Chattagram Maa-O-Shishu Hospital Medical College Journal最新文献

{"title":"Cytological Findings in Testicular FNAC in Azoospermia Patient: A Study of 395 Cases","authors":"Md. Saiful Islam, Papri Dutta, N. Dey, M. Kabir","doi":"10.3329/cmoshmcj.v22i1.67836","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67836","url":null,"abstract":"Background: In the age of assisted reproduction, search for the cause of male infertility is increasing in numbers. As finding of obstructive azoospermia give the male a hope there are increased requisition to the cytopathologist to evaluate the spermatogenesis status of a male. The aim of the study was to see the cytomorphological pattern in azoospermia patients and to determine the procedure's safety. \u0000Materials and methods:    From January 2015 to June 2022, in Chattogram, Bangladesh, 395 patients with azoospermia were taken in this descriptive study. After all aseptic precautions and local anesthetization aspiration was done from both testes. Cytomorphological analysis was done in the following classes i) Positive for spermatogenesis ii) Hypo-spermatogenesis iii) Early maturation arrest iv) Late maturation arrest v) Sertoli cell only vi) Atrophic. \u0000Results: Cytological diagnosis yielded 161 (40.76%) positive for spermatogenesis, indicating obstructive azoospermia, seconded by 'Sertoli cell only' in 115 (29.11%) patients. Both conditions were highest in the age group of 31-40, 93(57.76%) and 72 (62.6%). Hematoma was seen in 04(1.01%) cases and extended period of pain was experienced by 05 (1.26%) patients. \u0000Conclusion: FNA of the testis is a much simpler and easily accessible procedure to assess the spermatogenesis status of an azoospermia patient. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 53-56","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85665582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Predictors of Sodium Disturbance in Children Presenting with Acute Watery Diarrhea in a Tertiary Hospital of Bangladesh","authors":"F. Ara, Zabeen Choudhury, S. Hasan, Mosammat Zebunnesa, Rasheda Samad","doi":"10.3329/cmoshmcj.v22i1.67840","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67840","url":null,"abstract":"Background: Sodium disturbances, either hyponatremia or hypernatremia, are the most common electrolyte imbalance encountered in managing children with acute watery diarrhoea. Early diagnosis and prompt management of these conditions by identifying clinical predicting factors in diarrheal children under 5 years of age are critically essential to prevent deaths in such children, especially in resource-limited settings. Our study aimed to evaluate clinical predicting factors associated with sodium disturbance in children hospitalized with acute watery diarrhea. \u0000Materials and Methods: In this cross-sectional study, 121 children of 2 months to 5 years of age admitted in the Department of Pediatrics, Chittagong Medical College Hospital, Chattogram for acute watery diarrhea were included. Clinical features and sodium levels on admission were recorded. Children were grouped in hyponatremia (serum sodium <135mmol/l), hypernatremia (serum sodium >145mmol/l) and normonatremia (serum sodium 135–145mmol/l) and compared. \u0000Results: Of the 121 children, 18 (14.9%) were hyponatremic, 71 (58.7%) isonatraemic, and 32 (26.4%) hypernatraemic. Logistic regression analysis revealed that children who did not receive ORS before admission, had severe dehydration and lethargy on admission would be more likely to have hyponatremic dehydration. Children who were younger, received concentrated ORS, thirsty and had convulsions on admission would be more likely to have hypernatremic dehydration than children with isonatremia. \u0000Conclusion: The type of ORS used and age appears to be good predictors of sodium disturbance in children admitted with AWD. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 71-75","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"300 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75112248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced Abdominal Pregnancy of 32 Weeks with Alive Baby: A Rare Event","authors":"A. Malik","doi":"10.3329/cmoshmcj.v22i1.67841","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67841","url":null,"abstract":"Background: Abdominal pregnancy is a rare form of ectopic or extrauterine pregnancy with an incidence of 1:10000 and 1:30000. Advanced abdominal pregnancy is extremely rare with high maternal and perinatal mortality. \u0000Case Presentation: We report a case of abdominal pregnancy at 32 weeks gestation with persistent abdominal pain and severe anemia, who was referred from another hospital to our center with an Ultrasonogram, missed the diagnosis of abdominal pregnancy, which was confirmed in our center as abdominal pregnancy at 32 weeks with live fetus. With laparotomy a 1.2 kg female baby was born without much difficulty and post operative recovery was uneventful. But the baby died at 27Th post operative day. \u0000Conclusion: High index of clinical suspicion is necessary for early diagnosis of abdominal pregnancy and timely laparotomy with multidisciplinary surgical team can save the life of a mother. