Case Reports in Rheumatology最新文献

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Enthesitis in Bowel-Associated Dermatosis-Arthritis Syndrome in an Ulcerative Colitis Patient 溃疡性结肠炎患者肠道相关皮肤病-关节炎综合征并发肠炎
Case Reports in Rheumatology Pub Date : 2022-04-12 DOI: 10.1155/2022/4556250
Khalid S Alshahrani, A. Almohaya, Rayan S. Hussein, R. H. Ali
{"title":"Enthesitis in Bowel-Associated Dermatosis-Arthritis Syndrome in an Ulcerative Colitis Patient","authors":"Khalid S Alshahrani, A. Almohaya, Rayan S. Hussein, R. H. Ali","doi":"10.1155/2022/4556250","DOIUrl":"https://doi.org/10.1155/2022/4556250","url":null,"abstract":"Bowel-associated dermatosis-arthritis syndrome (BADAS) is a rare and recurrent neutrophilic dermatosis condition. Due to the rarity of this syndrome and the difficulty of the disease recognition and management, there was no clear reported incidence rate of this syndrome. 20% of patients after ileojejunal bypass surgery for morbid obesity were reported, by Jorizzo et al., to have BADAS. The underlying etiology of BADAS is not fully understood; therefore, the diagnosis of this condition is difficult and the approach for the management as well. Herein, we report a case of BADAS with unusual musculoskeletal presentation.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84319970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Case of Rapidly Progressing Hepatocellular Carcinoma after Administration of JAK Inhibitors to Treat Rheumatoid Arthritis JAK抑制剂治疗类风湿关节炎后快速进展的肝细胞癌一例
Case Reports in Rheumatology Pub Date : 2022-03-29 DOI: 10.1155/2022/6852189
Rioko Migita, Y. Kimoto, Junki Hiura, Yuta Okumura, T. Horiuchi
{"title":"A Case of Rapidly Progressing Hepatocellular Carcinoma after Administration of JAK Inhibitors to Treat Rheumatoid Arthritis","authors":"Rioko Migita, Y. Kimoto, Junki Hiura, Yuta Okumura, T. Horiuchi","doi":"10.1155/2022/6852189","DOIUrl":"https://doi.org/10.1155/2022/6852189","url":null,"abstract":"We report a case of rapidly progressing hepatocellular carcinoma after administration of Janus kinase (JAK) inhibitors to treat rheumatoid arthritis. A 76-year-old man was referred to our Department for pain in multiple joints and was diagnosed with rheumatoid arthritis. Blood tests revealed elevated hepatobiliary enzymes, but various tests revealed no signs suggestive of malignancy. He took baricitinib for 2 months followed by tofacitinib for 4 months. After that, he was diagnosed with hepatocellular carcinoma based on imaging findings and elevated tumor markers. This case showed the possibility of a causal relationship between JAK inhibitors and malignancy.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75584317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hodgkin Lymphoma Mimicking Lumbar Spine Tuberculosis 模拟腰椎结核的霍奇金淋巴瘤
Case Reports in Rheumatology Pub Date : 2022-02-25 DOI: 10.1155/2022/5298960
H. J. Djossou, M. A. Ghassem, H. Toufik, M. Oukabli, A. Bezza, L. Achemlal
{"title":"Hodgkin Lymphoma Mimicking Lumbar Spine Tuberculosis","authors":"H. J. Djossou, M. A. Ghassem, H. Toufik, M. Oukabli, A. Bezza, L. Achemlal","doi":"10.1155/2022/5298960","DOIUrl":"https://doi.org/10.1155/2022/5298960","url":null,"abstract":"Introduction The clinical manifestations of Hodgkin lymphoma (HL) can closely mimic spine and lymph node tuberculosis (TB). Case Description. A 48-year-old man was initially treated for retroperitoneal lymph nodes TB, and this diagnosis was made without bacteriological and histopathological confirmation. After four months of regular therapy for TB, he did not improve and was admitted to our department for lumbar spine pain. We first made diagnosis of tuberculous spondylodiscitis, and anti-TB treatment was strengthened. But, after three weeks of hospitalization, his condition worsened clinically with onset of swelling of the left supraclavicular lymph node. So, after surgical excision and anatomopathological examination of the lymph node, the diagnosis of nodular sclerosis classic Hodgkin lymphoma was made. He was treated by chemotherapy, and his condition improved significantly after the first 2 cycles of chemotherapy. Conclusion Repeated investigations may be helpful in establishing a correct diagnosis and starting an effective treatment in this highly curable disease.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84701396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Erratum to “A Rare Case of Fatal Hemorrhagic Stroke in a Young Female with Early Mixed Connective Tissue Disease” “1例年轻女性早期混合性结缔组织病致死性出血性中风”的勘误
