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中国临床药理学与治疗学最新文献

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Advances in study of phase II metabolic enzyme expression and activity under diseases status 疾病状态下II期代谢酶表达和活性的研究进展
中国临床药理学与治疗学 Pub Date : 2020-06-26 DOI: 10.12092/J.ISSN.1009-2501.2020.06.012
Zhang Yu, P. Ying, Wang Guang-ji, S. Jianguo
{"title":"Advances in study of phase II metabolic enzyme expression and activity under diseases status","authors":"Zhang Yu, P. Ying, Wang Guang-ji, S. Jianguo","doi":"10.12092/J.ISSN.1009-2501.2020.06.012","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.06.012","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"25 1","pages":"686"},"PeriodicalIF":0.0,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41870570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Resveratrol protects human retinal pigment epithelial cells from toxicity of high glucose by up-regulation of miR-26a 白藜芦醇通过上调miR-26a保护人视网膜色素上皮细胞免受高糖毒性
中国临床药理学与治疗学 Pub Date : 2020-03-26 DOI: 10.12092/J.ISSN.1009-2501.2020.03.007
Z. Haiyan, Wang Kailing
{"title":"Resveratrol protects human retinal pigment epithelial cells from toxicity of high glucose by up-regulation of miR-26a","authors":"Z. Haiyan, Wang Kailing","doi":"10.12092/J.ISSN.1009-2501.2020.03.007","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.03.007","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"18 2","pages":"285"},"PeriodicalIF":0.0,"publicationDate":"2020-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41300895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioequivalence of apixaban tablets in healthy Chinese subjects 阿哌沙班片在中国健康受试者体内的生物等效性
中国临床药理学与治疗学 Pub Date : 2020-03-26 DOI: 10.12092/J.ISSN.1009-2501.2020.03.010
Ning Xiaoyi, K. Yun, H. Jie, L. Yanan, Yang Xiaoyan, Yang Shuang, G. Can, Yang Guo-ping
{"title":"Bioequivalence of apixaban tablets in healthy Chinese subjects","authors":"Ning Xiaoyi, K. Yun, H. Jie, L. Yanan, Yang Xiaoyan, Yang Shuang, G. Can, Yang Guo-ping","doi":"10.12092/J.ISSN.1009-2501.2020.03.010","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.03.010","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"25 1","pages":"306"},"PeriodicalIF":0.0,"publicationDate":"2020-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42905205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethical issues in the prevention and control of Coronavirus Disease 2019 2019冠状病毒病防控中的伦理问题
中国临床药理学与治疗学 Pub Date : 2020-03-26 DOI: 10.12092/J.ISSN.1009-2501.2020.03.014
W. Xiaomin, Yang Guo-ping, Wang Bing, Zhong Yuqiong, Wu Ying, Liu Xing
{"title":"Ethical issues in the prevention and control of Coronavirus Disease 2019","authors":"W. Xiaomin, Yang Guo-ping, Wang Bing, Zhong Yuqiong, Wu Ying, Liu Xing","doi":"10.12092/J.ISSN.1009-2501.2020.03.014","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.03.014","url":null,"abstract":"Public health emergency is a huge challenge for all countries or regions It is impossible for any country or region to make adequate preparations in advance How to effectively prevent and control the spread of the epidemic is an unprecedented challenge for China and even the whole international community This paper holds that the current prevention and control measures and efforts of the Chinese government are effective and important for preventing and controlling the disease rapidly, but the ethical concerns cannot be ignored In fact, good ethical practices can help to achieve long-term prevention and control goals Based on the current situation of the epidemic, we propose six ethical points to further stimulate dialogue on how to implement disease prevention and control measures to better protect public safety, protect personal privacy, prevent stigma and discrimination, and guide society to follow the right ethical value orientation","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"25 1","pages":"329-333"},"PeriodicalIF":0.0,"publicationDate":"2020-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44966288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A surey of bioanalysis methods for antibody drugs 抗体药物生物分析方法的确定
中国临床药理学与治疗学 Pub Date : 2020-02-26 DOI: 10.12092/J.ISSN.1009-2501.2020.02.017
Zheng Fengjia, Jiao Zhijun, Xie Xinyao, Han Min, Dong Lihou
{"title":"A surey of bioanalysis methods for antibody drugs","authors":"Zheng Fengjia, Jiao Zhijun, Xie Xinyao, Han Min, Dong Lihou","doi":"10.12092/J.ISSN.1009-2501.2020.02.017","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.02.017","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"25 1","pages":"227"},"PeriodicalIF":0.0,"publicationDate":"2020-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41595932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances of the clinical pharmacology of hydroxychloroquine sulfate 硫酸羟氯喹临床药理学研究进展