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 76-78","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75979894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to Anti-Seizure Medications in Children with Epilepsy Attending a Tertiary Care Center in Bangladesh","authors":"Dhananjoy Das, Wahida Akther, Tanuka Barua, Rehena Ahmed, Nazrul Quader Shikder, M. Chowdhury","doi":"10.3329/cmoshmcj.v22i1.67833","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67833","url":null,"abstract":"Background: Epilepsy is one of the most common neurological morbidities in children worldwide. Anti-Seizure Medication (ASM) is the mainstay of epilepsy treatment. Adherence to Anti-Seizure Medication (ASM) is the key to achieving seizure remission. So this study aimed to assess the adherence to anti-seizure medication among children with epilepsy and to identify the factors that influence adherence. \u0000Materials and methods: It was a cross-sectional study involving Infants and children aged six months to twelve years old with seizure disorder irrespective of etiology, taking anti-seizure medications for more than six months and receiving mono or polytherapy were enrolled as the study subject. Self-reporting measures were used to assess adherence. Patients' caregivers were interviewed for the assessment of adherence. Descriptive statistical analysis was used to analyze the data, and univariate analysis with a chi-square test was used to observe the association between the variables and adherence. \u0000Results: The mean±SD age of the participants was 34.75 ± 38.39 months. A significant association was found between the age of the respondent and compliance with anti-seizure medication (30.5± 27.25 vs. 39.99±36.67 months p=0.012). Males were more than females 28(70%) Vs. 12(30%). Most of the study subjects were belonging to lower-middle-class families 13(33.3%). The generalized onset of seizure was the frequent type of seizure 28(70%). The majority of the participants 24 (60%) did have a seizure with structural etiology. Most of the study subjects received monotherapy 34(85%). Sodium valproate 19(47.5%) was the most frequently used drug. Seizure remission was found in 28(70%) of the study population. No significant association was found between the treatment outcome and adherence to antiseizure medication (ASM). Adherence to ASM was found in 55% of this study. Unable to afford cost was found to be the main cause of non-adherence 14(35%). There is a significant association found between the duration of taking ASM and compliance with ASM (7.05 ± 5.3 vs. 17.56± 15.43 months p=0.005). \u0000Conclusion: Adherence to Anti-Seizure Medication (ASM) is low in our study. Unable to afford cost was the main factor accountable for non-adherence appropriate interventions are needed to improve ASM compliance and consequently treatment outcome. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 38-43","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88260511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Assessment of Cyclophosphamide and Mycophenolate Mofetil after Induction Treatment of Lupus Nephritis: A Single Center Quasi-Experimental Study","authors":"Rosanna Bintey Kamal","doi":"10.3329/cmoshmcj.v22i1.67831","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67831","url":null,"abstract":"Background: The comparative safety of immunosuppressive drugs such as cyclophosphamide and mycophenolate mofetil for patients with lupus nephritis remains controversial. The study aimed to investigate the specific side effects of cyclophosphamide and mycophenolate mofetil in lupus nephritis patient after induction treatment. \u0000Materials and methods: It was a quasi-experimental study performed in the Department of Nephrology of Chittagong Medical College Hospital. A total of 100 patients of lupus nephritis who fulfilled the designated criteria were enrolled in this study by non-probability voluntary sampling method. The treatment was given on patient’s choice. After screening and treatment initiation, patients were assessed at 12 and 24 weeks. All the data were compiled in a structured case record form. \u0000Results: In the present study 48 patients (53.3%) in mycophenolate mofetil group and 42 patients (46.7%) in intravenous cyclophosphamide group completed 24 weeks of induction treatment of lupus nephritis. Infections were common in both treatment groups but significantly higher with intravenous cyclophosphamide group ((33.3% vs. 8.3%). Upper gastrointestinal syndrome occurred with 20(41%) patients in mycophenolate mofetil group and 7(16.7%) patients in intravenous cyclophosphamide group (RR=5.8333). Regarding other adverse effect, 10 patients of intravenous cyclophosphamide and two patients of mycophenolate mofetil group had amenorrhea (23.8% vs.4.2%). Alopecia (11.9%) was seen only by intravenous cyclophosphamide group ((RR=0.0798). \u0000Conclusion: Induction therapy with Mycophenolate mofetil was superior to intravenous cyclophosphamide in lupus nephritis in this study. Mycophenolate mofetil appeared to be better tolerated than cyclophosphamide. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 28-32","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88725393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Intralesional Doxycycline in the Treatment of Cystic Hygroma","authors":"Ashfaq Nabi, A. Hanif, K. Hasina, J. Khan, N. Khan, Nazmul Hasan","doi":"10.3329/cmoshmcj.v21i2.63127","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63127","url":null,"abstract":"Background: Cystic lymphangioma is a congenital lymphatic malformation.The present study was conducted to find out the effects of intralesional Doxycycline in the treatment of cystic hygroma. \u0000Materials and methods: This prospective study was conducted among 30 children with cystic hygroma in the Division of Pediatric Surgery, Dhaka Medical college Hospital, Dhaka, from July 2019 to June 2021. All patients were followed up for six months. In every follow up size of the lesion was determined and adverse effects were also noted. \u0000Results: More than half of the cystic hygroma (53.3%) were in neck while 5 (16.6%) in axilla. Before treatment, the median size of cystic hygroma was 12.00 cm2 which significantly decreased to 0.75cm2after treatment (p<0.001). After treatment, 83.3% participants showed excellent response and 16.6% participants showed good response. Out of 30 patients, 33.3% had adverse effects which included pain (n=5), redness of skin (n=5), fever (n=5) and skin pigmentation (n=2). \u0000Conclusion: Doxycycline monotherapy resulted in a high rate of excellent clinical outcomes after a few treatments without increased need for subsequent operative resection. It was very cost effective also. