<sup>5</sup>, S<sub><em>f</em></sub> 0–20, high-density lipoproteins) have been isolated ultracentrifugally and their lipid compositions determined. In all three lipoprotein species, the molar concentrations of cholesterol and phospholipids decrease, while those of the cholesteryl esters increase. The data indicate that during the course of the incubation some of the cholesteryl esters are released from the S<sub><em>f</em></sub> 0–20 lipoproteins and, subsequently, are associated with the S<sub><em>f</em></sub> 20-10<sup>5</sup> lipoproteins and the high-density lipoproteins.</p></span></li><li><span>2.</span><span><p>2. Although the total glyceride content in the serum remains constant, it decrease in the S<sub><em>f</em></sub> 20-10<sup>5</sup> lipoproteins and increases in the high-density lipoproteins and the S<sub><em>f</em></sub> 0–20 lipoproteins. The observed reduction in the S<sub><em>f</em></sub> 20-10<sup>5</sup> lipoprotein is attributed to the transfer of glyceride to the other lipoproteins during incubation.</p></span></li><li><span>3.</span><span><p>3. The fatty acid distributions to the glyceride and cholesteryl ester fractions have been determined by gas-chromatographic techniques. Significant changes are observed only in the glyceride fatty acids of the S<sub><em>f</em></sub> 20-10<sup>5</sup> lopoproteins.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 596-603"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90129-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23806301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 55
Les phospholipides de la cellule hépatique. Interprétation fonctionnelle de leur renouvellement 肝细胞的磷脂。对其更新的功能解释
Marc Pascaud
{"title":"Les phospholipides de la cellule hépatique. Interprétation fonctionnelle de leur renouvellement","authors":"Marc Pascaud","doi":"10.1016/0926-6542(64)90123-4","DOIUrl":"10.1016/0926-6542(64)90123-4","url":null,"abstract":"<div><p>Study at the subcellular level of the renewal of the hepatic phospholipid fatty acids by the endogenous fatty acids shows particularly the activity of the free fat phsophoglycerides. The fact that the incorporation intensities, the fastest for palmitic acid (half-life about 3 h), are similar, is in accordance with rapid intracellular exchanges.</p><p>The renewal of only the fatty acids in the phosphoglycerid molecule satisfies a function of intracellular transfer of fatty acids. The slower renewal of the intact molecule, joined to the renewal of the proteins, suggests a mechanism of disintegration and rebuilding of the membranes (endoplasmic reticulum and mitochondria) which leads to equilibrium of the cellular lipoproteins and permits entrance to the metabolites.</p></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 528-537"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90123-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74481008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Periodate oxidation studies of human brain gangliosides 人脑神经节苷脂的高碘酸盐氧化研究
G.A. Johnson , R.H. McCluer
{"title":"Periodate oxidation studies of human brain gangliosides","authors":"G.A. Johnson ,&nbsp;R.H. McCluer","doi":"10.1016/0926-6542(64)90128-3","DOIUrl":"10.1016/0926-6542(64)90128-3","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Four chromatographically homogenous gangliosides (FM, 1-G, 3-G, 4-G) and the ceramide-tetrose (asialoganglioside) were isolated and subjected to periodate oxidation.</p></span></li><li><span>2.</span><span><p>2. Periodate reduction was quantitatively determined with the mon-, di-, and trisialoganglioside (1-G, 3-G, 4-G) preparations.</p></span></li><li><span>3.</span><span><p>3. The periodate-resistant carbohydrate residues were determined in all five preparations.</p></span></li><li><span>4.</span><span><p>4. The results are consistent with the structure monosialoganglioside proposed by <span>Kuhn and Wiegandt</span>.</p></span></li><li><span>5.</span><span><p>5. The disialo- and trisialongangliosides (3-G and 4-G) isolated contained a sialic acid residue resistant to periodate oxiation. Ganglioside 4-G is apparently a previously unreported trisialogangliosides, since one of the galactose residues was subject to periodate oxidation.</p></span></li><li><span>6.</span><span><p>6. Structures for the ganglioside preparations are proposed.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 587-595"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90128-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23799446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Studies of incorporation of radioactivity into lipids by human blood V. Pattern of fatty acid radioactivity in lipid fractions of platelets 放射性通过人体血液进入脂质的研究。血小板脂质部分脂肪酸放射性的模式
