中华老年医学杂志最新文献

{"title":"Research progress of epidemiology and non-pharmaceutical intervention of Alzheimer's disease: an update","authors":"Chao Huang, Wei Liu, Yuan Lyu, Jianjun Liu","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.020","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.020","url":null,"abstract":"A community-based, comprehensive intervention approach can not only improve the condition of AD patients from cognitive, memory and mood, improve the quality of life, stimulate of nerve cell growth and self-care, but also reduce the pressure on the patient's family and caregivers, and on society.This paper mainly focuses on the current status of AD epidemiology and the non-pharmaceutical interventions at home and abroad, and provides a reference for improving the quality of life of the elderly. \u0000 \u0000 \u0000Key words: \u0000Alzheimer disease; Epidemiology; Intervention studies","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"100-105"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46482055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between polycyclic aromatic hydrocarbons and rheumatoid arthritis","authors":"Xiaoya Li, Huizhen Fan, Jiang Li, Danping Fan, Xiangchen Lu, Shuang Lyu, Ya Xia, Cheng Xiao","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.013","url":null,"abstract":"Objective \u0000To analyze the association between polycyclic aromatic hydrocarbons(PAHs)exposure and rheumatoid arthritis(RA)based on large sample data. \u0000 \u0000 \u0000Methods \u0000The RA patients(RA group)and non-RA patients(non-RA group)with complete data were selected from the National Health and Nutrition Survey Database in the United States(NHANES)(2005—2014). The logistic regression model was used to analyze the association between 8 monohydroxylated(OH-)PAH metabolites in the urine and RA. \u0000 \u0000 \u0000Results \u0000A total of 357 RA patients and 5, 256 non-RA participants were included.After adjusting the confounding factors by logistic analysis, the level of OH-PAHs mixture at the highest quartile(Q4)was associated with increased risk of RA compared with that at the lowest quartile(Q1)(OR=1.60, 95%CI: 1.16-2.23). For a single kind of OH-PAHs, the Q4 levels of 1-hydroxynaphthalene(OR=1.59, 95%CI: 1.14-2.23), 2-hydroxynaphthalene(OR=1.66, 95%CI: 1.19-2.32), 2-hydroxyfluorene(OR=1.61, 95%CI: 1.17-2.22), 3-hydroxyfluorene(OR=1.64, 95%CI: 1.18-2.27)and 1-hydroxyphenanthrene(OR=1.38, 95%CI: 1.00-1.94)were all associated with significantly increased risk of RA compared with the Q1 level(all P<0.05). However, the Q2 level of 1-hydroxypyrene(OR=0.60, 95%CI: 0.43-0.83)was related to a decreased incidence of RA(P<0.01). \u0000 \u0000 \u0000Conclusions \u0000OH-PAHs mixed exposure is a risk factor for RA.The association between the level of individual OH-PAH and the rate of RA is bidirectional and is depended on the type and concentration of OH-PAHs. \u0000 \u0000 \u0000Key words: \u0000Arthritis, rheumatoid; Polycyclic compounds; Hydrocarbons, aromatic","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44289496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment for left main coronary artery stenosis in patients of advanced age","authors":"Ming-yang Zhou, Xiubin Yang, K. Hua, B. Mao, Liang Zhang","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.009","url":null,"abstract":"Objective \u0000To analyze the clinical efficacy of coronary artery bypass grafting(CABG)in patients of advanced age with left main coronary artery disease(LMCAD). \u0000 \u0000 \u0000Methods \u0000From 2005 to 2014, 101 elderly patients(≥80 years)with LMCAD underwent off-pump CABG in our hospital.Among them, 82 were male and 19 were female, with an average age of(81.4±1.7)years.Seventy-six cases(75.2%)had significant left main stenosis(≥70%)and twenty-five cases had left main stenosis less than 70%.The average left ventricular end diastolic diameter was(48.2±8.3)cm; left ventricular ejection fraction was more than 50% in 89 cases and 30% to 50% in 12 cases.Fourteen cases had mitral insufficiency and one had ventricular aneurysm.In addition, 56 patients had New York Heart Association functional classification Ⅰ to Ⅱ, and 45 patients had classification Ⅲ to Ⅳ.Ninety-nine patients had Canadian Vascular Society(CCS)classification of angina pectoris Ⅰto Ⅲ, two had classification Ⅳ and thirteen had acute myocardial infarction.Six patients were implanted with intra-aortic balloon counterpulsation before CABG. \u0000 \u0000 \u0000Results \u0000The average operation time was(3.9±0.8)h, the average number of bridging vessels were(3.0±1.0)roots, ICU monitoring time was(50.2±46.0)h, and ventilator assisted breathing time was(42.9±68.5)h.Six patients(5.9%)had secondary thoracotomy hemostasis, five(4.9%)had secondary tracheal intubation, and four(4.0%)had continuous dialysis.Intra-aortic balloon