CHILDREN INFECTIONS最新文献_第8页

A clinical case of the new coronavirus infection with cardiac involvement in a child 儿童新型冠状病毒感染累及心脏临床1例

CHILDREN INFECTIONS Pub Date : 2022-10-02 DOI: 10.22627/2072-8107-2022-21-3-52-55

E. A. Gashina, E. Lobova, E. P. Shefer

引用次数: 0

Parvovirus В19 infection: lecture 细小病毒В19感染:讲座

CHILDREN INFECTIONS Pub Date : 2022-10-02 DOI: 10.22627/2072-8107-2022-21-3-39-46

T. Chernova, V. N. Timchenko, E. B. Pavlova, E. V. Baracina, M. Subbotina

引用次数: 0

Features of the epidemiological history of patients with Lyme borreliosis 莱姆病borreliosis患者流行病学史的特点

CHILDREN INFECTIONS Pub Date : 2022-10-02 DOI: 10.22627/2072-8107-2022-21-3-22-27

R. F. Sayfullin, N. Zvereva, M. A. Sayfullin, S. Smetanina, E. V. Kardonova, O. Shamsheva

{"title":"Features of the epidemiological history of patients with Lyme borreliosis","authors":"R. F. Sayfullin, N. Zvereva, M. A. Sayfullin, S. Smetanina, E. V. Kardonova, O. Shamsheva","doi":"10.22627/2072-8107-2022-21-3-22-27","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-3-22-27","url":null,"abstract":"In the treatment of Lyme borreliosis (LB), early diagnosis is a key component. The epidemiological history of the patient plays one of the leading roles in suspected borreliosis and at the same time is an important criterion for clinical diagnosis.Purpose. Analysis of epidemiological history data in outpatient cases of LB in Moscow.Material and methods. We conducted a retrospective, non-randomized, single-center cohort study, based on the analysis of data from 660 outpatient records of patients, referred by local physician with tick bite or suspicion of LB, and consulted by an infectious disease specialist on the basis of the Infectious clinical hospital No.1 in Moscow. For further analysis, patients were divided by age and the presence or absence of LB. Confirmation of LB was based on clinical and/or laboratory criteria using methods of enzyme immunoassay and immune blot.Results. We have updated the epidemiological features of the LB for Moscow, such as: the relative number of cases in the administrative districts of Moscow, places and seasonality of tick bites. Among children, compared with adults, cases of a tick bite without the development of LB was predominant, which must be taken into account in order to avoid overdiagnosis of LB. In patients with LB, an indication of the fact of tick bite in the anamnesis was much less common than going to its habitats.Conclusion. Our data clarify the epidemiological features of LB for residents of Moscow. In the absence of a history of indications of tick bite, an informative sign for clinical diagnosis is a visit to its habitats, including not only trips to wooded areas, but also to suburban areas and parks.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73023422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New coronavirus infection in a child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia 急性淋巴细胞白血病背景下与造血干细胞移植相关的严重继发性免疫缺陷儿童的新型冠状病毒感染

CHILDREN INFECTIONS Pub Date : 2022-10-02 DOI: 10.22627/2072-8107-2022-21-3-56-60

S. M. Bezrodnova, N. A. Yatsenkо, G. M. Sirazhov, Yu. N. Kashina

引用次数: 0

Marketing assessment of the potential of the Russian pharmaceutical market in the framework of etiotropic therapy of children with campylobacteriosis 在致病因治疗儿童弯曲杆菌病的框架下，对俄罗斯药品市场潜力的营销评估