Allen R. Hennes, Kozi Awai, Kent Hammarstrand
{"title":"Studies of incorporation of radioactivity into lipids by human blood V. Pattern of fatty acid radioactivity in lipid fractions of platelets","authors":"Allen R. Hennes,&nbsp;Kozi Awai,&nbsp;Kent Hammarstrand","doi":"10.1016/0926-6542(64)90132-5","DOIUrl":"10.1016/0926-6542(64)90132-5","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 610-612"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90132-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23799449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Glyceride distribution of fatty acids assimilated by adipose tissue 脂肪酸被脂肪组织吸收的甘油分布
R.L. Anderson , S.B. Tove
{"title":"Glyceride distribution of fatty acids assimilated by adipose tissue","authors":"R.L. Anderson ,&nbsp;S.B. Tove","doi":"10.1016/0926-6542(64)90121-0","DOIUrl":"10.1016/0926-6542(64)90121-0","url":null,"abstract":"<div><p>Palmitic acid, stearic acid, oleic acid and linoleic acid assimilated by epididymal fat pads of mice are primarily esterified at the α-positions of triglycerides. A similar glyceride distribution is observed for fatty acids synthesized from acetate or glucose. Increasing the supply of α-glycerylphosphate by glucose addition did not appreciably affect the fatty acid distribution of the saturated fatty acids. In the presence of glucose the distribution of linoleic acid was uniform and oleic was variable. With palmitate, oleate and stearate, tissues from fasted animals demonstrated an increased disproportionality in α-esterification. This trend was only partially reversed by the addition of glucose to the medium. These results indicate at least two modes of incorporation of fatty acids into the triglycerides by adipose tissue. One provides for complete synthesis <em>de novo</em> and the other carries a high degree of specificity toward incorporation at the α-positions.</p></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 507-516"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90121-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23799439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Skeletal muscle lipids 骨骼肌脂质
E.J. Masoro, Loring B. Rowell, Rosa Mae Mc Donald
{"title":"Skeletal muscle lipids","authors":"E.J. Masoro,&nbsp;Loring B. Rowell,&nbsp;Rosa Mae Mc Donald","doi":"10.1016/0926-6542(64)90120-9","DOIUrl":"10.1016/0926-6542(64)90120-9","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. In order to effectivey explore the physiologic role of lipids in skeletal muscle, a method of analysis is needed to permit the separation and subsequent detailed examinatin of the lipid components. Such a method is described for the quantitative determination of the major and minor classes of lipids present in monkey skeletal muscle. Since the various lipid classes are quantitatively isolated, radioactivity in the lipid components is also easily determined.</p></span></li><li><span>2.</span><span><p>2. About one-third of the lipid is neutral lipid and two-thirds phospholipid. The neutral lipid is primarily triglyceride and cholesterol. More than 50% of the phospholipid is lecithin and about 25% is phosphatidylethanolamine. Appreciable quantities of phosphatidylinositol and “polyglycerophosphatide” are also present. The plasmalogen/lipid-phosphorus molar ratio is considerably greater than that reported for muscles of other species.</p></span></li><li><span>3.</span><span><p>3. The method was applied to an analysis of monkey gastrocnemius and soleus muscles. The lipid composition of a bilateral pair of muscles is found to be sufficiently similar to permit physiological investigation in which one of the bilateral pair serves as a control as the other undergoes contraction. While the functionally different soleus and gastrocnemius muscles are found to have similar lipid compositions, certain definite differences in the nature of their lipids are uncovered.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 493-506"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90120-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87667586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 67
