The Royal Society of Chemistry最新文献_第9页

Brassica rapa L. crude polysaccharide meditated synbiotic fermented whey beverage ameliorates hypobaric hypoxia induced intestinal damage. Brassica rapa L. 粗多糖介导的益生菌发酵乳清饮料可改善低压缺氧诱发的肠道损伤。

IF 5.1 1区农林科学

Food & Function Pub Date : 2024-11-18 DOI: 10.1039/d4fo04667f

Yuanlin Niu, Tingting Zhao, Zhenjiang Liu, Diantong Li, Dongxu Wen, Bin Li, Xiaodan Huang

{"title":"Brassica rapa L. crude polysaccharide meditated synbiotic fermented whey beverage ameliorates hypobaric hypoxia induced intestinal damage.","authors":"Yuanlin Niu, Tingting Zhao, Zhenjiang Liu, Diantong Li, Dongxu Wen, Bin Li, Xiaodan Huang","doi":"10.1039/d4fo04667f","DOIUrl":"https://doi.org/10.1039/d4fo04667f","url":null,"abstract":"Hypobaric hypoxia causes oxidative stress and inflammatory responses and disrupts the gut microbiome and metabolome. In this study, we developed a synbiotic fermented whey beverage, combining kefir and Brassica rapa L. crude polysaccharides, to explore its protective effects against high-altitude induced injury in mice. The beverage, formulated with 0.8% (w/v) polysaccharides and kefir inoculation, demonstrated robust fermentation parameters and antioxidative capacity. When applied to a hypobaric hypoxia mouse model, the synbiotic fermented whey significantly reduced oxidation and protected the intestinal barrier by lowering inflammation, protecting the intestinal structure, increasing goblet cell counts, and reducing apoptosis. It also modulated the gut microbiota, enriching beneficial taxa as Intestinimonas and Butyricicoccaceae, while reducing harmful ones like Marvinbryantia and Proteus, and enhancing short-chain fatty acid (SCFA) production. Notably, the beverage increased berberine and nicotinic acid levels, activating the adenosine monophosphate-activated protein kinase (AMPK) signalling pathway and influencing nicotinate and nicotinamide metabolites linked to the suppression of Marvinbryantia, thereby alleviating intestinal inflammation and barrier damage. These effects contributed to the alleviation of hypoxia-induced intestinal damage in mice. This study highlights the potential of synbiotics and whey fermentation in novel nutritional interventions in high altitude environments.","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioaccessibility and unravelling of polyphenols, sulforaphane, and indoles biotransformation after in vitro gastrointestinal digestion of a novel lactofermented broccoli beverage. 新型乳发酵西兰花饮料体外胃肠道消化后多酚类物质、莱菔硫烷和吲哚生物转化的生物可及性和解明。

IF 5.1 1区农林科学

Food & Function Pub Date : 2024-11-18 DOI: 10.1039/d4fo03528c

José Ángel Salas-Millán, Encarna Aguayo

{"title":"Bioaccessibility and unravelling of polyphenols, sulforaphane, and indoles biotransformation after in vitro gastrointestinal digestion of a novel lactofermented broccoli beverage.","authors":"José Ángel Salas-Millán, Encarna Aguayo","doi":"10.1039/d4fo03528c","DOIUrl":"https://doi.org/10.1039/d4fo03528c","url":null,"abstract":"This study assesses the transformation and stability of polyphenols, sulforaphane, and indoles in a fermented beverage made from broccoli leaves during in vitro gastrointestinal digestion (GID). This process was simulated using a dialysis membrane to assess intestinal absorption. The total phenolic compounds (TPC) and antioxidant TEAC assays showed an increase in phytochemical content due to the GID process. The higher TPC and antioxidant activity observed after digestion was likely due to the enzymatic transformation of polyphenols in mildly alkaline conditions. Individual phytochemical analysis revealed that hydroxycinnamic acids, particularly 3CQa, remained stable initially but then decreased significantly during intestinal digestion. Acylated flavonoids exhibited a decrease during intestinal digestion, while deacylated flavonoids initially decreased before stabilising. This indicated the occurrence of enzymatic hydrolysis of more structurally complex flavonoids to glycosylated flavonoids such as kaempferol-3,7-diglucoside, and kaempferol-3-sophoroside-7-glucoside. Consequently, deacylated flavonoids were highlighted for their high bioaccessibility rate after in vitro GID. Glucosinolate-hydrolysis products, including sulforaphane and indoles, exhibited a general decrease during digestion, with sulforaphane showing 51% bioaccessibility. The study highlights the dialysed in vitro GID process, which affects the release and transformation of bioactive compounds, potentially increasing their bioaccessibility and the subsequent health benefits of the lactofermented beverage made from broccoli leaves.","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging 2D materials hardware for in-sensor computing. 用于传感器内计算的新兴二维材料硬件。

