Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects最新文献

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The site of action of atractyloside 白术苷的作用部位
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-10-23 DOI: 10.1016/0926-6569(64)90290-1
A. Kemp Jr., E.C. Slater
{"title":"The site of action of atractyloside","authors":"A. Kemp Jr., E.C. Slater","doi":"10.1016/0926-6569(64)90290-1","DOIUrl":"10.1016/0926-6569(64)90290-1","url":null,"abstract":"","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"92 1","pages":"Pages 178-180"},"PeriodicalIF":0.0,"publicationDate":"1964-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90290-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23795496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 53
The effect of systemic administration of haematin on the tryptophan pyrrolase activity of rat liver 全身给予血红素对大鼠肝脏色氨酸吡咯酶活性的影响
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-10-23 DOI: 10.1016/0926-6569(64)90267-6
M.V. Jago, J.F. Nelson, S. Rose
{"title":"The effect of systemic administration of haematin on the tryptophan pyrrolase activity of rat liver","authors":"M.V. Jago,&nbsp;J.F. Nelson,&nbsp;S. Rose","doi":"10.1016/0926-6569(64)90267-6","DOIUrl":"10.1016/0926-6569(64)90267-6","url":null,"abstract":"<div><p>The saturation with cofactor of the tryptophan pyrrolase of rat liver was markedly increased by intravenous administration of solutions of haematin. Complete saturation followed the administration of 0.5–1 μmole haematin per 100 g body weight or larger amounts. No significant increase in tryptophan pyrrolase activity accompanied or followed this apparent saturation of the enzyme with cofactor <em>in vivo</em>.</p></div>","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"92 1","pages":"Pages 44-51"},"PeriodicalIF":0.0,"publicationDate":"1964-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90267-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23793355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Oxidation of glycerol 1-phosphate by rat-liver mitochondria 大鼠肝脏线粒体氧化甘油1-磷酸
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-10-23 DOI: 10.1016/0926-6569(64)90281-0
G. Bianchi, G. Penso, G.F. Azzone
{"title":"Oxidation of glycerol 1-phosphate by rat-liver mitochondria","authors":"G. Bianchi,&nbsp;G. Penso,&nbsp;G.F. Azzone","doi":"10.1016/0926-6569(64)90281-0","DOIUrl":"10.1016/0926-6569(64)90281-0","url":null,"abstract":"","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"92 1","pages":"Pages 154-156"},"PeriodicalIF":0.0,"publicationDate":"1964-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90281-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23795487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The amino acid sequence around the reactive serine in calf-intestinal alkaline phosphatase 犊牛肠碱性磷酸酶活性丝氨酸周围的氨基酸序列
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-10-23 DOI: 10.1016/0926-6569(64)90271-8
Lorents Engström
{"title":"The amino acid sequence around the reactive serine in calf-intestinal alkaline phosphatase","authors":"Lorents Engström","doi":"10.1016/0926-6569(64)90271-8","DOIUrl":"10.1016/0926-6569(64)90271-8","url":null,"abstract":"<div><p>The dipeptides Asp-SER<sup>32</sup>P and Ser<sup>32</sup>P-Ala have been isolated from an acid hydrolysate of calf-intestinal alkaline phosphate (orthophosphoric monoester phosphohydrolase, EC 3.I.3.I), which had been <sup>32</sup>P-labelled on a serine residue at the active site, as described earlier. This shows that the amino acid sequence aroun the active serine is ASP-Ser<sup>32</sup>P-Ala. The peptides were identified by using an acid hydrolysate of crytalline ovalbumin the same unballed peptides as reference substances.</p></div>","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"92 1","pages":"Pages 79-84"},"PeriodicalIF":0.0,"publicationDate":"1964-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90271-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83654410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Isolement d'un complexe enzyme d'échange ADP-ATP - cytochrome c réduit 分离ADP-ATP交换酶复合物-还原细胞色素c
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-10-23 DOI: 10.1016/0926-6569(64)90292-5
J. Laturaze, P.V. Vignais
{"title":"Isolement d'un complexe enzyme d'échange ADP-ATP - cytochrome c réduit","authors":"J. Laturaze,&nbsp;P.V. Vignais","doi":"10.1016/0926-6569(64)90292-5","DOIUrl":"10.1016/0926-6569(64)90292-5","url":null,"abstract":"","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"92 1","pages":"Pages 184-187"},"PeriodicalIF":0.0,"publicationDate":"1964-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90292-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79498550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The catalytic properties of cathepsin C 组织蛋白酶C的催化性能
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-09-18 DOI: 10.1016/0926-6569(64)90077-X
R.J. Planta , Jeannette Gorter, M. Gruber
