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In silico Evaluation of WWC1 in Melanoma Using Bioinformatic Analyses 基于生物信息学分析的黑色素瘤WWC1的计算机评价
Central European Journal of Biology Pub Date : 2022-12-29 DOI: 10.26650/eurjbiol.2022.1168881
Dilara Kamer Çolak, Ufuk Ünal, S. Bolkent
{"title":"In silico Evaluation of WWC1 in Melanoma Using Bioinformatic Analyses","authors":"Dilara Kamer Çolak, Ufuk Ünal, S. Bolkent","doi":"10.26650/eurjbiol.2022.1168881","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1168881","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89051136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thioredoxin-Interacting Protein: The Redoxissome Complex in Glomerular Lesion 硫氧还蛋白相互作用蛋白:肾小球病变中的氧化还酶体复合物
Central European Journal of Biology Pub Date : 2022-12-21 DOI: 10.26650/eurjbiol.2022.1163544
Gabriel Pereira, Emily Pereira Dos Santos, Maria Ruy Barbosa, S. Arioni, Thabata Caroline de Oliveira Santos, D. T. de Resende e Silva, J. H. Henao Agudelo, M. P. Pinho Franco, Ricardo Fernandez, Rafael Pereira, Danilo Souza de Almeida
{"title":"Thioredoxin-Interacting Protein: The Redoxissome Complex in Glomerular Lesion","authors":"Gabriel Pereira, Emily Pereira Dos Santos, Maria Ruy Barbosa, S. Arioni, Thabata Caroline de Oliveira Santos, D. T. de Resende e Silva, J. H. Henao Agudelo, M. P. Pinho Franco, Ricardo Fernandez, Rafael Pereira, Danilo Souza de Almeida","doi":"10.26650/eurjbiol.2022.1163544","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1163544","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81958132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Anti-Cancer Effects of Trigonella foenum in Neuroblastoma Cell Line 泡沫三角铃菌对神经母细胞瘤细胞系的抗癌作用
Central European Journal of Biology Pub Date : 2022-12-20 DOI: 10.26650/eurjbiol.2022.1167842
İrem Ürkmez, Hatice Karahan Coven, Aslı Eldem, M. Pehlivan
{"title":"Anti-Cancer Effects of Trigonella foenum in Neuroblastoma Cell Line","authors":"İrem Ürkmez, Hatice Karahan Coven, Aslı Eldem, M. Pehlivan","doi":"10.26650/eurjbiol.2022.1167842","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1167842","url":null,"abstract":"Objective: Current approaches focus on the use of natural compounds in plants in the treatment of cancer. Trigonella foenum (Fenugreek) is mainly used in medicine, food, and cosmetics due to its bioactive and aromatic compounds. Many compounds with medicinal effects are found in Fenugreek seeds. These compounds have been demonstrated to be effective on numerous cancer cells. Neuroblastoma is one of the most common extracranial solid malignancies in children. In our study, the effects of Fenugreek on cell cytotoxicity, cell damage, migration, and sphere formation in neuroblastoma cells were investigated. Materials and Methods: The powder extract was dissolved in DMEM and filtered to prepare a stock solution of Fenugreek. We used MTT assay for the detection of cytotoxic effects of Fenugreek on SH-SY5Y cells, crystal violet staining for the analysis of morphological change in cells, wound healing test for the cell migration analysis, and agarose gel electrophoresis for detecting DNA damage. We created a spheroid to test the effect we observed in 2D culture, in 3D culture as well. Results: The findings of our study showed that Fenugreek treatments caused significant reductions in cell proliferation and migration capacities in 2D neuroblastoma cells at IC 50 (1500 μg/ml) doses, respectively. In addition Fenugreek changed cell morphology and increased DNA fragmentation. Furthermore, Fenugreek caused disruption of 3D spheroid formation of SHSY-5Y cells in a dose- and time-dependent manner. Conclusion: The determination of the anti-cancer effect of Fenugreek on neuroblastoma cancer may be a useful and feasible intervention in neuroblastoma patients in the light of further studies and with the help of new nano drug delivery systems.","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90224564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Records for Microalgae Species of the Turkish Seas Under the Effect of Intense Mucilage in the Sea of Marmara 马尔马拉海强烈黏液作用下土耳其海微藻物种新记录
Central European Journal of Biology Pub Date : 2022-12-20 DOI: 10.26650/eurjbiol.2022.1195227
Turgay Durmuş, N. Balkıs, S. Tas, Fatma Bayram Partal, M. Balcı, C. Dalyan, M. Sari