IF 8 2区材料科学

Nanoscale Horizons Pub Date : 2024-11-18 DOI: 10.1039/d4nh00405a

Yufei Shi, Ngoc Thanh Duong, Kah-Wee Ang

引用次数: 0

Solvent-free confinement of ordered microparticle monolayers: effect of host substrate and pattern symmetry. 有序微粒单层的无溶剂封闭：主基质和图案对称性的影响。

IF 2.9 3区化学

Soft Matter Pub Date : 2024-11-18 DOI: 10.1039/d4sm01196a

Ignaas S M Jimidar, Mitch T J de Waard, Gijs Roozendaal, Kai Sotthewes

{"title":"Solvent-free confinement of ordered microparticle monolayers: effect of host substrate and pattern symmetry.","authors":"Ignaas S M Jimidar, Mitch T J de Waard, Gijs Roozendaal, Kai Sotthewes","doi":"10.1039/d4sm01196a","DOIUrl":"https://doi.org/10.1039/d4sm01196a","url":null,"abstract":"The self-organisation of individual suspended colloids into ordered structures that can be mediated by confinement has garnered interest recently. Despite the push for solvent reduction for sustainability reasons, the comprehension and development of solvent-free assembly methods remain largely unaddressed. In this study, we explore the effect of confinement without rigid geometrical constraints, i.e., wall-less confinement on the assembly of monodisperse PMMA powder microspheres (diameters of 3 μm and 10 μm) on fluorocarbon-patterned heterogeneous substrates using a solvent-free rubbing assembly approach. Our findings reveal that the PMMA microspheres self-align on the fluorocarbon patterns, adapting to various geometrical shapes of these patterns through symmetry matching. The assembly process is driven by triboelectric charging and elastic properties of the microspheres and substrates. Moreover, we observe that the host substrate and the particle and pattern size ratio significantly influence the ordering of the microparticles on the fluorocarbon patterns. Ultimately, we demonstrate the successful use of fluorocarbon patterns to assemble tunable crystal patterns on rigid substrates, which typically do not exhibit any ordering.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positional effects of electron-donating and withdrawing groups on the photophysical properties of single benzene fluorophores. 供电子基团和取电子基团对单苯类荧光团光物理性质的位置效应。

IF 4.3 2区化学

Chemical Communications Pub Date : 2024-11-18 DOI: 10.1039/d4cc04451g

Dopil Kim, Jun Yeong Kim, Haein Kim, Eunjin Jeong, Minhyuk Lee, Dongwook Kim, JunWoo Kim, Myung Hwan Park, Min Kim

引用次数: 0

The thickness-dependent response of aerosol-jet-printed ultrathin high-aspect-ratio electrochemical microactuators. 气溶胶喷射打印超薄高宽比电化学微执行器的厚度依赖性响应