{"title":"The catalytic properties of cathepsin C","authors":"R.J. Planta ,&nbsp;Jeannette Gorter,&nbsp;M. Gruber","doi":"10.1016/0926-6569(64)90077-X","DOIUrl":"10.1016/0926-6569(64)90077-X","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. The catalytic properties of the intracellular peptidase cathepsin C (EC 3.4.4.9) were investigated. The enzyme is devoid of the proteolytic activity that had been ascribed to it.</p></span></li><li><span>2.</span><span><p>2. Cathepsin C has a very narrow specificity. Its activity is restricted to the removal of N-terminal dipeptide units that meet a number of rigorous requirements, from amides, esters or polypeptides.</p></span></li><li><span>3.</span><span><p>3. In transamidation reactions cathepsin C shows a narrow specificity not only for the peptide “donor”—as in its hydrolytic activities—but also for the “acceptor” to which the dipeptide units are transferred.</p></span></li><li><span>4.</span><span><p>4. These enzymic properties make a function of cathepsin C in intracellular protein catabolism seem improbable.</p></span></li></ul></div>","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"89 3","pages":"Pages 511-519"},"PeriodicalIF":0.0,"publicationDate":"1964-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90077-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40771851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Enzymic preparation of nicotinate adenine dinucleotide (deamido-NAD) 酶法制备烟酸腺嘌呤二核苷酸(deamido-NAD)
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-09-18 DOI: 10.1016/0926-6569(64)90084-7
Tasuku Honjo, Masuyuki Ikeda, Antony J. Andreoli, Yasutomi Nishizuka, Osamu Hayaishi
{"title":"Enzymic preparation of nicotinate adenine dinucleotide (deamido-NAD)","authors":"Tasuku Honjo,&nbsp;Masuyuki Ikeda,&nbsp;Antony J. Andreoli,&nbsp;Yasutomi Nishizuka,&nbsp;Osamu Hayaishi","doi":"10.1016/0926-6569(64)90084-7","DOIUrl":"10.1016/0926-6569(64)90084-7","url":null,"abstract":"","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"89 3","pages":"Pages 549-552"},"PeriodicalIF":0.0,"publicationDate":"1964-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90084-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40771858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
The amide content of ferredoxin 铁氧还蛋白的酰胺含量
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-09-18 DOI: 10.1016/0926-6569(64)90085-9
E. Knight Jr., D.C. Blomstrom
{"title":"The amide content of ferredoxin","authors":"E. Knight Jr.,&nbsp;D.C. Blomstrom","doi":"10.1016/0926-6569(64)90085-9","DOIUrl":"10.1016/0926-6569(64)90085-9","url":null,"abstract":"","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"89 3","pages":"Pages 553-554"},"PeriodicalIF":0.0,"publicationDate":"1964-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90085-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40771859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The antagonistic action of magnesium ions and ethylenediaminetetraacetate on myosin A ATPase (potassium activated) 镁离子和乙二胺四乙酸酯对肌球蛋白A atp酶(钾活化)的拮抗作用
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-09-18 DOI: 10.1016/0926-6569(64)90090-2
G.W. Offer
{"title":"The antagonistic action of magnesium ions and ethylenediaminetetraacetate on myosin A ATPase (potassium activated)","authors":"G.W. Offer","doi":"10.1016/0926-6569(64)90090-2","DOIUrl":"10.1016/0926-6569(64)90090-2","url":null,"abstract":"","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"89 3","pages":"Pages 566-569"},"PeriodicalIF":0.0,"publicationDate":"1964-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90090-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40771863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Developmental changes in arginine: X amidinotransferase activity in streptomycin-producing strains of streptomyces 链霉菌产链霉素菌株精氨酸:X氨基转移酶活性的发育变化
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-09-18 DOI: 10.1016/0926-6569(64)90073-2
James B. Walker , Violette Schlatter Hnilica
{"title":"Developmental changes in arginine: X amidinotransferase activity in streptomycin-producing strains of streptomyces","authors":"James B. Walker ,&nbsp;Violette Schlatter Hnilica","doi":"10.1016/0926-6569(64)90073-2","DOIUrl":"10.1016/0926-6569(64)90073-2","url":null,"abstract":"<div><p>Among a number of microorganisms tested, only streptomycin- and hydroxystreptomycin-producing strains of Streptomyces contained high levels of the enzyme <span>L</span>-arginine: X amidinotransferase, so named because the physiological formamidine acceptor is not known. Of the several reactions common to known amidinotransferases, arginine: NH<sub>2</sub>OH transamidination was chosen for exploratory assays because of its unique compatibility with both single- and double-displacement reaction mechanisms. In high-enzyme strains, <em>Streptomyces griseus</em> ATCC 12475, <em>Streptomyces bikiniensis</em> ATCC 11062, and <em>Streptomyces griseocarneus</em> ATCC 12628, amidinotransferase activity is low from 0–24 h of growth on complex media, but increase 30-fold within the next 24 h. Lysozyme extracts of the derepressed mycelia have the highest amidinotransferase activity yet observed in nature. Mycelia harvested at 24 h and shaken in 1% NaCl exhibit a similar activity increase; this phenotypic change is prevented by low levels of neomycin. Since earlier workers have shown that streptomycin formation follows a similar time-course, the evidence is strong that X is an early precursor of the streptidine moiety of streptomycin. Biosynthesis of netropsin probably does not involve a transamidination.</p><p>Arginine: X amidinotransferase activity is strongly inhibited <em>in vitro</em> by cystine, cystamine, formamidine disulfide, and the mixed disulfide of cysteine and thiourea, but not by oxidized glutathione. These inhibitions are reversed by 2-mercaptoethanol.</p></div>","PeriodicalId":100170,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects","volume":"89 3","pages":"Pages 473-482"},"PeriodicalIF":0.0,"publicationDate":"1964-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6569(64)90073-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40771848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
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