Case Reports in Rheumatology Pub Date : 2022-02-23 DOI: 10.1155/2022/9762151
James R. Agapoff IV
{"title":"Erratum to “A Rare Case of Fatal Hemorrhagic Stroke in a Young Female with Early Mixed Connective Tissue Disease”","authors":"James R. Agapoff IV","doi":"10.1155/2022/9762151","DOIUrl":"https://doi.org/10.1155/2022/9762151","url":null,"abstract":"[This corrects the article DOI: 10.1155/2021/5321438.].","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"193 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78080485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemosis as an Initial Presentation of Systemic Lupus Erythematosus. 化脓是系统性红斑狼疮的初始表现。
Case Reports in Rheumatology Pub Date : 2022-02-15 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4912092
Carvy Floyd Luceno, Minho Yu, Daniel I Kim, Vaneet K Sandhu
{"title":"Chemosis as an Initial Presentation of Systemic Lupus Erythematosus.","authors":"Carvy Floyd Luceno,&nbsp;Minho Yu,&nbsp;Daniel I Kim,&nbsp;Vaneet K Sandhu","doi":"10.1155/2022/4912092","DOIUrl":"https://doi.org/10.1155/2022/4912092","url":null,"abstract":"<p><p>Systemic lupus erythematosus (SLE) can present in a multitude of ways, which can be confounding and misleading for a clinician. Chemosis as an initial presentation is rare and has only been documented on a few case reports. However, when present, simultaneous involvement of other organs is likely. We present a previously healthy 29-year-old male who presented with severe bilateral chemosis and was subsequently diagnosed with SLE and antiphospholipid syndrome. Complications included multiple acute cerebral infarcts, lupus psychosis, lupus pleuritis, and lupus nephritis. The patient recovered well with appropriate treatment and chemosis ultimately resolved. Recognizing chemosis as an initial presentation of SLE is vital for appropriate evaluation and timely treatment to prevent disease progression.</p>","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2022 ","pages":"4912092"},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39834673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination. mRNA SARS-CoV-2疫苗接种后新发系统性红斑狼疮。
Case Reports in Rheumatology Pub Date : 2022-02-11 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6436839
Laisha Báez-Negrón, Luis M Vilá
{"title":"New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination.","authors":"Laisha Báez-Negrón,&nbsp;Luis M Vilá","doi":"10.1155/2022/6436839","DOIUrl":"https://doi.org/10.1155/2022/6436839","url":null,"abstract":"<p><p>Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease resulting from the interaction of genetic and environmental factors. In addition, some antiviral vaccines have been associated with the onset of SLE. Few cases of SLE occurring after SARS-CoV-2 mRNA have been reported. Herein, we report the case of a 27-year-old woman with type I diabetes mellitus and family history of SLE who presented with symmetric inflammatory polyarthritis of the proximal interphalangeal joints, metacarpophalangeal joints, wrists, knees, and ankles two weeks after receiving the second dose of the SARS-CoV-2 mRNA-1273 vaccine. Laboratory results revealed positive antinuclear, anti-dsDNA, anti-Ro, and anti-La/SSB antibodies and low C4 levels. She was initially treated with low-dose prednisone and hydroxychloroquine. Hydroxychloroquine was discontinued after she developed an urticarial rash. Subsequently, mycophenolate mofetil was added after she developed proteinuria. This case highlights the importance of considering the diagnosis of SLE in patients who present with inflammatory polyarthritis after COVID-19 vaccination.</p>","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2022 ","pages":"6436839"},"PeriodicalIF":0.0,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39940408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Cardiac Tamponade: A Rare Manifestation of Familial Mediterranean Fever. 心脏填塞:家族性地中海热的一种罕见表现。