IF 2.9 3区化学

Soft Matter Pub Date : 2024-11-18 DOI: 10.1039/d4sm00886c

Ji Zhang, Jeremy J Baumberg, Sohini Kar-Narayan

{"title":"The thickness-dependent response of aerosol-jet-printed ultrathin high-aspect-ratio electrochemical microactuators.","authors":"Ji Zhang, Jeremy J Baumberg, Sohini Kar-Narayan","doi":"10.1039/d4sm00886c","DOIUrl":"10.1039/d4sm00886c","url":null,"abstract":"Trilayer electrochemical actuators comprising an electrolyte layer sandwiched between two electrode layers have been shown to exhibit large deformations at low actuation voltages. Here we report the aerosol-jet printing (AJP) of high-aspect-ratio bending-type trilayer electrochemical microactuators comprised of Nafion as the electrolyte and poly(3,4-ethylenedioxythiophene)polystyrene sulfonate (PEDOT:PSS) as the electrode. We investigated how the thicknesses of the electrolyte and electrode layers affect the DC response of these actuators by fabricating high-aspect-ratio trilayer cantilevers with varied layer thicknesses (0.36 μm to 1.9 μm-thick electrodes, and 3.5 μm to 12 μm-thick electrolyte layers). We found that the transported charge and angular deflection are proportional to the applied voltage at steady state, and the charge-to-voltage ratio scales with the PEDOT:PSS thickness. The deflection-to-voltage ratio is found to be strongly affected by the Nafion electrolyte thickness, showing a decreasing trend, but is less affected by the PEDOT:PSS thickness in the range of dimensions fabricated. The timescales for deflection are found to be generally longer than the timescales for charge transfer and no clear trend is observed with respect to layer thicknesses. This work establishes an experimental protocol in geometry optimisation of printed electrochemical microactuators, verifies the applicability of a theoretical model, and lays the groundwork for designing and optimising more sophisticated printed electrochemical microactuation systems.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical sensors based on composites of porous Fe₃O₄/C and carbon black for sensitive and rapid detection of propofol. 基于多孔 Fe3O4/C 和炭黑复合材料的电化学传感器，用于灵敏快速地检测异丙酚。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-11-18 DOI: 10.1039/d4ay01280a

Shouhui Chen, Dan Zhou, Qinghao Xiong, Yinan Yang, Mingyang Zhang, Shoulin Chen

{"title":"Electrochemical sensors based on composites of porous Fe3O4/C and carbon black for sensitive and rapid detection of propofol.","authors":"Shouhui Chen, Dan Zhou, Qinghao Xiong, Yinan Yang, Mingyang Zhang, Shoulin Chen","doi":"10.1039/d4ay01280a","DOIUrl":"https://doi.org/10.1039/d4ay01280a","url":null,"abstract":"Nowadays, many people are turning to medications that can help them stay calm during surgeries and their daily lives. As an anesthetic that reduces the excitability of nerve cells, propofol can achieve sedation with the advantages of fast onset and short half-life. The development of propofol sensors has tremendous application potential because they can help healthcare professionals dynamically regulate the concentration of propofol in the blood, not only to achieve the painless surgeries that patients want, to maintain the sedation that surgeons desire, but also to prevent the respiratory failure that may occur with a patient's daily sleep aids. In this paper, we prepared Fe3O4/C/CB nanocomposites by doping carbon black on the surface of the pyrolyzed product of MIL-88B. The nanocomposites-modified glassy carbon electrodes were used to detect propofol in phosphate buffer solution. The porous nanocomposites with high electrical conductivity promoted the charge transfer on the electrode surface, improving the performance of the modified electrodes. After optimization, the linear range, the detection limit, and the sensitivity for propofol were 5.0-205 μM, 0.102 μM, and 2.850 μA cm-2 μM-1, respectively. The electrochemical sensing of propofol in a medical propofol emulsion injection and in normal human serum showed that the method was rapid and repeatable.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improved volatiles analysis workflows using automated selected ion flow tube mass spectrometry (SIFT-MS). 利用自动选择离子流管质谱（SIFT-MS）改进挥发物分析工作流程。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-11-18 DOI: 10.1039/d4ay01707b

