Chemical Research in Chinese Universities最新文献_第7页

Cis- and Trans-Coordination Assembly of Nitrogen Heterocycle with Copper(II) and Silver(I) 氮杂环与铜(II)和银(I)的顺式和反式配位组装

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60001-5

Di TAN , Gui-ping TAN , Xiao-chun HUANG , Shan-ling TONG , Ke-er YANG , Yan YAN

引用次数: 1

Lethal Effect of Benzene Nitrogen Mustard Glucoside Derivate on K562 Cells 苯氮芥糖苷衍生物对K562细胞的杀伤作用

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60023-4

Tie-mei LIU , Guang-ze ZHU , Jin-song ZHOU , Zhi SUN , Feng XIE

{"title":"Lethal Effect of Benzene Nitrogen Mustard Glucoside Derivate on K562 Cells","authors":"Tie-mei LIU , Guang-ze ZHU , Jin-song ZHOU , Zhi SUN , Feng XIE","doi":"10.1016/S1005-9040(09)60023-4","DOIUrl":"10.1016/S1005-9040(09)60023-4","url":null,"abstract":"<div>A new synthesized benzene nitrogen mustard was converted into glycosyl donor-trichloroacetimidate that was glycosylated with p-nitrophenol(glycosyl donors) to form β-lactosyl p-nitrobenzene under the protection of acetyl in a stereoselective manner, was prepared and evaluated for its cytotoxicity towards cultured K562 cell line. Methylthiazoy tetrazolium(MTT) assay, transmission electron microscopy(TEM), flow cytometry(FCM) and immunohistochemistry were utilized to explore the mechanisms of how the compound arrests the growth of HCT-T cells. This new synthesed benzene nitrogen mustard glucoside derivate(BNMGD) presented a lower toxicity to normal cells, but is significantly more toxic to K562 cells compared with nitrogen mustard, meanwhile it can induce the apoptosis of K562 cells. These results indicate that the new synthesized BNMGD can inhibit the growth of K562 cells and induce the apoptosis, and its cytotoxicity towards cultured K562 cell line is much more effective than that of nitrogen mustard.</div>","PeriodicalId":9785,"journal":{"name":"Chemical Research in Chinese Universities","volume":"24 6","pages":"Pages 762-766"},"PeriodicalIF":3.1,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1005-9040(09)60023-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56328917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effective VTeO/SBA-15 Catalyst Prepared by Precursor Method for the Selective Oxidation of Propane to Acrolein 前驱体法制备丙烷选择性氧化制丙烯醛的有效VTeO/SBA-15催化剂

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60030-1

Mao-ying FENG, Chuan-jing HUANG, Wei-zheng WENG, Hui-lin WAN, Qin XU, Zhao-hui ZHOU

引用次数: 1

Synthesis, Characterization, and Properties of Supported Tungstozincate Bridged by Co(II) Complex Fragment Co(II)配合物桥接负载型钨酸盐的合成、表征及性能研究

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60002-7

Kun LIU , Jia LI , Hong-bo LIU , Ya-guang CHEN

{"title":"Synthesis, Characterization, and Properties of Supported Tungstozincate Bridged by Co(II) Complex Fragment","authors":"Kun LIU , Jia LI , Hong-bo LIU , Ya-guang CHEN","doi":"10.1016/S1005-9040(09)60002-7","DOIUrl":"10.1016/S1005-9040(09)60002-7","url":null,"abstract":"<div>[Co11(phen)3]2[{(ZnW12O40)Co11(phen)2(H2O)}2Co11(trien)2(NaH2O)2]·3H2O was synthesized via hydrothermal technique and characterized with elemental analyses, IR spectroscopy, TGA-DTA, and variable temperature magnetic susceptibility. The compound crystallized in the monoclinic system with the space group P21/n, a= 1.8210 nm, b=2.3592 nm, c=2.2932 nm, β=110.31°, V=9.239 nm3, Z=2, R1=0.0827. The compound consists of two coordination cations, three lattice water molecules, and a macroanion [{(ZnW12W40)Co(phen)2(H2O)}2Co(C6H18N4)2·(NaH2O)2]4- in which each supported Keggin anion [(ZnW12O40Co11(phen)2(H2O)]4- acts as a ligand to coordinate to central bridging Co2+ ion via a terminal oxygen atom. Hydrogen bonds are responsible for the construction of 3D architecture of the compound. The compound is paramagnetic with a weak antiferromagnetic interaction(ϑ=−46.796 K).</div>","PeriodicalId":9785,"journal":{"name":"Chemical Research in Chinese Universities","volume":"24 6","pages":"Pages 668-671"},"PeriodicalIF":3.1,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1005-9040(09)60002-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56328652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Vacuum Ultraviolet Excited Photoluminescence Properties of Y2O2S:Eu3+,Bi3+ Phosphor Y2O2S:Eu3+，Bi3+荧光粉的真空紫外激发光致发光性能