Case Reports in Rheumatology Pub Date : 2022-02-07 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8334375
Abdolreza Malek, Tina Zeraati, Ariane Sadr-Nabavi, Niloofar Vakili, Mohammad Reza Abbaszadegan
{"title":"Cardiac Tamponade: A Rare Manifestation of Familial Mediterranean Fever.","authors":"Abdolreza Malek,&nbsp;Tina Zeraati,&nbsp;Ariane Sadr-Nabavi,&nbsp;Niloofar Vakili,&nbsp;Mohammad Reza Abbaszadegan","doi":"10.1155/2022/8334375","DOIUrl":"https://doi.org/10.1155/2022/8334375","url":null,"abstract":"<p><p>Familial Mediterranean fever (FMF) typically presents with recurrent attacks of fever and serosal inflammation with peritoneum, pleura, and synovium. We usually do not expect pericardial involvement at the early stages. FMF is an autoinflammatory disease, usually inherited with an autosomal recessive pattern. The patients typically have biallelic mutations in the MEFV gene, located on chromosome 16. Colchicine is the first-line treatment of FMF, which not only plays a crucial prophylactic role regarding the attack episodes, but also prevents amyloidosis. Colchicine resistance and intolerance in FMF patients have been rarely reported. Alternative anti-inflammatory agents are understood to be helpful in such cases. We describe a 13-year-old boy referred to our pediatric department complaining of chest pain, dyspnea, and tachycardia. Due to the massive pericardial and pleural effusion, a pericardiocentesis was performed, and a chest tube was inserted. Cardiac tamponade was considered as the initial diagnosis. After a month, he faced another episode of pleuritic chest pain, fever, tachycardia, and pleural and pericardial effusion. Evaluation for probable differential diagnoses including infection, malignancy, and collagen vascular disease showed no remarkable results. Finally, the mutation found by whole exome sequencing was confirmed by direct Sanger sequencing revealing a heterozygote c.44G > C (p.Glu148Gln) mutation in exon 2, confirming the clinical diagnosis of familial Mediterranean fever. Since he seemed to be nonresponsive to the maximum standard dose of colchicine, 100 mg of daily dapsone was added to his treatment regimen, which controlled the attack episodes well. FMF, while rarely initiated with cardiac manifestation, should be considered in patients with any early signs and symptoms of cardiovascular involvement.</p>","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2022 ","pages":"8334375"},"PeriodicalIF":0.0,"publicationDate":"2022-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39641780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine. 一位24岁男性在接种mRNA - COVID-19疫苗后首次出现系统性红斑狼疮。
Case Reports in Rheumatology Pub Date : 2022-02-01 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9698138
Yael Raviv, Batya Betesh-Abay, Yuliya Valdman-Grinshpoun, Liora Boehm-Cohen, Michael Kassirer, Iftach Sagy
{"title":"First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine.","authors":"Yael Raviv,&nbsp;Batya Betesh-Abay,&nbsp;Yuliya Valdman-Grinshpoun,&nbsp;Liora Boehm-Cohen,&nbsp;Michael Kassirer,&nbsp;Iftach Sagy","doi":"10.1155/2022/9698138","DOIUrl":"https://doi.org/10.1155/2022/9698138","url":null,"abstract":"<p><p>The SARS-CoV-2 viral pandemic has had an immeasurable global impact, resulting in over 5 million deaths worldwide. Numerous vaccines were developed in an attempt to quell viral dissemination and reduce symptom severity among those infected. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of antinuclear autoantibodies (ANAs) with heterogenic clinical manifestations, secondary to immune complex deposition in a multitude of organ systems. There are scarcely reported cases of SLE development following COVID-19 mRNA vaccination. We present a case of a 24-year-old male without preexisting conditions or family history of autoimmune disorders, presenting with SLE following the first dose of the SARS-CoV-2 Pfizer-BioNTech mRNA vaccine.</p>","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2022 ","pages":"9698138"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39777114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
