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Case Reports in Rheumatology最新文献

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Massive Intestinal Bleeding in an Adult with IgA Vasculitis Treated with Intravenous Immunoglobulin. 静脉注射免疫球蛋白治疗成人IgA血管炎大出血1例。
Case Reports in Rheumatology Pub Date : 2022-06-14 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9694911
Ibrahim Nassereddin, Ariel Kenig, Yuval Ishay, Hillel Lehmann, Noa Hurvitz, Narmine Elkhateeb, Ram Gelman, Yael Ratz, Inon Sarig, Ido Burstain, Stephanie Benshushan, Fadi Kharouf
{"title":"Massive Intestinal Bleeding in an Adult with IgA Vasculitis Treated with Intravenous Immunoglobulin.","authors":"Ibrahim Nassereddin,&nbsp;Ariel Kenig,&nbsp;Yuval Ishay,&nbsp;Hillel Lehmann,&nbsp;Noa Hurvitz,&nbsp;Narmine Elkhateeb,&nbsp;Ram Gelman,&nbsp;Yael Ratz,&nbsp;Inon Sarig,&nbsp;Ido Burstain,&nbsp;Stephanie Benshushan,&nbsp;Fadi Kharouf","doi":"10.1155/2022/9694911","DOIUrl":"https://doi.org/10.1155/2022/9694911","url":null,"abstract":"<p><p>We report the case of a 29-year-old adult presenting with severe IgA vasculitis, with cutaneous, urologic, and renal manifestations. The late appearance of severe gastrointestinal bleeding dominated the clinical picture, necessitating the administration of tens of units of packed cells and the augmentation of the immunosuppressive protocol. It was not until therapy with intravenous immunoglobulin (IVIG) was introduced that the massive bleeding was controlled. We herein discuss the patient's presentation, the gastrointestinal manifestations of IgA vasculitis, the recommended treatments, and the existent evidence about IVIG therapy.</p>","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":" ","pages":"9694911"},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40388869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Case of Anti-Jo-1 Myositis with Unique Biopsy Findings 具有独特活检结果的抗jo -1肌炎1例
Case Reports in Rheumatology Pub Date : 2022-06-06 DOI: 10.1155/2022/9096643
B. Zulfiqar, Pavel Aksionav, M. Bittar, C. Chapman
{"title":"A Case of Anti-Jo-1 Myositis with Unique Biopsy Findings","authors":"B. Zulfiqar, Pavel Aksionav, M. Bittar, C. Chapman","doi":"10.1155/2022/9096643","DOIUrl":"https://doi.org/10.1155/2022/9096643","url":null,"abstract":"Antisynthetase syndrome (ASS) or anti-Jo-1 antibody syndrome has a classic clinical presentation including arthritis, myositis, interstitial lung disease, mechanic hands, and/or Raynaud's phenomenon. The biopsy findings are distinctive from polymyositis or dermatomyositis. We describe an interesting case of ASS where a patient presented with significant muscle weakness, proteinuria, and interstitial lung disease. She also had positive Ro-52 antibodies in addition to anti-Jo-1 antibodies. Her biopsy findings were consistent with inflammatory necrotizing myositis.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88089465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature 胰腺的痛风:病例报告和文献回顾
Case Reports in Rheumatology Pub Date : 2022-06-03 DOI: 10.1155/2022/3671627
Sooji Choi, N. Voskanian, Jeffrey Ramos, Katherine Nguyen
{"title":"Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature","authors":"Sooji Choi, N. Voskanian, Jeffrey Ramos, Katherine Nguyen","doi":"10.1155/2022/3671627","DOIUrl":"https://doi.org/10.1155/2022/3671627","url":null,"abstract":"We report 3 patients who presented with abnormal pancreatic contents that were initially nondiagnostic but were eventually found to have urate crystal deposition consistent with pancreatic tophaceous gout. Our first case involved an ICU patient who had fever of unknown origin and refractory pancreatic pseudocyst. The other 2 patients presented with abdominal pain associated with a pancreatic mass which mimicked malignancy. After further investigation, we were able to identify pancreatic tophaceous gout as the diagnosis. Initiation of therapy led to resolution of pancreatitis in the first patient and resolution of abdominal pain and decrease in size of a pancreatic mass in the other 2 patients. The recognition of clinical gout involving the pancreas has important implications in the evaluation and care of these patients who are at high risk for tophaceous gout. In addition, the importance of specimen preparation that preserves crystals for viewing is discussed.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83848329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A Case Report of Statin-Induced Immune-Mediated Necrotizing Myopathy Treatment Challenges 他汀类药物诱导的免疫介导的坏死性肌病治疗挑战1例报告