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60005-2

Zhi-long WANG, Yu-hua WANG, Jia-chi ZHANG

{"title":"Vacuum Ultraviolet Excited Photoluminescence Properties of Y2O2S:Eu3+,Bi3+ Phosphor","authors":"Zhi-long WANG, Yu-hua WANG, Jia-chi ZHANG","doi":"10.1016/S1005-9040(09)60005-2","DOIUrl":"10.1016/S1005-9040(09)60005-2","url":null,"abstract":"<div>As an Hg-free lamp using phosphor, the Bi3+ and Eu3+ co-doped Y2O2S phosphors were prepared and their luminescence properties under vacuum ultraviolet(VUV) excitation were investigated. The VUV photoluminescent intensity of Y2O2S:Eu3+ was weak, however, considerably stronger red emission at 626 nm with good color purity was observed in Y2O2S:Eu3+,Bi3+ systems. Investigation on the photoluminescence reveals that the strong VUV luminescence of Y2O2S:Eu3+Bi3+ at 147 nm is mainly because the Bi3+ acts as a medium and effectively performs the energy transfer process: Y3+-O2-→Bi3+→Eu3+, while the intense emission band at 172 nm is attributed to the absorption of the characteristic 1S0-1P1 transition of Bi3+ and the direct energy transfer from Bi3+ to Eu3+. The Y2O2S:Eu3+,Bi3+ shows excellent VUV optical properties compared with the commercial (Y, Gd)BO3:Eu3+. Thus, the Y2O2S:Eu3+,Bi3+ can be a potential red VUV-excited candidate applied in Hg-free lamps for backlight of liquid crystal display.</div>","PeriodicalId":9785,"journal":{"name":"Chemical Research in Chinese Universities","volume":"24 6","pages":"Pages 679-682"},"PeriodicalIF":3.1,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1005-9040(09)60005-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56328681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Temperature and Energy on Stability of Oligomeric Enzyme Probed on Electrospray Ionization Mass Spectrometry 温度和能量对电喷雾质谱检测低聚酶稳定性的影响

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60025-8

Zhi-li LI

{"title":"Effects of Temperature and Energy on Stability of Oligomeric Enzyme Probed on Electrospray Ionization Mass Spectrometry","authors":"Zhi-li LI","doi":"10.1016/S1005-9040(09)60025-8","DOIUrl":"10.1016/S1005-9040(09)60025-8","url":null,"abstract":"<div>Escherichia coli 3-Deoxy-D-manno-octulosonate 8-phosphate(KDO8P) synthase catalyzed the condensation reaction between D-arabinose 5-phosphate(A5P) and phosphoenolpyruvate(PEP) to form KDO8P and inorganic phosphate(Pi). The noncovalent tetrameric association of KDO8P synthase was observed and dissociated in gas phase by means of electrospray ionization mass spectrometry under the very “soft” conditions. The results indicate that PEP-bound enzyme generated abundant tetrameric species as well as monomeric species at the “soft” conditions, whereas, the unbound enzyme favored the formation of a dimeric species. The mass spectra of the mixture of the enzyme with one of substrates, PEP, and A5P or one of products, KDO8P and Pi show that the complex of the unbound enzyme with PEP or Pi was prone to the formation of a monomeric species, whereas, that of the unbound enzyme with A5P or KDO8P was similar to the unbound enzyme. The intensity of the dimeric species increased with the increase of temperature at a collision voltage of 10 V. Taken together, the results presented here suggest that mass spectrometry will be a powerful tool to explore subtile conformational changes and/or subunit-subunit interactions of multiprotein assembly induced by ligand-binding and/or the changes of environmental conditions.</div>","PeriodicalId":9785,"journal":{"name":"Chemical Research in Chinese Universities","volume":"24 6","pages":"Pages 771-777"},"PeriodicalIF":3.1,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1005-9040(09)60025-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56328939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorescent Switch Behavior of 1, 2-Bis(4-pyridyl) Ethylene Controlled by pH in Aqueous Solution 1,2 -二(4-吡啶基)乙烯在水溶液中pH控制的荧光开关行为