One in a Million: A Case Report of Stiff Person Syndrome. 百万分之一:一个僵硬的人综合症病例报告。
Case Reports in Rheumatology Pub Date : 2022-01-13 eCollection Date: 2022-01-01 DOI: 10.1155/2022/7741545
Ruchi Yadav, Neeraj Abrol, Sima Terebelo
{"title":"One in a Million: A Case Report of Stiff Person Syndrome.","authors":"Ruchi Yadav,&nbsp;Neeraj Abrol,&nbsp;Sima Terebelo","doi":"10.1155/2022/7741545","DOIUrl":"https://doi.org/10.1155/2022/7741545","url":null,"abstract":"<p><p>Stiff person syndrome (SPS) is a rare autoimmune disease caused by lack of inhibition to excitatory neurotransmitters in the central nervous system (CNS) leading to inappropriate motor unit firing. The pathophysiology is incompletely understood; however, high titers of antiglutamic acid decarboxylase antibody (anti-GAD Ab) are strongly associated with this disease. We present a 50-year-old woman with a history of ongoing gait and balance issues for 5 years with multiple negative workups. She recently had an acute exacerbation which left her bedbound, unable to move her legs or turn from side to side. After a negative workup at an outside hospital, the patient was discharged to a subacute rehabilitation facility. She then presented to our institution due to worsening of her condition and was ultimately diagnosed with SPS which was successfully treated. We review the case presentation and treatment options in the context of a severe disabling disease presentation.</p>","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2022 ","pages":"7741545"},"PeriodicalIF":0.0,"publicationDate":"2022-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39714920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Extensive Longitudinal Transverse Myelitis after Influenza A Virus Infection in a Patient with Systemic Lupus Erythematosus. 系统性红斑狼疮患者甲型流感病毒感染后广泛的纵横脊髓炎1例。
Case Reports in Rheumatology Pub Date : 2022-01-07 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9506733
Suheiry Márquez, Luis M Vilá
{"title":"Extensive Longitudinal Transverse Myelitis after Influenza A Virus Infection in a Patient with Systemic Lupus Erythematosus.","authors":"Suheiry Márquez,&nbsp;Luis M Vilá","doi":"10.1155/2022/9506733","DOIUrl":"https://doi.org/10.1155/2022/9506733","url":null,"abstract":"<p><p>Transverse myelitis (TM) is a rare complication seen in 1-2% of patients with systemic lupus erythematosus (SLE). Viral infections may cause TM in these patients by causing a dysregulation of their immune system. We report a 30-year-old woman with SLE who had influenza A and a few days later developed urinary retention, bilateral lower extremity paralysis, upper extremity weakness, and optic nerve and macular edema. Magnetic resonance imaging showed C4-T12 hyperintense lesions consistent with TM. She was treated with intravenous methylprednisolone 1 g daily for 3 days and then 6 cycles of monthly intravenous cyclophosphamide. This treatment was followed by oral prednisone. She had a remarkable clinical response. Visual acuity improved to her baseline, and muscle strength almost fully recovered. Clinicians should be aware that viral infections, including influenza, may induce TM. This case highlights the importance of early recognition and prompt treatment with immunosuppressive drugs in such cases.</p>","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2022 ","pages":"9506733"},"PeriodicalIF":0.0,"publicationDate":"2022-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39825663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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