{"title":"New Records for Microalgae Species of the Turkish Seas Under the Effect of Intense Mucilage in the Sea of Marmara","authors":"Turgay Durmuş, N. Balkıs, S. Tas, Fatma Bayram Partal, M. Balcı, C. Dalyan, M. Sari","doi":"10.26650/eurjbiol.2022.1195227","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1195227","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"158 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78139807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Epibrassinolide Triggers Apoptotic Cell Death in SK-N-AS Neuroblastoma Cells by Targeting GSK3β in a ROS Generation-Dependent Way 表油菜素内酯通过ROS生成依赖的方式靶向GSK3β触发SK-N-AS神经母细胞瘤细胞凋亡
Central European Journal of Biology Pub Date : 2022-12-15 DOI: 10.26650/eurjbiol.2022.1191701
Pınar Obakan Yerlİkaya, Shafaq Naxmedova
{"title":"Epibrassinolide Triggers Apoptotic Cell Death in SK-N-AS Neuroblastoma Cells by Targeting GSK3β in a ROS Generation-Dependent Way","authors":"Pınar Obakan Yerlİkaya, Shafaq Naxmedova","doi":"10.26650/eurjbiol.2022.1191701","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1191701","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76150474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Apocynin against Monosodium Glutamate-Induced Oxidative Damage in Rat Kidne 罗布麻苷对谷氨酸钠所致大鼠肾脏氧化损伤的影响
Central European Journal of Biology Pub Date : 2022-12-15 DOI: 10.26650/eurjbiol.2022.1148934
M. Acikel Elmas, G. Özgün, Özlem BİNGÖL ÖZAKPINAR, Zozan Guleken, S. Arbak
{"title":"Effects of Apocynin against Monosodium Glutamate-Induced Oxidative Damage in Rat Kidne","authors":"M. Acikel Elmas, G. Özgün, Özlem BİNGÖL ÖZAKPINAR, Zozan Guleken, S. Arbak","doi":"10.26650/eurjbiol.2022.1148934","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1148934","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78916688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personalized Medicine: A Solution for Today and Tomorrow 个性化医疗:今天和明天的解决方案
Central European Journal of Biology Pub Date : 2022-12-02 DOI: 10.26650/eurjbiol.2021.1110344
B. Dalbayrak, Mustafa Metiner
{"title":"Personalized Medicine: A Solution for Today and Tomorrow","authors":"B. Dalbayrak, Mustafa Metiner","doi":"10.26650/eurjbiol.2021.1110344","DOIUrl":"https://doi.org/10.26650/eurjbiol.2021.1110344","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90346551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myrtus communis L. Extract Ameliorates High Fat Diet Induced Kidney and Bladder Damage by Inhibiting Oxidative Stress and Inflammation 桃金娘提取物通过抑制氧化应激和炎症改善高脂饮食引起的肾和膀胱损伤
Central European Journal of Biology Pub Date : 2022-12-02 DOI: 10.26650/eurjbiol.2022.1111191
Fatma Kanpalta, B. Ertaş, A. Şen, D. Akakın, G. Şener, F. Ercan
{"title":"Myrtus communis L. Extract Ameliorates High Fat Diet Induced Kidney and Bladder Damage by Inhibiting Oxidative Stress and Inflammation","authors":"Fatma Kanpalta, B. Ertaş, A. Şen, D. Akakın, G. Şener, F. Ercan","doi":"10.26650/eurjbiol.2022.1111191","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1111191","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73860399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammation Parameters, Xanthine Oxidase and Anti-Xanthine Oxidase Antibodies in Synovial Fluid of Patients Suffering from Arthritis 关节炎患者滑液炎症参数、黄嘌呤氧化酶及抗黄嘌呤氧化酶抗体
Central European Journal of Biology Pub Date : 2022-11-24 DOI: 10.26650/eurjbiol.2022.1097938
N. Hanachi, L. Arrar
{"title":"Inflammation Parameters, Xanthine Oxidase and Anti-Xanthine Oxidase Antibodies in Synovial Fluid of Patients Suffering from Arthritis","authors":"N. Hanachi, L. Arrar","doi":"10.26650/eurjbiol.2022.1097938","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1097938","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86971237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Silico Analysis of BMAL1 and CLOCK SNPs in the Ensembl Database 集成数据库中BMAL1和CLOCK snp的芯片分析
Central European Journal of Biology Pub Date : 2022-11-23 DOI: 10.26650/eurjbiol.2022.1164864
Şeref Gül
{"title":"In Silico Analysis of BMAL1 and CLOCK SNPs in the Ensembl Database","authors":"Şeref Gül","doi":"10.26650/eurjbiol.2022.1164864","DOIUrl":"https://doi.org/10.26650/eurjbiol.2022.1164864","url":null,"abstract":"","PeriodicalId":9711,"journal":{"name":"Central European Journal of Biology","volume":"143 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86780236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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