Vaughan S Langford, Mark J Perkins

{"title":"Improved volatiles analysis workflows using automated selected ion flow tube mass spectrometry (SIFT-MS).","authors":"Vaughan S Langford, Mark J Perkins","doi":"10.1039/d4ay01707b","DOIUrl":"https://doi.org/10.1039/d4ay01707b","url":null,"abstract":"Selected ion flow tube mass spectrometry (SIFT-MS) is a recent addition to the routine analysis and research laboratory toolkit, primarily as a quantitative tool. SIFT-MS employs ultra-soft chemical ionisation to directly analyse volatile organic compounds (VOCs) in air and headspace in real-time with high specificity and sensitivity. Coupling SIFT-MS with conventional laboratory automation equipment (i.e., that used with chromatography systems) has proved straightforward and enables unattended operation, processing up to 230 samples per day per SIFT-MS instrument. Automated SIFT-MS systems have been applied to analysis of headspace (static, continuous, multiple headspace extraction, and standard additions), sample bags, and thermal desorption tubes. Applications using these approaches include consumer and drug product testing for volatile impurities (such as benzene, formaldehyde, and nitrosamines), environmental samples, clinical research, and materials testing. The stability of the SIFT-MS technique, coupled with its ability to analyse diverse VOCs in a single run, removes the need for system configuration changes and hence reduces calibration demand and streamlines workflows, reducing the time to report the first results in a sequence schedule and increasing sample throughput compared to chromatographic systems. This article reviews the development of the automated-SIFT-MS approach using a variety of application examples and recommends hardware and software improvements that could further enhance its adoption.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct dimethyl carbonate synthesis from CO2 and methanol over a flower-like CeO2 catalyst with 2-cyanopyridine as a dehydrating agent in continuous packed-bed reactor 在连续填料床反应器中，以 2-氰基吡啶为脱水剂，在花状 CeO2 催化剂上从二氧化碳和甲醇直接合成碳酸二甲酯

IF 3.9 3区化学

RSC Advances Pub Date : 2024-11-18 DOI: 10.1039/D4RA06187J

Issara Sereewatthanawut, Notsawan Swadchaipong, Vut Tongnan, Chalempol Khajonvittayakul, Panupan Maneesard, Rossarin Ampairojanawong, Ammarika Makdee, Matthew Hartley, Kang Li and Unalome Wetwatana Hartley

{"title":"Direct dimethyl carbonate synthesis from CO2 and methanol over a flower-like CeO2 catalyst with 2-cyanopyridine as a dehydrating agent in continuous packed-bed reactor","authors":"Issara Sereewatthanawut, Notsawan Swadchaipong, Vut Tongnan, Chalempol Khajonvittayakul, Panupan Maneesard, Rossarin Ampairojanawong, Ammarika Makdee, Matthew Hartley, Kang Li and Unalome Wetwatana Hartley","doi":"10.1039/D4RA06187J","DOIUrl":"https://doi.org/10.1039/D4RA06187J","url":null,"abstract":"A flower-like CeO2 catalyst was successfully synthesized using an acrylamide graft copolymerized on glucose under hydrothermal conditions and used for the direct synthesis of dimethyl carbonate (DMC) from CO2 and CH3OH in a packed-bed reactor with 2-cyanopyridine as a dehydrating agent. The synthesized flower-like CeO2 exhibited both basicity and acidity properties with values of 300 μmol g−1 and 80 μmol g−1, respectively, according to CO2-TPD and NH3-TPD results. The effect of reaction parameters such as reaction temperature, feed ratio, catalyst quantity, and operating pressure on the DMC production over the flower-like CeO2 catalyst was investigated. The optimum conditions were found to be a temperature of 120 °C, catalyst weight of 1.0 g, CH3OH : CO2 ratio of 1 : 1, and pressure of 30 bar, which provided the highest CH3OH conversion, DMC selectivity, and DMC yield of 86.6%, 99.3%, and 86.0%, respectively. Furthermore, no changes were observed in the structure, morphology, and particle size of the flower-like CeO2 catalyst after the DMC synthesis reaction, indicating that the synthesized catalyst was resistant to the reaction test under such optimum reaction conditions.","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 49","pages":" 36771-36781"},"PeriodicalIF":3.9,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/ra/d4ra06187j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fibrotaxis: gradient-free, spontaneous and controllable droplet motion on soft solids. Fibrotaxis：软固体上的无梯度、自发和可控液滴运动。

IF 2.9 3区化学

Soft Matter Pub Date : 2024-11-18 DOI: 10.1039/d4sm01022a

Sthavishtha R Bhopalam, Jesus Bueno, Hector Gomez

引用次数: 0