Case Reports in Rheumatology Pub Date : 2022-05-31 DOI: 10.1155/2022/4647227
Anwar I. Joudeh, M. K. Albuni, S. Hassen, Phool Iqbal, Elsaid M Aziz Bedair, Salah Mahdi
{"title":"A Case Report of Statin-Induced Immune-Mediated Necrotizing Myopathy Treatment Challenges","authors":"Anwar I. Joudeh, M. K. Albuni, S. Hassen, Phool Iqbal, Elsaid M Aziz Bedair, Salah Mahdi","doi":"10.1155/2022/4647227","DOIUrl":"https://doi.org/10.1155/2022/4647227","url":null,"abstract":"Statin-induced necrotizing autoimmune myopathy is an immune-mediated necrotizing myopathy related to the use of statins. It is a very rare disease, which usually presents with proximal muscle weakness and frank elevation in creatine kinase levels. Stopping statin and the use of immunosuppressive therapy are considered the mainstay therapy. Use of steroids in patients with inflammatory myopathy can be complicated by steroid-induced myopathy. Herein, we present a case of a 55-year-old patient with statin-induced necrotizing autoimmune myopathy based on the presence of proximal muscle weakness, magnetic resonance findings, suggestive muscle biopsy features, and positive anti-HMGCR autoantibodies. The patient was treated with triple immunosuppressive therapy with a particularly good response to intravenous immunoglobulin. This report highlights the importance of timely diagnosis and early use of combined immunosuppressive therapy to improve patients' outcome affected by this rare disease.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72775688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Three's Company: Coexistence of Silicosis, Scleroderma, and Sjogren Syndrome in a Single Patient 三人行:矽肺、硬皮病和干燥综合征在同一患者中的共存
Case Reports in Rheumatology Pub Date : 2022-05-27 DOI: 10.1155/2022/4487638
Alexis Ziebelman, Shir Raibman-Spector, O. Gendelman
{"title":"Three's Company: Coexistence of Silicosis, Scleroderma, and Sjogren Syndrome in a Single Patient","authors":"Alexis Ziebelman, Shir Raibman-Spector, O. Gendelman","doi":"10.1155/2022/4487638","DOIUrl":"https://doi.org/10.1155/2022/4487638","url":null,"abstract":"We describe a patient who presented with silicosis, scleroderma, and Sjogren syndrome all at the same time. The diagnoses in this case are all associated with continuous exposure to crystalline silica at the patient's workplace. The following report discusses this unique presentation.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79221569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa 7岁女童结节性多动脉炎心肌梗死1例
Case Reports in Rheumatology Pub Date : 2022-04-26 DOI: 10.1155/2022/2175676
Lina Bayazeed, Alaa Felimban, Abdulsalam Alsaiad, Fahd Alsufiani, J. Alqanatish
{"title":"Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa","authors":"Lina Bayazeed, Alaa Felimban, Abdulsalam Alsaiad, Fahd Alsufiani, J. Alqanatish","doi":"10.1155/2022/2175676","DOIUrl":"https://doi.org/10.1155/2022/2175676","url":null,"abstract":"Polyarteritis nodosa (PAN) is a rare systemic vasculitis that affects small to medium-sized arteries. It could affect any organ including the heart. However coronary artery involvements are very rare. We describe a young girl who presented following a histopathological diagnosis of PAN with acute chest pain, high serum troponin, and progressive ischemic changes in the electrocardiogram (ECG). Induction of remission of her disease was done with six-moths Cyclophosphamide infusions and pulse corticosteroids. In addition to anticoagulation and dual antithrombotic therapy, the disease remission was maintained with mycophenolate mofetil which helps in the recovery of coronary disease. Our case illustrates the serious cardiac involvement of PAN in a child that responded to intensive management.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79034568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enthesitis in Bowel-Associated Dermatosis-Arthritis Syndrome in an Ulcerative Colitis Patient 溃疡性结肠炎患者肠道相关皮肤病-关节炎综合征并发肠炎
Case Reports in Rheumatology Pub Date : 2022-04-12 DOI: 10.1155/2022/4556250
Khalid S Alshahrani, A. Almohaya, Rayan S. Hussein, R. H. Ali