Fatty acid composition in developing rats 发育大鼠脂肪酸组成
M. Dobiášová, P. Hahn, O. Koldovský
{"title":"Fatty acid composition in developing rats","authors":"M. Dobiášová,&nbsp;P. Hahn,&nbsp;O. Koldovský","doi":"10.1016/0926-6542(64)90124-6","DOIUrl":"10.1016/0926-6542(64)90124-6","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. The fatty acid composition of triglycerides and phospholipids isolated from the lungs, adipose tissue, intestine and liver was determined in newborn rats, in rats aged 1, 10 and 30 days, and in adult animals.</p></span></li><li><span>2.</span><span><p>2. Only the myristic and lauric acid contents of the triglycerides were found to change with changes in their content in the diet (milk against the solid diet for adult animals). Marked changes occurred in the fatty acid composition of the triglycerides during development in the different organs but these could not always be related to changes in the composition of the diet.</p></span></li><li><span>3.</span><span><p>3. The composition of fatty acids in the phospholipids differed with age and between organs. The lungs had the most specialized phospholipids, containing the aldehydes of stearic and palmitic acids and differing from the other organs also in their content of the other acids. Changes in the fatty acid composition of the diet were not reflected in the fatty acid composition of the phospholipids, although pronounced developmental changes were observed.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 538-549"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90124-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84291314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Proteolipids
M.L. Das, D.E. Myers, F.L. Crane
{"title":"Proteolipids","authors":"M.L. Das,&nbsp;D.E. Myers,&nbsp;F.L. Crane","doi":"10.1016/0926-6542(64)90135-0","DOIUrl":"10.1016/0926-6542(64)90135-0","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 618-620"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90135-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82721287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The incorporation of 32P from triphosphate into polyphosphoinositides [γ-32P]adenosine and phosphatidic acid in erythrocyte membranes 来自三磷酸的32P在红细胞膜内与多磷酸肌醇[γ-32P]腺苷和磷脂酸结合
Lowell E. Hokin , Mabel R. Hokin
{"title":"The incorporation of 32P from triphosphate into polyphosphoinositides [γ-32P]adenosine and phosphatidic acid in erythrocyte membranes","authors":"Lowell E. Hokin ,&nbsp;Mabel R. Hokin","doi":"10.1016/0926-6542(64)90126-X","DOIUrl":"10.1016/0926-6542(64)90126-X","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Erythrocyte ghosts incubated with [γ-<sup>32</sup>P]ATP incorporate radioactivity into diphosphoinositide, triphosphoinositide, phosphatidic acid, and into at least one unidentified lipid.</p></span></li><li><span>2.</span><span><p>2. Over 90% of the radioactivity incorporated into the polyphosphoinositides is in the monoesterified phosphates.</p></span></li><li><span>3.</span><span><p>3. Exogenous phosphatidyl inositol increases the labeling in diphosphoinositide by about 30% and in the unidentified compound by about 200%. The labeling in triphosphoinositide is inhibited.</p></span></li><li><span>4.</span><span><p>4. Kinetic studies of the labeling of the polyphosphoinsitides fail to provide evidence that the exchange of phosphate in the monoesterified positions is an intermediate reaction in the magnesium-dependent, sodium and potassium-activated ATPase.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 563-575"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90126-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23799444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 77
Utilization of individual non-esterified fatty acids by the isolated perfused rat heart 离体灌注大鼠心脏对个别非酯化脂肪酸的利用
A.F. Willebrands
{"title":"Utilization of individual non-esterified fatty acids by the isolated perfused rat heart","authors":"A.F. Willebrands","doi":"10.1016/0926-6542(64)90131-3","DOIUrl":"10.1016/0926-6542(64)90131-3","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 607-610"},"PeriodicalIF":0.0,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90131-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23799448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信