CHILDREN INFECTIONS Pub Date : 2022-07-20 DOI: 10.22627/2072-8107-2022-21-2-38-45

D. D. Demchenko, K. Ermolenko, Y. Lobzin, I. Narkevich, O. D. Nemyatykh, V. N. Timchenko, Yu. V. Matlashevskaya

{"title":"Marketing assessment of the potential of the Russian pharmaceutical market in the framework of etiotropic therapy of children with campylobacteriosis","authors":"D. D. Demchenko, K. Ermolenko, Y. Lobzin, I. Narkevich, O. D. Nemyatykh, V. N. Timchenko, Yu. V. Matlashevskaya","doi":"10.22627/2072-8107-2022-21-2-38-45","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-2-38-45","url":null,"abstract":"The paper analyzes approaches to etiotropic therapy and structural assessment of the range of drugs for the treatment of campylobacteriosis in children. The methods of content analysis, grouping, data aggregation, comparative and marketing analysis were used. The information base of the study was the State Register of Medicines, federal clinical guidelines for the provision of medical care to children with campylobacteriosis, European and American clinical guidelines, as well as instructions for the medical use of drugs.Comparative analysis showed that Russian clinical guidelines contain 15 international non-proprietary names used for the etiotropic therapy of campylobacteriosis. The analysis carried out by drug producing countries shows that the leading positions in the supply structure are occupied by Russian producers (68.26%). Structuring by dosage forms makes it possible to single out tablet positions (47.46%). At the same time, 36.47% of the range of drugs are approved for use from the age of 12, which limits the implementation of modern approaches to the rational etiotropic therapy of campylobacteriosis in pediatrics. Structural analysis of the range of pharmaceutical substances identifies a significant contribution to the structure of imports of Chinese producers (46.30%), which, in turn, justifies the prospects for import substitution. Solving the problem of improving the quality of medical care for children with campylobacteriosis determines the prospects for further research based on the principles of evidence-based medicine using the tools of mathematical-statistical and pharmacoeconomic analyses.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82393064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infectious mononucleosis in children: clinical and laboratory criteria for assessing severity 儿童传染性单核细胞增多症:评估严重程度的临床和实验室标准

CHILDREN INFECTIONS Pub Date : 2022-07-20 DOI: 10.22627/2072-8107-2022-21-2-28-33

L. A. Ikkes, G. Martynova

{"title":"Infectious mononucleosis in children: clinical and laboratory criteria for assessing severity","authors":"L. A. Ikkes, G. Martynova","doi":"10.22627/2072-8107-2022-21-2-28-33","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-2-28-33","url":null,"abstract":"Рurpose: to identify clinical and laboratory criteria that mark the severity of infectious mononucleosis in children, with the identification of risk factors for the development of severe forms and unfavorable course.Patients and methods. A comparative prospective clinical study involved 200 children aged 3 to 11 years with moderate (125 people) and severe (75 people) form of infectious mononucleosis. When comparing clinical and laboratory data in the compared groups, the Mann-Whitney test was used. For multiple comparisons, the Kruskal-Wally test was used. Significance of differences was determined at a significance level of 0.05 (p < 0.05).Results. A comparative analysis of the clinical and laboratory manifestations of infectious mononucleosis revealed statistically significant differences in the studied parameters depending on the severity of the disease. Severe forms of infectious mononucleosis were distinguished by the most pronounced clinical symptoms, as well as changes in hematological parameters and biochemical changes. The combined etiology of infectious mononucleosis also contributed to a more severe course of the disease.Сonclusion. Timely diagnosis and assessment of the severity of the manifest form of infectious mononucleosis determine the adequacy of the appointment of rational antiviral and pathogenetic therapy, preventing the development of adverse effects and complications.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86703321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human Сysticercosis caused by Taenia solium, Taenia crassiceps, Taenia hydatigena, Taenia martis

CHILDREN INFECTIONS Pub Date : 2022-07-20 DOI: 10.22627/2072-8107-2022-21-2-46-50

S. B. Chuelov, A. L. Rossina

引用次数: 0

A case of reactivation of chronic Epstein-Barr viral infection, complicated by hepatitis, in a teenager with COVID-19 一名患有COVID-19的青少年慢性爱泼斯坦-巴尔病毒感染并发肝炎的再激活病例