{"title":"Enthesitis in Bowel-Associated Dermatosis-Arthritis Syndrome in an Ulcerative Colitis Patient","authors":"Khalid S Alshahrani, A. Almohaya, Rayan S. Hussein, R. H. Ali","doi":"10.1155/2022/4556250","DOIUrl":"https://doi.org/10.1155/2022/4556250","url":null,"abstract":"Bowel-associated dermatosis-arthritis syndrome (BADAS) is a rare and recurrent neutrophilic dermatosis condition. Due to the rarity of this syndrome and the difficulty of the disease recognition and management, there was no clear reported incidence rate of this syndrome. 20% of patients after ileojejunal bypass surgery for morbid obesity were reported, by Jorizzo et al., to have BADAS. The underlying etiology of BADAS is not fully understood; therefore, the diagnosis of this condition is difficult and the approach for the management as well. Herein, we report a case of BADAS with unusual musculoskeletal presentation.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84319970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Case of Rapidly Progressing Hepatocellular Carcinoma after Administration of JAK Inhibitors to Treat Rheumatoid Arthritis JAK抑制剂治疗类风湿关节炎后快速进展的肝细胞癌一例
Case Reports in Rheumatology Pub Date : 2022-03-29 DOI: 10.1155/2022/6852189
Rioko Migita, Y. Kimoto, Junki Hiura, Yuta Okumura, T. Horiuchi
{"title":"A Case of Rapidly Progressing Hepatocellular Carcinoma after Administration of JAK Inhibitors to Treat Rheumatoid Arthritis","authors":"Rioko Migita, Y. Kimoto, Junki Hiura, Yuta Okumura, T. Horiuchi","doi":"10.1155/2022/6852189","DOIUrl":"https://doi.org/10.1155/2022/6852189","url":null,"abstract":"We report a case of rapidly progressing hepatocellular carcinoma after administration of Janus kinase (JAK) inhibitors to treat rheumatoid arthritis. A 76-year-old man was referred to our Department for pain in multiple joints and was diagnosed with rheumatoid arthritis. Blood tests revealed elevated hepatobiliary enzymes, but various tests revealed no signs suggestive of malignancy. He took baricitinib for 2 months followed by tofacitinib for 4 months. After that, he was diagnosed with hepatocellular carcinoma based on imaging findings and elevated tumor markers. This case showed the possibility of a causal relationship between JAK inhibitors and malignancy.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75584317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hodgkin Lymphoma Mimicking Lumbar Spine Tuberculosis 模拟腰椎结核的霍奇金淋巴瘤
Case Reports in Rheumatology Pub Date : 2022-02-25 DOI: 10.1155/2022/5298960
H. J. Djossou, M. A. Ghassem, H. Toufik, M. Oukabli, A. Bezza, L. Achemlal
{"title":"Hodgkin Lymphoma Mimicking Lumbar Spine Tuberculosis","authors":"H. J. Djossou, M. A. Ghassem, H. Toufik, M. Oukabli, A. Bezza, L. Achemlal","doi":"10.1155/2022/5298960","DOIUrl":"https://doi.org/10.1155/2022/5298960","url":null,"abstract":"Introduction The clinical manifestations of Hodgkin lymphoma (HL) can closely mimic spine and lymph node tuberculosis (TB). Case Description. A 48-year-old man was initially treated for retroperitoneal lymph nodes TB, and this diagnosis was made without bacteriological and histopathological confirmation. After four months of regular therapy for TB, he did not improve and was admitted to our department for lumbar spine pain. We first made diagnosis of tuberculous spondylodiscitis, and anti-TB treatment was strengthened. But, after three weeks of hospitalization, his condition worsened clinically with onset of swelling of the left supraclavicular lymph node. So, after surgical excision and anatomopathological examination of the lymph node, the diagnosis of nodular sclerosis classic Hodgkin lymphoma was made. He was treated by chemotherapy, and his condition improved significantly after the first 2 cycles of chemotherapy. Conclusion Repeated investigations may be helpful in establishing a correct diagnosis and starting an effective treatment in this highly curable disease.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84701396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Erratum to “A Rare Case of Fatal Hemorrhagic Stroke in a Young Female with Early Mixed Connective Tissue Disease” “1例年轻女性早期混合性结缔组织病致死性出血性中风”的勘误
Case Reports in Rheumatology Pub Date : 2022-02-23 DOI: 10.1155/2022/9762151
James R. Agapoff IV
{"title":"Erratum to “A Rare Case of Fatal Hemorrhagic Stroke in a Young Female with Early Mixed Connective Tissue Disease”","authors":"James R. Agapoff IV","doi":"10.1155/2022/9762151","DOIUrl":"https://doi.org/10.1155/2022/9762151","url":null,"abstract":"[This corrects the article DOI: 10.1155/2021/5321438.].","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"193 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78080485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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