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 40-43","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83495263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"List of Reviewers and Editors Vol. 21(2)","authors":"M. J. Uddin","doi":"10.3329/cmoshmcj.v21i2.63155","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63155","url":null,"abstract":"Abstract not available \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 68","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89061432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Cement Dust on Liver Function Parameters of Some Cement Factory Workers","authors":"Shahin Akhter, Md Sakhawat Mahmud Khan, M. Akhter, Arunima Datta, M. Begum","doi":"10.3329/cmoshmcj.v21i2.63090","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63090","url":null,"abstract":"Background: Cement dust is one of the major air pollutants and its exposure causes various problems. It has deleterious effect on vital organs and may affect liver function. This study was done to assess the effects of cement dust on liver function parameters of cement factory workers. \u0000Materials and methods: This case control study was conducted in the Department of Physiology, Chittagong Medical College, Chattogram in collaboration with Heidelberg Cement Bangladesh Ltd. Chattogram during January 2018 to December 2018. For these, 30 cement exposed workers of Heidelberg Cement Bangladesh Ltd. aged between 20-45 years were included as case group. Age and sex matched 30 subjects were selected from office workers of Heidelberg Cement Bangladesh Ltd. and Chittagong Medical College as control group. To assess liver function 3 ml of venous blood was collected from each subject under aseptic precaution. Liver enzymes were assessed. After compiling data, statistical analyses were done by using SPSS for windows version-25. Unpaired student’s‘t’ test was done as test of significance. \u0000Results: Liver enzymes like serum AST and serum ALT was lower in case group than control group within normal range and it was not statistically significant. Serum ALT was significantly higher in case group than control. It was also within normal range. \u0000Conclusion: This study suggests that liver function might not be impaired by cement dust. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 22-24","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81238823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apert Syndrome: A Case Report","authors":"R. Chowdhury, Md. Akram Ullah, Shirin Akhter Ruhina, Fahmida Jahan Gazi, Tanuka Barua, Priyanka Chowdhury","doi":"10.3329/cmoshmcj.v21i2.63142","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63142","url":null,"abstract":"Background : Apert syndrome is a rare autosomal dominant disorder characterized by craniosynostosis, facial dysmorphism and syndactyly of hands and feet. Eugene Apert in 1906 describe the syndrome acrocephalosyndactyly. \u0000Case Presentation : The reporting case was a 3 months old female baby presented with early fusion of all cranial bone, facial dimorphism like hypertelorism, cleft palate and syndactyly of both hands and feet. There was some bony defect also found in radioligy. \u0000Conclusion : It is a noncurable disease but treat with multidisciplinary approach can reduce the complication and prevention can be done by genetic counselling and antenatal ultrasonography. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 60-63 ","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88594228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fasting Serum Lipid Profile and Its Association with Serum High Sensitivity C-Reactive Protein in Type II Diabetes Mellitus","authors":"Nadia Hossain, Farhena Ahmed, Tasmia Sharnin, Pijush Karmakar","doi":"10.3329/cmoshmcj.v21i2.63126","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63126","url":null,"abstract":"Background: Patients with type II diabetes mellitus frequently have altered lipid profiles. Detection of serum high sensitivity C-reactive protein is associated with cardiovascular events in type II DM as the presence of subclinical inflammation. The study was undertaken to observe the fasting serum lipid profile level and its association with serum hs-CRP in type II DM. \u0000Materials and methods: A hospital-based observational study was carried out in the Outpatient Department of Endocrinology, Chittagong Medical College Hospital and Department of Biochemistry, Chittagong Medical College. By using non-probability consecutive sampling, a total of 176 participants were enrolled, with 126 type II DM and 50 in the control group. Plasma glucose and serum hs-CRP, fasting serum lipid profile was estimated. \u0000Results: The mean serum hs-CRP level in patients with type II DM (9.1 ± 0.36 mg/L) was significantly (p 0.0001) elevated as compared to control (4.3 ± 0.09 mg/L). The result showed an increase in serum total cholesterol, serum triglycerides, serum HDLC and serum LDL-C among the diabetic patients when compared with the healthy control group. Serum hs-CRP was significantly associated with serum TG and serum LDL-C in type II diabetics. Moreover, serum hs-CRP was found to have a significant positive correlation with serum LDL-C and serum TG. Only 77.78% of patients had increased LDL-C but altogether 85.71% of patients had increased serum hs-CRP levels. \u0000Conclusion: According to the findings of this study,increased serum hs-CRP was well associated and positively correlated with components of the fasting lipid profile, indicating early identification of cardiovascular risk among type II diabetics. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 35-39","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86022595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}