CHILDREN INFECTIONS Pub Date : 2022-07-20 DOI: 10.22627/2072-8107-2022-21-2-57-59

A. V. Bitsueva, S. G. Gorbunov, I. A. Nikulina

引用次数: 0

Clinical and morphological characteristics of placentas of full-term infants with congenital infectious diseases 先天性传染病足月儿胎盘的临床和形态学特征

CHILDREN INFECTIONS Pub Date : 2022-07-20 DOI: 10.22627/2072-8107-2022-21-2-23-27

A. V. Agafonova, V. V. Vasiliev, N. Rogozina

{"title":"Clinical and morphological characteristics of placentas of full-term infants with congenital infectious diseases","authors":"A. V. Agafonova, V. V. Vasiliev, N. Rogozina","doi":"10.22627/2072-8107-2022-21-2-23-27","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-2-23-27","url":null,"abstract":"Materials and methods. The features of the course of pregnancy and childbirth, the condition of children at birth, histomorphological conclusions of placentas and the expression of the CD15 marker in the placentas of 40 children with congenital infectious diseases, 10 children with asphyxia at birth and 10 healthy full-term children were analyzed.Results. The analysis showed the absence of reliable clinical and morphological criteria for the risk of developing a congenital infectious disease. Thus, the majority of mothers of children of all comparison groups had various somatic pathology: 33 (82.5%) in group 1, 8 (80%) in group 2, 6 (60%) in group 3 (p ≥ 0.05) Children of all comparison groups were statistically comparable in gestational age, anthropometric data and assessment on the Apgar scale. During histological examination, inflammatory changes in the afterbirth in children of the compared groups were recorded with almost the same frequency: in 17 (42.5%) children with intrauterine infection, 4 (40%) with asphyxia at birth and 2 (20%) healthy children (p ≥ 0.05). At the same time, immunohistochemically, placentas of children with congenital infectious diseases were characterized by a significantly higher level of CD15 expression compared to placentas of healthy children: CD15 expression coefficient in placentas of children with congenital infectious diseases was 6.9 ± 0.9, in the group of healthy children — 0.7 ± 0.5, (p < 0.05).Conclusion. The use of the immunohistochemical marker CD15 makes it possible to predict congenital infectious disease in newborns in the absence of obvious morphological signs of an infectious lesion of the afterbirth, and can be used to form risk groups for the implementation of infectious pathology.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75565712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The risks of perinatal HIV/HCV co-infection and the evolution of treatment tactics of the disease in children (clinical case) 儿童围产期HIV/HCV合并感染的风险及治疗策略的演变(临床病例)

CHILDREN INFECTIONS Pub Date : 2022-07-20 DOI: 10.22627/2072-8107-2022-21-2-60-66

A. A. Khamatova, T. A. Chebotareva, J. F. Vlatskaya

{"title":"The risks of perinatal HIV/HCV co-infection and the evolution of treatment tactics of the disease in children (clinical case)","authors":"A. A. Khamatova, T. A. Chebotareva, J. F. Vlatskaya","doi":"10.22627/2072-8107-2022-21-2-60-66","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-2-60-66","url":null,"abstract":"HIV infection and HCV infection are still serious and widespread infections that lead to high morbidity and mortality of the population worldwide.The aim is to assess the risks of perinatal transmission of HIV/HCV co-infection and the choice of modern treatment tactics in children.Аnalyzed data in foreign and domestic literature. A clinical case of perinatal transmission of HIV/HCV co-infection is described.Results. Тhe features of perinatal transmission of infection depending on its variants (mono-HIV infection, hepatitis C and co-infection with HIV/HCV) and risk factors are shown. A clinical example demonstrates the implementation of perinatal transmission of HIV/HCV co-infection in the presence of major risk factors. The improvement of therapeutic tactics in a child with co-infection is shown.Conclusion: in the described clinical case, numerous risk factors for perinatal transmission of HIV/HCV co-infection are demonstrated, the presence of which led to the realization of co-infection in a child. The effectiveness of modern tactics for the treatment of HIV infection and chronic viral hepatitis C has been demonstrated.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85237435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0