counterpulsation was implanted in 3cases(2.9%)during operation and in 11 cases(10.9%)after operation.Two cases(2.0%)had perioperative myocardial infarction and 8 cases(7.9%)died after operation during hospitalization.The median follow-up time was 6(1-11)years, and 17(16.8%)had all-cause mortality. \u0000 \u0000 \u0000Conclusions \u0000Although the two independent high-risk factors, old age and left main stenosis often coexist, off-pump CABG and perioperative management are still safe and effective treatments. \u0000 \u0000 \u0000Key words: \u0000Coronary disease; Coronary artery bypass, off-pump","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44639197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of bone mineral density and bone metabolism in elderly hip fracture patients of different genders","authors":"Ping Zhang, Yuan Yuan, Xiaoyu Li, Xiaoyan Liu, Bin Fan, Xinping Li, Xinbao Wu","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.011","url":null,"abstract":"Objective \u0000To understand changes and characteristics of bone mineral density(BMD)and early-stage bone turnover biochemical markers in elderly hip fracture patients of different genders. \u0000 \u0000 \u0000Methods \u0000This was a retrospective cohort study.A total of 1 161 elderly patients with hip fractures hospitalized in Beijing Jishuitan Hospital from May 2015 to December 2017 were enrolled.Based on gender, patients were divided into the female group(n=831)and the male group(n=330). Clinical data, BMD, serum type I procollagen amino terminal propeptide(P1NP), and 25-hydroxyvitamin D3 [25-(OH)VD3], type I collagen cross-linked carboxy terminal peptide beta degradation products(β-CTX), osteocalcin(OC)and parathyroid hormone(PTH)were measured and compared between the two groups. \u0000 \u0000 \u0000Results \u0000Of the 1 161 elderly patients with hip fractures, 831 were female and 330 were male.The BMD of the lumbar vertebrae and the total hip in the female and male groups showed that 30.4%(353/1 161)and 6.8%(79/1 161)had T≥-1.0 SD respectively; 36.6%(425/1 161)and 44.7%(519/1 161)had -2.5 SD 0.05). The levels of tP1NP, β-CTX, OC and PTH in females were higher than those in males, and the level of 25-(OH)VD3 was lower than that in males(all P<0.05). As the T value decreased, β-CTX and OC increased and 25-(OH)VD3 decreased accordingly(all P<0.05). \u0000 \u0000 \u0000Conclusions \u0000With the increase of age, the BMD T value in elderly patients with hip fractures shows a downward trend, but its decline in women is faster and earlier.Overall, the BMD T value is not sensitive enough for osteoporosis diagnosis or hip fracture prediction in the elderly, especially in men.In the early stage of fractures, the bone turnover biochemical markers show varying degrees of change, and bone resorption and bone formation are both reduced.The significance of OC, β-CTX and VD levels in early bone metabolic abnormalities requires further study. \u0000 \u0000 \u0000Key words: \u0000Osteoporosis; Hip fractures; Bone density","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43388564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Older couple-based studies on collaborative management of chronic diseases: basic theory and findings","authors":"Min Wu","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.021","url":null,"abstract":"China's limited community medical resources cannot meet the needs of chronic disease prevention and treatment due to the rapidly growing ageing population.The improvement and long-term maintenance of patient's self-management is essential for chronic disease management.In view of chronic disease management having a characteristic of being carried out in the family for a long time in recent years, it has been proposed that the key role of spouse in the management of chronic disease should not be underestimated.This article reviews the epidemiological evidence, theoretical foundations and interventional findings of elderly couples' collaborative management with chronic diseases, aiming to provide the evidence for efficiently conducting chronic disease management for community-dwelling older adults. \u0000 \u0000 \u0000Key words: \u0000Spouses; Chronic disease; Disease management; Lifestyle","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"106-110"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44693967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of left atrial function in elderly patients with ischemic mitral regurgitation by real-time three-dimensional speckle tracking imaging","authors":"Jing-mei Jiang, Zhirong. Jiang, Xiaofan Wang, Q. Lyu, Xiaoxia Song","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.005","url":null,"abstract":"Objective \u0000To assess left atrial(LA)function by evaluating changes of LA wall movement and volume detected by real-time three-dimensional speckle tracking