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60012-X

Wen-sheng ZOU , Qian-jin SHEN , Yu WANG , Wei-jun JIN

{"title":"Fluorescent Switch Behavior of 1, 2-Bis(4-pyridyl) Ethylene Controlled by pH in Aqueous Solution","authors":"Wen-sheng ZOU , Qian-jin SHEN , Yu WANG , Wei-jun JIN","doi":"10.1016/S1005-9040(09)60012-X","DOIUrl":"10.1016/S1005-9040(09)60012-X","url":null,"abstract":"<div>With the decrease of pH value from 8.45 to −1.0, the UV-Vis absorption and fluorescent spectra of 1,2-bis(4-pyridyl) ethylene(BPE) took on the same changing trend at four different successive pH stages: 8.45—7.20, 7.20—5.62, 5.62—2.60, and 2.60—1.0, namely, no change, decrease, increase, and decrease again. Among these, in a range of 7.20—5.62, the fluorescence wavelength blueshifted from 418 to 359 nm, but the UV-Vis absorption wavelength, in contrast, redshifted from 285 to 298 nm. The fluorescence intensity of BPE had a drop even to quench upon a decline in the pH value from 2.60 to −1.0 probably owing to its cation-π interaction to reduce the π electron cloud density of BPE. Two dissociation constants, pKa1(4.30±0.01) and pKa2(5.65±0.04), were obtained based on fluorescence data. The changes of fluorescence spectra indicate that BPE has “off-on-off” switch behavior. The fluorescent spectra of BPE were nearly independent on the presence of α- and β-cyclodextrins.</div>","PeriodicalId":9785,"journal":{"name":"Chemical Research in Chinese Universities","volume":"24 6","pages":"Pages 712-716"},"PeriodicalIF":3.1,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1005-9040(09)60012-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56328775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Synthesis of an Anti-AIDs Drug Delavirdine Derivate, Resdelasu 抗艾滋病药物Delavirdine衍生物Resdelasu的合成

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60016-7

Qing-xiang GUAN , Li-peng HE , Xi WANG , Wen-yan ZHANG , En-si WANG , Xiang-hui YU

引用次数: 0

Preparation of 5-Fluorouracil Loaded Polylactide-co-glycolide-co-methoxy Poly(ethylene glycol) (PLGA-mPEG) Nanoparticles via High Speed Shearing 高速剪切法制备负载5-氟尿嘧啶的聚乳酸-共乙二醇-共甲氧基聚乙二醇纳米颗粒

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60032-5

Hang LIN , Hui REN , Xi-shan WANG , Qing-chao TANG , Jun TANG , Ce WANG

引用次数: 3

Electrochemical Oxidation of Ammonia on Ir Anode in Potential Fixed Electrochemical Sensor 电位固定型电化学传感器中氨在Ir阳极上的电化学氧化

IF 3.1 4区化学

Chemical Research in Chinese Universities Pub Date : 2008-11-01 DOI: 10.1016/S1005-9040(09)60027-1

Yi-ping HAN , Peng LUO , Chen-xin CAI , Lei XIE , Tian-hong LU

{"title":"Electrochemical Oxidation of Ammonia on Ir Anode in Potential Fixed Electrochemical Sensor","authors":"Yi-ping HAN , Peng LUO , Chen-xin CAI , Lei XIE , Tian-hong LU","doi":"10.1016/S1005-9040(09)60027-1","DOIUrl":"10.1016/S1005-9040(09)60027-1","url":null,"abstract":"<div>Ir catalyst possesses a good electrocatalytic activity and selectivity for the oxidation of NH3 and/or NH4OH at Ir anode in the potential fixed electrochemical sensor with the neutral solution. Owing to the same electrochemical behavior of NH3 and NH4OH in a NaClO4 solution, NH4OH can be used instead of NH3 for the experimental convenience. It was found that the potential of the oxidation peak of NH4OH at the Ir/GC electrode in NaClO4 solutions is at about 0.85 V, and the current density of the oxidation peak of NH4OH is linearly proportional to the concentration of NH4OH. The electrocatalytic oxidation of NH4OH is diffusion-controlled. Especially, Ir has no electrocatalytic activity for the CO oxidation, illustrating that CO does not interfere in the measurement of NH4OH and the potential fixed electrochemical NH3 sensor with the neutral solution, and the anodic Ir catalyst possesses a good selectivity. Therefore, Ir may have practical application in the potential fixed electrochemical NH3 sensor with the neutral solution.</div>","PeriodicalId":9785,"journal":{"name":"Chemical Research in Chinese Universities","volume":"24 6","pages":"Pages 782-785"},"PeriodicalIF":3.1,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1005-9040(09)60027-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56328976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3