Effects of Cement Dust on Liver Function Parameters of Some Cement Factory Workers

Shahin Akhter, Md Sakhawat Mahmud Khan, M. Akhter, Arunima Datta, M. Begum
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Abstract

Background: Cement dust is one of the major air pollutants and its exposure causes various problems. It has deleterious effect on vital organs and may affect liver function. This study was done to assess the effects of cement dust on liver function parameters of cement factory workers. Materials and methods: This case control study was conducted in the Department of Physiology, Chittagong Medical College, Chattogram in collaboration with Heidelberg Cement Bangladesh Ltd. Chattogram during January 2018 to December 2018. For these, 30 cement exposed workers of Heidelberg Cement Bangladesh Ltd. aged between 20-45 years were included as case group. Age and sex matched 30 subjects were selected from office workers of Heidelberg Cement Bangladesh Ltd. and Chittagong Medical College as control group. To assess liver function 3 ml of venous blood was collected from each subject under aseptic precaution. Liver enzymes were assessed. After compiling data, statistical analyses were done by using SPSS for windows version-25. Unpaired student’s‘t’ test was done as test of significance. Results: Liver enzymes like serum AST and serum ALT was lower in case group than control group within normal range and it was not statistically significant. Serum ALT was significantly higher in case group than control. It was also within normal range. Conclusion: This study suggests that liver function might not be impaired by cement dust. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 22-24
水泥粉尘对部分水泥厂工人肝功能指标的影响
背景:水泥粉尘是主要的大气污染物之一,其暴露会引起各种问题。它对重要器官有有害影响,并可能影响肝功能。本研究旨在评估水泥粉尘对水泥厂工人肝功能参数的影响。材料和方法:本病例对照研究在吉大港医学院生理学系进行,Chattogram与海德堡水泥孟加拉国有限公司合作。2018年1月至2018年12月期间的Chattogram。本研究以海德堡水泥孟加拉国有限公司30名年龄在20-45岁之间的水泥暴露工人为病例组。选取年龄、性别相匹配的海德堡水泥孟加拉国有限公司和吉大港医学院办公室职员30名作为对照组。为评估肝功能,每位受试者在无菌预防下采集静脉血3ml。评估肝酶。数据整理后,采用SPSS for windows version-25进行统计分析。Unpaired student’t检验作为显著性检验。结果:病例组血清AST、ALT等肝酶在正常范围内低于对照组,差异无统计学意义。病例组血清ALT显著高于对照组。它也在正常范围内。结论:本研究提示水泥粉尘可能不会损害肝功能。上海医科大学医学院;月,(2);2022年7月;第22 - 24页
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