imaging(RT3D-STI)in elderly patients with ischemic mitral regurgitation(IMR). \u0000 \u0000 \u0000Methods \u0000Eighty-six elderly patients with coronary heart disease(CHD)were enrolled in this study.According to whether or not to have IMR, the patients were divided into the pure CHD group(n=32)and the CHD-induced ischemic mitral regurgitation(IMR)group(n=54, including 20 cases of mild IMR, 18 cases of moderate IMR and 16 cases of severe IMR). Thirty-two healthy elderly volunteers were considered as control group.RT3D-STI was used to evaluate the global atrial longitudinal strain(GLS), global circumferential strain(GCS), global radial strain(GRS)and LA maximal, minimal and pre-systolic volumes(LAVmax, LAVmin, and LAVp). LA ejection fraction(LAEF), LA passive ejection fraction(LApEF)and LA active ejection fraction(LAaEF)were calculated.The relationship of LA volume changes and myocardial strain with LA function was analyzed. \u0000 \u0000 \u0000Results \u0000The left ventricular ejection fraction(LVEF)and LAEF were reduced in CHD group and IMR group as compared with the control group, and were lower in IMR group than in CHD group(P<0.05). Compared with the control group, the LAVmin was increased, and the LAaEF was decreased in the IMR group(P<0.05). Compared with the control group, the GLS, GCS, GRS were declined in the CHD and IMR groups, and were lower in IMR group than in control group(P<0.05). Along with the increased severity of regurgitation, GLS, GCS, and GRS were decreased in varying degrees.The standard deviations of time to peak longitudinal strains(TLS-SD), of time to peak circumferential strains(TCS-SD), and of time to peak radial strain(TRS-SD)rose in the IMR group as compared with the control group(P<0.05). The myocardial motion indicators(GLS, GCS, GRS)had a quite strong correlation with LAEF in the CHD and IMR groups(CHD group: r=-0.745, -0.718 and 0.627, P=0.006, 0.007 and 0.009; IMR group: r=-0.785, -0.781, 0.643, P=0.006, 0.007 and 0.008). The receiver operating characteristic(ROC)curves analysis showed that the sensitivity and specificity of TLS-SD, TCS-SD and TRS-SD were 89.7% and 81.8%, 78.6% and 84.8%, 85.7% and 72.1%, respectively in the evaluation of LA function changes. \u0000 \u0000 \u0000Conclusions \u0000RT3D-STI can precisely and objectively assess the LA function changes by measuring the volume changes and tracing the myocardial motion in elderly IMR patients. \u0000 \u0000 \u0000Key words: \u0000Coronary disease; Mitral valve insufficiency; Echocardiography, three-dimensional; Atrail function, left","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49318336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pure erythroid leukemia transformed from myelodysplastic syndrome: a case report","authors":"Yi-Yan Feng","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.017","url":null,"abstract":"纯红系白血病是一种少见类型的急性白血病，老年发病多见，临床进展较快，中位生存期短，预后差。本研究中，我们分析1例骨髓增生异常综合征(MDS)转化纯红系白血病临床表现、治疗经过及临床诊断，并结合2016年世界卫生组织对造血和淋巴组织肿瘤分类关于红白血病的修订进行文献复习。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"89-91"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47042610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Berberine alleviates cerebral ischemia-reperfusion injury in type 2 diabetic rats by inhibiting endoplasmic reticulum stress-related inflammatory pathways","authors":"Chong Liu, Xuejiao Yang, N. Shen, Y. Di, Xuan Liu, Qiang Chen, Feng He, Huanming Li","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.014","url":null,"abstract":"Objective \u0000To examine the effects of Berberine(BBR)on inflammatory pathways related to endoplasmic reticulum stress(ERS)in the penumbra area following focal cerebral ischemia-reperfusion injury in type 2 diabetic rats. \u0000 \u0000 \u0000Methods \u0000A total of 72 healthy male Sprague-Dawley rats were fed a high-fat, high-sugar diet and injected with streptozotocin to establish a type 2 diabetes mellitus model.The diabetic rats were randomly divided by digital lottery method into a Sham operation group(Sham group), a diabetic rat + BBR treatment group(BBR group), a diabetic middle cerebral artery occlusion(MCAO)model group(MCAO group), and a diabetic rats MCAO + BBR treatment group(MCAO + BBR group). Six rats were included in each group.The two treatment groups received prespecified doses of BBR through gastric perfusion at 48 h, 24 h before surgery, and 6h after surgery.The MCAO model was prepared by a suture occlusion method.The neurological deficit scores were performed, and the expression of tumor necrosis factor-α(TNF-α)and interleukin-1β(IL-1β)was detected by enzyme-linked immunosorbent assay(ELISA). The mRNA expression of ERS marker protein GRP78 was detected by quantitative real time polymerase chain reaction(RT-qPCR), and the expression of ERS-related inflammatory pathway proteins[78 Glucoseregulated protein(GRP78)、Pancreatic endoplasmic reticulum Rinase(PERK)、nuclear factor-κB(NF-κB)]was detected by Western blot. \u0000 \u0000 \u0000Results \u0000the cerebral ischemic penumbra area, after 2 h of ischemia and 24 h of reperfusion, the neurological deficit score in the MCAO group was higher than that in the MACO+ BBR group [(2.83±0.41)vs.