中国临床药理学与治疗学 Pub Date : 2020-02-26 DOI: 10.12092/J.ISSN.1009-2501.2020.02.016
Cui Cheng, Yao Xueting, Tu Siqi, Xie Jieen, L. Haiyan, L. Dongyang
{"title":"Advances of the clinical pharmacology of hydroxychloroquine sulfate","authors":"Cui Cheng, Yao Xueting, Tu Siqi, Xie Jieen, L. Haiyan, L. Dongyang","doi":"10.12092/J.ISSN.1009-2501.2020.02.016","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.02.016","url":null,"abstract":"As the number of novel coronavirus disease (COVID-19) continues to increase, the medical situation is still critical, and potential therapeutic drugs, vaccines and stem cell replacement approaches are emerging. Chloroquine has shown better clinical antiviral efficacy than lopinavir/litonavir (clazidine) in clinical trials of small sample size. Since pharmacological action mechanism of hydroxychloroquine is similar with chloroquine and hydroxychloroquine is safer than chloroquine in the treatment of malaria and immunological diseases, the clinical pharmacology characteristics of hydroxychloroquine was reviewed, hoping to provide theoretical support for clinical effect verification of hydroxychloroquine from the perspective of clinical pharmacology and quantitative pharmacology.","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"25 1","pages":"221"},"PeriodicalIF":0.0,"publicationDate":"2020-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42618782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clinical characteristics of insulin autoimmune syndrome caused by methimazole in Chinese population 甲巯咪唑致中国人群胰岛素自身免疫综合征的临床特点
中国临床药理学与治疗学 Pub Date : 2020-02-26 DOI: 10.12092/J.ISSN.1009-2501.2020.02.014
Wang Chun-jiang, Sun Wei, Sun Linli
{"title":"Clinical characteristics of insulin autoimmune syndrome caused by methimazole in Chinese population","authors":"Wang Chun-jiang, Sun Wei, Sun Linli","doi":"10.12092/J.ISSN.1009-2501.2020.02.014","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.02.014","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"25 1","pages":"209"},"PeriodicalIF":0.0,"publicationDate":"2020-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47142489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Experience in quality control of clinical trials of DMARDs 具有dmard临床试验质量控制经验
中国临床药理学与治疗学 Pub Date : 2020-01-26 DOI: 10.12092/J.ISSN.1009-2501.2020.01.017
W. Xiaoxia, Wang Hong, Liu Yan, Bai Jie
{"title":"Experience in quality control of clinical trials of DMARDs","authors":"W. Xiaoxia, Wang Hong, Liu Yan, Bai Jie","doi":"10.12092/J.ISSN.1009-2501.2020.01.017","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2020.01.017","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"25 1","pages":"117"},"PeriodicalIF":0.0,"publicationDate":"2020-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43916103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on bioequivalence of gefitinib tablets in healthy Chinese subjects 吉非替尼片在中国健康人群中的生物等效性研究
中国临床药理学与治疗学 Pub Date : 2019-11-26 DOI: 10.12092/J.ISSN.1009-2501.2019.11.010
Wang Mengyao, H. Jie, L. Yanan, Yang Shuang, Wu Shuting, Y. Xiaoyan, Ye Ling, G. Can, Hu Zhi-jun
{"title":"Study on bioequivalence of gefitinib tablets in healthy Chinese subjects","authors":"Wang Mengyao, H. Jie, L. Yanan, Yang Shuang, Wu Shuting, Y. Xiaoyan, Ye Ling, G. Can, Hu Zhi-jun","doi":"10.12092/J.ISSN.1009-2501.2019.11.010","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2019.11.010","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"24 1","pages":"1275"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47325277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Hepatic macrophages in liver injury and repair 肝巨噬细胞在肝损伤及修复中的作用
中国临床药理学与治疗学 Pub Date : 2018-10-26 DOI: 10.12092/J.ISSN.1009-2501.2018.10.016
Wang Lu, L. Liping, Xing Xin, XU Dengqiu, X. Li, Jiang Zhen-zhou, Zhang Lu-yong, Sun Lixin
{"title":"Hepatic macrophages in liver injury and repair","authors":"Wang Lu, L. Liping, Xing Xin, XU Dengqiu, X. Li, Jiang Zhen-zhou, Zhang Lu-yong, Sun Lixin","doi":"10.12092/J.ISSN.1009-2501.2018.10.016","DOIUrl":"https://doi.org/10.12092/J.ISSN.1009-2501.2018.10.016","url":null,"abstract":"","PeriodicalId":9961,"journal":{"name":"中国临床药理学与治疗学","volume":"23 1","pages":"1188"},"PeriodicalIF":0.0,"publicationDate":"2018-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42759117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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