(1.67±0.52), P<0.05], and the expression levels of pro-inflammatory cytokines(TNF-α and IL-1β)and ERS-related inflammatory pathway proteins(GRP78, PERK and NF-κB p65)were also significantly increased(all P<0.05). However, BBR treatment was able to alleviate the neurological dysfunction caused by cerebral ischemia-reperfusion in type 2 diabetic rats(P<0.05). Similarly, BBR treatment also reduced the expression levels of pro-inflammatory factors(TNF-α and IL-1β)and ERS-related inflammatory pathway proteins(GRP78, PERK and NF-κB p65)in the cerebral ischemic penumbra area(all P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Through inhibiting ERS-related inflammatory pathways, BBR plays a neuroprotective role to alleviate cerebral ischemia-reperfusion injury in type 2 diabetic rats. \u0000 \u0000 \u0000Key words: \u0000Berberine; Inflammation; Diabetes, type 2; Brain ischemia","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"73-77"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48368400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arthroscopic treatment of subacromial impingement syndrome in older patients with full-thickness rotator cuff tears","authors":"Jun-Hui Pan","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.012","url":null,"abstract":"Objective \u0000To evaluate the clinical efficacy of arthroscopic acromioplasty and rotator cuff repair for older patients with full-thickness rotator cuff tears(RCTs). \u0000 \u0000 \u0000Methods \u0000This was a prospective cohort study.From January 2013 to December 2017, a total of 142 older patients with full-thickness RCTs were enrolled.Based on treatment methods, patients were divided into an arthroscopic rotator cuff repair group(operation group)and a conservative treatment group(control group). The operation group had 70 patients, including 26 males and 44 females, with an average age of 74.5 years(aged 66-83 years), and was followed up for≥12 months after surgery.The DEORIO and COFIELD criteria revealed 61 cases of medium tears and 9 cases of large tears in the operation group.The control group had 62 patients, including 27 males and 35 females, with an average age of 74.2 years(aged 65-82 years), and was followed up for≥12 months.There were 41 cases of medium tears and 21 cases of large tears, according to the DEORIO and COFIELD criteria.The visual analogue scale(VAS)scores, range of motion, Simple Shoulder Test(SST), Constant score were recorded pre-treatment and at 1-year post-treatment and compared between the two groups. \u0000 \u0000 \u0000Results \u0000132 older patients(70 in the operation group and 62 in the control group)were followed up for at least 1 year.There was no significant differences in VAS scores, range of motion, SST scores and the Constant score pre-treatment between the two groups(all P>0.05). However, the operation group was associated with significantly improved VAS scores, range of motion, SST scores and the Constant score at 1-year post-treatment, compared with the control groups(all P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Arthroscopic acromioplasty and rotator cuff repair can improve shoulder function in older patients with full-thickness RCTs.The long-term follow-up results will be studied further. \u0000 \u0000 \u0000Key words: \u0000Arthroswpes; Shoulder pain","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"62-66"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47066358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress in research on venous thromboembolism in elderly patients with lung cancer","authors":"Yi Wang, Ying-Qiu Tian, Li Sun","doi":"10.3760/CMA.J.ISSN.0254-9026.2020.01.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2020.01.018","url":null,"abstract":"Venous thromboembolism(VTE)is one of the common and serious complications of malignant tumors.In elderly lung cancer patients, problems such as decreased autonomic activity, bed rest, poor performance status(PS), combined underlying diseases and the use of chemoradiotherapy are often considered as risk factors for high incidence of VTE.This article is aimed to review the clinical features and pathogenesis of lung cancer in the elderly combined with VTE, to investigate the risk factors and explore feasible evaluation and prevention strategies. \u0000 \u0000 \u0000Key words: \u0000Lung neoplasms; Venous thromboembolism; Risk factors","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"39 1","pages":"92-95"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42288320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}